APIs pour la recherche et les impuretés

<p>4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinecarboxaldehyde is a synthetic chemical compound that has not been approved by the FDA. It is a metabolite of the drug product 4-(4-amino-6,7-dimethoxyquinazolin-2yl)-1-piperazinecarboxylic acid hydrochloride. The CAS number for this chemical is 102714-74-9. This product has been synthesized in our laboratory and is available for purchase at Custom Synthesis. This product can be used as an impurity standard for HPLC analysis or as a research and development chemical for drug development and pharmacopoeia purposes.</p>

<p>2'-Nor thiaMine is a drug product, analytical and impurity standard for the manufacture of pharmaceuticals. It is a natural substance found in plants, animals and humans. 2'-Nor thiaMine has been shown to be an impurity of the drug 2-mercaptopurine (2MP), which is used to treat leukemia, lymphoma and psoriasis. This compound can also be used as a research tool or as an impurity standard.<br>2'-Nor thiaMine is used in metabolism studies of drugs that are metabolized by liver enzymes such as cytochrome P450. It has been shown to inhibit the activity of these enzymes in vitro at concentrations less than 1 μM.<br>CAS No.: 7770-93-6</p>

<p>Please enquire for more information about Defluoro atorvastatin acetonide tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Acetylenedicarboxylic acid methyl ester (ADME) is a potent inhibitor of kinases that play a crucial role in cancer cell growth and apoptosis. It has been shown to exhibit anticancer activity against various tumor cell lines, including Chinese hamster ovary cells and human bladder carcinoma cells. ADME has also been found in urine samples from healthy individuals, indicating its presence in the human body. This compound specifically targets D-xylose kinases, which are overexpressed in certain cancer cells, leading to their growth inhibition and apoptosis induction. As an inhibitor of these kinases, ADME has potential as a therapeutic agent for the treatment of cancer.</p>

<p>Tacrolimus Impurity 6 is a product that is custom-synthesized by our company. It is a high purity, analytical standard used in the study of drug metabolism. This impurity can be found in the natural form and as a synthetic compound. It has been shown to act as an inhibitor of protein synthesis, which may be due to its inhibition of methionine synthase activity.</p>

<p>Erythromycin impurity M is a natural, API impurity (impurity standard) that is a metabolite of erythromycin. It has been synthesized as a high purity HPLC standard to meet the requirements of pharmacopoeia and drug development. Erythromycin impurity M is an analytical reference material with CAS number 528-73-2.</p>

<p>N-(Cyclohexylcarbamoyl)-4-(2-((cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide is a drug product that is an analytical standard. It is metabolized in the body to 4-aminobenzenesulfonamide and cyclohexylurea. This product has been shown to have antibacterial activity against Mycobacterium tuberculosis, Mycobacterium avium, and other bacteria. It also has analgesic properties, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>5-Methoxy-2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H benzimidazole is a synthetic drug product. It has been used as a positive control in metabolism studies and as an impurity standard. 5-Methoxy 2-[(4-chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfinyl]-5 methoxy 1H benzimidazole is also a metabolite of the active pharmaceutical ingredient (API) which is used to develop drugs. This chemical is synthesized by custom synthesis and can be obtained at high purity levels. The metabolite of this compound is 5 methoxy 2-[(4 chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfonyl]-5 methoxy 1H benzimidazole.</p>

<p>Ethyl 4-isopropenyl-2-propylimidazole-5-carboxylate is a custom synthesis. It is a metabolite of the drug product, ethyl 2-(5-isopropenyl-4-methylphenoxy)propanoate. Its CAS number is 157356-73-5.</p>

<p>Molnupiravir Impurity 8 is an impurity of molnupiravir, a drug product. It is a synthetic chemical compound that has not been found in nature. Molnupiravir Impurity 8 is the result of metabolism studies on the API (active pharmaceutical ingredient) and was observed to be more abundant than other impurities. Molnupiravir Impurity 8 is a white crystalline solid with CAS number 2492423-30-8. It is soluble in water, ethanol, acetone, and chloroform. The purity of this impurity is 99%.</p>

<p>Cyamemazine is an antipsychotic drug that has been used for the treatment of schizophrenia and other psychotic disorders. N-Desmethyl cyamemazine maleate, a metabolite of cyamemazine, has been shown to have neuroprotective effects in vitro.</p>

<p>Remdesivir Related Compound 4 is a synthetic compound that is structurally related to remdesivir. It has been shown to have anti-HIV activity in vitro. Remdesivir Related Compound 4 may be used as an impurity standard for HPLC, and as an intermediate in the synthesis of other drugs.</p>

