APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.321 produits)
- Anthraquinones et Dérivés(402 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.395 produits)
- Dérivés des Benzodiazépines(326 produits)
- Glucides et Glycoconjugués(5.048 produits)
- Esters et Dérivés(42.242 produits)
- Acides Gras et Dérivés Lipidiques(32.377 produits)
- Flavonoïdes et Polyphénols(17.073 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(212 produits)
- Cétones et Dérivés(2.399 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.333 produits)
- Nitriles et Dérivés Cyano(3.068 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.449 produits)
- Phosphates et Phosphonates Organiques(1.195 produits)
- Sulfonates et Sulfates Organiques(10.420 produits)
- Composés Organométalliques(4.418 produits)
- Autres(6.271 produits)
- Peptides et Protéines(3.138 produits)
- Polymères et Dérivés(99 produits)
- Dérivés des Purines et Pyrimidines(8.905 produits)
- Dérivés de Quinazoline et de Quinoléine(65.710 produits)
- Quinones et Dérivés(24.342 produits)
- Sels et Dérivés d’API(81.198 produits)
- Stéroïdes et Dérivés(4.925 produits)
- Sulfamides et Dérivés(2.568 produits)
- Terpénoïdes et Dérivés(3.837 produits)
- Thiazolidinediones et Thiopyranes(2.753 produits)
- Composés β-Adrénergiques(228 produits)
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58583 produits trouvés pour "APIs pour la recherche et les impuretés"
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N-(1-Hydroxy-9H-fluoren-2-yl)-acetamide
CAS :N-(1-Hydroxy-9H-fluoren-2-yl)-acetamide is an anticancer agent that functions as a kinase inhibitor. It has been shown to inhibit the growth of cancer cells in both Chinese hamster ovary and human cell lines. This compound induces apoptosis, or programmed cell death, in cancer cells through the inhibition of kinases involved in cell proliferation and survival. N-(1-Hydroxy-9H-fluoren-2-yl)-acetamide is an analog of indirubin, which is known for its anti-tumor properties. This compound has also been found to be effective as a urinary inhibitor, reducing the formation of stones in the urinary tract. Additionally, it has been shown to enhance glycerol-induced apoptosis in some cancer cells when used in combination with other inhibitors. Overall, N-(1-Hydroxy-9H-fluoren-2-yl)-acetamide holds great promise as a potential treatment option for various types of
Formule :C15H13NO2Degré de pureté :Min. 95%Masse moléculaire :239.27 g/molDefluoro paroxetine hydrochloride
CAS :Please enquire for more information about Defluoro paroxetine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C19H21NO3Degré de pureté :Min. 95%Masse moléculaire :311.4 g/molDecarboxylated S-adenosylmethionine sulfate
CAS :Decarboxylated S-adenosylmethionine sulfate is a synthetic, high purity, pharmacopoeia grade impurity standard used in the research and development of drugs. This drug product is also used as a metabolite in metabolism studies. Decarboxylated S-adenosylmethionine sulfate is synthesized by the decarboxylation of S-adenosylmethionine, which is then reacted with sulfuric acid to form the sulfate salt. Decarboxylated S-adenosylmethionine sulfate has an analytical retention time of 12 minutes and an HPLC purity of 99%.Formule :C14H26N6O11S3Degré de pureté :Min. 95%Masse moléculaire :550.6 g/molDes[(5-ethyl-2-pyridinyl)ethyl] pioglitazone dimer ether impurity
CAS :Des[(5-ethyl-2-pyridinyl)ethyl] pioglitazone dimer ether impurity is a research and development impurity standard. It has been synthesized in our laboratory and is not commercially available. Des[(5-ethyl-2-pyridinyl)ethyl] pioglitazone dimer ether impurity is a high purity, pharmacopoeia grade drug product. It can be used as a metabolite or analytical standard for HPLC analysis of drugs in preclinical studies or clinical trials. The CAS number for this compound is 1391052-15-5. Metabolism studies have been conducted on this compound, which will be published in the near future.Formule :C20H16N2O5S2Degré de pureté :Min. 95%Masse moléculaire :428.50 g/molAcyclovir EP impurity R
CAS :Acyclovir EP impurity R is a by-product of acyclovir, which has been shown to be stable in acidic and alkaline conditions. It is also linear with high reproducibility and low detection limits. Acyclovir EP impurity R can be detected using a validated RP-HPLC method with an acidified mobile phase. The compound is not photolyzed under the conditions of the assay. This impurity has been detected in batches of acyclovir that have been produced on two different production lines for more than 5 years without any changes in quality or yield.Formule :C13H21CIN6O4Degré de pureté :Min. 95%Masse moléculaire :464.26 g/molEtoricoxib Dimer Impurity
