APIs pour la recherche et les impuretés

Applications 2,2'-AZOBIS-(2-METHYLBUTYRONITRILE) (cas# 13472-08-7) is a useful research chemical.
Dangerous Goods Info This compound is forbidden to ship by air under IATA regulations.

Rac-N-Demethylpromethazine hydrochloride is a racemic mixture of promethazine. It is an analytical reference material that is offered as a high purity API impurity standard, which can be used for HPLC analysis. Rac-N-Demethylpromethazine hydrochloride is also offered as a drug development and drug product impurity standard for the manufacture of drugs. The racemic mixture of promethazine has been shown to inhibit the growth of bacteria by competitive inhibition of bacterial enzymes. Rac-N-Demethylpromethazine hydrochloride acts on bacterial DNA gyrase and topoisomerase IV, which maintain the integrity of bacterial DNA by inhibiting the production of proteins vital for cell division. Rac-N-Demethylpromethazine hydrochloride has also been shown to have antiinflammatory properties in animal studies.

Atropine impurity D is a drug product that is an analytical standard for the metabolism studies of atropine. It is a natural API that belongs to the group of drugs and has CAS number 72-48-0. This drug has been synthesized from the synthetic process and then purified by HPLC. The purity of this drug exceeds 99%. Atropine impurity D is used as an impurity standard in pharmacopoeia, research and development, and drug development.

10,11-Dihydroxy-d10 Carbamazepine is a drug product that is used as an analytical reference standard. It is natural and synthetic impurity in the API (active pharmaceutical ingredient) Carbamazepine. The CAS number for 10,11-Dihydroxy-d10 Carbamazepine is 513-81-5. This compound has been synthesized by custom synthesis and is an impurity standard for HPLC analysis of carbamazepine. 10,11-Dihydroxy-d10 Carbamazepine is also a research and development chemical for the drug development industry. It has been classified as a niche chemical due to its high purity and pharmacopoeia grade.

Tacrolimus is a macrolide that is used as an immunosuppressive drug. It has been shown to bind to the FK-binding protein, which in turn inhibits calcineurin. This prevents the release of IL-2, TNF-α and other cytokines. The immunosuppressive effects of tacrolimus have been evaluated using analytical methods such as coefficients, affinity, and monitoring techniques such as immunoassays and agglutination. These techniques are used to evaluate the plasma concentration of tacrolimus. Tacrolimus also binds to proteins in the blood samples and can be detected by turbidimetric or electrochemiluminescence immunoassay reagents.

Olmesartan medoxomil is a prodrug that is hydrolyzed to olmesartan, its active form. It is a member of the angiotensin II receptor antagonists and it is used for the treatment of hypertension and heart failure. Olmesartan medoxomil reduces the risk of cardiovascular events in patients with resistant hypertension or heart failure. The drug binds to the angiotensin II type 1 receptor, thereby blocking the binding of angiotensin II to this receptor. This prevents activation of downstream signaling pathways, including phospholipase C, protein kinase C, and mitogen-activated protein kinases. Olmesartan medoxomil also blocks the formation of new blood vessels and vascular remodeling in animal models.

Ethyl 3-aminopyrazole-4-carboxylate is an anticancer drug that inhibits the growth of cancer cells by inhibiting protein synthesis. It has been shown to inhibit the activity of dpp-iv and pde5, which are enzymes involved in cellular proliferation. Ethyl 3-aminopyrazole-4-carboxylate has also been shown to have antiinflammatory properties, which may be due to inhibition of prostaglandin synthesis.
Ethyl 3-aminopyrazole-4-carboxylate is a multinuclear compound that reacts with nitrogen atoms from the pyrazoles to form a stable molecule. Dimethylformamide is used as a solvent for this reaction. The synthesis of ethyl 3-aminopyrazole-4-carboxylate starts with acetylation, which converts the carboxylic acid group into an acetic acid group. The acetic acid group reacts with ammonia and hydrogen cyan

6-Methylene progesterone acetate is a polymerase chain inhibitor that inhibits the synthesis of viral and cellular DNA. It was first isolated from infected cells in tissue culture and has been shown to inhibit the growth of a wide range of viruses, including rabies, herpes simplex, herpes zoster, cytomegalovirus, varicella-zoster virus, and vesicular stomatitis virus. 6MPAA also blocks the production of gene products in mammalian cells by preventing RNA synthesis. This drug can be used as an antiviral agent for treatment of enteritis caused by rotavirus infection. 6MPAA binds to gp2 protein on the surface of virus particles and prevents this protein from interacting with polyclonal antibodies or monoclonal antibodies to prevent antibody response.

Dehydroxy bisoprolol is an impurity of the drug Bisoprolol that is used to make the drug product Metoprolol. It is a metabolite of Bisoprolol, which is produced by the liver after metabolism and excretion. Dehydroxy bisoprolol has been detected in plasma, urine, feces, and breast milk. The pharmacological effects of Dehydroxy bisoprolol have not been studied.