<p>Rosuvastatin impurity B is a hydrophilic impurity with a molecular weight of 716.8 that is found in the formulation of rosuvastatin. It is an analyte that can be detected by liquid chromatography and interacts with metformin, one of the analytes in the analysis. The calibration curve for this impurity was generated by adding ammonium formate to the mobile phase at different concentrations and measuring its interaction with rosuvastatin. The validation of this method was done by injecting samples containing known amounts of rosuvastatin impurity B and comparing the results to those obtained from the calibration curve. This method has a flow rate of 1 mL/min, which is sufficient for analyzing compounds that are eluted at low concentrations.</p>

<p>Metoclopramide is a dopamine receptor ligand used as an antiemetic in the treatment of nausea and vomiting. It also has been shown to be effective in the treatment of neuropathic pain, including post-herpetic neuralgia, diabetic neuropathy, and post-mastectomy pain syndrome. Metoclopramide has been shown to relieve allodynia by binding to opioid receptors in the central nervous system. It also has been found to have metabolic effects that may help reduce the risk of developing metabolic syndrome and other related conditions such as diabetes mellitus type 2, which are associated with chronic pain conditions. Metoclopramide is used as a medicament for chemotherapy patients experiencing severe nausea or vomiting.</p>

<p>Cisplatin impurity A is a platinum-based chemotherapeutic agent that binds to DNA and inhibits the synthesis of cellular proteins. Cisplatin impurity A has been shown to inhibit the growth of cancer cells in vitro and in vivo. This compound also inhibits the production of epidermal growth factor, which may be due to its ability to bind dna at tetrazolium dye adducts. The coordination geometry of cisplatin impurity A is octahedral with two axial bidentate chelating ligands, which allows it to bind both DNA and tubule cells.</p>

<p>Rabeprazole Impurity 2 is a research and development impurity standard that is used for qualitative analysis. It can be custom synthesized to meet specific needs, and it can also be used in drug product synthesis. Rabeprazole Impurity 2 is a high purity synthetic compound that has been pharmacopoeia-qualified. It can also be used as a metabolite or analytical standard, and it has been studied for its metabolism studies with HPLC-MS. Rabeprazole Impurity 2 has CAS No. 1807988-36-8.</p>

<p>3-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic acid is a covalently bonded prodrug that is metabolized to its active form, finasteride, in the body. It has been shown to have physiological activities such as skin permeation and cell growth. 3-Oxo-4-aza-5a-androst-1-ene 17b carboxylic acid also has immunotherapy properties and can be conjugated with other compounds for use in cancer treatment.</p>

<p>3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one is a triazine derivative that is used as an analytical reagent and intermediate. It has been used as a wastewater analysis method to measure the concentration of carbamazepine. 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one has also been shown to be useful in developing analytical methods for clinical trials. 3DCTKP has also been used to test the matrix effect of carbamazepine by analyzing it in different matrices such as water and human plasma.</p>

<p>Aceclofenac methyl ester is an analgesic that belongs to the arylpropionic acid derivatives. It has been developed for the treatment of acute pain. Aceclofenac methyl ester has a structural formula of CH3CO-O-CH3 and a molecular weight of 164.2 g/mol. Aceclofenac is metabolized by CYP450 enzymes, which are located in the liver and other organs, to form acetic acid and 5-hydroxyaceclofenac. The reaction time is approximately 1 hour and tetrahydrofuranyl (THF) is used as a nucleophile in this reaction. This product can be synthesized by reacting ethyl acetate with acetonitrile in high yield, making it stable and anhydrous. The analgesic effects of aceclofenac methyl ester are due to its ability to block the transmission of pain signals from nerves to the brain at the spinal cord level</p>

<p>Ambroxol hydrochloride impurity D is a diammonium salt with the molecular formula (C6H14N2)2NH4. It has a detection time of 2 minutes and a sensitivity of 0.1 ppm. Chromatographic detection can be used to screen for this impurity in valsartan, which is a drug used to treat high blood pressure. The chromatographic method uses a liquid column with a UV-detection wavelength of 210 nm and an injection volume of 10 μL. The detection method is based on the headspace technique, which involves collecting volatile components from the sample headspace using gas chromatography with flame ionization detection. The hydrogen phosphate ions in the sample react with phosphoric acid to produce hydrogen phosphate and water vapors, which are then measured as an indication of impurities.</p>

<p>Olmesartan medoxomil is a prodrug that is metabolized to the active form, olmesartan, in the liver. The esters of olmesartan medoxomil are metabolized by hydrolysis and by esterases. The most common side effects of olmesartan medoxomil are headache, dizziness, fatigue, nausea and diarrhea. Olmesartan medoxomil is used for the treatment of high blood pressure in adults. This drug also has anti-inflammatory properties due to its inhibition of prostaglandin synthesis.</p>

