APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.317 produits)
- Anthraquinones et Dérivés(402 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.383 produits)
- Dérivés des Benzodiazépines(324 produits)
- Glucides et Glycoconjugués(5.045 produits)
- Esters et Dérivés(42.241 produits)
- Acides Gras et Dérivés Lipidiques(32.368 produits)
- Flavonoïdes et Polyphénols(17.070 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(210 produits)
- Cétones et Dérivés(2.394 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.310 produits)
- Nitriles et Dérivés Cyano(3.068 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.427 produits)
- Phosphates et Phosphonates Organiques(1.193 produits)
- Sulfonates et Sulfates Organiques(10.416 produits)
- Composés Organométalliques(4.417 produits)
- Autres(6.266 produits)
- Peptides et Protéines(3.130 produits)
- Polymères et Dérivés(99 produits)
- Dérivés des Purines et Pyrimidines(8.893 produits)
- Dérivés de Quinazoline et de Quinoléine(65.624 produits)
- Quinones et Dérivés(24.336 produits)
- Sels et Dérivés d’API(81.450 produits)
- Stéroïdes et Dérivés(4.911 produits)
- Sulfamides et Dérivés(2.556 produits)
- Terpénoïdes et Dérivés(3.830 produits)
- Thiazolidinediones et Thiopyranes(2.752 produits)
- Composés β-Adrénergiques(227 produits)
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58824 produits trouvés pour "APIs pour la recherche et les impuretés"
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N-9H-Fluoren-2-yl-N-hydroxy-acetamide
CAS :N-9H-Fluoren-2-yl-N-hydroxyacetamide is a prodrug that is hydrolyzed in vivo to form 2-(2,6-dichloro-4-(p-nitrophenoxy)phenoxy)-N,N-dimethylethylene diamine (N,9H-diiodofluorene). N,9H-diiodofluorene is an active metabolite that inhibits the activity of the enzyme glutamate dehydrogenase. This inhibition leads to accumulation of ammonia and cell death. N,9H Diiodofluorene has been shown to inhibit the growth of typhimurium in vitro.Formule :C15H13NO2Degré de pureté :Min. 95%Masse moléculaire :239.27 g/mol24(R/S),25-Epoxycholesterol-d6
CAS :Produit contrôlé24(R/S),25-Epoxycholesterol-d6 is an analytical reference standard used as a secondary metabolite in drug development. It is also used as a high purity HPLC standard and an impurity standard in pharmacopoeia. 24(R/S),25-Epoxycholesterol-d6 is a natural product that can be synthesized or obtained from natural sources such as soybeans, bovine liver, and fish oil. Pharmacopoeia grade 24(R/S),25-Epoxycholesterol-d6 is typically custom synthesized to meet the needs of drug development and production.Formule :C27H38O2D6Degré de pureté :Min. 95%Masse moléculaire :406.67 g/mol2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid 2-carboxyphenyl ester
CAS :2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid 2-carboxyphenyl ester is a synthetic compound that has anti-inflammatory and anti-cancer properties. It inhibits the production of prostaglandins by inhibiting phospholipase A2, which leads to an increase in cyclooxygenase levels. This may be due to the inhibition of the enzyme's activity or its induction by other compounds. The drug also has cytostatic and cytotoxic effects on cancer cells. It is used for the treatment of muscle spasms, hepatitis, cancer, skin cancers and autoimmune diseases. 2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid 2-carboxyphenyl ester is administered transdermally or systemically.Formule :C23H16O8Degré de pureté :Min. 95%Masse moléculaire :420.4 g/molMontelukast impurity I
CAS :Montelukast impurity I is an impurity found in the drug product, Montelukast. It is a natural substance and is produced as a result of metabolism studies. The chemical name for this impurity is 3-hydroxy-4-(2-methylpropyl)-5-(4-methoxyphenyl)pentanoic acid. This impurity can be used as an analytical standard and can be synthesized for use in pharmacopoeia. This compound has not been shown to have any therapeutic effects on humans or animals. This impurity has been shown to cause nausea, vomiting, and diarrhea in some patients.
