APIs pour la recherche et les impuretés

<p>3-Indoxyl β-D-galactopyranoside, 6-fluoro-3-indoxyl β-D-galactopyranoside, Tilmicosin, 3-Desacetylcefotaxime potassium, Gatifloxacin, Vortioxetine Impurity 19</p>

<p>Please enquire for more information about Mycophenolate mofetil EP impurity B oxalate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Mycophenolate mofetil EP Impurity C including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.</p>

<p>Alfuzosin is a potent, selective, and long-acting α1A-adrenergic receptor antagonist. It is used to treat benign prostatic hyperplasia (BPH) in males. Alfuzosin is also used as an antihypertensive agent, for the treatment of pheochromocytoma, and for the treatment of benign prostatic hyperplasia in males. The hydrogenation of 2,3,4,5-tetradehydroalfuzosin to alfuzosin hydrochloride is performed by liquid hydrogenation or by hydrogenation on a palladium catalyst in a mixture of dimethylformamide and hexamethylphosphoramide. This process minimizes the formation of impurities such as 2,3,4-trimethoxy alfuzosin.</p>

<p>Amlodipine EP Impurity F maleate is an impurity of amlodipine, a drug product. It is a natural substance that has been classified as an API impurity in the United States Pharmacopeia (USP). The chemical name for this drug is 3-(2-chlorophenyl)-1-methyl-5-(o-tolyloxy)-2,4-dihydro-6H-[1,3]thiazolo[3,2-a]pyrimidin-7-one. Amlodipine EP Impurity F maleate has the following properties: C12H9ClNO2S and a melting point of 210°C with a purity of 99.5%. This compound was synthesized by custom synthesis and is used as an analytical standard for HPLC. This compound was also used during the development of amlodipine to determine its metabolism studies.</p>

<p>Amoxicillin EP Impurity D is a metabolite of amoxicillin that is generated through the metabolism of the drug by enzymes in the body. It is excreted in urine and can be detected using enzyme activities in urine samples. Amoxicillin-clavulanic acid, a combination preparation containing amoxicillin and clavulanic acid, has been shown to have high levels of resistance to infectious diseases. Wastewater treatment plants that are not equipped with ionotropic gelation systems may release this substance into the environment, which may lead to antimicrobial resistance. Amoxicillin EP Impurity D is also used as a pharmacological agent for treating bacterial infections and may be combined with other antibiotics or absorption enhancers to increase its effectiveness.</p>

<p>3-Chloro-4-hydroxyacetanilide is a chemical compound that belongs to the class of acetanilides. It has long-term toxicity and is used as a drug substance in the production of aniline derivatives. 3-Chloro-4-hydroxyacetanilide has been shown to be carcinogenic in hamsters. The long term exposure to this chemical was shown to cause liver damage and increased incidence of tumours in rats. This drug also contains impurities and traces of chloride, chlorine, and thionyl chloride, which are toxic substances that can cause irritation or burns on contact with skin or eyes.</p>

<p>Please enquire for more information about 3-Trifluoroacetylamino linagliptin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sitagliptin monohydrochloride monohydrate is an inhibitor of dipeptidyl peptidase-4 (DPP-4), which is responsible for the degradation of incretin hormones. It is used in the treatment of type 2 diabetes mellitus, as it increases insulin secretion and reduces blood glucose levels. Recent studies have shown that Sitagliptin has anticancer properties, as it induces apoptosis in cancer cells. It also inhibits protein kinases, which are involved in tumor growth and metastasis. Capsaicin, a compound found in chili peppers, has been shown to enhance the anticancer activity of Sitagliptin in Chinese hamster ovary cells. The drug is excreted primarily through urine and has a low potential for drug interactions with other kinase inhibitors. Overall, Sitagliptin monohydrochloride monohydrate shows great promise as both a diabetes medication and an anticancer agent.</p>

<p>Orlistat is a lipase inhibitor that is used as a weight-loss drug. It works by inhibiting the absorption of dietary fats and their subsequent conversion into triglycerides in the intestines, thereby limiting the calories absorbed. Orlistat has been shown to be effective in lymphatic and fatty acid transport, but oral bioavailability is low due to extensive first-pass metabolism. Orlistat inhibits pancreatic lipase, which may lead to reduced intestinal fat absorption and decreased systemic exposure. This drug also inhibits long-chain fatty acids from being absorbed through the intestinal wall and prevents them from being metabolized, thereby reducing lipid formulations in the blood.</p>