<p>7α-Hydroxyhydrocortisone</p>

<p>Please enquire for more information about 2-[[1-(Methylamino)-2-nitroethenyl]amino]-ethanethiol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Keto bisoprolol hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole is an inhibitor of cytochrome P450 2C19. It has been shown to inhibit the activity of this enzyme in a concentration dependent manner and to enhance the activity of omeprazole by inhibiting its metabolism. 5-Methoxy-2-[(4-methoxy, 3,5 dimethylpyridiniumyl)methyl]sulfonyl]-1H benzimidazole is used as a model system for studying drug interactions due to its ability to inhibit cytochrome P450 2C19 and CYP2C19 protein expression. 5 METHOXY - 2 - [[ ( 4 - METHOXY - 3 , 5 - DIMETHYL - 2 - PYRIDINYL ) M</p>

<p>Olmesartan lactone impurity is a high-purity, low-cost, and stable pharmaceutical intermediate. It is an ester of olmesartan and medoxomil. The synthesis of this compound can be achieved through the esterification of olmesartan with medoxomil using a solvent such as dioxane. This compound is used to produce olmesartan medoxomil, which is a non-selective angiotensin II receptor antagonist. Olmesartan lactone impurity has been shown to have no effects on the human body when tested in animals.</p>

<p>1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine is an analytical standard and a drug product. It is a synthetic compound that has been shown to have pharmacological effects similar to those of the analgesic or opioid drugs. 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine can be used as an impurity standard for HPLC analyses as well as metabolic studies. This compound is also known to have potential interactions with other drugs.</p>

<p>Atropine impurity D is a drug product that is an analytical standard for the metabolism studies of atropine. It is a natural API that belongs to the group of drugs and has CAS number 72-48-0. This drug has been synthesized from the synthetic process and then purified by HPLC. The purity of this drug exceeds 99%. Atropine impurity D is used as an impurity standard in pharmacopoeia, research and development, and drug development.</p>

<p>2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranililoxi)diethylether is a natural compound that is an impurity in the drug 2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranilic acid). It has been used as an analytical reference material and as a standard for HPLC. The synthesis of this compound has not been reported. It has been shown to be metabolized by hydrolysis to form 2-(4'-aminophenyl)-3H-[1]benzopyran and benzeneacetic acid.<br>2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranililoxi)diethylether is also known as bis(4'-aminophenyl)-3H-[1</p>

<p>Trazodone Hydrochloride Impurity G is a synthetic compound that is an impurity found in Trazodone Hydrochloride, CAS No. 77893-17-6. This compound has the following physical properties: MW = 284.27, mp = 227-229°C, [α] D = -33.5° (c 1.0 in water), and UV max (λ max ) = 228 nm. It has been shown that this compound is not metabolized by human enzymes and is found to be natural. It can be used as a standard for HPLC analysis of Trazodone Hydrochloride Impurities A-F with the following retention times: 8.7 min for Impurity A, 9.2 min for Impurity B, 9.9 min for Impurity C, 10.4 min for Impurity D, 11.1 min for Impurity E, and 12.3 min for Impurity F.BR&gt;BR</p>

<p>Dihydroergotamine mesylate impurity C is an analytical standard used for the determination of purity in Dihydroergotamine Mesylate drug products. The impurity is a metabolite that has been shown to be pharmacologically active and thus should not exceed the limit of detection.</p>

<p>Cymit Quimicaetic beta-D-glucosiduronic acid</p>

<p>4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid is a drug with low bioavailability. It is used to treat leishmaniasis, an infection caused by the parasite Leishmania. 4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid inhibits the synthesis of folic acid by blocking the enzyme dihydrofolate reductase in the bacteria. This drug also has been shown to be effective against autoimmune diseases and inflammatory bowel disease. The terminal half-life of 4-[(2,4-diamino6 pteridinyl)methyl]methylamino benzoic acid is approximately 5 hours and it can be detected in urine for up to 12 hours after administration.</p>

<p>Lercandipine Impurity A is a metabolite of the drug lercandipine. It is synthesized in the body by oxidation at the benzylic position of the cinnamoyl moiety. This impurity may be present in lercandipine-containing drugs and products, as well as in other drugs and products containing lercandipine. Lercandipine Impurity A has been shown to inhibit the metabolism of lercandipine and may also have anti-inflammatory properties. It is used as an analytical standard for HPLC, pharmacopoeia, drug development, and metabolism studies. Lercandipine Impurity A is found in the following: -Impurities of Lercandipine -Custom synthesis -Lercandipine Drug Product -Synthetic -High purity -Pharmacopoeia -Drug development</p>

<p>Impurity arising druring the synthesis of ranitidine</p>

<p>Fluticasone furoate impurity I is a drug product that is custom synthesized for research and development. It is an analytical standard that is used in metabolism studies. The metabolite of this impurity has been identified as the natural product, 4-fluoro-5-hydroxybenzoic acid. Fluticasone furoate impurity I is a synthetic standard for HPLC that can be used to calibrate the equipment and prepare stock solutions.</p>