Formule :C35H36ClNO4SDegré de pureté :Min. 95%Masse moléculaire :602.18 g/molDi-p-tolyl-phosphate-d14
CAS :Di-p-tolyl-phosphate is a toxic chemical that belongs to the methyl ester class. It can be found in polymers, plasticizers, and paints. Di-p-tolyl-phosphate is used as a plasticizer in polyvinyl chloride (PVC) and polyurethane products. It has been shown to cause paralysis of insects, which may be due to its ability to inhibit the enzyme acetylcholinesterase. Di-p-tolyl-phosphate has also been shown to have acute toxicity in mice, with LD50 values of 0.5 g/kg for males and 0.6 g/kg for females. The mechanism of toxicity may be due to its ability to inhibit the synthesis of acetylcholine, a neurotransmitter that stimulates muscle contraction. This inhibition leads to paralysis that is eventually followed by death from respiratory failure.Formule :C14H15O4PDegré de pureté :Min. 95%Masse moléculaire :278.24 g/molCis-1,2-dihydroperillic acid
CAS :Cis-1,2-dihydroperillic acid is an endogenous metabolite of perillyl alcohol. It is formed in the liver from perillyl alcohol and is excreted in the urine. Cis-1,2-dihydroperillic acid has been shown to inhibit cell growth and induce cancer in animals and humans. Its mechanism of action may be due to its ability to inhibit the production of a growth factor called growth factor β (GFβ). This hormone stimulates the proliferation of mammary carcinomas and may also be involved in carcinogenesis. Cis-1,2-dihydroperillic acid is present in plasma at low concentrations, which have been measured using a human bioassay.
Formule :C10H16O2Degré de pureté :Min. 95%Masse moléculaire :168.23 g/molAripiprazole dimer
CAS :Aripiprazole dimer is a drug product that is used for analytical purposes. It is an impurity standard for the research and development of drugs. The CAS number for this compound is 1797986-18-5. This compound, which has been synthesized, has not been found in nature and does not occur in pure form. Aripiprazole dimer is an analytical impurity standard and has been shown to be metabolized by CYP3A4. It also exhibits high purity levels and can be used as an API impurity standard in pharmacopoeia guidelines.Formule :C48H56Cl4N6O4Degré de pureté :Min. 95%Masse moléculaire :922.81 g/mol9-b-D-Arabinofuranosyl-6-chloro-9H-purin-2-amine
CAS :9-b-D-Arabinofuranosyl-6-chloro-9H-purin-2-amine is a synthetic compound that has been used as an impurity standard for the drug product. It has been shown to possess immunosuppressive and antitumor effects in animal models. 9bADAP has also been found to have antiinflammatory properties and may be useful for the treatment of autoimmune diseases. Metabolism studies have shown that it is metabolized by CYP450 enzymes, including CYP1A2, CYP2C8, CYP2D6, and CYP3A4. The major metabolites are 9-(N9)-methyladenine, adenine, and 6-(N9)-methyladenine.Formule :C10H12ClN5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :301.69 g/mol4'-[(4'Methyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid
CAS :Gatifloxacin is a fluoroquinolone antibiotic that inhibits the DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Gatifloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Gatifloxacin has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. 4'-[(4'Methyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][Formule :C32H28N4O2Degré de pureté :Min. 95%Masse moléculaire :500.59 g/mol(2R,2R,Cis)-saxagliptin
CAS :(2R,2R,Cis)-saxagliptin is an analytical research and development (R&D) drug development API impurity HPLC standard that is a metabolite of saxagliptin. Saxagliptin is a drug product that has been approved for the treatment of type 2 diabetes. It has been shown to inhibit the activity of dipeptidyl peptidase-4 (DPP-4) in vitro and in vivo. Saxagliptin is a competitive inhibitor of DPP-4, which prevents it from breaking down incretin hormones such as glucagon-like peptide 1 (GLP-1). This results in increased levels of GLP-1, which improves blood glucose control. The purity level for this API impurity HPLC standard is high. Impurities are less than 0.5% and have been tested at various concentrations to ensure quality standards are met.Formule :C18H25N3O2Degré de pureté :Min. 95%Masse moléculaire :315.40 g/molPantoprazole impurity
CAS :Pantoprazole is a proton pump inhibitor. It is used in the treatment of gastroesophageal reflux disease and other conditions involving excessive stomach acid production. The chemical name for Pantoprazole impurity is (E)-1-(4-chlorophenyl)ethyl-3-[(pyrrolidin-2-yl)oxy]propanediol. This substance is an enantiomer of pantoprazole, which has been determined to be inactive. Pantoprazole impurity can be identified by its melting point, crystallizing habit, and optical rotation. Active carbon filtration can be used to remove this substance from the final product.Formule :C24H24F2N4O5SDegré de pureté :Min. 95%Masse moléculaire :518.53 g/molAmino albendazole sulfone
CAS :Amino albendazole sulfone is an anthelmintic drug that is used to treat worm infestations in animals. It is the active metabolite of fenbendazole sulfone and has a terminal half-life of 12 hours in humans. Amino albendazole sulfone can be prepared by chromatographic methods, such as liquid chromatography or gas chromatography, and it can be analyzed with a fluorescence detector. This drug has been shown to have a concentration–time curve following administration to rats and results in an increase in the number of worms eliminated from the body.Formule :C10H13N3O2SDegré de pureté :Min. 95%Masse moléculaire :239.3 g/molVitalethine
CAS :Vitalethine is a protein analog that has been shown to induce apoptosis in cancer cells. It acts as a kinase inhibitor and specifically targets the hepcidin pathway, which is involved in tumor growth and metastasis. Vitalethine has been tested on human cancer cell lines and has shown potent anticancer activity. This protein analog may have potential therapeutic applications for the treatment of various types of cancers. Vitalethine can be detected in urine samples and may serve as a biomarker for cancer diagnosis and monitoring.
