APIs pour la recherche et les impuretés

<p>Acyclovir Impurity O is an impurity found in the drug Acyclovir. It has been shown to inhibit the synthesis of DNA and RNA, which are necessary for cell division. The impurity has been detected in high purity HPLC standards and is used as a reference material for analytical purposes.<br>Acyclovir Impurity O can be synthesized either naturally or synthetically. It is an impurity that is regulated by the USP, BP, and EP pharmacopeias.</p>

<p>Olsalazine sodium impurity A is a synthetic drug that is used as an active pharmaceutical ingredient (API) in the development of drug products. It is a metabolite of olsalazine sodium, which is a natural product. Olsalazine sodium impurity A has been shown to be an analytical impurity for HPLC standards and is also used in metabolism studies. This impurity has niche applications as an analytical standard or as a pharmacopoeia reference material.END&gt;</p>

<p>Hydrocotarnine hydrochloride is a medicinal compound that has been found to have anticancer properties. It is an inhibitor of protein kinases, which are enzymes that play a key role in regulating cell cycle progression and apoptosis. Hydrocotarnine hydrochloride has been shown to induce apoptosis in cancer cells, making it a promising candidate for the development of novel cancer therapies. This compound has also been identified as a potential inhibitor of tumor growth in Chinese medicine. In vitro studies have demonstrated that hydrocotarnine hydrochloride inhibits the proliferation of various cancer cell lines, suggesting its potential as a therapeutic agent for the treatment of cancer.</p>

<p>9α-Fluoro-6α-methylprednisolone 21-acetate is an analog of the hormone cortisol and has potent anti-inflammatory and immunosuppressive properties. It is also being studied for its potential anticancer activity. This compound inhibits cyclin-dependent kinases, which are involved in regulating cell division and growth. It has been shown to induce apoptosis in cancer cells and inhibit tumor growth in animal models. Additionally, it has been found in human urine, indicating that it may have potential as a biomarker for cancer diagnosis or monitoring.</p>

<p>Chlorhexidine digluconate EP Impurity L is a metabolite of chlorhexidine digluconate. It is an impurity found in the drug product, which is used for the treatment of skin and mucous membrane infections. The mechanism of action for chlorhexidine digluconate EP Impurity L is not known. However, it has been shown to be metabolized by CYP3A4 and CYP2C9 enzymes to form chlorhexidine acetate, a metabolite that inhibits bacterial growth, and hydrolyzed by esterases to form 2-hydroxychlorhexidine acetate. This metabolite has been found in the urine of rats following oral administration with chlorhexidine digluconate EP Impurity L.</p>

<p>Trans-4-(6,8-Dibromo-3(4H)-quinazolinyl)cyclohexanol hydrochloride is a potent kinase inhibitor that has shown promising results in anticancer research. It specifically targets human kinases and induces apoptosis in cancer cells. This compound has been identified as a potential therapeutic agent for the treatment of various types of tumors, including those found in breast, lung, and prostate cancers. In addition to its medicinal properties, trans-4-(6,8-Dibromo-3(4H)-quinazolinyl)cyclohexanol hydrochloride can be detected in urine samples and serves as an important tool for researchers studying protein kinases and their inhibitors. This analog of Chinese medicine is a valuable addition to any laboratory seeking to advance cancer research through the development of new therapies.</p>

<p>(S)-2-Amino-3-(3,5-diiodo-4-(4-methoxyphenoxy)phenyl propanoic acid is a synthetic compound that is used as an impurity standard. It has been shown to be metabolized by cytochrome P450 enzyme system and its metabolites are excreted in the urine. This chemical can also act as an analytical reference for HPLC analysis of other compounds.</p>

<p>N2-Methyl alfuzosin hydrochloride (1:1) is a synthetic compound that is used as an impurity standard for the drug product Alfuzosin. It has been shown to be metabolized by the liver, and its metabolites are excreted through the bile. The N2-methyl group of this compound provides a marker for metabolism studies and it has been shown to inhibit bacterial growth in vitro.</p>

<p>Cefixime Impurity A is a drug product that is used for analytical purposes. It is an impurity of cefixime.</p>

<p>Please enquire for more information about NSC 37553 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-O-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl] balsalazide is a drug product that has been custom synthesized and purified to high purity. It is an analytical standard for metabolism studies. This compound is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 2-O-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl] balsalazide is also used as a pharmacopoeia impurity standard and as a research and development HPLC standard.</p>