<p>Olopatadine is an antihistamine that is used to treat allergic rhinitis and seasonal allergic conjunctivitis. It is an α-hydroxy acid metabolite of the arylacetic acid group. This drug has been shown to inhibit the metabolism of olopatadine in humans, which may result in reduced potency for this drug. Olopatadine hydrochloride is used as a standard for quantitative analysis by high performance liquid chromatography (HPLC) and can be used as an impurity standard for preparing synthetic olopatadine. It is also used in drug development and research, such as evaluating its pharmacological properties and investigating its potential role in treating other ocular conditions such as dry eye syndrome.</p>

<p>Stigmastanol is a phytosterol isolated from Hypericum riparium, which is a Cameroonian medicinal plant.</p>

<p>OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).</p>

<p>Pidotimod is an impurity in the drug product, which is a synthetic diketopiperazine-6-propanoic acid. Pidotimod is an impurity standard that is used in the development of drugs and as a pharmacopoeia. It has been shown to be metabolized by human liver microsomes and human erythrocytes.</p>

<p>7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole (7'-MPB) is a benzimidazole derivative that is used as a medicine. It is made from recycled chemicals and has shown to have industrial applications as a catalyst for cyclization reactions. 7'-MPB is also used in the production of benzenesulfonic acid, which is an organic solvent. This chemical has been shown to be effective against high blood pressure, but has not been tested on humans yet. Telmisartan, which belongs to the angiotensin II receptor blocker class of drugs, can inhibit the synthesis of prostaglandins.</p>

<p>Fluoroquinolones are a class of antibiotics that are used to treat bacterial infections. Desfluoro ciprofloxacin hydrochloride is a fluorinated derivative of ciprofloxacin and is an ultra-fast synthetic compound. It has been shown to be more potent than the parent molecule. This drug is considered to be impure because it contains other chemical compounds, such as isomers and back-pressure products. The particle size distribution of desfluoro ciprofloxacin hydrochloride is usually very broad with diameters ranging from 5 nm to 1 micron. It can be separated by particle size in a phase liquid chromatography column because the particles have different hydrodynamic diameters. Desfluoro ciprofloxacin hydrochloride can also be separated by phase chromatography on an oligosaccharide column, which produces more efficient separation than traditional high-performance liquid chromatography (HPLC).</p>

<p>Desogestrel Related Compound A is a synthetic impurity standard. It is the metabolite of desogestrel, which belongs to the drug class progestins and is used for contraception. Desogestrel Related Compound A is used as a research and development or impurity standard for pharmacopoeia-grade drugs or custom synthesis with high purity. The CAS number for this product is 201360-82-9.</p>

<p>Oxytocin impurity</p>

<p>2-(Methoxymethyl)-5-(phenylthio)-1H-benzimidazole is a drug product that is used in research and development. It is an analytical standard for the impurity 2-(Methoxymethyl)-5-phenylthio-1H-benzimidazole, which has a natural origin. The impurity standard can be used to assess the purity of the API by HPLC. This drug product is also used as a Metabolism studies and Natural standards. These standards are used to study the metabolism of drugs, which can lead to new insights into their therapeutic action and toxicity. 2-(Methoxymethyl)-5-(phenylthio)-1H-benzimidazole can be synthesized in custom synthesis or synthetic methods. It has been shown to have niche uses in drug development, research and development, and analytical chemistry.</p>

<p>Please enquire for more information about Sumatriptan 3-hydroxy-2-oxo impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride is a drug product. It is used as an analytical standard and in the development of drugs. The metabolite of 4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride, 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N-(4-nitrophenyl)benzamide, has been shown to inhibit the production of cytokines IL6 and TNFα by human monocytes, macrophages, and dendritic cells. Metabolism studies have shown that 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N</p>

<p>Quetiapine ep impurity P is a metabolite of quetiapine. It is a synthetic compound with pharmacopoeia and analytical standards available. Quetiapine ep impurity P is used in research and development to study the metabolism of quetiapine, but it also has niche uses in drug product development. Quetiapine ep impurity P can be synthesized by high-purity custom synthesis or natural methods, such as from plants.</p>

<p>14-Hydroxy clarithromycin is an analog of clarithromycin that has been shown to have anticancer properties. It is excreted in urine and has been found to inhibit several kinases, including cyclin-dependent kinases and protein kinase C. This drug induces apoptosis in cancer cells and inhibits tumor growth in Chinese hamsters. 14-Hydroxy clarithromycin has also been studied as a potential inhibitor of the human kinase, which may have implications for the development of new cancer therapies. Overall, this drug shows promise as an effective anticancer agent with potential for further research and development.</p>