Formule :C12H22N4O6S2Degré de pureté :Min. 95%Masse moléculaire :382.5 g/mol4-Carboxy nevirapine
CAS :4-Carboxy nevirapine is a synthetic drug product that is used as an analytical reference standard for the impurity 4-carboxynevirapine. It has been shown to have niche applications in pharmacopoeia and natural product research and development. The metabolite 4-carboxynevirapine can be synthesized from nevirapine which is found in the plant Cinchona officinalis. This metabolite has been extensively studied for its role in the metabolism of nevirapine and its possible therapeutic applications, such as its ability to inhibit HIV replication.Formule :C15H12N4O3Degré de pureté :Min. 95%Masse moléculaire :296.28 g/molDexamethasone EP Impurity K
CAS :Produit contrôléDexamethasone EP Impurity K is an analytical standard for impurities in the drug product Dexamethasone EP. It is a synthetic methanolic solution of dexamethasone and a metabolite, which is chemically identical to the natural form. The purity of this impurity standard is 99.9%. This synthetic impurity is used for HPLC analysis as a pharmacopoeia-grade reference material.Formule :C22H26O4Degré de pureté :Min. 95%Masse moléculaire :354.44 g/mol(-)-Tianeptine monosodium salt
CAS :Produit contrôlé(-)-Tianeptine monosodium salt is a potent inhibitor of kinase activity that has shown anticancer properties in human urine. It has been found to inhibit the growth of cancer cells by inducing apoptosis, which is programmed cell death. (-)-Tianeptine monosodium salt also inhibits the activity of kinases, which are enzymes that regulate various cellular processes such as protein synthesis and cell division. This compound has been studied extensively for its potential use as an anticancer drug and has shown promising results in Chinese hamster ovary cells. In addition, it has been found to be a potent inhibitor of D-xylose kinase, which may have implications for the treatment of certain metabolic disorders. Overall, (-)-Tianeptine monosodium salt shows great potential as an effective inhibitor of cancer cell growth and other diseases related to kinase activity.Formule :C21H25ClN2O4SDegré de pureté :Min. 95%Masse moléculaire :437 g/molMirtazapine N-oxide
CAS :Mirtazapine N-oxide is an antidepressant agent that is metabolized to mirtazapine. Mirtazapine N-oxide has been shown to have a linear response in the detection of serotonin in urine samples and has been used for pharmacokinetic studies, optimization, and clinical use. The enantiomer of mirtazapine N-oxide has been shown to be more potent than the racemic mixture. The drug is excreted unchanged into the urine with a half-life of 2 hours. Mirtazapine N-oxide can be detected in plasma for up to 24 hours after oral administration and may accumulate in certain tissues such as liver or kidney. This drug has also been shown to cause death in mice at very high doses.Formule :C17H19N3ODegré de pureté :Min. 95%Masse moléculaire :281.35 g/molBLM-IN-1
CAS :Please enquire for more information about BLM-IN-1 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C28H35FN4ODegré de pureté :Min. 95%Masse moléculaire :462.6 g/molFimaporfin
CAS :Fimaporfin is an analog of hepcidin, a protein found in urine that regulates iron metabolism. It is a kinase inhibitor that induces apoptosis in cancer cells. Fimaporfin has shown promising results as an anticancer agent and has been tested against various types of tumors in human and animal models. This drug targets kinases involved in cancer cell proliferation and survival, inhibiting their activity and inducing cancer cell death through apoptosis. Fimaporfin has been shown to be effective against Chinese hamster ovary cells, as well as other human cancer cell lines. This drug holds great promise for the treatment of cancer and may prove to be a valuable addition to current anticancer therapies.Formule :C132H96N12O18S6Degré de pureté :Min. 95%Masse moléculaire :2,330.6 g/molBIM 23052
CAS :BIM 23052 is an analog kinase inhibitor that has been shown to have potent anticancer activity. It targets specific proteins in cancer cells and induces apoptosis, leading to cell death. BIM 23052 has been tested extensively in human urine and Chinese hamster ovary cells, demonstrating its effectiveness against a wide range of tumor types. This medicinal compound inhibits several kinases involved in cancer progression, making it a promising candidate for the treatment of various cancers. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.Formule :C61H75N11O10Degré de pureté :Min. 95%Masse moléculaire :1,122.3 g/mol
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