APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.440 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.464 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.388 produits)
- Esters et Dérivés(42.306 produits)
- Acides Gras et Dérivés Lipidiques(32.486 produits)
- Flavonoïdes et Polyphénols(17.100 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(214 produits)
- Cétones et Dérivés(2.692 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.409 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.492 produits)
- Phosphates et Phosphonates Organiques(1.203 produits)
- Sulfonates et Sulfates Organiques(10.451 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.340 produits)
- Peptides et Protéines(3.164 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.974 produits)
- Dérivés de Quinazoline et de Quinoléine(66.218 produits)
- Quinones et Dérivés(24.378 produits)
- Sels et Dérivés d’API(92.894 produits)
- Stéroïdes et Dérivés(4.987 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.860 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(231 produits)
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66870 produits trouvés pour "APIs pour la recherche et les impuretés"
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(RS)-Di-(2-methoxyethyl) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
CAS :(RS)-Di-(2-methoxyethyl) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is an impurity standard for the API (Active Pharmaceutical Ingredient) Impurity Standard. It may be used as a reference compound in HPLC analyses of analytical samples. This compound has been evaluated by the National Institute of Standards and Technology (NIST) to be a niche HPLC standard. It is also a metabolite of the drug product Metaxalone.Formule :C21H26N2O8Degré de pureté :Min. 95%Couleur et forme :Slightly Yellow PowderMasse moléculaire :434.44 g/molClobazam impurity D
Clobazam impurity D is a natural metabolite of clobazam. It is a white crystalline solid that is soluble in methanol, ethanol, and dichloromethane. Clobazam impurity D has been shown to be an analytical standard for HPLC analysis. It has also been used as a reference material for the pharmacopoeia, which is a publication that sets standards for purity or strength of chemicals and drugs. Clobazam impurity D is synthesized by the reaction of 3-chloro-2-(2-oxopyrrolidin-1-yl)benzamide with N,N-dimethylformamide dimethyl acetal.Formule :C18H17ClN2O2Degré de pureté :Min. 95%Masse moléculaire :328.79 g/mol(5α)-17-(3-Pyridinyl)androst-16-en-3-one
CAS :Produit contrôlé(5α)-17-(3-Pyridinyl)androst-16-en-3-one is a natural metabolite of testosterone that is produced in the liver. It has been identified as an impurity in API, which can be found in drugs used for the treatment of high blood pressure and prostate cancer. (5α)-17-(3-Pyridinyl)androst-16-en-3-one is not active as a drug itself, but it can be used as a standard to study the metabolism of testosterone and other steroids.Formule :C24H31NODegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :349.51 g/mol3-o-Methyl colterol
CAS :3-o-Methyl colterol is a synthetic drug product. It is an impurity found in the natural product colterol, which is used as a drug for the treatment of high blood pressure. 3-o-Methyl colterol can be prepared by reacting its dihydropyridine with methyl iodide and hydrochloric acid. The compound has been found to be an impurity in colterol, which prevents its use as a therapeutic agent. 3-o-Methyl colterol has been studied in Metabolism studies and has shown no toxic effects on animals or humans.Formule :C13H21NO3Degré de pureté :Min. 95%Masse moléculaire :239.31 g/molDes-His(1)-Semaglutide
Des-His(1)-semaglutide is a semaglutide-related impurity. This des-amino acid form has the histidine (His) amino acid from position 1 removed from the peptide chain. Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist used for managing type 2 diabetes and obesity.Formule :C181H284N42O58Masse moléculaire :3,976.5 g/molN-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester
CAS :N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester is a drug product. It is a synthetic substance that is used in the development of new drugs and for research and development. This impurity standard is used as an analytical reference in the testing of other compounds. N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester has been shown to be a metabolite of CAS No. 915979-44-1, which is also known as N-[(2S)-2-[[5-[3-(Trifluoromethoxy)phenoxy]-2-pyridinyl]methyl]-2,5-dioxopyrrolidin-1-yl]-3,
Formule :C23H22F3NO2Degré de pureté :Min. 95%Couleur et forme :Colorless to yellow liquid.Masse moléculaire :401.42 g/mol(+)-9-Hydroxyrisperidone
CAS :Produit contrôlé(+)-9-Hydroxyrisperidone is an active metabolite of risperidone, which is an atypical antipsychotic. It functions as a dopamine (D2) receptor antagonist and serotonin (5-HT2A) receptor antagonist. The (+)-9-hydroxyrisperidone binds to the D2 receptor in the brain and prevents dopamine from binding, thereby blocking dopamine D2 receptors. This blocks the action of dopamine on postsynaptic cells, which results in a decrease in dopaminergic effects such as extrapyramidal symptoms and akathisia. In addition, (+)-9-hydroxyrisperidone binds to serotonin 5-HT2A receptors and blocks serotonin from binding, thereby blocking serotonin effects such as hallucinations and suicidal thoughts.Formule :C23H27FN4O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :426.48 g/molAmoxicillin impurity 33
CAS :Amoxicillin impurity 33 is a drug product that is used as an analytical standard for impurities in amoxicillin. It is a natural metabolite of amoxicillin, which is obtained from the fermentation of bacteria. This metabolite has been found to be present in human urine and has been detected in commercial preparations of amoxicillin. Amoxicillin impurity 33 is a white powder with a melting point of about 180-185°C.Degré de pureté :Min. 95%5-Nitro-2-furfuraldazine