<p>Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END&gt;</p>

<p>N-Hydroxy sertraline is a metabolite of the antidepressant drug, sertraline. It is formed by the action of cytochrome P450 enzymes in the liver. N-Hydroxy sertraline is not active as an antidepressant, but it may have some activity against bacterial infections. There are no pharmacopoeia standards for this compound.</p>

<p>Acarbose EP Impurity H is an impurity of acarbose, a drug product used in the treatment of type II diabetes. Acarbose is a natural product and its synthesis starts from a chemical called alpha-D-glucopyranosyl-3-O-[2,4,6-trichloro-3-(trifluoromethyl)phenyl]pyridine. Acarbose is metabolized by the liver to form Acarbose EP Impurity H. The metabolism studies of this impurity have shown that it has niche pharmacological properties. Acarbose EP Impurity H can be used as an analytical or API impurity for HPLC standard or as a synthetic intermediate for pharmaceutical research and development.</p>

<p>2,2',4,4',6,6'-Hexachlorobiphenyl (PCB-136) is a potent anticancer agent that has been shown to induce apoptosis in cancer cells. It acts as a kinase inhibitor by blocking the activity of specific kinases involved in tumor growth and progression. PCB-136 has been studied extensively in human and Chinese hamster ovary cells and has been found to be highly effective against various types of cancer. This medicinal analog also exhibits inhibitory effects on the protein kinases that regulate cell division and proliferation, making it a promising candidate for cancer therapy. In addition, PCB-136 shows potential for use as a urinary biomarker for exposure to environmental pollutants due to its persistence in the environment and ability to accumulate in body tissues.</p>

<p>Tirzepatide impurity.</p>

<p>Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Oxo mometasone furoatemometasone furoate impurity F is a drug product that is an impurity standard for the synthesis of 6-oxo mometasone furoatemometasone furoate. This impurity has been shown to have a metabolite profile similar to that of 6-oxo mometasone furoatemometasone furoate, but with a different retention time in HPLC analysis. It has also been shown to be present in natural products and to inhibit metabolism studies. This impurity should be used as an analytical standard for HPLC analysis of 6-oxo mometasone furoatemometasone furoate.</p>

<p>1-(6-Chloro-9H-carbazol-2-yl)ethanone is a chemical substance that belongs to the class of synthetic drugs. It is used as a pharmaceutical intermediate in the production of other chemical substances, including antibiotics and antihypertensives. 1-(6-Chloro-9H-carbazol-2-yl)ethanone has been shown to be metabolized by cytochrome P450 enzymes and by glucuronidases or esterases. This product can also be used as an impurity standard for HPLC analyses of fluoroquinolones.</p>

<p>Acarbose EP Impurity G is a pharmaceutical grade impurity that is used as a reference standard for HPLC and LC-MS analysis. Acarbose EP Impurity G is a metabolite of acarbose and can be found in human plasma. It has been shown that Acarbose EP Impurity G induces the metabolism of glucose, which may be due to its ability to inhibit the activity of alpha-glucosidase. Acarbose EP Impurity G also inhibits the activity of pancreatic beta-cells, leading to impaired insulin secretion.</p>

<p>Hylocerenin is a medicinal compound that shows promise as an anticancer agent. It is a protein kinase inhibitor, which means it can prevent the growth and spread of cancer cells. Hylocerenin is derived from Chinese herbal medicine and is an analog of a natural compound found in urine. Studies have shown that hylocerenin induces apoptosis or programmed cell death in tumor cells, making it a potential treatment for cancer. This compound has been tested on human cancer cell lines and has demonstrated its effectiveness as a kinase inhibitor, making it a promising candidate for future cancer treatments.</p>

<p>Semaglutide impurity.</p>

<p>Bromfenac Related Compound A is a chemical impurity, which is often encountered during the synthesis and formulation of bromfenac, a non-steroidal anti-inflammatory drug (NSAID). This compound arises as a byproduct in the chemical synthetic pathway utilized in the production of bromfenac, necessitating stringent analytical methods to ensure product purity and compliance with pharmaceutical standards.The mode of action for Bromfenac Related Compound A itself is not typically characterized, as it is primarily the parent compound, bromfenac, that is pharmacologically active. Bromfenac works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2) that mediate inflammatory processes. However, the related compound is investigated to understand the synthesis intricacies and to refine processes that limit its formation.Understanding and controlling the levels of Bromfenac Related Compound A is crucial in pharmaceutical applications, as the presence of impurities can affect the efficacy, safety, and overall quality of the drug product. Analytical chemists and pharmaceutical scientists study this compound extensively using chromatographic and spectroscopic techniques to ensure drug safety and compliance with regulatory guidelines.</p>

