APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.440 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.464 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.388 produits)
- Esters et Dérivés(42.306 produits)
- Acides Gras et Dérivés Lipidiques(32.486 produits)
- Flavonoïdes et Polyphénols(17.100 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(214 produits)
- Cétones et Dérivés(2.692 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.409 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.492 produits)
- Phosphates et Phosphonates Organiques(1.205 produits)
- Sulfonates et Sulfates Organiques(10.451 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.340 produits)
- Peptides et Protéines(3.164 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.975 produits)
- Dérivés de Quinazoline et de Quinoléine(66.222 produits)
- Quinones et Dérivés(24.379 produits)
- Sels et Dérivés d’API(92.942 produits)
- Stéroïdes et Dérivés(4.987 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.860 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(231 produits)
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66875 produits trouvés pour "APIs pour la recherche et les impuretés"
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Dihydroergotamine mesylate impurity C
Dihydroergotamine mesylate impurity C is an analytical standard used for the determination of purity in Dihydroergotamine Mesylate drug products. The impurity is a metabolite that has been shown to be pharmacologically active and thus should not exceed the limit of detection.Formule :C33H37N5O6Degré de pureté :Min. 95%Masse moléculaire :599.68 g/molTrimethoxy dobutamine hydrochloride
CAS :Trimethoxy dobutamine hydrochloride is a custom synthesis with CAS No. 51062-14-7, drug product and Metabolite. It is developed for niche, Drug development and Natural. Trimethoxy dobutamine hydrochloride is an API impurity with analytical and HPLC standard. The Impurity standard of it is Synthetic, while the high purity of this compound can be Research and Development or Synthetic.Formule :C21H30ClNO3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :379.92 g/molAceclofenac methyl ester
CAS :Aceclofenac methyl ester is an analgesic that belongs to the arylpropionic acid derivatives. It has been developed for the treatment of acute pain. Aceclofenac methyl ester has a structural formula of CH3CO-O-CH3 and a molecular weight of 164.2 g/mol. Aceclofenac is metabolized by CYP450 enzymes, which are located in the liver and other organs, to form acetic acid and 5-hydroxyaceclofenac. The reaction time is approximately 1 hour and tetrahydrofuranyl (THF) is used as a nucleophile in this reaction. This product can be synthesized by reacting ethyl acetate with acetonitrile in high yield, making it stable and anhydrous. The analgesic effects of aceclofenac methyl ester are due to its ability to block the transmission of pain signals from nerves to the brain at the spinal cord levelFormule :C17H15Cl2NO4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :368.21 g/molLercanidipine impurity A
CAS :Lercandipine Impurity A is a metabolite of the drug lercandipine. It is synthesized in the body by oxidation at the benzylic position of the cinnamoyl moiety. This impurity may be present in lercandipine-containing drugs and products, as well as in other drugs and products containing lercandipine. Lercandipine Impurity A has been shown to inhibit the metabolism of lercandipine and may also have anti-inflammatory properties. It is used as an analytical standard for HPLC, pharmacopoeia, drug development, and metabolism studies. Lercandipine Impurity A is found in the following: -Impurities of Lercandipine -Custom synthesis -Lercandipine Drug Product -Synthetic -High purity -Pharmacopoeia -Drug development
Formule :C19H22N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :374.39 g/mol7-epi-Taxol
CAS :Paclitaxel is an anticancer drug that belongs to the class of taxanes. Paclitaxel binds to cell membranes and interferes with cell division by preventing the polymerization of microtubule proteins. This drug can be prepared by high-performance liquid chromatography (HPLC) and has minimal toxicity in humans, but is highly toxic in rats. Paclitaxel also inhibits glucose uptake in breast cancer cells, leading to significant cytotoxicity. It has inhibitory properties against toll-like receptor 4, which may contribute to its anti-inflammatory effects.Formule :C47H51NO14Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :853.91 g/mol3-O-Methyl L-DOPA monohydrate
CAS :Produit contrôlé3-O-Methyl L-DOPA monohydrate is a chromatographic method that is used to diagnose Parkinson's disease. The method separates the catechol-o-methyltransferase (COMT) from plasma samples, which converts dopamine to 3-O-methyl dopamine. The 3-O-methyl dopamine reacts with an electrochemical detector and overlapped peaks can be seen on the chromatogram. This analytical method can be used to detect low levels of dopamine in the blood and diagnose Parkinson's disease.Formule :C10H13NO4·H2ODegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :229.23 g/molD-Asp(9)-Semaglutide
D-Asp(9)-Semaglutide is a semaglutide impurity. The amino acid at position 9 has been replaced by the D-form of the amino acid D-aspartic acid (D-Asp). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.
Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molSemaglutide Impurity 59
D-Arg(28)-Semaglutide is a semaglutide impurity. The amino acid at position 28 has been replaced by the D-form of the amino acid D-arginine (D-Arg). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.
Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molD-Ser32-Tirzepatide
Please enquire for more information about D-Ser32-Tirzepatide including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C225H348N48O68Masse moléculaire :4,813.5 g/mol2-Hydroxy-2-{4-[2-(hydroxyethoxy)ethyl]piperazin-1-yl}dithiazepin
CAS :2-Hydroxy-2-{4-[2-(hydroxyethoxy)ethyl]piperazin-1-yl}dithiazepin (LPSE) is a monoclonal antibody that is used in the diagnosis of atrial fibrillation. It binds to the antigenic determinant on the surface of atrial cells and also has high affinity for cardiac troponin I. LPSE has biochemical properties that distinguish it from other antibodies and is not known to have any adverse reactions or interactions with other drugs. The clinical relevance of LPSE has been demonstrated by its ability to detect atrial cells in tissue samples from patients with atrial fibrillation, and to discriminate between samples taken from patients who had undergone catheter ablation or those who had not undergone this procedure. LPSE binds to tetroxide, gamma-aminobutyric acid (GABA), amides, and proteins, as well as hl-60 cells,Formule :C21H27N3O3SDegré de pureté :Min. 97 Area-%Couleur et forme :Yellow Clear LiquidMasse moléculaire :401.53 g/molBis-[[2-aminoethyl]thio]methane
CAS :Bis-[[2-aminoethyl]thio]methane is a custom synthesis, drug product, niche, Metabolite, Drug development, Natural, pharmacopoeia and API impurity. This chemical is CAS No. 22907-27-3 and has the molecular weight of 249.00 g/mol. It can be synthesized in the laboratory using the following methods: HPLC standard, Research and Development and Impurity standard. The chemical is an analytical standard with a purity of 99%. This chemical can be used as analytical reagent or in research and development of drugs.Formule :C5H14N2S2Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :166.31 g/molMethyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic
CAS :Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate is a particle that is used to treat cardiac arrhythmias. It has been shown to be effective as an antipyretic agent and may also have analgesic properties. Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate is a white powder that melts at temperatures of about 300°C. This drug can be administered by inhalation in the form of a vaporized liquid. The particle size of this drug is typically less than 10 microns in diameter. Methyl 5-benzoyl-2,3-dihydro-1H pyrrolizine 1 carboxylate can be administered through the respiratory tract as an aerosol or nebulizer. The molecular weight of thisFormule :C16H15NO3Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :269.3 g/mol3'-N,N-Didesmethyl-N-(methoxycarbonyl) azithromycin
CAS :3'-N,N-Didesmethyl-N-(methoxycarbonyl) azithromycin is a research and development impurity standard. It is synthesized by reacting 3-desacetylazithromycin with methoxycarbonyl chloride in the presence of triethylamine. This product has been tested for purity by HPLC. CAS No. 16892-65-2Formule :C39H74N2O14Degré de pureté :Min. 95%Masse moléculaire :795.01 g/molPantoprazole sulphone
CAS :Pantoprazole sulphone is a proton-pump inhibitor that inhibits the production of stomach acid and protects the esophagus from damage. Pantoprazole sulphone has been shown to be effective in treating heart disease patients and reducing their risk of death. It also has biological properties, including modulating the effects of bosentan, which is used to treat pulmonary arterial hypertension. Pantoprazole sulphone has been shown to be chemically stable and stereoselective, which means it binds more strongly to one site than another. Clinical pharmacology studies have found that pantoprazole sulphone has no effect on abomasal motility or gastric emptying time.Formule :C16H15F2N3O5SDegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :399.37 g/molN-(2-Amino-4-thiazolyl)acetyl mirabegron
CAS :N-(2-Amino-4-thiazolyl)acetyl mirabegron is a research chemical that belongs to the category of drugs. It is custom synthesized and purified through analytical methods. N-(2-Amino-4-thiazolyl)acetyl mirabegron has been studied for its metabolism in vivo, including its pharmacokinetics and pharmacodynamics. This drug product is a metabolite of mirabegron, an agent used for the treatment of overactive bladder syndrome (OAB). The metabolite is also present in urine and plasma samples.
