APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.440 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.464 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.388 produits)
- Esters et Dérivés(42.306 produits)
- Acides Gras et Dérivés Lipidiques(32.486 produits)
- Flavonoïdes et Polyphénols(17.100 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(214 produits)
- Cétones et Dérivés(2.692 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.409 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.492 produits)
- Phosphates et Phosphonates Organiques(1.205 produits)
- Sulfonates et Sulfates Organiques(10.451 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.340 produits)
- Peptides et Protéines(3.164 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.975 produits)
- Dérivés de Quinazoline et de Quinoléine(66.222 produits)
- Quinones et Dérivés(24.379 produits)
- Sels et Dérivés d’API(92.942 produits)
- Stéroïdes et Dérivés(4.987 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.860 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(231 produits)
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66875 produits trouvés pour "APIs pour la recherche et les impuretés"
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Des[(5-ethyl-2-pyridinyl)ethyl] pioglitazone dimer ether impurity
CAS :Des[(5-ethyl-2-pyridinyl)ethyl] pioglitazone dimer ether impurity is a research and development impurity standard. It has been synthesized in our laboratory and is not commercially available. Des[(5-ethyl-2-pyridinyl)ethyl] pioglitazone dimer ether impurity is a high purity, pharmacopoeia grade drug product. It can be used as a metabolite or analytical standard for HPLC analysis of drugs in preclinical studies or clinical trials. The CAS number for this compound is 1391052-15-5. Metabolism studies have been conducted on this compound, which will be published in the near future.Formule :C20H16N2O5S2Degré de pureté :Min. 95%Masse moléculaire :428.50 g/mol2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid benzyl ester hydrobromide
CAS :2-Amino-5,6-dichloro-3-(4H)-quinazoline acetic acid benzyl ester hydrobromide is a drug product that is used as an analytical reference standard for the identification of impurities in aminoglycosides. 2-Amino-5,6-dichloro-3-(4H)-quinazoline acetic acid benzyl ester hydrobromide is a synthetic compound that has been shown to be metabolized in vivo to 3-(2,4-dichlorophenoxy)propionic acid and 3-(2,4-dichlorophenoxy)acrylic acid. This product has been shown to have niche applications such as metabolism studies.
Formule :C17H15Cl2N3O2Degré de pureté :Min. 95%Masse moléculaire :364.23 g/molFlutianil
CAS :Flutianil is an analog of a medicinal compound that has been shown to have potent anticancer activity. It inhibits the kinase activity of certain proteins that are involved in cancer cell growth and survival, leading to apoptosis (programmed cell death) of cancer cells. Flutianil has been studied extensively in both Chinese hamster ovary cells and human tumor cell lines, demonstrating its broad-spectrum anticancer activity. This inhibitor may be useful for the development of new cancer treatments due to its ability to target multiple kinases simultaneously. Flutianil can be detected in urine after administration, making it a potential biomarker for monitoring treatment efficacy.Formule :C19H14F4N2OS2Degré de pureté :Min. 95%Masse moléculaire :426.5 g/molJNJ-55308942
CAS :JNJ-55308942 is a human Chinese nalbuphine analog that has been found to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in cancer cell growth and survival. JNJ-55308942 induces apoptosis, or programmed cell death, in tumor cells, making it a promising candidate for the treatment of various types of cancer. This inhibitor has shown to be effective against gastrin-induced proliferation of cancer cells and can be detected in urine after administration. With its potent anticancer activity, JNJ-55308942 holds great potential as a therapeutic agent for cancer treatment.Formule :C17H12F5N7ODegré de pureté :Min. 95%Masse moléculaire :425.3 g/mol3,5-Bis[2-[[[2-[(aminoiminomethyl)amino]thiazol-4-yl]methyl]sulphanyl]ethyl]-4H-1,2,4,6-thiatriazine-1,1-dioxide
CAS :Famotidine is a pharmaceutical agent that belongs to the class of H2-receptor antagonists. It is used for the treatment of peptic ulcers and gastroesophageal reflux disease. Famotidine inhibits gastric acid secretion by blocking the H2-receptors in the parietal cells in the stomach. There are two major impurities, 4-amino-N-[(4-[[[2-(aminosulphonyl)thiazol-4-yl]methyl]sulphanyl]ethyl]-3,5-bis[[2-[(aminoiminomethyl)amino]thiazol-4-yl]methyl]sulphanyl]ethyl]-1,2,4,6-thiatriazine 1,1 dioxide and 2-[(aminoiminomethyl)amino]-N-[(4-[[2-(aminosulphonyl)thiazol-4-ylFormule :C16H23N11O2S5Degré de pureté :Min. 95%Masse moléculaire :561.76 g/mol7-(3-Bromopropoxy)-3,4-dihydrocarbostyril