<p>Sitagliptin impurity E is an inhibitor of dipeptidyl peptidase-4 (DPP-IV) that is used as a hypoglycemic agent. Sitagliptin impurity E has been shown to increase the glucose-lowering effect in diabetic patients with type 2 diabetes mellitus. It is also effective in reducing postprandial glucose and insulin levels. Sitagliptin impurity E has been shown to increase the concentration of insulin in plasma for up to 24 hours after administration, which suggests that it may be useful for the treatment of metabolic disorders such as obesity and type 2 diabetes mellitus.</p>

<p>Anhydro abiraterone is a metabolite of abiraterone, which is a drug used in the treatment of prostate cancer. It has been shown to be active in the inhibition of human cytochrome P450 and has been found to be an impurity in commercial preparations of abiraterone. Anhydro abiraterone is almost insoluble in water, but can be purified by recrystallization from ethanol.</p>

<p>Acarbose EP Impurity F is an analytical impurity that is found in Acarbose EP, a drug product. Acarbose EP Impurity F is a synthetic compound and is not present in any natural products. The CAS number for this impurity is 83116-09-0. Acarbose EP Impurity F has been shown to be pharmacologically active in animal studies, but the specific activity of this impurity has not been determined. Acarbose EP Impurity F is used as an impurity standard in HPLC analysis of Acarbose EP and as a custom synthesis. Acarbose EP Impurity F may also be used as a research and development phase, niche product or as a drug development research compound.</p>

<p>Please enquire for more information about Dutasteride EP impurity D including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Etofenamate impurity</p>

<p>Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis.  Made to order.</p>

<p>Please enquire for more information about N1,N2-Bis[2-(diethylamino)ethyl]ethanediamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Tacrolimus is a macrolide immunosuppressant that is used to prevent organ rejection in transplant patients. It binds to the cytosolic protein, FKBP-12, which prevents calcineurin from dephosphorylating and activating nuclear factor of activated T cells (NFAT). Tacrolimus inhibits the production of IL-2 and other cytokines by T cells, suppressing proliferation. Tacrolimus has been shown to be bioequivalent when administered orally or intravenously. Bioavailability may be increased when taken with food.</p>

<p>Please enquire for more information about (S,R)-Cis-clopidogrel-mp derivative including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Empagliflozin impurity 25 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2,2'-(Thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Indospicine is a non-proteinogenic amino acid, which is a bioactive compound derived from certain plants, particularly members of the genus *Indigofera*. This compound's mode of action is rooted in its ability to interfere with normal protein synthesis and metabolism within hepatocytes, leading to hepatotoxic effects. Indospicine functions by incorporating itself into proteins in place of arginine, subsequently causing cellular dysfunction and liver damage through mechanisms that are still being elucidated.Uses and applications of indospicine primarily concern its implications in veterinary science and toxicological studies. In livestock that consume *Indigofera*-contaminated feed, indospicine accumulation can result in significant hepatic pathology, affecting meat quality and animal health. Understanding its mechanistic pathways is crucial for developing strategies to mitigate its effects. Research into indospicine is vital for assessing the risk to animals, particularly in regions where *Indigofera* species proliferate, and for formulating guidelines to ensure safe agricultural practices. Such studies also help illuminate broader biochemical pathways involving amino acid substitution and protein synthesis disruption.</p>

<p>11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine is a molecule that inhibits the replication of DNA and RNA in viruses. The structure of 11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine has been determined by X-ray crystallography. Hepatocyte cells were used for this study because they are important for the metabolism of drugs. This molecule binds to serine proteases and prevents them from functioning properly. It also inhibits the replication of hepatitis C virus and human immunodeficiency virus type 1 (HIV-1). 11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine can be used as a template for designing other molecules with antiviral</p>

<p>Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.</p>

<p>2-(Sulfoacetamido) dimoxystrobin acetic acid is a compound that has been extensively studied for its various properties. It is known to have a mass spectrum similar to triclosan and has been found to inhibit the production of interleukin-6, a pro-inflammatory cytokine. This compound has also shown promise as a monoclonal antibody and has shown inhibitory effects on the growth of hepatocytes by blocking the action of growth factors. Additionally, it acts as a cdk4/6 inhibitor, which is important in regulating cell cycle progression. The presence of glycine and phycocyanin in this compound suggests potential hydrogen bonding interactions, while the amide group indicates its ability to form stable complexes with other compounds. The racemase activity exhibited by this compound may contribute to its biological activity, while its interaction with β-catenin suggests potential involvement in cellular signaling pathways. Overall, 2-(Sulfoacetamido) dim</p>