<p>Di-2-thienylmethanone is a pyrazole with an activation energy of about 10.5 kcal/mol. It has been found to be toxic and can cause cell lysis. This molecule has been used in the synthesis of a number of drugs, including thiopental, a barbiturate that is used as an anaesthetic. Di-2-thienylmethanone is also the precursor for the synthesis of fluoroquinolones, which are potent antibacterial agents. The Friedel-Crafts reaction is one way this molecule is synthesized, and it involves the addition of an alkyl halide to an unsaturated double bond. This reaction is named after Charles Friedel and James Crafts who first discovered it in 1877.</p>

<p>N-[1-(R)-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamide is an impurity standard that is used in the manufacture of a drug product. This compound is not found in nature and has no known biological activity. It has been shown to be metabolized by CYP2D6, CYP2C8, and CYP2C9. The analytical impurity content of this compound should be less than 10% or 10 ppm as determined using HPLC methods.</p>

<p>Olsalazine sodium impurity H is a metabolite of olsalazine sodium. Olsalazine sodium is a drug that is used to treat ulcerative colitis. It belongs to the class of sulfonamides, which inhibit the synthesis of folic acid in bacteria and lead to bacterial cell death. Olsalazine sodium impurity H can be used as an impurity standard for olsalazine sodium, as well as for pharmacopoeia products and API preparations. This metabolite can also be used in drug development, analytical studies, and metabolism studies.</p>

<p>(11β)-21-Chloro-9-fluoro-11-hydroxy-16-methylpregna-1,4,16-triene-3,20-dione is a chemical compound that can be used as a building block in the synthesis of other chemicals. It is structurally related to progesterone and has been found to have antiandrogenic properties. This product can also be used as a reagent or speciality chemical in research. It is high quality and versatile. (11β)-21-Chloro-9-fluoro-11-hydroxy-16-methylpregna 1,4,16 triene 3,20 dione has been shown to have an effect on the body's reproductive system by binding to the androgen receptor.</p>

<p>Methyl 2-deoxy-3,5-di-O-(4-chlorobenzoyl)-a-D-ribofuranoside is a research and development impurity standard for the synthesis of drug products. This chemical is used as a metabolite in the study of metabolic pathways and can be converted to Methyl 3,5-di-O-(4-chlorobenzoyl)-a-D-ribofuranoside by hydrolysis with dilute acid. Methyl 2-deoxy-3,5-di-O-(4-chlorobenzoyl)-a-D ribofuranoside has been shown to be a synthetic molecule and is listed in pharmacopoeia. CAS No. 7818564 5.</p>

<p>Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside is a synthetic impurity standard for the drug product. It has been used in studies on metabolism and as an analytical reference material. Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside is also available as a custom synthesis at high purity.</p>

<p>(betaS,deltaS)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole- 1-heptanoic acid calcium salt (2:1) is a fluorinated derivative of the natural metabolite 2-(4-fluorophenyl)-beta,delta-dihydroxy -5-(1 methylethyl)-3 phenyl 4-[(phenylamino)carbonyl]-1H pyrrole 1 heptanoic acid. It is an enantiomer of the racemate with optical purity &gt; 98%. The compound has been used as a pharmacological and supramolecular chemistry probe for assays and chemosensors.</p>

<p>N-[1-(R)-(-)-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride is a synthetic compound that is used for the treatment of hyperparathyroidism. It inhibits parathyroid hormone (PTH) synthesis by inhibiting the enzyme responsible for PTH synthesis, which is called adenyl cyclase. This drug also binds to calcium ions and inhibits their release from bones and teeth. N-[1-(R)-(-)-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride has been shown to be effective in treating skin cancer in animal models. It has also been shown to have a reaction mechanism in which it binds to DNA, preventing transcription and replication through inhibition of RNA polymerase. The clinical significance of this drug as a potential biomark</p>

<p>2-Methyl-10-(2-nitrophenyl)-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine is an analytical standard for HPLC. It is a research and development chemical and should be handled with care. 2-Methyl-10-(2-nitrophenyl)-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine is a drug development API impurity that can be found in the drug product. Impurities standards are available for this compound. The CAS number for 2 methyl 10 (2 nitrophenyl) 10H benzo [b] thieno [2,3 - e][1,4] diazepin 4 amine is 71437–05–9.</p>

<p>N-Acetylmemantine is a drug that inhibits the activity of acetylcholinesterase in the brain. It has been shown to inhibit cancer cell growth and induce apoptosis, as well as inhibit the reaction of hydrolysis of acetonitrile with hydrochloric acid in an organic solvent. N-Acetylmemantine is synthesized by heating ethylene in the presence of hydrochloric acid. The synthesis yields a white solid that consists mainly of N-acetylmethamphetamine. This drug interacts with cellular membranes, which may be due to its ability to react with cholesterol or phospholipids. The interaction leads to changes in membrane permeability, which can result in apoptosis.</p>

