APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.316 produits)
- Anthraquinones et Dérivés(402 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.375 produits)
- Dérivés des Benzodiazépines(323 produits)
- Glucides et Glycoconjugués(5.038 produits)
- Esters et Dérivés(42.239 produits)
- Acides Gras et Dérivés Lipidiques(32.360 produits)
- Flavonoïdes et Polyphénols(17.066 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(208 produits)
- Cétones et Dérivés(2.393 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.307 produits)
- Nitriles et Dérivés Cyano(3.068 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.409 produits)
- Phosphates et Phosphonates Organiques(1.192 produits)
- Sulfonates et Sulfates Organiques(10.415 produits)
- Composés Organométalliques(4.417 produits)
- Autres(6.257 produits)
- Peptides et Protéines(3.129 produits)
- Polymères et Dérivés(99 produits)
- Dérivés des Purines et Pyrimidines(8.889 produits)
- Dérivés de Quinazoline et de Quinoléine(65.574 produits)
- Quinones et Dérivés(24.334 produits)
- Sels et Dérivés d’API(81.516 produits)
- Stéroïdes et Dérivés(4.905 produits)
- Sulfamides et Dérivés(2.539 produits)
- Terpénoïdes et Dérivés(3.827 produits)
- Thiazolidinediones et Thiopyranes(2.752 produits)
- Composés β-Adrénergiques(227 produits)
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58881 produits trouvés pour "APIs pour la recherche et les impuretés"
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2,2',4,4',5,6'-Hexachlorobiphenyl
CAS :Produit contrôlé2,2',4,4',5,6'-Hexachlorobiphenyl (PCB-153) is a potent inhibitor of kinases and has been shown to induce apoptosis in tumor cells. It is an analog of medicinal inhibitors used for the treatment of cancer. PCB-153 has been tested on both Chinese hamster ovary cells and human cancer cell lines and has demonstrated its anticancer properties by inhibiting protein kinase activity. In addition, it has been found in urine samples from individuals with cancer, suggesting that it may play a role in the development or progression of this disease. The potential therapeutic benefits of PCB-153 as an anticancer agent are currently being investigated.
Formule :C12H4Cl6Degré de pureté :Min. 95%Masse moléculaire :360.9 g/molFensulfothion Oxon Sulfide
CAS :Fensulfothion oxon sulfide is a drug product that can be used as an analytical reference material. It has been shown to be metabolized in animal studies. The metabolite, fensulfothion sulfoxide, can be synthesized from fensulfothion oxon sulfide and is a standard impurity in the synthetic process. Fensulfothion oxon sulfide is used in drug development and research and development to establish pharmacopoeia standards for HPLC purity requirement.Formule :C11H17O4PSDegré de pureté :Min. 95%Masse moléculaire :276.29 g/mol1-Benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate
CAS :Please enquire for more information about 1-Benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C20H27NO4SDegré de pureté :Min. 95%Masse moléculaire :377.5 g/mol9-b-D-Arabinofuranosyl-6-chloro-9H-purin-2-amine
CAS :9-b-D-Arabinofuranosyl-6-chloro-9H-purin-2-amine is a synthetic compound that has been used as an impurity standard for the drug product. It has been shown to possess immunosuppressive and antitumor effects in animal models. 9bADAP has also been found to have antiinflammatory properties and may be useful for the treatment of autoimmune diseases. Metabolism studies have shown that it is metabolized by CYP450 enzymes, including CYP1A2, CYP2C8, CYP2D6, and CYP3A4. The major metabolites are 9-(N9)-methyladenine, adenine, and 6-(N9)-methyladenine.Formule :C10H12ClN5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :301.69 g/mol2,3,3',4'-Tetrachlorobiphenyl
CAS :Produit contrôlé2,3,3',4'-Tetrachlorobiphenyl is an inhibitor that has been shown to induce apoptosis in human and Chinese hamster cancer cells. It inhibits the activity of kinases, which are enzymes that play a critical role in regulating cell growth and division. The inhibition of these enzymes leads to the activation of apoptotic pathways, resulting in cell death. Additionally, 2,3,3',4'-Tetrachlorobiphenyl has been found to inhibit the uptake of d-xylose by cells and decrease protein synthesis. This compound has potential medicinal applications for the treatment of tumors and cancers. It can be detected in urine samples and is considered a marker for exposure to environmental pollutants.Formule :C12H6Cl4Degré de pureté :Min. 95%Masse moléculaire :292 g/mol3,4-Difluoro-2-(trifluoromethyl)-benzenamine