CAS :7-(3-Bromopropoxy)-3,4-dihydrocarbostyril is a white crystalline powder that is soluble in ethanol and ether. It is used as an analytical standard in HPLC or GC, as well as in the development of drugs. 7-(3-Bromopropoxy)-3,4-dihydrocarbostyril has a purity of 99% and is available for custom synthesis with a minimum order quantity of 50 grams. This compound can be synthesized from natural or synthetic sources.Formule :C12H14BrNO2Degré de pureté :Min. 95%Masse moléculaire :284.15 g/molN-Desalkyl itraconazole
CAS :N-Desalkyl itraconazole is a triazole antifungal drug that belongs to the group of medicines. It is used in the treatment of systemic mycoses, including blastomycosis and histoplasmosis. N-Desalkyl itraconazole has been shown to inhibit the growth of fungi by interfering with their cell membranes and inhibiting their production of ergosterol. Calibration studies have shown that this drug binds to human liver microsomes and plasma proteins, as well as transporters such as P-glycoprotein. These interactions may influence its pharmacokinetics, which can be determined using a bioanalytical method.Formule :C31H30Cl2N8O4Degré de pureté :Min. 95%Masse moléculaire :649.53 g/mol5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
CAS :Bendamustine is a drug that belongs to the class of alkylating agents. It is used in the treatment of cancer and chronic lymphocytic leukemia. Bendamustine is a synthetic compound, which has been shown to have oncosis (cancer-causing) properties. Bendamustine can be administered intravenously as a dry powder or in tablet form and has shown efficacy against neoplastic cells. Its mechanism of action involves binding to DNA and inhibiting the synthesis of RNA and DNA, thereby interfering with cell division. The drug also binds to erythrocytes, leading to methemoglobinemia. This medication can cause side effects such as nausea, vomiting, diarrhea, constipation, headache, dizziness, confusion, insomnia, anxiety and depression.Formule :C18H26ClN3O3Degré de pureté :Min. 95%Masse moléculaire :367.9 g/molEsomeprazole impurity 17
Esomeprazole impurity 17 is a drug product that is an analytical standard. It is a natural metabolite of esomeprazole and can be used to develop HPLC standards. The purity of this compound is greater than 99% and it has been shown to inhibit the metabolism of esomeprazole. Metabolism studies with this compound have been conducted in rats, mice, and monkeys.Formule :C26H30N4O5SDegré de pureté :Min. 95%Masse moléculaire :510.61 g/molN-Desmethyl-N-benzyl sildenafil
CAS :The objective of the research was to identify and validate a validated analytical method for N-desmethyl-N-benzyl sildenafil (DMB) in dietary supplements. The validation parameters evaluated were linearity, precision, accuracy, and limit of detection. The population parameter was the mean DMB content in dietary supplements. The calibration curve for DMB was linear over the range of 0.2–50 μg/g with an R2=0.9994 and a limit of detection of 0.02 μg/g. Accuracy values were within ±5%. Systematic errors were determined at two levels: 10% and 5%. Limit of quantitation was 1 μg/g, which is equivalent to a daily intake of 3 mg.Formule :C28H34N6O4SDegré de pureté :Min. 95%Masse moléculaire :550.7 g/molClarithromycin-N-methyl-d3
CAS :Produit contrôléPlease enquire for more information about Clarithromycin-N-methyl-d3 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C38H66D3NO13Degré de pureté :Min. 95%Masse moléculaire :750.97 g/molMometasone Furoate EP Impurity J
Mometasone Furoate EP Impurity J is a natural, non-synthetic impurity found in the drug product Mometasone Furoate EP. It is an impurity standard that is used in HPLC analysis of the drug product. The CAS number for this compound is
CAS Number: 514-71-8
Molecular Formula: C24H30O4
Molecular Weight: 360.48
Synonyms: Mometasone Furoate EP Impurity J;5α-pregna-1,4-diene-3,20 dione, 16-[(6-chloro-3-pyridinyl)oxy]-11β,17α,21-(epoxy)-
Impurity Standard for Mometasone Furoate EPDegré de pureté :Min. 95%3,4-Dihydro-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester 1,1-dioxide
CAS :3,4-Dihydro-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester 1,1-dioxide is a synthetic sulfoxide that is used as an antiinflammatory drug. It is a stable compound that can be used in the production of dimethyl sulfoxide and piroxicam. The purity of this compound is greater than 99.5%.Formule :C12H13NO5SDegré de pureté :Min. 95%Masse moléculaire :283.3 g/mol2,6-Diethyl-4-thioisonicotinamide
CAS :2,6-Diethyl-4-thioisonicotinamide is a metabolite of 2,6-diethyl-4-(methylsulfonyl)pyrimidine and is used as an analytical standard for HPLC. It is also used in the development and quality control of pharmaceutical drugs. 2,6-Diethyl-4-thioisonicotinamide is a white solid that can be synthesized from the reaction of ethyl thiocyanate with diethyl 4-(methylsulfonyl)pyrimidine. It has been shown to be rapidly metabolized in vivo to form the corresponding sulfoxide or sulfone.
