APIs pour la recherche et les impuretés

Please enquire for more information about 7-Hydroxy-furo[3,4-b]pyrazin-5-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about N-Acetyl o-benzyl 5’-epi lamivudine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Aripiprazole EP Impurity E is a potential impurity of aripiprazole, which is an antipsychotic drug. It has been detected as a major impurity in the drug. Aripiprazole EP Impurity E has been found to be present in human plasma and it is thought that this impurity may have pharmacological effects on humans similar to those of aripiprazole. The detection of this impurity has been achieved using LC-MS/MS methods. This method can be used for wastewater treatment due to the matrix effect of nitrogen atoms. Aripiprazole EP Impurity E may have significant implications in the diagnosis, prevention, and treatment of obesity and other metabolic disorders.

<p>Please enquire for more information about Evixapodlin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Moclobemide N-oxide is a metabolite of moclobemide, an antidepressant drug. It is a white to off-white crystalline powder with a molecular formula of C14H14N2O4 and a molecular weight of 237.3. Moclobemide N-oxide is used in the treatment of depression, but it has not been approved for clinical use in the United States. Moclobemide N-oxide is extensively metabolized by cytochrome P450 enzymes, which may lead to variations in its activity among patients.</p>

Demethylpiperazinyl Sildenafil Sulfonic Acid is a prodrug of sildenafil, which is an organic compound. It is used in the treatment of erectile dysfunction and pulmonary arterial hypertension. This drug is metabolized by hydrolysis to form sildenafil citrate, which then acts as an inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5). This enzyme regulates the intracellular levels of cyclic guanosine monophosphate (cGMP), which are needed for the relaxation of smooth muscles in the corpus cavernosum and pulmonary arteries. Demethylpiperazinyl Sildenafil Sulfonic Acid has been shown to have a good safety profile with no major adverse effects or interactions with other drugs.

Please enquire for more information about 4-[(Dimethylamino)iminomethyl]benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>(-)-Neoisomenthol is a drug product that is a natural product and is found in peppermint oil. It has been shown to have anti-inflammatory and analgesic properties. (-)-Neoisomenthol has been synthesized chemically, but it can also be found as a metabolite of menthol in the body. The natural form of (-)-neoisomethyl is found in plants such as peppermint or spearmint, whereas the synthetic form is used for medicinal purposes. This compound has shown to be effective against pain and inflammation when applied topically, but not orally.</p>

<p>Please enquire for more information about 1-[4-Chloro-2-(2-fluorobenzoyl)phenyl]-2-methyl-1H-imidazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Norchlorprothixene is a psychoactive drug with hypnotic and sedative effects. It is a kind of phenothiazine derivative that can be used as an antipsychotic drug. Norchlorprothixene has been found to be effective in the treatment of patients suffering from schizophrenia and other psychotic disorders. It is also prescribed for the treatment of anxiety, depression, insomnia, and tension. The death rate of norchlorprothixene is unknown. Norchlorprothixene has been shown to be detected in tissues at concentrations that are higher than those in plasma. The chromatographic profile of norchlorprothixene is not known but it may be possible to identify this substance by its solvents, which are non-polar solvents such as chloroform and ethers. Norchlorprothixene can be quantified by immunoassays or by polypeptide assays using electrospray ionization mass spectrom

Flumethasone Impurity 10 is a synthetic drug product. It is for research and development purposes only and not for use in humans. Flumethasone Impurity 10 is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Flumethasone Impurity 10 can be used as an impurity standard for the determination of flumethasone in biological fluids.

D-Fuculose is a medicinal compound that has shown anticancer properties in various studies. It is a kinase inhibitor that targets specific kinases involved in cancer cell growth and survival. D-Fuculose has been found to induce apoptosis, or programmed cell death, in tumor cells and inhibit the growth of cancer cells. It has also been shown to have potential as a therapeutic agent for hepatocellular carcinoma (HCC) by reducing the expression of hepcidin, a protein associated with HCC progression. D-Fuculose can be found in Chinese herbal medicine and has been detected in urine samples from healthy individuals, indicating its potential as a natural anticancer agent.

<p>Moncrotophos is an anticancer agent that has been shown to inhibit the activity of kinases, enzymes that play a crucial role in cell growth and proliferation. This inhibitor has been found to induce apoptosis, or programmed cell death, in cancer cells. Moncrotophos is a synthetic analog of ghrelin, a hormone that regulates appetite and energy balance in humans. It has been shown to have potent inhibitory effects on tumor growth in animal models and human cancer cell lines. In addition to its anticancer properties, Moncrotophos has also been investigated as a potential treatment for other diseases such as diabetes and obesity due to its ability to regulate glucose metabolism. However, caution should be exercised when using this product as it can be toxic if not used properly.</p>

<p>Please enquire for more information about 3,14-Dihydroxy 14β-estra-1,3,5(10)-trien-17-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Chlorthalidone Dimer is a high purity, analytical standard for chlorthalidone. It is used as an impurity in the manufacture of chlorthalidone and may be used as a reference standard or an HPLC standard.