<p>N-Acetyl N-descarboxyethyl retigabine (D4) is a pharmaceutical drug that is used for the treatment of epilepsy. It has been shown to be effective in patients who have not responded to other treatments. D4 binds to voltage-gated potassium channels and inhibits their opening, which leads to a decrease in neurotransmitter release from nerve cells. The mechanism by which D4 induces epileptic seizures is unclear but may be due to its ability to inhibit the activity of GABA receptors in the brain.</p>

<p>Mikimopine is a kinase inhibitor that has shown promising results in the treatment of cancer. It works by inhibiting specific proteins involved in cancer cell growth and survival, leading to apoptosis (cell death) of tumor cells. Mikimopine is an analog of a naturally occurring protein found in human urine and Chinese medicinal herbs. It specifically targets cyclin-dependent kinases, which are enzymes that regulate cell division and proliferation. This drug has shown potent anticancer activity both in vitro and in vivo, making it a promising candidate for further development as an anticancer agent. Its selectivity towards cancer cells makes it a potentially effective therapy with minimal side effects compared to traditional chemotherapy treatments.</p>

<p>5'-O-Acetyl ribavirin is an impurity of ribavirin, a drug product that belongs to the group of antiviral drugs. It is used in the treatment of chronic hepatitis C and influenza. 5'-O-Acetyl ribavirin is found in natural products such as plants, honey, and wine. The CAS number for this impurity is 58151-87-4. This compound can be synthesized through custom synthesis or by using a high purity HPLC standard as an impurity standard.</p>

<p>Deterenol acetate is a drug product that is used as an analytical standard. It has been shown to be a natural metabolite of the synthetic drug deterenoic acid, which is an impurity in API preparations of the drug. Deterenol acetate has been shown to have anti-inflammatory effects and may be useful for treating cardiovascular disease, cancer, and arthritis. Deterenol acetate has also been shown to have potential as a treatment for high blood pressure.</p>

<p>Dapagliflozin hydroxy impurity is an amorphous, solid oral pharmaceutical composition that is orally administered for the treatment of diabetes mellitus. Dapagliflozin hydroxy impurity is a stable formulation of dapagliflozin, which is a member of the class of drugs known as sodium-glucose cotransporter 2 inhibitors. Dapagliflozin hydroxy impurity has been shown to be effective in the treatment of type 2 diabetes mellitus, with a reduction in blood glucose levels.</p>

<p>(E)-4-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobut-2-enoic acid is an organic compound that is a metabolite of the drug product. It is a synthetic chemical compound and does not occur in nature. It has been used as an analytical standard for HPLC and LC/MS. It has also been used as an impurity standard for API's. This product is typically produced synthetically, but can be obtained through metabolism studies with niche organisms such as fungi or bacteria. It should be noted that this product is not pharmacopoeia grade and cannot be used in medical devices or drugs.br&gt;br&gt;<br>This product has been classified by the International Union of Pure and Applied Chemistry (IUPAC) as a 2-(3-(aminoc</p>

<p>3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide is an analytical standard, used for HPLC analysis of impurities. It is also used as a reference in certain pharmacopoeia standards, such as the USP and EP. 3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide has a purity of 99% and can be found in the drug product Impurity Standard.</p>

<p>Acarbose EP Impurity D is a polymerase chain reaction (PCR) product that is produced by the subtilis, which is a bacterium. Acarbose EP Impurity D has been shown to inhibit the growth of viruses and bacteria in vitro. It inhibits the synthesis of bioactive molecules by inhibiting the activity of cellular enzymes, such as polymerase chain reaction products. Acarbose EP Impurity D also inhibits viral replication and has been shown to have an inhibitory effect on HIV-1 protease.</p>

<p>Acetamidodiphenyl ether (AEP) is a toxic environmental chemical that is used in the manufacture of plastics, rubber and pesticides. This compound has been shown to be able to cross the blood-brain barrier and accumulate in the brain, causing inflammation. AEP is also able to bind to astroglia and microglial cells in the brain, which are cells that play an important role in neuroinflammation. The accumulation of AEP in these cells leads to activation and demyelination, which are both damaging processes for neurons. Techniques such as immunofluorescence have been employed to study how AEP affects these cells at a molecular level.</p>

<p>DL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.</p>

<p>Ibuprofen is a nonsteroidal anti-inflammatory drug that is used to treat arthritis, rheumatoid arthritis, menstrual cramps and pain. Ibuprofen is a racemic mixture of two enantiomers, ibuprofen and S (+) -ibuprofen. The dextran sulfate method is an analytical method used to determine the concentration of ibuprofen in biological fluids such as human serum or urine. This test can be done by first treating the sample with trifluoroacetic acid (TFA) to convert ibuprofen to its glucuronide conjugate. The glucuronide conjugates are then deproteinized with hydrochloric acid, which converts them into their corresponding carboxylated derivatives. This conversion allows for the separation of ibuprofen from interfering substances using preparative hplc and quantification using mass spectrometry. Toxicity studies have been conducted on bacteria strains and inflammatory bowel</p>