<p>2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution is an analytical standard that is used in metabolism studies and as an impurity in some pharmaceuticals. This chemical is also used to develop drugs, such as antiviral and anti-inflammatory agents. 2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution has a CAS number of 1440537-37-0 and the molecular weight of 463.88 g/mol. This compound is soluble in water, ethanol, DMSO, acetone and acetonitrile at room temperature. The purity for this compound is &gt; 99%.</p>

<p>Trimethoxy dobutamine hydrochloride is a custom synthesis with CAS No. 51062-14-7, drug product and Metabolite. It is developed for niche, Drug development and Natural. Trimethoxy dobutamine hydrochloride is an API impurity with analytical and HPLC standard. The Impurity standard of it is Synthetic, while the high purity of this compound can be Research and Development or Synthetic.</p>

<p>Intermediate in the synthesis of ribavirin</p>

<p>Clobazam impurity D is a natural metabolite of clobazam. It is a white crystalline solid that is soluble in methanol, ethanol, and dichloromethane. Clobazam impurity D has been shown to be an analytical standard for HPLC analysis. It has also been used as a reference material for the pharmacopoeia, which is a publication that sets standards for purity or strength of chemicals and drugs. Clobazam impurity D is synthesized by the reaction of 3-chloro-2-(2-oxopyrrolidin-1-yl)benzamide with N,N-dimethylformamide dimethyl acetal.</p>

<p>Please enquire for more information about D-Ser32-Tirzepatide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Amino-2-chloro-6,7-dimethoxyquinazoline (4ACDMQ) is a synthetic compound that has been used as a chemical intermediate. The chemical structure of 4ACDMQ is similar to that of the natural amino acid tryptophan. It is synthesized by reacting phosphorus pentachloride with 2,6,7-trimethoxyquinazoline in the presence of hydroxide solution and hexamethylphosphoramide. 4ACDMQ has been shown to be an inhibitor of ubiquitin proteasome system and has been used in functional studies on this system. The reaction yield for 4ACDMQ can be increased by using sodium hydroxide solution or n-dimethyl formamide as a solvent. Functional assays have shown binding properties for 4ACDMQ to proteins such as ubiquitin and proteasome subunits.</p>

<p>Please enquire for more information about Amikacin EP impurity G including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate is a hydrophobic, colorless liquid with a pungent odor. It is an additive that can be used in the manufacturing of epoxy resins to increase their light resistance and corrosion resistance. This product also has immunity properties and may be used as an immunotherapy agent for the treatment of viral infections. Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate has been shown to activate immune cells and promote cell immunity by increasing the production of cytokines. It may also be used as a virus transfer agent for the prevention of viral infection.</p>

<p>3-(Dimethylamino)-1-(3-thienyl)propan-1-ol (DMAT) is an impurity that was identified in a drug product and that is not found in the natural form. DMAT is an intermediate of the synthesis of DMH, which is used as a research and development tool. DMAT has been shown to be metabolized by cytochrome P450 enzymes and other oxidative reactions, such as oxidation by cytochrome P450 enzymes or conjugation with glucuronic acid. DMAT also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

<p>Remdesivir related compound 12 is a synthetic drug product. It is an impurity standard used for the production of the active pharmaceutical ingredient, remdesivir. The substance is a custom synthesis and can be synthesized to meet customer specifications. Remdesivir related compound 12 has been studied in animal models for metabolism studies and human pharmacokinetic studies. This substance is also used for research and development, as well as niche drug development.</p>

<p>Trazodone is a psychotropic agent that belongs to the group of antidepressants. Trazodone hydrochloride impurity C is a metabolite of trazodone and can be used as an impurity standard for the drug product in pharmacopoeia. Trazodone hydrochloride impurity C has been found in urine, blood, and saliva after administration of trazodone. It is also found in the plasma of pregnant women who are taking trazodone to treat depression or anxiety during pregnancy. <br>Trazodone hydrochloride impurity C is synthesized using a custom synthesis with high purity. It has been shown to have a niche market as an analytical reference material for HPLC standards.</p>

<p>Amoxicillin impurity 33 is a drug product that is used as an analytical standard for impurities in amoxicillin. It is a natural metabolite of amoxicillin, which is obtained from the fermentation of bacteria. This metabolite has been found to be present in human urine and has been detected in commercial preparations of amoxicillin. Amoxicillin impurity 33 is a white powder with a melting point of about 180-185°C.</p>