Please enquire for more information about N-(2-Chloroethyl)-1-phenoxy-2-propanamine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about N-Deacetyl-N-formyl agomelatine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Amifostine is a disulfide tetrahydrochloride salt that is used as an antidote to protect the bone marrow during chemotherapy and radiotherapy. Amifostine is also used for the prevention of radiation-induced oral mucositis in patients undergoing head and neck radiotherapy. This drug has been shown to inhibit the effects of radiation on the bone marrow, which may be due to its ability to scavenge radicals. Amifostine also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.

Rivaroxaban N-Hydrolyse N-5-Chlorothiophene-2-carbaldehyde is a drug product that is used as an analytical standard to study the metabolism of rivaroxaban. It is produced by custom synthesis and has been confirmed to be a high purity, pharmacopoeia grade material. This API impurity has CAS No. 1151893-81-0 and is classified as a natural material.

<p>Please enquire for more information about Lp-PLA2-IN-3 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Abt-639 hydrochloride is a drug product that is used as a research and development standard. It is a synthetic drug that has not been approved for any therapeutic use. Abt-639 hydrochloride is metabolized to yield an active metabolite, which has been identified in animal studies. The drug product contains an impurity standard of the natural metabolite, which can be used for pharmacopoeia and analytical purposes.</p>

Butenachlor is a potent anticancer inhibitor that targets tumor kinases. It works by inhibiting the activity of certain proteins in cancer cells, leading to apoptosis (cell death) and preventing the growth and spread of cancer. Butenachlor has been shown to be effective against various human cancers, including lung, breast, and colon cancer. It is an analog of saxagliptin, a drug used to treat type 2 diabetes. Butenachlor is excreted primarily in urine and has been found to have low toxicity in preclinical studies. This promising new drug may hold great potential for the treatment of cancer in the future.

Sorafenib is a drug that is used to treat cancer. Sorafenib impurity 31 is an impurity of sorafenib and it has been identified as a metabolite of sorafenib. It can be synthesized in the laboratory or found in nature. Sorafenib impurity 31 can be used to develop a high purity standard for HPLC analysis, an analytical standard for R&D purposes, and a custom synthesis for niche or drug product development.

<p>Please enquire for more information about 3-Chloro-10-[3-(dimethylamino)propyl]-9(10H)-acridinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Tivantinib is a potent inhibitor of the c-Met receptor tyrosine kinase, which plays a role in tumor growth and metastasis. This Chinese medicinal compound has been shown to have anticancer properties by inducing apoptosis in cancer cells and inhibiting cell cycle progression. Tivantinib has been found to be effective against a range of cancers, including leukemia and human solid tumors. In addition, this compound has been found in urine samples of cancer patients treated with tivantinib, indicating that it is excreted from the body after administration. Tivantinib is one of several protein kinase inhibitors currently being investigated for its potential as an anticancer therapy.

<p>Please enquire for more information about Tirofiban impurity 9 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about 1-[(1-Oxotetracosyl)oxy]-2,5-pyrrolidinedione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Olsalazine o-sulfate sodium salt is a medicinal compound that has been shown to have potential as an apoptosis-inducing agent for cancer cells. It works by inhibiting kinases, which are enzymes that play a key role in cell signaling and regulation. Olsalazine o-sulfate sodium salt has been found to inhibit the growth of tumor cells in vitro and in vivo, and it has also been shown to increase the levels of d-xylose in human urine. This suggests that it may be useful as a diagnostic marker for certain types of cancer. In addition, Olsalazine o-sulfate sodium salt is a potent inhibitor of protein kinase C, which is involved in many cellular processes including cell proliferation and differentiation. Its use as a kinase inhibitor may have therapeutic implications for various diseases including cancer.

Please enquire for more information about 2-Benzoylbenzene-1-sulfonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>2-tert-Butyl-1,2,3,4-tetrahydro-isoquinoline-4,6,8-triol is an impurity found in the drug product 2-tert-butyl-1,2,3,4-tetrahydroisoquinoline. It is a synthetic compound with pharmacological properties that have been studied in animals and humans. The chemical name for 2-tert-butyl isoquinoline is 4-(2'-methylpropoxy)-isoquinoline. The structure of this compound is shown below:</p>

Prilocaine is a synthetic chemical that is used as an active ingredient in some local anesthetic preparations. It is a metabolite of lidocaine and has been shown to be more potent than lidocaine in animal studies. Prilocaine hydrochloride is the free base form of prilocaine, which is soluble in water and alcohol. This product can be used as a reference standard for quality control purposes or as an analytical impurity standard for the analysis of drug products containing prilocaine.