<p>Please enquire for more information about rac Clavam-2-carboxylic acid sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sudan R-d3 is a medicinal compound that acts as a kinase inhibitor, targeting kinases involved in cancer cell growth and proliferation. It has been shown to inhibit the activity of several kinases in human urine and cancer cells. Sudan R-d3 is an analog of a Chinese herbal medicine used for its anticancer properties. This compound induces apoptosis, or programmed cell death, in tumor cells by inhibiting the activity of specific proteins involved in cell survival and proliferation. As such, Sudan R-d3 shows potential as an anticancer agent and may be useful for developing new cancer treatments.</p>

<p>Fadolmidine hydrochloride is a drug that has been shown to increase the movement of bowel contents in people with constipation. It may also be used to treat bone cancer, although it is not yet known if this drug will work as well as the current treatment options. Fadolmidine hydrochloride belongs to a class of drugs called antinociceptive agents, which have been shown to be effective in reducing pain and inflammation in patients with inflammatory bowel disease. The metabolic rate of fadolmidine hydrochloride is slow, and its side-effect profile is low. Pharmacokinetic properties include good chemical stability, rapid absorption from the GI tract, and moderate distribution throughout the body.</p>

<p>25-Hydroxyvitamin D2 3-hemisuccinate is a drug product that belongs to the group of natural products. It is a metabolite of vitamin D2 and has been shown to have anti-inflammatory properties. 25-Hydroxyvitamin D2 3-hemisuccinate is used as an analytical standard for HPLC, but it is also used in research and development for drug development. This product can be used as an impurity standard for API's because it is easily purified and stable in storage. Research has shown that this compound may be effective in protecting against osteoporosis, cardiovascular disease, and cancer.</p>

<p>2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid 2-(carboxymethoxy)-2-oxoethyl ester is a drug product that belongs to the class of Custom synthesis. It is a metabolite of loratadine, an antihistamine drug. The compound is a metabolite of loratadine, which is an antihistamine drug used for the treatment of allergies. It is produced by the oxidation of loratadine by cytochrome P450 enzymes and can be detected in urine at concentrations up to 5 ng/mL. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid 2-(carboxymethoxy)-2-oxoethyl ester has been shown to be effective in inhibiting the growth of bacteria that are resistant to penicillin and erythromycin.</p>

<p>Mono-(4-methyl-7-oxooctyl)phthalate (MMP) is a metabolite of the phthalate esters, which are synthetic chemicals used in plastics and other materials. MMP has been detected in the urine of neonates and preschool children, suggesting that it can be absorbed through skin contact. This compound is also found in wastewater, where it may cause estrogenic effects on human cells. The reaction solution of MMP with insulin-like growth factor (IGF) was studied by kinetic analysis and logistic regression to determine its binding affinity for IGF binding proteins. MMP has shown to be biodegradable under aerobic conditions.</p>

<p>Misoprostol Impurity 13 is a mixture of diastereomers from the synthesis of misoprostol. This material is not found in nature, and is not an impurity in any drug product. It has been synthesized for research purposes, to study the metabolism of misoprostol. The material is an analytical standard for HPLC, and can be used as a reference material for pharmacopoeia or drug development studies. Misoprostol Impurity 13 can also be used as a synthetic impurity standard for analytical HPLC.</p>

<p>Irinotecan is a drug product that is used in the treatment of cancer. It is a prodrug that must be activated by metabolism to its active form, SN-38. Irinotecan lactone impurity is an impurity standard and has been shown to have analgesic properties in mice. It has also been shown to inhibit the growth of colon cancer cells.</p>

<p>4-Carboxy-3-ethoxy)phenyl acetic acid (CPAE) is a fluorescent compound that has been shown to have antidiabetic and luminescence properties. It absorbs light at wavelengths of 340, 405, and 455 nm and emits light at 525 nm. It also absorbs UV light at 310 nm and emits fluorescence at 495 nm. CPAE is formed by the condensation of two molecules of 4-carboxybenzaldehyde with one molecule of ethyl 3-ethoxypropanoate in the presence of a base. The crystals are monoclinic, with space group P2/c and lattice constants a = 12.872(1) Å, b = 7.319(1) Å, c = 17.814(2) Å, β = 98.664(9)°, Z = 2. The molecular weight is 182.24 g/mol and its molecular</p>