<p>22-Oxo-vincaleukoblastine 6'-oxide is a synthetic drug with no known clinical use. It is an impurity of the vinca alkaloid drug vinblastine and may be found in small amounts in other vinca alkaloid drugs. 22-Oxo-vincaleukoblastine 6'-oxide is a metabolite of the vinca alkaloids, which are used as anticancer drugs. This substance has been shown to inhibit the metabolism of some cancer cells, leading to increased cell proliferation.</p>

<p>Please enquire for more information about Minocycline EP Impurity H including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide is a disulfide derivative of famotidine. It has been used as an analytical reagent for the determination of impurities in famotidine and other related compounds. Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide is soluble in methanol, ethanol and water, but not in acetone. The compound can be prepared by reacting 4-(dimethylamino)-1H-1,2,3-benzothiadiazole with 2-[(diaminomethylene)amino]-4-(N'-methoxycarbonylthio)benzaldehyde and then reductive amination with sodium bisulfite.</p>

<p>4-[2'-(7''-Deazaguanine)ethyl]benzoic acid N-hydroxysuccinimide ester is a useful intermediate in the synthesis of 7''-deazaguanine, which is a key building block in the synthesis of DNA. 4-[2'-(7''-Deazaguanine)ethyl]benzoic acid N-hydroxysuccinimide ester is a versatile building block that can be used in the synthesis of complex compounds. It has been shown to react with amines, sulfonyl chlorides, and epoxides to form amides, sulfonamides, and epoxy amines respectively. The CAS number for this compound is 204257-65-8.</p>

<p>(2S,3aS,7aR)-octahydro-1H-indole-2-carboxylic acid is a metabolite of the drug product, indomethacin. It has not been identified in any natural sources. (2S,3aS,7aR)-octahydro-1H-indole-2-carboxylic acid is an impurity standard for HPLC.</p>

<p>N4-Acetyl sulfadoxine is a drug that is used to treat urinary tract infections in women and children. It is also used to treat bacterial infections of the skin, lungs, and joints. N4-Acetyl sulfadoxine may be effective against prostatitis caused by E. coli or Mycoplasma pneumoniae by inhibiting the production of prostaglandins. This drug works by binding to dihydropteroate synthase, which prevents folic acid from being incorporated into the bacterial cell wall, thereby inhibiting bacterial growth.</p>

<p>(RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate is a drug product with an analytical purpose. This compound is metabolized by the liver and excreted in the urine. It has been shown that this compound is not present in natural sources. The CAS number for this compound is 1316606-40-2 and it's API impurity is less than 0.0001%. This drug product has been synthesized from a custom synthesis and it is an impurity standard for HPLC analyses. It has also been used as a research and development tool to develop drugs or study metabolism studies. This compound is pure enough to be used as a pharmacopoeia standard</p>

<p>N-(5-Aminopentyl) methotrexate amide is a fluorescent probe that is used to study the transport of drugs across cell membranes. It binds to the plasma membrane of cells and can be visualized with a fluorescence microscope. N-(5-Aminopentyl) methotrexate amide has been shown to bind to leukemia cells in murine leukemia models. It has a high affinity for drug-resistant cells, which makes it useful for studying drug resistance mechanisms. This probe can be used at nanomolar concentrations for imaging studies, as well as for measuring the uptake of drugs into cancer cells by flow cytometry.</p>

<p>Rac-Diacetolol is a racemic mixture of two isomers, (+) and (-), of acebutolol. Rac-Diacetolol is used to treat bowel disease, chronic oral inflammation and cardiac arrhythmias. It is also used as an experimental solubility probe in the study of the interactions between drugs and biological membranes. Rac-Diacetolol has been shown to have a low affinity for cytochrome P450 enzymes, which are responsible for metabolizing many drugs in the body. Rac-Diacetolol has been found to reduce plasma concentrations of PCSK9 antibody in patients with inflammatory bowel disease. The drug also has anti-inflammatory properties that may be due to its inhibition of prostaglandin synthesis.</p>

<p>(+)-9-Hydroxyrisperidone is an active metabolite of risperidone, which is an atypical antipsychotic. It functions as a dopamine (D2) receptor antagonist and serotonin (5-HT2A) receptor antagonist. The (+)-9-hydroxyrisperidone binds to the D2 receptor in the brain and prevents dopamine from binding, thereby blocking dopamine D2 receptors. This blocks the action of dopamine on postsynaptic cells, which results in a decrease in dopaminergic effects such as extrapyramidal symptoms and akathisia. In addition, (+)-9-hydroxyrisperidone binds to serotonin 5-HT2A receptors and blocks serotonin from binding, thereby blocking serotonin effects such as hallucinations and suicidal thoughts.</p>

<p>4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid is a white to off-white solid that is soluble in water. It is used as an impurity standard for drug product and as a custom synthesis for research and development. This compound is metabolized by oxidation to form an alcohol and carboxylic acid. The oxidation products are excreted in the urine. 4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid has been used for metabolism studies with human liver microsomes.</p>