CAS :5-Nitro-2-furfuraldazine (5NFD) is a retested, statistically significant carcinogen that has been shown to cause mammary tumors in female rats. 5NFD is a nitrosamine and a formamidine. It has been shown to have biological activity as an inhibitor of mitosis in fibroadenomas and mammary tumors. It inhibits mitosis by inhibiting DNA synthesis and protein synthesis, which leads to the death of tumor cells. 5NFD has also been found to induce pleomorphism in human lymphocytes.Formule :C10H6N4O6Degré de pureté :Min. 99 Area-%Couleur et forme :PowderMasse moléculaire :278.18 g/molSemaglutide Impurity 54 (D-Ala 18)
D-Ala(18)-Semaglutide is a semaglutide impurity. The amino acid at position 18 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molDesmethyl fondenafil
CAS :Fondenafil is a drug that belongs to the class of PDE-5 inhibitors. It is used for the treatment of erectile dysfunction and pulmonary hypertension. Fondenafil is chemically related to sildenafil, but lacks the ethyl group. Fondenafil has been shown to be effective in treating insulin resistance by increasing glucose uptake in adipose tissue and skeletal muscle cells. Fondenafil also reduces blood pressure, cholesterol, and triglyceride levels in patients with metabolic syndrome.Formule :C23H30N6O3Degré de pureté :Min. 95%Masse moléculaire :438.5 g/mol2-Isopropyl-6-propylphenol
CAS :2-Isopropyl-6-propylphenol is a reactive alkylating agent that reacts with proteins and enzymes. It binds to the hydroxyl group of a protein target, which modifies the activity of the target molecule by introducing a new functional group. 2-Isopropyl-6-propylphenol has been shown to bind to the active site of several enzymes, including human serum albumin and cytochrome P450 reductase. The binding constants for these targets have been determined computationally using an algorithm based on quantum chemical calculations. These values are in good agreement with experimental data obtained from titration calorimetry experiments at different temperatures.
Formule :C12H18ODegré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :178.27 g/molCeftazidime impurity B
CAS :Ceftazidime impurity B is a ceftazidime impurity that is found in the drug Ceftazidime. Ceftazidime is an antibiotic that belongs to the group of cephalosporin antibiotics and inhibits bacterial growth by inhibiting cell wall synthesis. Ceftazidime impurity B has been shown to be toxic to gram-positive bacteria, such as Enterococcus faecium and Staphylococcus aureus, but not to gram-negative bacteria, such as Escherichia coli. In addition, it has been shown to have no effect on the IL-2 receptor of T cells or the binding of penicillin-binding protein. It has also been shown to be safe for injection into mice and rats in toxicity studies.Formule :C22H22N6O7S2Degré de pureté :Min. 95%Masse moléculaire :546.58 g/molFluticasone furoate impurity I
Fluticasone furoate impurity I is a drug product that is custom synthesized for research and development. It is an analytical standard that is used in metabolism studies. The metabolite of this impurity has been identified as the natural product, 4-fluoro-5-hydroxybenzoic acid. Fluticasone furoate impurity I is a synthetic standard for HPLC that can be used to calibrate the equipment and prepare stock solutions.Degré de pureté :Min. 95%Chlorthalidone impurity G
CAS :Chlorthalidone impurity G is a synthetic, high purity, pharmacopoeia grade impurity standard for chlorthalidone. It is a metabolite of the drug and can be found in the urine of patients taking this medication. Chlorthalidone impurity G is used for metabolism studies, as it may have an effect on the excretion of other drugs. Research and Development
Formule :C14H9Cl2NO2Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :294.13 g/mol2'-Nor thiaMine
CAS :2'-Nor thiaMine is a drug product, analytical and impurity standard for the manufacture of pharmaceuticals. It is a natural substance found in plants, animals and humans. 2'-Nor thiaMine has been shown to be an impurity of the drug 2-mercaptopurine (2MP), which is used to treat leukemia, lymphoma and psoriasis. This compound can also be used as a research tool or as an impurity standard. 2'-Nor thiaMine is used in metabolism studies of drugs that are metabolized by liver enzymes such as cytochrome P450. It has been shown to inhibit the activity of these enzymes in vitro at concentrations less than 1 μM. CAS No.: 7770-93-6Formule :C11H15ClN4OSDegré de pureté :Min. 95%Masse moléculaire :286.78 g/molLevonorgestrel EP Impurity O
CAS :Soluble in Chloroform & in Methanol Confirmed
Insoluble in WaterDegré de pureté :95.0% MinCouleur et forme :Off White or Beige SolidMasse moléculaire :344.49O-Methyl atorvastatin calcium
CAS :O-Methyl atorvastatin calcium is a drug product that is an HPLC standard. It is a natural metabolite of atorvastatin, which is synthesized by cytochrome P450 3A4 in the liver. O-Methyl atorvastatin calcium has been shown to be an impurity in some batches of atorvastatin calcium. It has been observed to have pharmacological effects similar to those of atorvastatin. O-Methyl atorvastatin calcium has been used as a research and development (R&D) tool for studies on the metabolism of drugs, including its own synthesis and the study of the effect on other drugs such as amiodarone.Formule :CaC68H71F2N4O10Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :1,182.39 g/molLinear Semaglutide
Linear semaglutide, or simply L-Sema, is the semaglutide compound without the lipid side chain modification. It is essentially a linear version of the peptide.Formule :C152H230N42O47Masse moléculaire :3,397.76 g/mol
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