<p>MK-0249 is a potent inhibitor of hyaluronan-mediated tumor cell proliferation and migration. It targets kinases that are involved in cancer cell growth and survival, promoting apoptosis and inhibiting the growth of tumors. MK-0249 has been shown to be effective against various types of cancer, including breast, lung, colon, and pancreatic cancer. This anticancer drug also has somatostatin analog properties that can inhibit the secretion of hormones from certain types of tumors. MK-0249 is derived from Chinese urine and is one of several kinase inhibitors that have been developed to target specific human cancers. It has demonstrated promising results in preclinical studies and is currently undergoing clinical trials for the treatment of advanced solid tumors.</p>

<p>Perindopril-N-desethylpentanoate is a drug product that is used in research and development of new drugs. It belongs to the class of drugs called angiotensin converting enzyme inhibitors, which act by inhibiting the conversion of angiotensin I to angiotensin II. Perindopril-N-desethylpentanoate can be used for the manufacture of HPLC standards. It can also be used as an analytical standard for impurities found in API, and has been shown to have niche applications in metabolism studies. This compound is purified to high purity levels that meet pharmacopoeia requirements.</p>

<p>3,4-Bis(2-methoxyethoxy)benzoic acid ethyl ester is a compound that has been shown to have bactericidal activity against Gram-positive bacteria. It is currently being evaluated for use in the preparation of samples for microbiological analysis and as an antimicrobial agent. 3,4-Bis(2-methoxyethoxy)benzoic acid ethyl ester has been shown to inhibit the growth of tumor cells in vitro and may be useful in the treatment of cancers. This compound also inhibits the production of nitric oxide by nitro groups and hydrogen bonds with amino acids on proteins or carbohydrates that are required for bacterial cell wall biosynthesis.</p>

<p>BAMEA-O16B is a human analog with potent anticancer properties. This Chinese medicinal compound has been shown to induce apoptosis in tumor cells and inhibit the growth of cancer cells. BAMEA-O16B acts as an inhibitor of protein kinases, which play a key role in cell cycle regulation and are often overexpressed in cancer cells. This compound has been found to be effective against a range of cancers, including breast, lung, and colon cancer. In addition, BAMEA-O16B has been shown to have low toxicity and is excreted primarily in urine. This makes it a promising candidate for further development as an anticancer therapy.</p>

<p>(4S)-4-Cyclohexyl-1-(1,3 dioxopentyl)-L-proline is a synthetic, non-natural amino acid. It is a metabolite of the pharmaceutical drug product (2,5-dioxohexahydro-2H-pyrrolo[3,4-c]pyrazol-1(2H)-yl)acetic acid and has been used as an analytical impurity standard. The chemical formula for (4S)-4-Cyclohexyl-1-(1,3 dioxopentyl)-L-proline is C13H24N2O6. This compound has been synthesized by reacting 4S - 1,3 - dioxopentane with L - proline in the presence of sodium amide. The synthesis was conducted in a solvent mixture of methylene chloride/dimethylformamide (1:1). The molecular</p>

<p>This isopropyl 2-(3-nitrobenzylidene)acetoacetate is a reaction solution that can be used to produce the antihypertensive drug, methyldopa. The reaction time required for this solution to react is about two hours. This product also contains chloride and calcium antagonist, which are added as catalysts. The rate of this reaction depends on the temperature and concentration of organic solvent. Crotonic acid, dihedral, and the yield of this reaction depend on the purity of reagents. Impurities in this product include isobutyl and methylbenzene, but these are not harmful to human health. This product also contains piperazine and thionyl chloride as impurities.</p>

<p>Metroprolol succinate is a prodrug of metoprolol. It is used for the treatment of high-sensitivity c-reactive protein, which is an inflammatory marker that indicates the presence and severity of atherosclerosis. Metoprolol succinate also has anti-inflammatory properties and can be used to treat cardiac disorders such as congestive heart failure. The drug inhibits the growth factor-β1 pathway in cardiac cells, which may be due to its ability to inhibit cellular proliferation by inducing apoptosis. This drug also has a protective effect on the skeleton, preventing bone loss and osteoporosis. Metroprolol succinate can be used in sample preparation for hydrochloric acid digestion or particle size analysis.</p>