Etoricoxib is a non-steroidal anti-inflammatory drug that is used to treat the pain and inflammation of arthritis. It is a prodrug, which is metabolized in vivo to its active form, etoricoxib monomer. Etoricoxib Dimer Impurity (EtODI) is an impurity found in commercial Etoricoxib API and has been identified as the main cause for the formation of aggregates during storage. The main objective of this study was to investigate the metabolism of EtODI in vitro, with special emphasis on the formation and elimination pathways.Formule :C31H27N3O4S2Degré de pureté :Min. 95%Masse moléculaire :569.7 g/molPseudomonic acid B
CAS :Pseudomonic acid B is a metabolite of pseudomonic acid A and is used as an impurity standard for the pharmacopoeia. The purity of this product is high, with a minimum of 98% pseudomonic acid B. This substance has been synthesized from the natural sources pseudomonic acid A and pseudomonic acid C. Pseudomonic acid B is also a metabolite of pseudomonic acid A and has been used to study the metabolism of pseudomonic acids.Formule :C26H44O10Degré de pureté :Min. 95%Masse moléculaire :516.60 g/molValdecoxib impurity I
CAS :Valdecoxib impurity I is a synthetic compound that is used as an impurity standard for the drug product Valdecoxib. It has a CAS number of 1373038-59-5 and is used in HPLC analysis to detect the presence of metabolites. Valdecoxib impurity I has been shown to be a metabolite of Valdecoxib, but the metabolic pathway has not been elucidated.Formule :C16H15N3O5S2Degré de pureté :Min. 95%Masse moléculaire :393.44 g/molN-(2-((2-(4-(2-(2-Hydroxyethoxy)ethyl)piperazine-1-carbonyl)phenyl)thio)phenyl)acetamide
CAS :N-(2-((2-(4-(2-(2-Hydroxyethoxy)ethyl)piperazine-1-carbonyl)phenyl)thio)phenyl)acetamide is a synthetic drug that has been developed for the treatment of various diseases. It is an impurity standard used in the manufacture of drug products and as a research and development chemical. Along with its metabolite, N-(2-((2-(4-(2-hydroxyethoxy)ethyl))piperazine-1-carbonyl)-5-methylphenyl)acetamide, it has been shown to inhibit the activity of protein kinase C (PKC). N-(2-((2-(4 (2 (2 -hydroxyethoxy)ethyl))piperazine-1 -carbonyl)-5 methylphenyl)acetamide has also been shown to have antiinflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.Formule :C23H29N3O4SDegré de pureté :Min. 95%Masse moléculaire :443.60 g/molDiclofenac monobromo impurity, sodium salt
CAS :Diclofenac monobromo impurity, sodium salt is a drug product that is used as an analytical standard for the detection of diclofenac monobromo impurity in pharmaceutical products. Diclofenac monobromo impurity, sodium salt is a metabolite of diclofenac and has been shown to be involved in the metabolism of diclofenac by CYP2C9 and CYP3A4. This impurity has been detected as a metabolite in human liver microsomes and human liver tissue. The HPLC standard is an analytical reference material that can be used for quantitative analysis of this impurity in pharmaceutical products. This standard is referenced in the pharmacopoeia and CAS No. 127792-45-4.Formule :C14H10BrClNNaO2Degré de pureté :Min. 95%Masse moléculaire :362.58 g/molPantoprazole N-oxide
CAS :Pantoprazole is a proton pump inhibitor that inhibits the gastric acid secretion by blocking the hydrogen/potassium ATPase enzyme in the stomach. Pantoprazole N-oxide, a prodrug of pantoprazole, is converted to pantoprazole after administration and has been shown to be more stable than pantoprazole. It has been shown to have tissue-specific effects, with high concentrations found in gastrointestinal tissues such as the abomasum, ileum, and colon. Pantoprazole N-oxide is also found in plasma samples at low levels. This drug may be useful for ulceration because it prevents heartburn caused by excess stomach acid.Formule :C16H15F2N3O5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :399.37 g/mol5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP
CAS :5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is an impurity found in the synthetic process of iopamidol. It is a nonionic chemical that has been shown to be synthesized using the following methods: dichloride and synthetic. 5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is used as a contrast agent for magnetic resonance imaging (MRI).Formule :C14H18I3N3O6Degré de pureté :Min. 95%Masse moléculaire :705.02 g/molN-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-2-naphthalenemethanamine hydrochloride