CAS :Please enquire for more information about 3,4-Difluoro-2-(trifluoromethyl)-benzenamine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C7H4F5NDegré de pureté :Min. 95%Masse moléculaire :197.1 g/molGlimepiride EP Impurity G
Please enquire for more information about Glimepiride EP Impurity G including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C19H25N3O6SDegré de pureté :Min. 95%Masse moléculaire :423.48 g/molDiclazuril 6-carboxylic acid [(4-chlorophenyl)cyanomethyl]-2,6-dichlorophenyl-4-amide
CAS :Diclazuril is a drug product that is custom synthesized in our laboratory. It is a high purity, analytical standard with a CAS No. 1796928-69-2. Diclazuril is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The natural form of diclazuril has been identified as the metabolite of clozapine and other antipsychotic drugs. This drug has been evaluated for its pharmacopoeia and HPLC standards. These standards are used to determine the quality and purity of drugs that are used in research and development.Formule :C32H16Cl6N6O3Degré de pureté :Min. 95%Masse moléculaire :745.2 g/mol(2R,2R,Cis)-saxagliptin
CAS :(2R,2R,Cis)-saxagliptin is an analytical research and development (R&D) drug development API impurity HPLC standard that is a metabolite of saxagliptin. Saxagliptin is a drug product that has been approved for the treatment of type 2 diabetes. It has been shown to inhibit the activity of dipeptidyl peptidase-4 (DPP-4) in vitro and in vivo. Saxagliptin is a competitive inhibitor of DPP-4, which prevents it from breaking down incretin hormones such as glucagon-like peptide 1 (GLP-1). This results in increased levels of GLP-1, which improves blood glucose control. The purity level for this API impurity HPLC standard is high. Impurities are less than 0.5% and have been tested at various concentrations to ensure quality standards are met.Formule :C18H25N3O2Degré de pureté :Min. 95%Masse moléculaire :315.40 g/molAmino albendazole sulfone
CAS :Amino albendazole sulfone is an anthelmintic drug that is used to treat worm infestations in animals. It is the active metabolite of fenbendazole sulfone and has a terminal half-life of 12 hours in humans. Amino albendazole sulfone can be prepared by chromatographic methods, such as liquid chromatography or gas chromatography, and it can be analyzed with a fluorescence detector. This drug has been shown to have a concentration–time curve following administration to rats and results in an increase in the number of worms eliminated from the body.Formule :C10H13N3O2SDegré de pureté :Min. 95%Masse moléculaire :239.3 g/molGriseofulvic acid
CAS :Griseofulvic acid is a molecule that encompasses an acidic chromatographic and plasma samples, urine metabolite, monocarboxylic acid, water molecule, pharmaceutical preparations, molecule, cancer and hyperproliferative. Griseofulvic acid is used for the treatment of autoimmune diseases and cancers. In addition to its use as an anticancer drug, griseofulvic acid has been shown to have immunosuppressive effects in cell cultures. The mechanism of action of griseofulvic acid in this regard may be due to its ability to disrupt DNA synthesis by binding to the purine bases in RNA and DNA molecules.Formule :C16H15ClO6Degré de pureté :Min. 95%Masse moléculaire :338.74 g/molNascopine
CAS :Nascopine is an analog of nifedipine that acts as a potent inhibitor of protein kinases. It has been shown to induce apoptosis in human cancer cells and inhibit the growth of tumors in Chinese hamsters. Nascopine is an anticancer drug that works by blocking the activity of kinases, which play a crucial role in cancer cell proliferation and survival. This drug has been found to be effective against a wide range of cancers, including breast, prostate, and lung cancer. In addition, Nascopine has been found in urine samples from cancer patients undergoing treatment with this drug. Its unique mechanism of action makes it a promising candidate for further development as an anticancer therapy.