<p>Tetrahydro-2-[2-(4-hydroxyphenyl)-1-methylethyl]-4,6,8-isoquinolinetriol is a synthetic compound that is used as an analytical reference standard for the detection of impurities in drugs. It is also commonly used as an impurity standard when synthesizing drugs and has been shown to be metabolized through various pathways including oxidation by cytochrome P450 enzymes. Tetrahydro-2-[2-(4-hydroxyphenyl)-1-methylethyl]-4,6,8-isoquinolinetriol is also used in drug development research and development.</p>

<p>Rivaroxaban is an analog of the kinase inhibitor which has been shown to have potent anticancer activity. It works by inhibiting kinases that are involved in cancer cell growth and survival. Rivaroxaban induces apoptosis in human and Chinese hamster ovary cells, leading to tumor cell death. This drug also inhibits glutathione S-transferase activity, which plays a role in the detoxification of reactive oxygen species and other electrophilic compounds. Rivaroxaban has been found to be effective against a variety of cancer types, including breast, lung, prostate, and colon cancers. It is a promising candidate for use as an anticancer therapy due to its ability to inhibit protein kinases that are overexpressed in cancer cells.</p>

<p>4’-Chloro clomiphene citrate is a drug product that is used as an analytical standard and impurity in the pharmaceutical industry. This compound is a natural metabolite of clomiphene, and is found in urine, serum, liver, and brain tissue. 4’-Chloro clomiphene citrate has been shown to have anti-inflammatory properties.</p>

<p>6-Bromo-6-dehydro-17a-acetoxy progesterone is a drug product that can be used as an HPLC standard or as a synthetic intermediate. It is a natural metabolite of progesterone, which is also a natural hormone. 6-Bromo-6-dehydro-17a-acetoxy progesterone has been shown to have antihypertensive and vasodilatory activities, which may be due to its ability to bind to beta adrenergic receptors in the vascular system. This metabolite of progesterone has also been shown to inhibit the metabolism of testosterone by inhibiting the enzymes 17beta hydroxysteroid dehydrogenase and 5alpha reductase, which lead to an increase in testosterone levels in blood plasma.</p>

<p>Dihydroxy bendamustine sodium salt is a medicinal protein analog that has been shown to be effective in the treatment of various types of cancer. It works by inhibiting certain kinases that are involved in tumor growth and promoting apoptosis, or programmed cell death, in cancer cells. This drug has been found to be effective against amphetamine-resistant Chinese hamster ovary cells and has shown promising results in clinical trials for the treatment of different types of cancer. Dihydroxy bendamustine sodium salt is excreted primarily through urine and is considered to be a potent inhibitor of kinase activity. Its potential as an anticancer agent makes it an important tool for cancer research and treatment.</p>

<p>Fluticasone propionate dithioacid is a synthetic corticosteroid that has anti-inflammatory and anti-allergic effects. It binds to the glucocorticoid receptor, which prevents the release of inflammatory mediators. Fluticasone propionate dithioacid is used in research and development, as well as for custom synthesis and drug product development. This compound has been shown to have high purity and is often used as a pharmacopoeia or drug development standard. Metabolism studies have also been conducted on this compound.</p>

<p>Naringenin 4'-o-β-D-glucuronide sodium salt is an analog of naringenin, a flavonoid found in Chinese herbs and citrus fruits. It has been shown to possess potent anticancer activity by inhibiting cyclin-dependent kinases (CDKs) and inducing apoptosis in cancer cells. Naringenin 4'-o-β-D-glucuronide sodium salt acts as a protein kinase inhibitor that disrupts the signaling pathways involved in tumor growth and metastasis. This compound has been found to be effective against various types of cancer, including breast, lung, prostate, and colon cancer. It is excreted in human urine and can be used as a biomarker for evaluating the efficacy of cancer treatment. Overall, this sodium salt has great potential as an inhibitor of tumor cell proliferation and may be a promising therapeutic agent for cancer treatment.</p>

<p>Please enquire for more information about (E)-4-(2,6-Dimethoxystyryl)-3-methoxyphenol-d6 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(S)-Rexamino is an analog of kinases that acts as a potent inhibitor of protein kinase. It has been found to be effective in the treatment of cancer by inducing apoptosis in human cancer cells. (S)-Rexamino also has inhibitory effects on tumor growth and is considered an anticancer agent. This toxin has been shown to be effective against Chinese hamster ovary cells, which are often used in cancer research. Additionally, (S)-Rexamino can be detected in urine samples and may have potential as a diagnostic tool for certain types of cancers. With its potent inhibitory effects on kinases, (S)-Rexamino shows great promise as a potential treatment option for various forms of cancer.</p>