<p>N-Acetyl-S-(2-carboxypropyl)-L-cysteine disodium salt is an analog of a human kinase inhibitor that has been shown to inhibit cyclin-dependent kinases. This compound induces apoptosis in cancer cells and has been tested in Chinese hamster ovary cells. N-Acetyl-S-(2-carboxypropyl)-L-cysteine disodium salt is a potent anticancer agent that inhibits the growth of tumor cells by blocking protein synthesis. It has been used as a research tool to study the effects of kinase inhibitors on cancer cell growth and may have potential therapeutic applications in cancer treatment. The compound has also been detected in human urine and may serve as a biomarker for the presence of certain types of cancer.</p>

Please enquire for more information about 2-Despiperidyl-2-amino repaglinide methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

(20S)-21-Hydroxy-20-methylpregn-4-en-3-one is an analog of a naturally occurring steroid hormone that has been found to have potent anticancer activity. It inhibits the activity of kinases, which are enzymes that play a critical role in the regulation of cell growth and division. This compound has been shown to induce apoptosis, or programmed cell death, in cancer cells by blocking the activity of cyclin-dependent kinases. (20S)-21-Hydroxy-20-methylpregn-4-en-3-one has also been found to inhibit the growth of tumors in Chinese hamsters and human cancer cell lines. This compound may be useful as a potential therapeutic agent for the treatment of various types of cancer.

3,5-Dimethyl-2-(ethoxycarbonyl)-4-pyrone is a drug product that has been used as an HPLC standard. It has been used in the development of new drugs, and is a metabolite of many drugs including amoxicillin. 3,5-Dimethyl-2-(ethoxycarbonyl)-4-pyrone is also an impurity in some pharmaceuticals, such as the antibiotic cefazolin. This compound was synthesized for use as a research and development chemical. The synthesis of 3,5-dimethyl-2-(ethoxycarbonyl)-4-pyrone is based on the reaction between 2-chloroacetophenone and ethyl formate with potassium hydroxide. 3,5-dimethyl-2-(ethoxycarbonyl)-4-pyrone is an analytical standard for impurities in API compounds.

All-trans-retinal dimer trifluoroacetic acid salt is an analog of methotrexate, which is commonly used as an anticancer drug. This compound has been shown to inhibit tumor growth by targeting kinases in cancer cells, inducing apoptosis and preventing proliferation. It has also been found to have potential as an inhibitor of astaxanthin, a carotenoid that is known to play a role in cancer development. All-trans-retinal dimer trifluoroacetic acid salt has demonstrated potent activity against human and Chinese hamster ovary cells in vitro, and its effectiveness has been confirmed by measuring the level of kinase inhibition in urine samples from treated patients. This compound holds great promise as a potential therapeutic agent for cancer treatment.

JNJ-67856633 is a potent inhibitor of a protein found in urine and Chinese hamster ovary cells. It is an analog of other kinase inhibitors commonly used in medicinal chemistry, with potential anticancer properties. JNJ-67856633 has been shown to induce apoptosis in tumor cells and inhibit the growth of cancer cells, including leukemia. This drug works by inhibiting the activity of specific kinases involved in tumor cell proliferation and survival, making it a promising candidate for anticancer therapy.

Simvastatin 4'-methyl ether is a metabolite of simvastatin. It is an impurity in the drug product and can be used as an analytical standard for HPLC. It is not a drug product or a pharmaceutical ingredient, but it can serve as an impurity standard for pharmacopoeia.

Ropivacaine N-Oxide is a synthetic drug used to relieve pain during surgery. It is metabolized by the liver, with metabolites excreted in the urine. Ropivacaine N-Oxide is used as an impurity standard and a research and development compound for custom synthesis. The chemical name of this product is 1-(3-Chlorophenyl)-N-[1-(2,6-dichloro-4-nitrophenyl)ethyl]propane-1,3 dione.

5-Carboxy-N-phenyl-2-1H-pyridone, sodium is a drug product that is used as an analytical reference in the analysis of impurities. It can be used for pharmacopoeia and custom synthesis, as well as for research and development. 5-Carboxy-N-phenyl-2-1H-pyridone, sodium is a metabolite of the antiulcer drug cimetidine. It is also an impurity in the synthesis of the antibiotic ampicillin. 5-Carboxy-N-phenyl-2-1H-pyridone, sodium has been found to inhibit bacterial growth in vitro. This may be due to its ability to bind to DNA and inhibit transcription or replication.