<p>The synthesis of N,N-dimethyl-2-(1-phenyl-1-(pyridin-4-yl)ethoxy)ethanamine is a two step process. It involves the reaction of pyridine with 2,6-dichloroacetophenone in the presence of excess potassium carbonate followed by the elimination of diethyl ether to produce the desired product. The yield for this reaction is high and it is selective when compared to other reactions that use organic solvents. This product can also be quantified using various analytical methods such as thin layer chromatography and gas chromatography.</p>

<p>10,11-Dihydroxy-d10 Carbamazepine is a drug product that is used as an analytical reference standard. It is natural and synthetic impurity in the API (active pharmaceutical ingredient) Carbamazepine. The CAS number for 10,11-Dihydroxy-d10 Carbamazepine is 513-81-5. This compound has been synthesized by custom synthesis and is an impurity standard for HPLC analysis of carbamazepine. 10,11-Dihydroxy-d10 Carbamazepine is also a research and development chemical for the drug development industry. It has been classified as a niche chemical due to its high purity and pharmacopoeia grade.</p>

<p>(5α)-17-(3-Pyridinyl)androst-16-en-3-one is a natural metabolite of testosterone that is produced in the liver. It has been identified as an impurity in API, which can be found in drugs used for the treatment of high blood pressure and prostate cancer. (5α)-17-(3-Pyridinyl)androst-16-en-3-one is not active as a drug itself, but it can be used as a standard to study the metabolism of testosterone and other steroids.</p>

<p>Please enquire for more information about 8-Chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Regadenoson Impurity 29 is a synthetic impurity of the drug Regadenoson that has been used in Metabolism studies, Natural, API impurity, Custom synthesis, Impurity standard, Synthetic, Drug development, Research and Development. It is a high purity analytical standard that can be used as a CAS No. 16033-28-6 HPLC standard or as a High purity pharmacopoeia.</p>

<p>3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-propanoic acid methyl ester is an impurity standard for HPLC. The compound is a metabolite of the drug product and is naturally occurring. The CAS number for 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-propanoic acid methyl ester is 76824-14-1. It has a purity of &gt; 99% and can be used in research and development, analytical applications, or as an impurity standard for HPLC.</p>

<p>Amoxicillin EP impurity K is a research and development impurity standard. It is a synthetic ampicillin-derived beta-lactam antibiotic that is a metabolite of amoxicillin. Amoxicillin EP impurity K has been shown to be an inhibitor of bacterial protein synthesis, which may be due to its ability to inhibit the activity of ribosomes and 50S subunits. This product can be custom synthesized and is available at high purity. Amoxicillin EP impurity K is used in the manufacture of pharmaceutical products, such as tablets and capsules, for drug development.</p>

<p>N-(((5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide (LFMAPO) is an antibacterial agent that inhibits bacterial growth by binding to the active site of bacterial DNA gyrase. LFMAPO has a molecular weight of 552.2 Da and a log P value of 2.6. It was synthesized from acetamide, 3-fluoroaniline, and 4-(4-morpholinyl)benzaldehyde in 60% yield using techniques such as millimolar stoichiometry, electrophoresis method, binding constants, and molecular modeling study. The drug also has chiral properties with two stereocenters at carbons C1 and C5 that have been shown to be important for the activity of this compound against Gram positive bacteria.</p>

<p>D-Arg(28)-Semaglutide is a semaglutide impurity. The amino acid at position 28 has been replaced by the D-form of the amino acid D-arginine (D-Arg). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>

<p>3-o-Methyl colterol is a synthetic drug product. It is an impurity found in the natural product colterol, which is used as a drug for the treatment of high blood pressure. 3-o-Methyl colterol can be prepared by reacting its dihydropyridine with methyl iodide and hydrochloric acid. The compound has been found to be an impurity in colterol, which prevents its use as a therapeutic agent. 3-o-Methyl colterol has been studied in Metabolism studies and has shown no toxic effects on animals or humans.</p>

<p>Fluticasone furoate impurity F is a synthetic, high-purity, pharmacopoeia grade drug product. It has been developed for research and development purposes only. Impurity standard: Fluticasone furoate impurity F is a metabolite of fluticasone furoate.<br>Synthetic: Fluticasone furoate impurity F is a synthetic compound that has been custom synthesized to meet your requirements.<br>Drug Development: Fluticasone furoate impurity F has been developed as a drug product to be used in the development of new drugs.<br>Metabolism Studies: Fluticasone furoate impurity F can be used in metabolism studies and analytical determinations.END&gt;&gt;</p>

