APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.440 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.465 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.388 produits)
- Esters et Dérivés(42.306 produits)
- Acides Gras et Dérivés Lipidiques(32.487 produits)
- Flavonoïdes et Polyphénols(17.101 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(214 produits)
- Cétones et Dérivés(2.692 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.410 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.492 produits)
- Phosphates et Phosphonates Organiques(1.205 produits)
- Sulfonates et Sulfates Organiques(10.451 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.340 produits)
- Peptides et Protéines(3.163 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.975 produits)
- Dérivés de Quinazoline et de Quinoléine(66.222 produits)
- Quinones et Dérivés(24.379 produits)
- Sels et Dérivés d’API(92.956 produits)
- Stéroïdes et Dérivés(4.987 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.860 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(231 produits)
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66881 produits trouvés pour "APIs pour la recherche et les impuretés"
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5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide
CAS :5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide is an ammonium salt of a sulfoxide with a chloride. It is also known as esomeprazole magnesium. This drug is used in the preparation of pharmaceutical preparations and is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions. The magnesium salt form is a polymorphic substance that has a crystalline form that occurs in nature, called alpha form, and a synthetic form that occurs in laboratory experiments and has been designated beta form. The alpha form exhibits enantioselectivity when it binds to the enzyme pepsin, which causes the drug to have an antiulcer effect.Formule :C17H19N3O4SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :361.42 g/mol3-O-Desmethyl amlodipine
CAS :3-O-Desmethyl amlodipine is a metabolite of the drug amlodipine. It has been shown to be formed in vivo and may contribute to the pharmacological activity of amlodipine, although its contribution is not well understood. 3-O-Desmethyl amlodipine has been used as an analytical standard for chemical purity testing of pharmaceuticals, and as an impurity standard for HPLC analysis.Formule :C19H23ClN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :394.85 g/molα-Methyl-1,3-benzodioxole-5-propanamine
CAS :Produit contrôléα-Methyl-1,3-benzodioxole-5-propanamine (AMEB) is a chemical compound that minimizes the reaction products in industrial reactions. It has been used as an absorption agent and crosslinking agent in bioconjugate chemistry. The hydroxyl group on AMEB can be removed by hydrolysis to yield α-methyl-1,3-benzodioxole, which can then be converted to the amino acid methionine. AMEB has also been shown to have locomotor activity and to increase the synthesis of hyaluronic acid, which is important for maintaining joint health.
Formule :C11H15NO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :193.24 g/moltrans-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
CAS :The compound is a natural product and its structure is similar to that of the neurotransmitter dopamine. The compound has been used in pharmacological studies as a tool for understanding the neurotoxicity of dopamine and other drugs. This drug has also been used to investigate the level of dopamine receptor occupancy by various dopaminergic drugs.Formule :C13H18FNODegré de pureté :Min. 95%Masse moléculaire :223.29 g/mol(RS)-Di-(2-methoxyethyl) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
CAS :(RS)-Di-(2-methoxyethyl) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is an impurity standard for the API (Active Pharmaceutical Ingredient) Impurity Standard. It may be used as a reference compound in HPLC analyses of analytical samples. This compound has been evaluated by the National Institute of Standards and Technology (NIST) to be a niche HPLC standard. It is also a metabolite of the drug product Metaxalone.Formule :C21H26N2O8Degré de pureté :Min. 95%Couleur et forme :Slightly Yellow PowderMasse moléculaire :434.44 g/mol2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
CAS :2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is a synthetic building block which can undergo reaction with nucleophilic carbon species to afford C-ribosides (via the corresponding hemiacetal). Treatment of 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone with stronger reducing agents, such as sodium borohydride, affords ring opened products with a stereo-defined poly-oxygenated carbon chain backbone.Formule :C26H26O5Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :418.48 g/mol(3S,5S)-Atorvastatin sodium salt
CAS :Atorvastatin is a statin drug that inhibits the enzyme HMG-CoA reductase, which is responsible for cholesterol synthesis. Atorvastatin is used to lower LDL cholesterol and total cholesterol levels in the blood. It also lowers triglyceride levels and raises HDL cholesterol levels. Atorvastatin has been shown to inhibit fibrinogen production, reduce TNF-α production, and improve body mass index (BMI) in obese patients. This drug has been shown to be effective in reducing the size of atherosclerotic lesions by decreasing the amount of cholesteryl esters transferred from high-density lipoprotein (HDL) to low-density lipoprotein (LDL). It has also been shown to inhibit collagen production and stimulate muscle cell proliferation.Formule :C33H34FN2NaO5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :580.62 g/mol(S)-Duloxetine succinamide
CAS :Duloxetine succinamide is a chromatographic, solid, acidic compound. It has been synthesized by reacting (S)-duloxetine hydrochloride with succinic anhydride in the presence of triethylamine and acetonitrile. The reaction mixture was purified by high-performance liquid chromatography to produce the desired product. The purity of the compound was confirmed by postulating that it should have a reversed-phase HPLC profile similar to that of duloxetine succinate. Duloxetine succinamide is not soluble in water and is insoluble in organic solvents such as acetone, chloroform, ether, or benzene. The compound is stable at room temperature but decomposes when heated at higher temperatures. !--Formule :C22H23NO4SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :397.49 g/molN-[1-(R)-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamide
CAS :N-[1-(R)-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamide is an impurity standard that is used in the manufacture of a drug product. This compound is not found in nature and has no known biological activity. It has been shown to be metabolized by CYP2D6, CYP2C8, and CYP2C9. The analytical impurity content of this compound should be less than 10% or 10 ppm as determined using HPLC methods.Formule :C22H20F3NODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :371.4 g/mol(R)-3-(3-Fluoro-4-morpholin-4-ylphenyl)-2-oxo-5-oxazolidinyl)methyl methansulfonate
CAS :(R)-3-(3-Fluoro-4-morpholin-4-ylphenyl)-2-oxo-5-oxazolidinyl)methyl methansulfonate is a Custom synthesis, drug product, Metabolite, Synthetic, Drug development, Impurity standard, Metabolism studies, API impurity, Natural, pharmacopoeia, analytical and HPLC standard. It is CAS No. 174649-09-3.Formule :C15H19FN2O6SDegré de pureté :Min. 95%Masse moléculaire :374.39 g/molOlanzapine ketolactam
CAS :Olanzapine Ketolactam is a drug product that can be custom synthesized. It has a purity of at least 98% and is identified by its CAS number, 1017241-34-7. The metabolite of Olanzapine ketolactam is olanzapine N-oxide, which can be found in the urine of patients who have taken Olanzapine ketolactam. Metabolism studies have been conducted on this drug product to determine how it may affect the body. This drug product is also used in natural or synthetic drug development, pharmacopoeia, and analytical research.