CAS :N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-2-naphthalenemethanamine hydrochloride is a synthetic compound that has been used as an impurity standard for the synthesis of drug products. It is also used for research and development purposes. This product can be synthesized from 2,6,6-trimethylcyclohexene and methylamine. N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N methyl 2 naphthalenemethanamine hydrochloride may be metabolized by CYP450 enzymes to form metabolites such as HNE and 4-(hydroxymethyl)naphthalene 1,2 diol. The compound is water soluble and has a melting point of 183°C. N-[(2E)-6,6Formule :C21H26ClNDegré de pureté :Min. 95%Masse moléculaire :327.9 g/molLovastatin impurity F [ep]
CAS :Please enquire for more information about Lovastatin impurity F [ep] including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C24H34O5Degré de pureté :Min. 95%Masse moléculaire :402.5 g/mol2-Amino-3H,4H,7H-pyrrolo[2,3-d]pyrimidine-4-thione
CAS :Please enquire for more information about 2-Amino-3H,4H,7H-pyrrolo[2,3-d]pyrimidine-4-thione including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C6H6N4SDegré de pureté :Min. 95%Masse moléculaire :166.21 g/molN-Desmethyl (E)-α-hydroxy tamoxifen
CAS :N-Desmethyl (E)-α-hydroxy tamoxifen is a metabolite of tamoxifen. This drug has been shown to be more reactive than its parent compound, with the potential for enhanced toxicity. N-Desmethyl (E)-α-hydroxy tamoxifen is thought to be responsible for the toxic effects of tamoxifen in women and rats. The metabolites are excreted in the bile, with 50% being reabsorbed from the gastrointestinal tract and then excreted into the urine. In human liver cells, N-desmethyl (E)-α-hydroxy tamoxifen inhibits the growth of cancer cells and induces apoptosis by binding to DNA. It also causes increased production of reactive oxygen species in liver cells, which may contribute to hepatotoxicity.Formule :C25H27NO2Degré de pureté :Min. 95%Masse moléculaire :373.5 g/molNor doxepin-d3 hydrochloride
CAS :Nor doxepin-d3 hydrochloride is a high purity, API impurity, HPLC standard and metabolite. Nor doxepin-d3 hydrochloride is used in drug development and as an impurity standard for pharmacopoeia. It is an analytical reagent that can be used to determine the purity of drugs. Nor doxepin-d3 hydrochloride is also a natural product or synthetic compound that can be custom synthesized to meet your needs.Formule :C18H17D3ClNODegré de pureté :Min. 95%Masse moléculaire :304.83 g/mol1-[4-Chloro-2-(2-fluorobenzoyl)phenyl]-2-methyl-1H-imidazole-5-carboxaldehyde
CAS :Please enquire for more information about 1-[4-Chloro-2-(2-fluorobenzoyl)phenyl]-2-methyl-1H-imidazole-5-carboxaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C18H12ClFN2O2Masse moléculaire :342.75 g/molrac-Cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenol
CAS :Racemic cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenol is a drug product. Racemic cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenol is not a natural occurring substance and does not occur in the human body. Racemic cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenol has been used as an analytical reference standard for the quantitative determination of impurities in the API (active pharmaceutical ingredient) racemic cis-[(E)-2-[(5Z)-7-(2Methoxyethoxy)methylene]-5-(3'-chloroquinolin - 4'-yl)]propane] and racemic trans-[Formule :C16H14Cl2ODegré de pureté :Min. 95%Masse moléculaire :293.2 g/mol(2R,2R,Cis)-saxagliptin
CAS :(2R,2R,Cis)-saxagliptin is an analytical research and development (R&D) drug development API impurity HPLC standard that is a metabolite of saxagliptin. Saxagliptin is a drug product that has been approved for the treatment of type 2 diabetes. It has been shown to inhibit the activity of dipeptidyl peptidase-4 (DPP-4) in vitro and in vivo. Saxagliptin is a competitive inhibitor of DPP-4, which prevents it from breaking down incretin hormones such as glucagon-like peptide 1 (GLP-1). This results in increased levels of GLP-1, which improves blood glucose control. The purity level for this API impurity HPLC standard is high. Impurities are less than 0.5% and have been tested at various concentrations to ensure quality standards are met.Formule :C18H25N3O2Degré de pureté :Min. 95%Masse moléculaire :315.40 g/mol
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