Formule :C22H23NO7Degré de pureté :Min. 95%Masse moléculaire :413.4 g/molN-Acetyl-L-cystine
CAS :N-Acetyl-L-cystine is a water soluble amino acid that has been approved for treatment of cystic fibrosis in adults and children older than six years. It is available as an aerosol, nebulized solution or oral capsule. N-Acetyl-L-cystine has been shown to have a protective effect against influenza virus (Virus A) infection by reducing the proinflammatory cytokines and reactive oxygen species in response to the virus. This drug also reduces the severity of symptoms associated with influenza virus infection. The pharmacokinetic properties of this drug are well understood, as it is stable in vivo, crosses the blood brain barrier, and does not bind to serum proteins.Formule :C8H14N2O5S2Degré de pureté :Min. 95%Masse moléculaire :282.3 g/molRiboflavin 4',5'-diphosphate
CAS :Riboflavin 4',5'-diphosphate is a yellow crystalline powder that is soluble in water and has a molecular weight of 238.1. It is used as an analytical standard, Research and Development (R&D) and Drug development (DD) impurity in HPLC, as well as an impurity standard for pharmacopoeia. Riboflavin 4',5'-diphosphate can also be used to synthesize riboflavin 5'-phosphate, which is a metabolite of riboflavin. Riboflavin 4',5'-diphosphate exhibits high purity with no detectable amounts of impurities or degradation products.Formule :C17H22N4O12P2Degré de pureté :Min. 95%Masse moléculaire :536.3 g/molDexamethasone EP Impurity K
CAS :Produit contrôléDexamethasone EP Impurity K is an analytical standard for impurities in the drug product Dexamethasone EP. It is a synthetic methanolic solution of dexamethasone and a metabolite, which is chemically identical to the natural form. The purity of this impurity standard is 99.9%. This synthetic impurity is used for HPLC analysis as a pharmacopoeia-grade reference material.Formule :C22H26O4Degré de pureté :Min. 95%Masse moléculaire :354.44 g/molPerindopril acyl-b-D-glucuronide
CAS :Metabolite of perindoprilFormule :C25H40N2O11Degré de pureté :Min. 95%Couleur et forme :Off-white or pale yellow solid.Masse moléculaire :544.6 g/mol(-)-Tianeptine monosodium salt
CAS :Produit contrôlé(-)-Tianeptine monosodium salt is a potent inhibitor of kinase activity that has shown anticancer properties in human urine. It has been found to inhibit the growth of cancer cells by inducing apoptosis, which is programmed cell death. (-)-Tianeptine monosodium salt also inhibits the activity of kinases, which are enzymes that regulate various cellular processes such as protein synthesis and cell division. This compound has been studied extensively for its potential use as an anticancer drug and has shown promising results in Chinese hamster ovary cells. In addition, it has been found to be a potent inhibitor of D-xylose kinase, which may have implications for the treatment of certain metabolic disorders. Overall, (-)-Tianeptine monosodium salt shows great potential as an effective inhibitor of cancer cell growth and other diseases related to kinase activity.Formule :C21H25ClN2O4SDegré de pureté :Min. 95%Masse moléculaire :437 g/molMirtazapine N-oxide
CAS :Mirtazapine N-oxide is an antidepressant agent that is metabolized to mirtazapine. Mirtazapine N-oxide has been shown to have a linear response in the detection of serotonin in urine samples and has been used for pharmacokinetic studies, optimization, and clinical use. The enantiomer of mirtazapine N-oxide has been shown to be more potent than the racemic mixture. The drug is excreted unchanged into the urine with a half-life of 2 hours. Mirtazapine N-oxide can be detected in plasma for up to 24 hours after oral administration and may accumulate in certain tissues such as liver or kidney. This drug has also been shown to cause death in mice at very high doses.Formule :C17H19N3ODegré de pureté :Min. 95%Masse moléculaire :281.35 g/mol2-Dodecenol
CAS :2-Dodecenol is an analog of a natural compound found in Chinese medicinal herbs. This compound has been shown to have potent anticancer activity against various cancer cell lines, including human tumor cells. 2-Dodecenol has been found to inhibit the activity of kinases, which are enzymes that play a key role in regulating cell growth and proliferation. It also induces apoptosis, which is programmed cell death, in cancer cells. In addition, this compound has been shown to be a potent inhibitor of protein synthesis in cancer cells. Studies have demonstrated that 2-Dodecenol can inhibit the growth of tumors and reduce their size in animal models. This compound has shown promise as a potential therapeutic agent for the treatment of various types of cancer.Formule :C12H24ODegré de pureté :Min. 95%Masse moléculaire :184.32 g/mol1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyl-1-propanone
CAS :1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyl-1-propanone is a metabolite that is formed from the drug product. It is a synthetic compound that has been shown to have anti-inflammatory and analgesic activities in animal models. 1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyll -1-propanone has been shown to be effective against carrageenan, Freund's adjuvant, and Complete Freund's Adjuvant induced arthritis in rats. This metabolite also inhibits prostaglandin synthesis, which may contribute to its anti-inflammatory effects.Formule :C18H20O4Degré de pureté :Min. 95%Masse moléculaire :300.35 g/mol
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