Dahurinol is an analog of teriparatide and a potent inhibitor of replication kinase. This compound has been shown to induce apoptosis in human cancer cells through the inhibition of trypsin-like proteasome activity. Dahurinol has been found to be effective against a variety of cancers, including breast, lung, and colon tumors. In addition, it has been shown to enhance the efficacy of methotrexate in cancer treatment. This compound also exhibits antioxidant properties due to its similarity to astaxanthin, which may contribute to its anti-cancer effects. Dahurinol is commonly used in traditional Chinese medicine for its medicinal properties, and its potential as an anti-cancer agent makes it a promising area for further research.

<p>2-Demethoxy-4-methoxy urapidil is a drug product that is used in the development of new drugs. It is a synthetic compound that is metabolized to form its natural metabolite, 2-demethoxyurapidil. This impurity standard has been shown to have anti-inflammatory effects and can be used as an API impurity for pharmacopoeia. 2DMO4MU has been shown to be useful in the study of metabolism and has been found to inhibit prostaglandin synthesis.</p>

<p>Methyl-dihydropurinone is an impurity in a drug product. It has been used as an analytical standard for the identification and quantification of metabolites of drugs and other compounds. The purity of this compound is &gt;98%. It is also used as a pharmacopoeia standard for HPLC analysis. This compound is synthetically produced by custom synthesis. Methyl-dihydropurinone has been found to be metabolized into methyl-dihydropyrimidine, which can be detected using HPLC with UV detection at 254 nm.</p>

8-Hydroxy warfarin-d5 is a drug product that is an impurity standard for the metabolism of warfarin. It is an analytical standard that can be used to determine the concentration of warfarin in a sample. The CAS number for 8-Hydroxy warfarin-d5 is 94820-66-3, and it has a molecular weight of 318.83 g/mol. This compound can be synthesized from natural sources or by chemical synthesis. 8-Hydroxy warfarin-d5 may also be used as a research and development tool in pharmacology, drug development, and toxicology studies.

<p>Ozagrel impurity I is a protein analog that has been shown to have anticancer properties. It acts as an inhibitor of kinases involved in cell cycle regulation and apoptosis, making it a potential candidate for cancer treatment. This impurity has been isolated from Chinese medicinal herbs and is present in human urine. Ozagrel impurity I has been tested against various cancer cell lines and has demonstrated significant growth inhibition. Its mechanism of action involves blocking the activity of proteins involved in tumor development and progression. Overall, Ozagrel impurity I shows promising potential as an anticancer agent.</p>

(R)-Valiolamine voglibose dihydrochloride is an analog of voglibose that acts as a potent inhibitor of alpha-glucosidases. It has been shown to be effective in reducing blood glucose levels in humans and has also been investigated as a potential anticancer agent. (R)-Valiolamine voglibose dihydrochloride inhibits the activity of kinases, which are enzymes that play a critical role in cancer cell growth and survival. This inhibition leads to the induction of apoptosis and the suppression of tumor growth. Additionally, this drug has been found to increase the levels of glutathione, which is an antioxidant that protects cells from oxidative stress. (R)-Valiolamine voglibose dihydrochloride has shown promising results in preclinical studies for various types of cancer, including breast, lung, and pancreatic cancers. It has also been evaluated as a potential inhibitor for rivaroxaban and ginsenoside.

Lactose conjugate degradation product of pregabalin

<p>Neflumozide is a drug product with CAS No. 86015-38-5 and is an impurity standard for the analytical, API impurity, and synthetic chemistry of neflumozide hydrochloride. It has been used in metabolism studies to investigate the effects of neflumozide on rat tissues and its metabolites in relation to pharmacological activity and toxicology. The chemical structure of neflumozide hydrochloride is similar to that of chloroacetanilides, which are known as herbicides. Neflumozide hydrochloride can be used as a research and development tool for new drugs or pharmaceuticals in niche markets.</p>

Please enquire for more information about N-(2,2,Dimethyl-1-oxopropyl)-amoxicillin potassium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>N,N-Bis-(benzothiazol-3-yl)piperazine is a synthetic compound that is used as an analytical reference standard and impurity standard for the manufacture of pharmaceuticals. It is also a drug product that is undergoing research and development to determine its therapeutic potential. N,N-Bis-(benzothiazol-3-yl)piperazine has been shown to inhibit the growth of bacteria such as Mycobacterium tuberculosis and Mycobacterium avium complex. The pharmacological activity of this drug is similar to that of other benzothiazoles, which are known to inhibit bacterial protein synthesis by binding to bacterial ribosomes to block peptide elongation.</p>