APIs pour la recherche et les impuretés

<p>Tacrolimus is a macrolide that is used as an immunosuppressive drug. It has been shown to bind to the FK-binding protein, which in turn inhibits calcineurin. This prevents the release of IL-2, TNF-α and other cytokines. The immunosuppressive effects of tacrolimus have been evaluated using analytical methods such as coefficients, affinity, and monitoring techniques such as immunoassays and agglutination. These techniques are used to evaluate the plasma concentration of tacrolimus. Tacrolimus also binds to proteins in the blood samples and can be detected by turbidimetric or electrochemiluminescence immunoassay reagents.</p>

<p>Cetirizine metabolite</p>

<p>Decitabine impurity 14 is an impurity of decitabine. It is a stable, natural product that has been synthesized for use as an analytical standard and pharmacopoeia reference material. Decitabine impurity 14 is a white crystalline powder with a melting point of about 152°C. It is soluble in water, ethanol and ether. The chemical name for this compound is 2-amino-4,6-dihydroxypyrimidine-5-carbonitrile hydrochloride.</p>

<p>Pirtenidine is a potent and selective kinase inhibitor that has been shown to inhibit the activity of cyclin-dependent kinases. It has demonstrated promising results in preclinical studies as an anticancer agent, inducing apoptosis in cancer cells. Pirtenidine is an analog of protein kinase inhibitors, which have been used to treat various types of tumors. It has been found to be effective against human cancer cell lines and has shown significant tumor growth inhibition in animal models. Pirtenidine has also been reported to be a potent urine inhibitor of Chinese hamster ovary cells, making it a promising candidate for the treatment of urinary tract cancers.</p>

<p>3',5'-Di-O-p-chlorobenzoyl-2-deoxy-5-azacytosine is a drug product that is an impurity in the synthesis of 5'-azacytosine. The chemical name for 3',5'-Di-O-p-chlorobenzoyl-2-deoxy-5-azacytosine is 3,3'-di(O,O'-dichlorobenzyl)-2,5'-dideoxycytidine. It has a molecular weight of 302.7 g/mol and a melting point of 130°C. This chemical compound has been shown to be metabolized by human liver microsomes to a number of metabolites, including 2-, 3-, and 4-(hydroxymethyl)uracil and 4-(aminomethyl)uracil. 3',5'-Di-O-p-chlorobenzoyl -2 deoxy</p>

<p>Please enquire for more information about 4-[(3-Chlorophenyl)sulfonyl]benzenamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(Hydroxymethyl)-4-methyl sunitinib including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Desmethyl trimeprazine is a synthetic compound, which is an impurity of the drug product. It is not active and does not possess any biological activity. It is a metabolite of the parent drug, Trimeprazine. N-Desmethyl trimeprazine has been studied for its pharmacological properties and metabolism in the body, but no conclusive results have been found. The chemical structure and purity of N-Desmethyl trimeprazine are not listed in the USP or BP. This compound can be custom synthesized on request.</p>

<p>Bezafibrate is a drug product that is used in the treatment of hyperlipidemia. It is an impurity standard for bezafibrate 1-o-β-glucuronide, which can be used as an analytical standard for HPLC analysis. Bezafibrate 1-o-β-glucuronide can also be used to evaluate the metabolism of bezafibrate through animal studies.</p>