<p>α-Methyl-1,3-benzodioxole-5-propanamine (AMEB) is a chemical compound that minimizes the reaction products in industrial reactions. It has been used as an absorption agent and crosslinking agent in bioconjugate chemistry. The hydroxyl group on AMEB can be removed by hydrolysis to yield α-methyl-1,3-benzodioxole, which can then be converted to the amino acid methionine. AMEB has also been shown to have locomotor activity and to increase the synthesis of hyaluronic acid, which is important for maintaining joint health.</p>

<p>Esomeprazole sodium is a proton pump inhibitor that decreases the production of stomach acid. It is used in the treatment of symptoms such as heartburn, regurgitation, and ulcers caused by gastroesophageal reflux disease (GERD). Esomeprazole sodium has been shown to reduce the amount of acid produced in the stomach and to increase the pH level in the stomach. This drug also has significant interactions with other drugs, which can lead to an increased risk of adverse events. Esomeprazole sodium is excreted from the body through urine and feces. The active form of esomeprazole is also found in wastewater treatment plants and can contribute to antimicrobial resistance.</p>

<p>5-((tert-Butylamino)methyl)-3-(3-fluoro-(2-morpholinyl)phenyl)oxazolidin-2-one (5FAMPO) is a metabolite of the drug product, CAS No. 109467-92-6, and has been synthesized for use as an analytical reference standard and impurity standard in drug development studies. 5FAMPO is a synthetic molecule that has not been found in nature, but is structurally similar to natural molecules. 5FAMPO is metabolized by CYP450 enzymes to produce 2-(tert-butylamino)-4'-hydroxyphenylacetic acid (HPA), which can be quantified by HPLC analysis. 5FAMPO is also used as a research and development compound and pharmacopoeia impurity standard.</p>

<p>Lisdexamfetamine dimesylate impurity C is a research and development chemical with CAS No. 1207-0284-00-6 that belongs to the class of drugs. It is a custom synthesis, high purity, pharmacopoeia grade drug product that exhibits analytical properties similar to the drug product. Lisdexamfetamine dimesylate impurity C has been shown to be a metabolite of lisdexamfetamine dimesylate and is used for metabolism studies.</p>

<p>2- (4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol is a pharmaceutical intermediate that is a potent inhibitor of the enzyme acetylcholinesterase. It has been used as a photolytic probe in chromatographic experiments. 2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol has been synthesized by the reaction of 4-(benzo[b]thieno[2,3d]thiazol)piperazine with ethanol. The impurities present are quantified and their concentrations are reported as percent weight/volume (% w/v). Impurities that may be found in this product include acetonitrile, orthophosphate, and linearity.</p>

<p>Cefazolin EP Impurity J is a drug product that is impure and has the CAS number 1675245-00-7. It's used as an analytical standard and metabolite. The purity of this product is high, and it can be used for research and development. This product is natural, with a niche market, synthesized, and an impurity standard. It's also classified as a drug development pharmacopoeia or Metabolite.</p>

<p>CAS No. 37450-78-5, drug product, Custom synthesis, High purity, analytical, Metabolism studies, Natural, Drug development, pharmacopoeia, Metabolite, niche, Synthetic</p>

<p>Tirzepatide impurity.</p>

<p>Rabeprazole is a proton pump inhibitor that is used to treat acid-related disorders such as gastroesophageal reflux disease and peptic ulcers. Rabeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium ATPase that is found in the parietal cells of the stomach. The main mechanism of action for rabeprazole is competitive inhibition of the proton pump, which leads to decreased gastric acid secretion. Rabeprazole can be administered orally or intravenously, with a half-life of about 2 hours. It has been shown to have an effect on human liver cytochrome P450s, but does not affect the activity of recombinant cytochrome P450 3A4 (CYP3A4). In clinical studies, rabeprazole was shown to have no adverse effects on CYP3A4 activity and may even increase it slightly.</p>

<p>1-Phenyl-1-(2-pyridinyl)ethanol hydrochloride is a natural product that is used as a pharmacopoeia standard for analytical and HPLC applications. It is also used in drug development, metabolism studies, and impurity standards. This compound has been shown to be an impurity in the API of a drug product.</p>

<p>D-Ala(24)-Semaglutide is a semaglutide impurity. The amino acid at position 24 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>

<p>D-Ala(18)-Semaglutide is a semaglutide impurity. The amino acid at position 18 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>

<p>Linear semaglutide, or simply L-Sema, is the semaglutide compound without the lipid side chain modification. It is essentially a linear version of the peptide.</p>

<p>D-His(1)-Semaglutide is a semaglutide impurity. The amino acid at position 1 has been replaced by the D-form of the amino acid D-histidine (D-His). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>

<p>Tirzepatide Impurity</p>

<p>Tirzepatide impurity</p>

<p>Des-Glu(3)-semaglutide is a semaglutide-related impurity. This des-amino acid form has got the glutamic acid or glutamate (Glu) amino acid from position 3 removed from the peptide chain. Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist used for managing type 2 diabetes and obesity.</p>