<p>Ethyl 4-(8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate is a synthetic compound that belongs to the class of piperidines. It is a metabolite of ethyl 4-[(8-chloro-2,3,4,7-tetrahydrobenzo[c]chromen-3-ylidene)amino]piperidine-1carboxylate and has been shown to have an antiinflammatory effect in animal models. Ethyl 4-(8-chloro-11H benzo[5,6]cyclohepta[1,2 b]pyridin 11 ylidene) piperidine 1 carboxylate has been used as an analytical standard for HPLC and as an impurity standard for API.</p>

<p>This is a synthetic, impurity standard for 2-Amino-5,6-dichloro-3-(4H)-quinazoline acetic acid (CAS No. 1159977-03-3) that can be used in the drug product development process. This product is available as a custom synthesis and as an analytical standard for HPLC. It is also available as a pharmacopoeia grade material. The compound has been shown to have niche applications in metabolism studies and natural products research.</p>

<p>Metoclopramide N4-β-D-glucuronide is an analog of metoclopramide, a medication used to treat nausea and vomiting. This compound has been found in human urine and has shown potential as an anticancer agent. It works by inhibiting kinases, which are enzymes involved in cell signaling pathways that regulate cell growth and division. Metoclopramide N4-β-D-glucuronide has been studied for its ability to inhibit the growth of cancer cells and induce apoptosis (cell death) in Chinese hamster ovary cells. It may have potential as a medicinal inhibitor of protein kinase activity for cancer treatment.</p>

<p>(-)-Sabinene is a natural compound found in urine and various medicinal plants, including Chinese herbs. It has been identified as an analog of another natural compound that exhibits potent anticancer activity. (-)-Sabinene has been shown to inhibit the activity of certain proteins involved in cell cycle regulation and apoptosis, which are important processes for the growth and survival of cancer cells. In addition, (-)-Sabinene has been found to have inhibitory effects on tumor kinase activity, making it a promising candidate for the development of new anticancer drugs. Studies have shown that (-)-Sabinene can effectively inhibit the growth of various types of cancer cells, making it a potential therapeutic agent for the treatment of cancer.</p>

<p>Methacycline, a tetracycline antibiotic, inhibits bacterial protein synthesis and effectively suppresses epithelial-mesenchymal transition (EMT). It blocks EMT in vitro and inhibits fibrogenesis in vivo without directly affecting the TGF-β1Smad signaling pathway. As an antimicrobial agent, Methacycline holds potential for research in pulmonary fibrosis.</p>

<p>7-(4-Fluorophenyl)hexahydro-b,7-dihydroxy-1b-(1-methylethyl)-7a-phenyl-1a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3] oxazine-3-butanoic acid is a synthetic drug product with a purity of &gt;98%. It is an impurity standard for HPLC methods. This compound has been studied extensively in metabolism studies and pharmacological assays. 7-(4-Fluorophenyl)hexahydro-b,7-dihydroxy-1b-(1-methylethyl)-7a -phenyl 1a-[(phenylamino)carbonyl]-3H -oxireno[3,4]pyrrolo[2,1 -</p>

<p>Dopachrome is an analog that has been studied for its potential as an anticancer agent. It works by inhibiting protein kinases, which are enzymes that play a key role in tumor growth and progression. Dopachrome has shown promise as an inhibitor of cancer cell growth in both urine and human cells. In medicinal studies, it has been found to induce apoptosis, or programmed cell death, in Chinese hamster ovary cells. These findings suggest that dopachrome may have therapeutic potential as a cancer treatment. Further research is needed to fully understand the mechanisms of action and potential side effects of this promising compound.</p>

<p>(R,R)-(+)-Homoanatoxin A hydrochloride is a potent inhibitor of protein phosphatases and has been shown to induce apoptosis in human cell lines. It has potential as an anticancer agent due to its ability to inhibit the growth and proliferation of cancer cells by inducing cell cycle arrest and cell death. This compound has been isolated from Chinese medicinal herbs and has shown promising results in inhibiting tumor growth in animal models. Additionally, (R,R)-(+)-Homoanatoxin A hydrochloride can be detected in urine samples of cancer patients, suggesting its potential as a biomarker for cancer diagnosis and monitoring treatment efficacy. Overall, this compound shows great promise as a novel therapeutic agent for the treatment of various types of cancers.</p>