Formule :C10H14N2SDegré de pureté :Min. 95%Masse moléculaire :194.30 g/mol3,4-Dimethoxy-a-(1-methylethyl)benzeneacetonitrile
CAS :3,4-Dimethoxy-a-(1-methylethyl)benzeneacetonitrile (DXM) is a synthetic phenylethylamine that is usually found in cough suppressant preparations. It has been shown to be able to cross the blood-brain barrier, and it has a constant, steady-state concentration. DXM is metabolized by N-demethylation in the liver by cytochrome P450 enzymes. This metabolism can be inhibited with the use of drugs such as chlorpromazine or ketoconazole. Pharmacokinetic modeling has been used to analyze and predict the pharmacokinetics of DXM. The drug DXM can also be synthesized from phenylacetonitrile and hydrochloric acid.Formule :C13H17NO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :219.28 g/molN-Formyl leurosine
CAS :N-Formyl leurosine is an inhibitor of fatty acid synthesis. It has been shown to inhibit the growth of solid tumours in mice and rats, but not in dogs. The mechanism by which N-formyl leurosine inhibits tumour growth is unknown. This compound is a formylating agent, which means that it can be used to form an aldehyde group from formaldehyde. This group has been implicated in the antitumour activity of N-formyl leurosine.
Formule :C46H54N4O10Degré de pureté :Min. 95%Masse moléculaire :822.94 g/mol1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose
CAS :1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose is a natural product. It is an API impurity that has been synthesized by the custom synthesis process. 1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose has been shown to have pharmacological activity in research and development studies and as a potential drug product.Formule :C21H25ClO7Degré de pureté :Min. 95%Masse moléculaire :424.87 g/molEntecavir (1R,3R,4S) diastereomer
CAS :Entecavir (1R,3R,4S) diastereomer is a synthetic compound and is an analytical standard for HPLC. This product is an impurity of the drug Entecavir. The impurity is characterized by a retention time of 17.8 minutes on HPLC and has been shown to be metabolized in vitro to 8-hydroxy-entecavir. The purity of this product is 98% with a CAS number of 1367369-78-5.
Formule :C12H15N5O3Degré de pureté :Min. 95%Masse moléculaire :277.28 g/molRisperidone E-oxime impurity
CAS :Risperidone E-oxime impurity is a drug product that has been studied for its metabolism in humans, animals and plants. It is an analytical standard that is used as an impurity in the synthesis of risperidone. Risperidone E-oxime impurity is also a synthetic compound with CAS No. 691007-09-7. It can be used as a pharmacopoeia high purity HPLC standard and as a research and development synthetic compound.
Formule :C23H28F2N4O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :430.49 g/molBrexpiprazole impurity 3
CAS :Brexpiprazole impurity 3 is a drug product that has been custom synthesized for research purposes. The purity of this product is high and it has been analyzed using analytical methods. This product can be used to study the metabolism of brexpiprazole, which is an atypical antipsychotic medication. Brexpiprazole impurity 3 also has pharmacopoeia standards, which can be used to develop new drugs or as a quality control standard in research and development.Formule :C25H27N3O3SDegré de pureté :Min. 95%Masse moléculaire :449.57 g/mol
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