Atorvastatin epoxydione impurity (EPI) is a heptanoic, hydrate, diastereoisomer, racemic mixture, enantiomer and impurity of Atorvastatin. The EPI has been minimized in the formulation process by using a novel synthesis route that employs a chiral pyrrole derivative as an intermediate. This minimization has allowed for the elimination of the tautomer and other impurities present in the original compound.

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Isoribavirin is a ribonucleoside monophosphate analog that inhibits viral RNA polymerase. Isoribavirin has been shown to be active against influenza virus, herpes simplex virus, and vesicular stomatitis virus in cell culture. Isoribavirin is stable in an acetonitrile solution in the presence of phosphoric acid at pH 3-4 or in the presence of sulfate ions at pH 9-10. It can be purified by chromatography on a silica gel column using an acetonitrile/water mobile phase gradient. The impurities of isoribavirin are not detectable by liquid chromatography and have no significant effect on its sensitivity. Isoribavirin elutes from the silica gel column with the impurities.

2-Phenylbutyric acid is a product of the oxidation of phenylacetic acid by flavus. 2-Phenylbutyric acid is an inhibitor of contactor reactions that use α1-acid glycoprotein as a chromatographic support. It has been shown to inhibit the reaction mechanism of extractants (e.g., butamirate citrate) with enantiomeric compounds (e.g., creatine). It also inhibits subclinical mastitis in cows and fatty acid synthesis, leading to decreased cholesterol synthesis in humans.

N-(5-Aminopentyl) methotrexate amide is a fluorescent probe that is used to study the transport of drugs across cell membranes. It binds to the plasma membrane of cells and can be visualized with a fluorescence microscope. N-(5-Aminopentyl) methotrexate amide has been shown to bind to leukemia cells in murine leukemia models. It has a high affinity for drug-resistant cells, which makes it useful for studying drug resistance mechanisms. This probe can be used at nanomolar concentrations for imaging studies, as well as for measuring the uptake of drugs into cancer cells by flow cytometry.

Trazodone hydrochloride impurity H is an impurity of the drug product Trazodone hydrochloride. It is a natural metabolite of Trazodone hydrochloride, which is synthesized in vivo by oxidation of the parent compound. Impurity H has been identified as a potential impurity standard for HPLC-UV analysis of Trazodone hydrochloride. The purity of this compound is 98.3% and it is available on a custom synthesis basis.

5-Aminolevulinic acid methyl ester hydrochloride is a drug that is used to treat skin conditions such as psoriasis, dermatitis, and vitiligo. It is used to treat skin cancer and inflammatory diseases such as lupus erythematosus. 5-Aminolevulinic acid methyl ester hydrochloride works by targeting the mitochondria of skin cells. This drug causes mitochondrial membrane depolarization in vitro. The clinical response to this drug is variable and may depend on the severity of the condition being treated. In vivo studies with human subjects show low bioavailability for this drug.

Trazodone is a psychotropic agent that belongs to the group of antidepressants. Trazodone hydrochloride impurity C is a metabolite of trazodone and can be used as an impurity standard for the drug product in pharmacopoeia. Trazodone hydrochloride impurity C has been found in urine, blood, and saliva after administration of trazodone. It is also found in the plasma of pregnant women who are taking trazodone to treat depression or anxiety during pregnancy.
Trazodone hydrochloride impurity C is synthesized using a custom synthesis with high purity. It has been shown to have a niche market as an analytical reference material for HPLC standards.

This compound is a research and development impurity standard. It is synthesized in accordance with the pharmacopoeia, and it is an API impurity. It is also used as a metabolite standard for drug development and metabolism studies. This compound has been tested in HPLC standards.

Natriuretic hormone; induces uterine contraction and lactation

2-Carboxybenzoyl amlodipine is a metabolite of the antihypertensive drug amlodipine. It is a white crystalline solid that is soluble in water. 2-Carboxybenzoyl amlodipine can be used as an impurity standard for HPLC analyses, and as an analytical standard for the determination of amlodipine in human plasma.

Trazodone Hydrochloride Impurity G is a synthetic compound that is an impurity found in Trazodone Hydrochloride, CAS No. 77893-17-6. This compound has the following physical properties: MW = 284.27, mp = 227-229°C, [α] D = -33.5° (c 1.0 in water), and UV max (λ max ) = 228 nm. It has been shown that this compound is not metabolized by human enzymes and is found to be natural. It can be used as a standard for HPLC analysis of Trazodone Hydrochloride Impurities A-F with the following retention times: 8.7 min for Impurity A, 9.2 min for Impurity B, 9.9 min for Impurity C, 10.4 min for Impurity D, 11.1 min for Impurity E, and 12.3 min for Impurity F.BR>BR