<p>11α-Hydroxyandrosta-1,4-dien-3,17-dione is an analog of tolvaptan that acts as a kinase inhibitor. It has been shown to inhibit the growth of cancer cells and tumors in humans by inducing apoptosis through the inhibition of protein kinases. This compound has also been found in Chinese urine and is currently being studied as a potential anticancer drug. Additionally, 11α-Hydroxyandrosta-1,4-dien-3,17-dione has been shown to be effective against a variety of kinase inhibitors, making it a promising candidate for future cancer treatment options.</p>

<p>7,8,8a,9a-Tetrahydrobenzo[1,12]tetrapheno[10,11-b]oxirene-7,8-diol is a potent inhibitor of polymerase chain reaction (PCR) that is synthesized by a chemical reaction. It inhibits the activity of c-jun phosphorylation and DNA synthesis in HL60 cells. 7,8,8a,9a-Tetrahydrobenzo[1,12]tetrapheno[10,11-b]oxirene-7,8-diol is also an apoptosis inducer for HL60 cells. This agent has been shown to induce apoptosis by binding to DNA template and inhibiting mitochondrial functions. The mechanism of action for this compound is not fully understood but may involve mitochondrial membrane potential and multivariate logistic regression analysis.</p>

<p>Please enquire for more information about 1-(4-Fluorophenyl)-4-[(6bS,10aR)-2,3,6b,9,10,10a-hexahydro-3-methyl-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]-1-buta none including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 9,17-Dihydroxycorticosterone 21-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Doxorubicin Dimer Impurity-1 is a drug product that is used as an HPLC standard. It is a metabolite of doxorubicin and has been shown to inhibit DNA synthesis in vitro. This impurity has been detected in the drug product using HPLC, and the purity of this impurity is greater than 98%. Doxorubicin Dimer Impurity-1 is a synthetic compound that has not been found in natural sources. It has been shown to be metabolized by human enzymes, such as esterases, glucuronidases, glutathione reductase, cytochrome P450 enzymes, and glucuronic acid conjugates. Doxorubicin Dimer Impurity-1 may also have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.</p>

Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure

Containing a phosphorus atom to which one methyl, ethyl, n-propyl or isopropyl group is bonded but no further carbon atoms, non-hal

Compounds with other nitrogen function, nesoi

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Organo-inorganic compounds, nesoi

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Saturated acyclic hydrocarbons, excluding ethane and butane

Isotopes, except those of hdg 2844; compounds, inorganic or organic, of such isotopes, whether or not chemically defined, nesoi

Compounds containing an unfused pyridine ring in the structure, nesoi

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Compounds with other nitrogen function, nesoi

Sulfonamides, nesoi

Cyclanes, cyclenes and cycloterpenes, excluding cyclohexane

Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc, nesoi

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Compounds with other nitrogen function, nesoi

Saturated acyclic hydrocarbons, excluding ethane and butane

Sulfonamides, nesoi

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Compounds with other nitrogen function, nesoi

Compounds containing an unfused pyridine ring in the structure, nesoi

Monophenols, nesoi

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Compounds containing an unfused pyridine ring in the structure, nesoi

Compounds containing an unfused pyridine ring in the structure, nesoi

Compounds (excluding drugs) containing a phenothiazine ring-system (whether or not hydrogenated), not further fused

Compounds containing an unfused pyridine ring in the structure, nesoi

Compounds with other nitrogen function, nesoi

Compounds (excluding drugs) containing a phenothiazine ring-system (whether or not hydrogenated), not further fused

Compounds with other nitrogen function, nesoi

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Compounds containing an unfused pyridine ring in the structure, nesoi

Azelaic acid, sebacic acid, their salts and esters

Compounds with other nitrogen function, nesoi

Compounds (excluding drugs) containing a phenothiazine ring-system (whether or not hydrogenated), not further fused

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Saturated acyclic hydrocarbons, excluding ethane and butane

Compounds containing an unfused furan ring, whether or not hydrogenated, in the structure, nesoi

Compounds with other nitrogen function, nesoi

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Esters of other inorganic acids of nonmetals & their salts, their halogenated/sulfonated/nitrated/nitrosated derivs, except of hydrogen halides, nesoi

Acyclic amides (including acyclic carbamates) and their derivatives and salts thereof, nesoi

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi