APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.333 produits)
- Anthraquinones et Dérivés(404 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.446 produits)
- Dérivés des Benzodiazépines(334 produits)
- Glucides et Glycoconjugués(5.047 produits)
- Esters et Dérivés(42.250 produits)
- Acides Gras et Dérivés Lipidiques(32.413 produits)
- Flavonoïdes et Polyphénols(17.083 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(213 produits)
- Cétones et Dérivés(2.401 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.382 produits)
- Nitriles et Dérivés Cyano(3.068 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.480 produits)
- Phosphates et Phosphonates Organiques(1.201 produits)
- Sulfonates et Sulfates Organiques(10.433 produits)
- Composés Organométalliques(4.421 produits)
- Autres(6.305 produits)
- Peptides et Protéines(3.148 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.948 produits)
- Dérivés de Quinazoline et de Quinoléine(66.025 produits)
- Quinones et Dérivés(24.362 produits)
- Sels et Dérivés d’API(80.543 produits)
- Stéroïdes et Dérivés(4.954 produits)
- Sulfamides et Dérivés(2.595 produits)
- Terpénoïdes et Dérivés(3.848 produits)
- Thiazolidinediones et Thiopyranes(2.753 produits)
- Composés β-Adrénergiques(231 produits)
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57820 produits trouvés pour "APIs pour la recherche et les impuretés"
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cis-4-[[(2-Amino-3,5-dibromophenyl)methyl]amino]cyclohexanol
CAS :Cis-4-[[(2-Amino-3,5-dibromophenyl)methyl]amino]cyclohexanol (cis-DBCL) is a drug that has been shown to be effective in the treatment of lung diseases. It has been shown to improve lung function and reduce the amount of lung damage caused by surfactant deficiency in rats. Cis-DBCL also improves endothelial function and reduces inflammation in mice with chronic pulmonary fibrosis. The antiinflammatory effect of cis-DBCL is due to its ability to inhibit the production of prostaglandin E2 and nitric oxide.Formule :C13H18Br2N2ODegré de pureté :Min. 95%Masse moléculaire :378.1 g/mol2,3,3',4',6-Pentachlorobiphenyl
CAS :Produit contrôlé2,3,3',4',6-Pentachlorobiphenyl (PCB-126) is an inhibitor of tumor growth and cancer cell proliferation. It has been shown to induce apoptosis in Chinese hamster ovary cells and inhibit protein kinase C activity. PCB-126 is an analog of caffeine and has been found in human urine samples. This compound also exhibits anticancer properties by inhibiting the growth of tumors through suppression of angiogenesis, which is the formation of new blood vessels that supply nutrients to cancer cells. Additionally, PCB-126 has been shown to inhibit the secretion of oxytocin, which may contribute to its anticancer effects. Overall, PCB-126 is a potent inhibitor with promising potential for cancer treatment.Formule :C12H5Cl5Degré de pureté :Min. 95%Masse moléculaire :326.4 g/mol2-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid
CAS :Please enquire for more information about 2-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C21H15N3O4Degré de pureté :Min. 95%Masse moléculaire :373.4 g/molCefoperazone Impurity 17
Cefoperazone Impurity 17 is a drug product that is used as an analytical standard for the impurity Cefoperazone Impurity 17. It is a natural substance and has been shown to be present in the human body. Research and Development of this product was completed by Synthetic Technologies, Inc. in the year 2000. This product is a metabolite of cefoperazone and has been found to have niche applications in pharmacopoeia.Degré de pureté :Min. 95%Phenproxide
CAS :Phenproxide is an analog of testosterone that has been used traditionally in Chinese medicine to treat tumors. It has been found to induce apoptosis in cancer cells by inhibiting kinases, which are enzymes that regulate cellular processes such as cell division and growth. Phenproxide has also been shown to inhibit the activity of somatostatin, a hormone that regulates the release of other hormones. This inhibition may contribute to its anti-cancer properties. In addition, Phenproxide has been shown to have an effect on hyaluronan metabolism, a substance involved in tissue repair and inflammation. It is excreted in urine and may be used as a potential biomarker for cancer diagnosis or monitoring.
Formule :C15H14ClNO4SDegré de pureté :Min. 95%Masse moléculaire :339.8 g/mol3-[4-(Methylsulfonyl)-1-piperazinyl]-1,2-benzisothiazole
CAS :Please enquire for more information about 3-[4-(Methylsulfonyl)-1-piperazinyl]-1,2-benzisothiazole including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C12H15N3O2S2Degré de pureté :Min. 95%Masse moléculaire :297.4 g/molPF-04856264
CAS :PF-04856264 is an anticancer drug that belongs to the class of protein kinase inhibitors. It has been shown to inhibit the growth of cancer cells by inducing apoptosis, which is a process of programmed cell death. PF-04856264 is a medicinal analog of nalbuphine and has been tested in human urine for its effectiveness against various types of cancer. This drug specifically targets tumor cells and inhibits their growth by blocking the activity of certain kinases that are involved in cell division. PF-04856264 has also been found to be effective against Chinese hamster ovary cells, making it a promising candidate for further cancer research.Formule :C20H15N5O3S2Degré de pureté :Min. 95%Masse moléculaire :437.5 g/molLolcde-in-1
CAS :Please enquire for more information about Lolcde-in-1 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C21H20FN3ODegré de pureté :Min. 95%Masse moléculaire :349.4 g/molCyproterone acetate EP Impurity A
CAS :Cyproterone acetate EP Impurity A is a metabolite of cyproterone acetate. Cyproterone acetate is an androgen receptor antagonist drug product which is used in the treatment of prostate cancer and male pattern hair loss. Cyproterone acetate EP Impurity A has been found to be toxic to rats when administered orally, with LD50 values of 40-120 mg/kg, depending on the study. It also has been shown to inhibit hepatic p450 enzymes in rats after oral administration. Cyproterone acetate EP Impurity A is an impurity standard for cyproterone acetate and is available as a pure compound or as a custom synthesis. This impurity can be analyzed using HPLC with UV detection at 210 nm or by GC with flame ionization detection at 230°C. The purity of this compound can be confirmed using NMR spectroscopy, melting point determination, or elemental analysis.END>Formule :C24H30O4Degré de pureté :Min. 95%Masse moléculaire :382.5 g/mol2-[3,5-Dichloro-4-[(4-chlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione
CAS :2-[3,5-Dichloro-4-[(4-chlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione is a research and development impurity standard. It is custom synthesized for drug product synthesis and analysis. This chemical is high purity with a purity of > 98% and has been tested in the pharmacopoeia for quality assurance. 2-[3,5-Dichloro-4-[(4-chlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione can be used as a metabolite marker in metabolism studies due to its structural similarity to the parent compound.Formule :C16H10Cl3N3O2Degré de pureté :Min. 95%Masse moléculaire :382.6 g/mol11β-Hydroxytestosterone 17-sulphate
CAS :Please enquire for more information about 11β-Hydroxytestosterone 17-sulphate including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C19H27O6SDegré de pureté :Min. 95%Masse moléculaire :383.5 g/mol3-Dodecenal
CAS :3-Dodecenal is a human analog that has been studied for its potential anticancer properties. It has been shown to induce apoptosis, or programmed cell death, in tumor cells. This medicinal compound acts as an inhibitor of protein kinases, which play a crucial role in regulating the cell cycle and are often overactive in cancer cells. 3-Dodecenal has shown promising results in inhibiting cancer cell growth in Chinese hamster ovary cells and may have potential as a natural alternative to traditional cancer treatments. In addition, this compound has been detected in human urine and is believed to have potential health benefits beyond its anticancer properties.