Formule :C26H28N6O3S2Degré de pureté :Min. 95%Masse moléculaire :536.7 g/molN-Methyl zonisamide
CAS :N-Methyl zonisamide is a drug that is an impurity in Zonisamide. It is an analog of the drug and has been used as a research and development standard for Zonisamide. N-Methyl zonisamide can be synthesized from the corresponding nitrobenzene, aminobenzene, and formaldehyde. The synthesis can be performed by converting nitrobenzene to aminobenzene with sodium hydroxide in methanol, followed by conversion to N-methyl zonisamide with formaldehyde in ethanol. Pharmacopoeia standards for this compound are available from Sigma Aldrich, which can be purchased from our website.Formule :C9H10N2O3SDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :226.25 g/molOlmesartan
CAS :Olmesartan medoxomil is a prodrug that is hydrolyzed to olmesartan, its active form. It is a member of the angiotensin II receptor antagonists and it is used for the treatment of hypertension and heart failure. Olmesartan medoxomil reduces the risk of cardiovascular events in patients with resistant hypertension or heart failure. The drug binds to the angiotensin II type 1 receptor, thereby blocking the binding of angiotensin II to this receptor. This prevents activation of downstream signaling pathways, including phospholipase C, protein kinase C, and mitogen-activated protein kinases. Olmesartan medoxomil also blocks the formation of new blood vessels and vascular remodeling in animal models.
Formule :C24H26N6O3Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :446.5 g/mol2-Acetamido-9-[[2-(acetyloxy)ethoxy]methyl]-6,9-dihydro-1H-purin-6-one
CAS :2-Acetamido-9-[2-(acetyloxy)ethoxy]methyl-6,9-dihydro-1H-purin-6-one (ademetionine) is a prodrug that is metabolized in the liver to form ademetionine. Ademetionine is a potent inhibitor of guanosine deaminase, which is an enzyme that breaks down guanosine into guanine and ammonia. Ademetionine has shown efficacy in cancer treatment and may also be used to treat tuberculosis. The metabolism of this drug takes place in the liver, where it undergoes oxidation by cytochrome P450 enzymes to form the active metabolite ademetionine. Metabolism of this drug can be inhibited by drugs such as trifluoromethanesulfonic acid (TFMS), which are used for the treatment of malaria. TFMS inhibits the formation of ademetionine but does not affect the formationFormule :C12H15N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :309.28 g/molDihydro-α-ergocryptine mesylate
CAS :Dihydro-alpha-ergocryptine mesylate is a drug that inhibits the effects of ergotamine and other drugs. It is used in animals to treat drug reactions, such as those caused by morphine and penicillin. Dihydro-alpha-ergocryptine mesylate can be detected in urine samples for up to 72 hours after administration. The pharmacokinetic properties of this drug are not well understood, but there is a linear relationship between dose and plasma concentration. The clinical response to dihydro-alpha-ergocryptine mesylate has been shown to be dose dependent. This drug also has dopaminergic properties, which may be due to its ability to bind with dopamine receptors in the central nervous system. There are several symptoms that may be related to taking this drug, including drowsiness or fatigue, nausea or vomiting, dry mouth, muscle spasms, and involuntary shaking of a part of the body (tremor).Formule :C33H47N5O8SDegré de pureté :Min. 95%Masse moléculaire :673.82 g/molMemantine impurity IV
CAS :Memantine impurity IV is a hydrolysis product of memantine. It appears as a white to off-white powder and has a molecular weight of 198.1 g/mol. Memantine impurity IV is an intermediate in the production of memantine and is therefore not used for any other purpose. The compound contains hydroxy groups, hydroxy, alcohols, and bridgehead groups which are efficient at hydrolyzing to form amino acids.
Formule :C12H21NO·HClDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :231.76 g/mol
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