Formule :C17H20N4O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :312.37 g/mol4-(2-Methoxyethyl)phenol
CAS :4-(2-Methoxyethyl)phenol is a synthetic compound that is an antihypertensive agent. It is used to reduce high blood pressure, which may be due to its ability to block the action of angiotensin II, a potent vasoconstrictive hormone, by binding with its receptor. 4-(2-Methoxyethyl)phenol has been shown to be more potent than metoprolol succinate and less toxic than hydroxylated compounds such as propranolol in pharmacokinetic studies. In addition, 4-(2-Methoxyethyl)phenol has been found to have a low risk of congestive heart failure. The industrial process for this substance involves the reaction of hydrochloric acid with phenol in the presence of a catalyst such as aluminium chloride or zinc chloride.
Formule :C9H12O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :152.19 g/mol5,6-Dichloro-1,4-dihydro-2-quinazolinamine
CAS :5,6-Dichloro-1,4-dihydro-2-quinazolinamine (5,6-DCQ) is a small molecule that has been used in vitro to study postnatal development. 5,6-DCQ binds to magnesium and forms a cation complex. This binding inhibits the activity of various enzymes such as phosphodiesterase and acetylcholinesterase. 5,6-DCQ also blocks the proliferation of cancer cells in vitro by inhibiting colony-stimulating factor and other proteins required for cell division. 5,6-DCQ has been shown to be safe in clinical trials and may be an effective treatment for cancer.Formule :C8H7Cl2N3Degré de pureté :Min. 95%Masse moléculaire :216.07 g/mol1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid methyl ester
CAS :Intermediate in the synthesis of ribavirinFormule :C9H13N3O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :259.22 g/molN-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide sodium salt
CAS :2-Nitroacetamide sodium salt is an impurity of the drug N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide, a synthetic chemotherapeutic agent for the treatment of cancers. This compound has been shown to have metabolism studies and natural properties. It has a CAS number of 112251-56-6 and is found in the pharmacopoeia. 2-Nitroacetamide sodium salt is a custom synthesis that can be used as a reference standard for HPLC analysis. It can also be used as a drug product or metabolite in drug development.
Formule :C12H18N3O4SNaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :323.34 g/molN-Cyano-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylsulphinyl]ethyl]guanidine
CAS :N-Cyano-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylsulphinyl]ethyl]guanidine is an acetylcholinesterase inhibitor that is used to treat Alzheimer's disease. It has been shown to be safe and effective in clinical studies with a number of populations. The drug binds to the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine. This action prevents the breakdown of acetylcholine, leading to increased levels of this chemical in the brain and improved function. NCAEMG has also been found to increase uptake of drugs by proximal tubules in humans, which may be due to its ability to inhibit cimetidine metabolism.Formule :C10H16N6OSDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :268.34 g/mol(5α)-17-(3-Pyridinyl)androst-16-en-3-one
CAS :Produit contrôlé(5α)-17-(3-Pyridinyl)androst-16-en-3-one is a natural metabolite of testosterone that is produced in the liver. It has been identified as an impurity in API, which can be found in drugs used for the treatment of high blood pressure and prostate cancer. (5α)-17-(3-Pyridinyl)androst-16-en-3-one is not active as a drug itself, but it can be used as a standard to study the metabolism of testosterone and other steroids.Formule :C24H31NODegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :349.51 g/mol2-(4-Butylphenyl)propionic acid, racemic
CAS :2-(4-Butylphenyl)propionic acid (p-butylhydratropic acid) is a known impurity of ibuprofen (Ibuprofen impurity B) which derives from an impurity present in the isobutylbenzene starting material and 2-(4-butylphenyl)propionic acid. p-Butylhydratropic acid is therefore used as a reference analytical standard.Formule :C13H18O2Degré de pureté :Min. 95%Couleur et forme :Colorless PowderMasse moléculaire :206.28 g/mol3-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid
CAS :3-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid is a chemical compound that is an impurity standard for HPLC. It is also used as a pharmacopoeia, drug development, and analytical reference standard. The CAS number for this compound is 66364-71-4. This compound has been shown to be metabolized by microsomal oxidation, glucuronidation, or sulfation pathways in humans. 3-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid can also be found in natural sources such as plants and animals.Formule :C18H14N4O5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :398.39 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS :5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.Formule :C16H17N3O2SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :315.39 g/mol
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