<p>Please enquire for more information about 3-(tert-Butylsulfinyl)propanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N,N-Dimethyl-N'-(4-methyl-2-nitrophenyl)-urea including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about rac N-tert-Butoxycarbonyl viloxazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Rac Methotrimeprazine maleate salt is a potent cancer drug that targets kinases, enzymes involved in regulating cell growth and division. It has been shown to be effective against various types of cancer cells, including those that are resistant to other forms of chemotherapy. Rac Methotrimeprazine maleate salt works by inhibiting the activity of these kinases, which prevents cancer cells from replicating and undergoing apoptosis. This drug is an analog of astaxanthin, a natural compound found in Chinese herbal medicine, and it has been shown to have similar effects on cancer cells. Rac Methotrimeprazine maleate salt is excreted primarily through urine and has minimal side effects compared to other cancer drugs such as methotrexate. This inhibitor is a promising new treatment option for patients with various types of tumors.</p>

<p>Paritaprevir is a medicinal compound that acts as an inhibitor of protein kinases. It has been shown to be effective against various types of cancer cells, including those found in the urine and tumors. Paritaprevir is an analog of a Chinese anticancer compound and has been shown to induce apoptosis in human cancer cells. This potent kinase inhibitor selectively targets specific kinases involved in cancer cell proliferation, making it a promising candidate for the treatment of cancer. Its ability to inhibit kinases also makes it an attractive therapeutic option for other diseases that involve aberrant kinase activity.</p>

<p>Please enquire for more information about 2-(2,5-Dichlorophenyl)benzo[D]oxazol-5-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Medimeform is an anticancer drug that targets cancer cells by inhibiting the activity of kinases, which are enzymes that regulate various cellular processes. It specifically targets cyclin-dependent kinases (CDKs), which play a critical role in regulating the cell cycle and promoting cell division. By blocking CDK activity, Medimeform can induce apoptosis, or programmed cell death, in cancer cells. This drug has been tested on human cancer cell lines and has shown promising results as a potential treatment for various types of tumors. In addition to its anticancer properties, Medimeform also has medicinal value in traditional Chinese medicine due to its ability to inhibit other protein kinases involved in inflammation and immune response. Overall, Medimeform represents a promising new class of kinase inhibitors with potential applications in cancer therapy and beyond.</p>

<p>Please enquire for more information about (3-Fluoro-4-morpholin-4-ylphenyl)carbamic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Diazaborine is an analog of the cyclin-dependent kinase inhibitor and has been shown to have anticancer properties. It induces apoptosis in tumor cells by inhibiting the activity of specific kinases involved in cell division. Diazaborine has been studied extensively in Chinese hamster ovary cells and human urine protein, showing potent inhibition of these kinases. This drug may be useful for the treatment of various types of cancer. Additionally, Diazaborine has been shown to act as a potent inhibitor of other proteins involved in cell signaling pathways, making it a promising candidate for future drug development.</p>

<p>Please enquire for more information about Pomalidomide N-carbonyl-3-nitrobenzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Olaparib impurity 14 is a metabolite of olaparib. Olaparib is a drug used to treat cancer by inhibiting the activity of PARP1, an enzyme that repairs DNA damage. This impurity is a compound that can be synthesized in high purity and quality with a custom synthesis service. It has been shown to have niche applications in pharmacopoeia, drug development, and analytical studies.</p>

<p>Please enquire for more information about Glimepiride EP Impurity F including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Tirofiban impurity 4 is a drug product. This compound is an analytical standard and is used in research and development. CAS No. 2250244-31-4, Metabolism studies, Natural, API impurity, Custom synthesis, Impurity standard, Synthetic, Drug development, Research and Development, niche, HPLC standard<br>High purity</p>

<p>Moiramide B is an analog of the protein kinase inhibitor indirubin. This potent inhibitor has been shown to induce apoptosis in cancer cells and inhibit tumor growth in human cancer cell lines. Moiramide B is a powerful anticancer agent that works by blocking the activity of kinases, enzymes that play a critical role in cell signaling pathways. It has been found to be particularly effective against Chinese hamster ovary cells and has demonstrated significant anti-tumor activity in vivo. Moiramide B is excreted primarily through urine and its pharmacokinetics have been extensively studied. This inhibitor holds great promise as a potential treatment for various types of cancers.</p>

<p>PF-4942847 is an anticancer drug that selectively inhibits a specific kinase protein, which plays a crucial role in the growth and survival of cancer cells. This inhibitor has been shown to induce apoptosis, or programmed cell death, in various types of human cancer cell lines. PF-4942847 has also demonstrated activity against Chinese hamster ovary tumor cells by inducing G1 phase cell cycle arrest. The drug has been found to be effective in preclinical studies, showing promise as a potential therapeutic agent for the treatment of cancer. Additionally, PF-4942847 can be detected in urine samples, making it a useful tool for monitoring treatment efficacy and pharmacokinetics. As a medicinal inhibitor with promising results, PF-4942847 holds great potential for future cancer treatments.</p>

<p>Zeta-stat is an analog of geniposide, a natural compound found in Chinese medicine. It is a potent inhibitor of kinases that play a key role in cancer cell growth and survival. Zeta-stat has been shown to induce apoptosis in human cancer cells and may have potential as an anticancer agent. This product can be detected in urine and has shown promising results as a tumor protein kinase inhibitor. With its powerful inhibitory properties, Zeta-stat has the potential to become an important tool in the fight against cancer.</p>

<p>Gemcitabine diphosphate triethylamine salt is an inhibitor that has been shown to be effective in the treatment of various forms of cancer. It works by inhibiting the activity of kinases, which are enzymes involved in the regulation of cell growth and division. Gemcitabine diphosphate triethylamine salt is a prodrug that is converted to its active form, gemcitabine, in vivo. This drug has been shown to inhibit the uptake of xylose by cancer cells, leading to decreased protein synthesis and induction of apoptosis. In addition, it has been found to be effective against human and Chinese medicinal tumor cells. Gemcitabine diphosphate triethylamine salt is a promising treatment option for patients with cancer who have not responded well to traditional chemotherapy or radiation therapy.</p>

<p>Please enquire for more information about 16α-Methyl clobetasone butyrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-[(1-Hydroxy-1-propyl)butyl]-6-methoxynaphthalene is a versatile compound that has various applications in different industries. It can be used as an ingredient in pharmaceuticals, cosmetics, and even as a flavoring agent. This compound exhibits potent antioxidant properties, making it beneficial for skincare products. It also has antimicrobial properties, which can help in the formulation of hygiene and personal care products. Additionally, 2-[(1-Hydroxy-1-propyl)butyl]-6-methoxynaphthalene has been found to have anti-inflammatory effects, making it suitable for use in topical creams and ointments for soothing irritated skin. With its diverse range of benefits, this compound is a valuable addition to any product formulation.</p>

<p>CDK4/6-IN-2 is an analog of a potent and selective CDK4/6 inhibitor that has shown promising anticancer activity. It works by inhibiting the activity of CDK4 and CDK6 kinases, which are involved in cell cycle progression and cancer cell growth. This inhibitor has been shown to induce apoptosis in human tumor cells, making it a potential candidate for cancer treatment. CDK4/6-IN-2 has been synthesized from urine samples of Chinese medicinal plants and has been extensively studied for its pharmacological properties. It is a highly specific protein kinase inhibitor that shows excellent potency against various types of cancer cells.</p>

<p>Binedaline is a potent anticancer drug that targets human kinases, which are proteins involved in cell signaling pathways. It is an analog of a medicinal compound found in Chinese urine and has been shown to induce apoptosis (programmed cell death) in tumor cells. Binedaline works by inhibiting kinases, which play a critical role in the growth and survival of cancer cells. By blocking these kinases, Binedaline prevents the cancer cells from proliferating and induces their death. This drug is a promising candidate for the treatment of various types of cancer and has shown great potential as a kinase inhibitor.</p>

<p>AZD8848 is a potent inhibitor of the protein kinase that has been shown to have anticancer properties. This analog of capsaicin has been tested in Chinese hamster ovary (CHO) and human cancer cell lines, where it was found to induce apoptosis and inhibit tumor growth. AZD8848 targets specific kinases involved in cancer cell proliferation and survival, making it a promising candidate for cancer treatment. In addition to its anticancer effects, AZD8848 has also been shown to have potential as a urine protein inhibitor, which could be useful in the diagnosis and monitoring of certain types of cancer. Overall, AZD8848 represents an exciting new avenue for the development of novel anticancer therapies.</p>

<p>Please enquire for more information about Benzyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fluocortolone Impurity 8 is a drug product. It is an impurity standard for fluocortolone and has been purified from natural sources. Fluocortolone Impurity 8 is a metabolite of fluocortolone and has been synthesized for research purposes. Fluocortolone Impurity 8 is also a drug product that has been developed by the Pharmaceutical Research and Development team at the company with CAS No. 87-69-2. Fluocortolone Impurity 8 can be used as an analytical standard, API impurity, or pharmacopoeia reference material in metabolic studies.</p>