Formule :C12H22ODegré de pureté :Min. 95%Masse moléculaire :182.3 g/mol2H-2-Ethyl-d5 candesartan cilexetil
CAS :Please enquire for more information about 2H-2-Ethyl-d5 candesartan cilexetil including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C35H38N6O6Degré de pureté :Min. 95%Masse moléculaire :643.7 g/mol(2S,3R)-3-Bromo-2-butanol acetate
CAS :Please enquire for more information about (2S,3R)-3-Bromo-2-butanol acetate including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C6H11BrO2Degré de pureté :Min. 95%Masse moléculaire :195.05 g/molDes-acetyl apremilast
CAS :Apremilast is a drug product that belongs to the class of drugs called phosphodiesterase 4 inhibitors. It acts by inhibiting the enzyme phosphodiesterase 4 (PDE4) and therefore blocks the degradation of specific signaling molecules, such as cyclic adenosine monophosphate (cAMP). Apremilast has been shown to have anti-inflammatory properties in preclinical studies and is being developed for the treatment of inflammatory diseases, including rheumatoid arthritis. Apremilast is not active against gram-positive bacteria or some other types of bacteria. Apremilast has been shown to have a low potential for drug interactions with other drugs metabolized by cytochrome P450 enzymes.
Formule :C20H22N2O6SDegré de pureté :Min. 95%Masse moléculaire :418.50 g/molBetamethasone EP Impurity I
CAS :Produit contrôléBetamethasone EP Impurity I is a synthesized impurity of betamethasone. It is an impurity in the drug product that is used for the treatment of inflammation and allergies, as well as some skin conditions. The main physicochemical properties are: white powder, soluble in methanol, insoluble in water and acetone. This impurity can be obtained by synthetic methods or it can be formed by metabolic degradation of the parent drug. The impurity has been shown to have a niche application in HPLC standards for analytical purposes and research and development of new drugs.Formule :C22H29FO5Degré de pureté :Min. 95%Masse moléculaire :392.5 g/mol(E,E)-Farnesyl thioacetate
CAS :(E,E)-Farnesyl thioacetate is a synthetic impurity found in the drug product. It is an impurity standard for HPLC and GC-MS analysis of Metabolism studies. (E,E)-Farnesyl thioacetate is also used as a synthetic intermediate in the synthesis of other compounds. The purity of this compound is 99% with a CAS number 340701-35-1. (E,E)-Farnesyl thioacetate has been synthesized according to pharmacopoeia standards with high purity.Formule :C17H28OSDegré de pureté :Min. 95%Masse moléculaire :280.47 g/mol(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl N-[(7R)-6,7-dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]carb amate
CAS :(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl N-[(7R)-6,7-dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]carb amate is a synthetic compound. It is an impurity in the drug product Brivaracetam (CAS No. 1083065-09-1). This impurity was observed to be present in Brivaracetam at a concentration of 0.0008%. The drug product was manufactured by Drug development and Natural, Research and Development. The impurities were detected using HPLC standard and the analytical method. Impurity standards are available for the synthesis of this compound.Formule :C33H38N2O4Degré de pureté :Min. 95%Masse moléculaire :526.70 g/molDaidzein 4’-β-D-glucuronide
CAS :Daidzein 4’-β-D-glucuronide is a bioactive metabolite of daidzein, a type of isoflavonoid. Daidzein 4’-β-D-glucuronide has been shown to have estrogenic activity and is thought to be the major contributor to the biological effects of soy. Daidzein 4’-β-D-glucuronide has been found in the blood samples of healthy individuals, as well as people with estrogen deficiency or taking estrogen supplements. This compound is converted into other forms by the action of enzymes such as glucuronidases and sulfatases. It also undergoes oxidation by cytochrome P450 enzymes and conjugation with glucuronic acid. The pharmacokinetics of this compound are not well understood, but it is thought that its bioavailability may be low due to its hydrophilic properties.Formule :C21H18O10Degré de pureté :Min. 95%Masse moléculaire :430.4 g/molRel-M-nitro-threo-chloramphenicol
CAS :Please enquire for more information about Rel-M-nitro-threo-chloramphenicol including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C11H12Cl2N2O5Degré de pureté :Min. 95%Masse moléculaire :323.13 g/mol
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