<p>N-[2-[(1S)-5-Bromo-2,3-dihydro-6-(2-propen-1-yloxy)-1H-inden-1-yl]ethyl]propanamide is a synthetic compound that has been used as an analytical standard for HPLC. It has also been used in the development of drugs to treat cancer. It is one of the impurities found in the drug product and is also known as 2-[(1S)-5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(propenyloxy)indenyl]acetic acid. CAS No. 196597-85-0</p>

<p>nicotinic acetylcholine receptor antagonist</p>

<p>Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.</p>

<p>(S)-4-(2-Methylpropyl)-2-pyrrolidinone is a lactam that has been synthesized in the laboratory. It is an organic solvent that is used in the synthesis of other compounds. The compound has a potential for producing impurities, such as isopropyl and phosphite, during synthesis. (S)-4-(2-Methylpropyl)-2-pyrrolidinone can be synthesized by reacting 2-methylpropionic acid with one equivalent of methylamine. This reaction takes place in an organic solvent and requires kinetic control to avoid side reactions.</p>

<p>Applications 3,5-Diiodo-4’-O-methyl Thyroacetic Acid Ethyl Ester is a derivative of 3,5-Diiodo Thyroacetic Acid (D455140), the acetic acid analog of Thyroxine (T425601). It is a reactant in the preparation of bifunctional thyrointegrin inhibitors, thyroxine (T425601) and triiodothyronine (T795380).<br>References Bridoux, A. et al.: J. Enz. Inh. Med. Chem., 26, 871 (2011); Wilkinson, J.: Biochem. J., 63, 601 (1956); Wilkinson, J.: Chem. Ind., 1352 (1955)<br></p>

<p>Applications epi-Glycochenodeoxycholic Acid Sodium Salt-d7 is a labelled epimer analogue of Glycochenodeoxycholic Acid Sodium Salt (G641255), which is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.<br>References Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005);<br></p>

<p>Please enquire for more information about Vildagliptin nitrosamine impurity 1 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dapagliflozin Impurity 26 is an impurity that is found in the chemical analysis of Dapagliflozin. It is a metabolite, which is not present in the drug product and does not have any biological activity. Dapagliflozin Impurity 26 has been shown to be a high purity, analytical standard for HPLC and can be used as an API impurity for drug development. This compound can also be synthesized by natural or synthetic means.</p>

Carboxylic acids w/ alcohol function but w/o other oxygen function and their derivatives, nesoi

<p>3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid is a potent protein kinase inhibitor with anticancer properties. It is an analog of emodin, a natural compound found in Chinese medicinal herbs. This compound has been shown to inhibit the growth of cancer cells and induce apoptosis through the inhibition of various kinases. Its potential as an anticancer drug has been demonstrated in vitro and in vivo studies, where it has shown to reduce tumor size and metastasis. This compound has also been detected in human urine, suggesting that it may have potential as a diagnostic marker for cancer. The discovery of 3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid may lead to the development of new inhibitors for various kinases and improve cancer treatment options.</p>

<p>2'-Hydroxy-3-phenylpropiophenone is a nucleophile that is hydrogenated to form 2'-hydroxy-3-phenylpropionic acid. It is used as a precursor for the synthesis of chalcones, which are biotransformed by microorganisms to form enantiomers and dihydrochalcones. This substance also has pharmacological activity and multidrug resistance. It is used as a sweetener in foods and beverages.</p>

<p>Ivermectin Impurity K is an impurity in Ivermectin, a drug product. It is a natural substance that is synthesized by the metabolism of avermectins, or it can be obtained from fermentation. It has been shown to have anti-inflammatory properties in mice and rats. Ivermectin Impurity K is a metabolite of Ivermectin, which is an antiparasitic drug used to treat parasitic infections of the skin and lungs caused by roundworms and other parasites. This impurity has been shown to have anti-inflammatory properties in mice and rats.</p>

<p>Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.</p>

<p>Diflorasone 17-propionate is a synthetic corticosteroid with the chemical name of 9,11-difluoro-17-hydroxy-16-methylpregna-1,4,9(11)-trienoic acid 17-propionate. It is an impurity standard in the manufacture of diflucortolone acetate. Diflorasone 17-propionate is used in drug development and analytical studies for its high purity and pharmacopoeia quality. Its metabolite profile has been investigated using HPLC with UV detection. Metabolism studies have been conducted to determine the metabolic pathway of diflorasone 17-propionate in humans.</p>

<p>Please enquire for more information about Rosuvastatin (3R,5R) isomer calcium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.</p>

<p>Please enquire for more information about Clopidogrel EP Impurity B hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>