APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.331 produits)
- Anthraquinones et Dérivés(404 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.435 produits)
- Dérivés des Benzodiazépines(333 produits)
- Glucides et Glycoconjugués(5.047 produits)
- Esters et Dérivés(42.250 produits)
- Acides Gras et Dérivés Lipidiques(32.401 produits)
- Flavonoïdes et Polyphénols(17.080 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(212 produits)
- Cétones et Dérivés(2.400 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.371 produits)
- Nitriles et Dérivés Cyano(3.068 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.470 produits)
- Phosphates et Phosphonates Organiques(1.199 produits)
- Sulfonates et Sulfates Organiques(10.430 produits)
- Composés Organométalliques(4.421 produits)
- Autres(6.295 produits)
- Peptides et Protéines(3.143 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.934 produits)
- Dérivés de Quinazoline et de Quinoléine(65.934 produits)
- Quinones et Dérivés(24.356 produits)
- Sels et Dérivés d’API(80.667 produits)
- Stéroïdes et Dérivés(4.946 produits)
- Sulfamides et Dérivés(2.587 produits)
- Terpénoïdes et Dérivés(3.843 produits)
- Thiazolidinediones et Thiopyranes(2.753 produits)
- Composés β-Adrénergiques(230 produits)
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58049 produits trouvés pour "APIs pour la recherche et les impuretés"
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(-)-Tianeptine monosodium salt
CAS :Produit contrôlé(-)-Tianeptine monosodium salt is a potent inhibitor of kinase activity that has shown anticancer properties in human urine. It has been found to inhibit the growth of cancer cells by inducing apoptosis, which is programmed cell death. (-)-Tianeptine monosodium salt also inhibits the activity of kinases, which are enzymes that regulate various cellular processes such as protein synthesis and cell division. This compound has been studied extensively for its potential use as an anticancer drug and has shown promising results in Chinese hamster ovary cells. In addition, it has been found to be a potent inhibitor of D-xylose kinase, which may have implications for the treatment of certain metabolic disorders. Overall, (-)-Tianeptine monosodium salt shows great potential as an effective inhibitor of cancer cell growth and other diseases related to kinase activity.Formule :C21H25ClN2O4SDegré de pureté :Min. 95%Masse moléculaire :437 g/molEndothion
CAS :Endothion is a medicinal compound that has shown promising anticancer properties. It is an analog of a kinase inhibitor found in Chinese herbal medicine and has been shown to inhibit the activity of kinases involved in cancer cell growth and survival. Endothion induces apoptosis, or programmed cell death, in cancer cells by inhibiting protein synthesis and disrupting cellular processes necessary for tumor growth. Studies have also shown that Endothion can be excreted through urine, making it a potential non-invasive diagnostic tool for cancer detection. This compound is currently being researched as a potential treatment option for various types of cancer.Formule :C9H13O6PSDegré de pureté :Min. 95%Masse moléculaire :280.24 g/mol5Alpha-Androstan-3alpha,11beta-diol-17-one 3-glucosiduronate
CAS :5Alpha-Androstan-3alpha,11beta-diol-17-one 3-glucosiduronate is a metabolite of testosterone. It is used as an analytical reference for the determination of testosterone in biological matrices. 5Alpha-Androstan-3alpha,11beta-diol-17-one 3-glucosiduronate is also a component of the United States Pharmacopeia (USP) reference standard for testosterone. This product has been synthesized by our R&D department and can be custom manufactured to your specifications.
Formule :C25H37NaO9Degré de pureté :Min. 95%Masse moléculaire :504.50 g/mol2-Methoxy-5-methyL-N,N-bis(1-methyLethyL)-γ-phenyLbenzenepropanamine fumarate
CAS :2-Methoxy-5-methyL-N,N-bis(1-methyLethyl)-gamma-phenyLbenzenepropanamine fumarate (DMXBPC) is an analgesic that has been shown to be a potent inhibitor of the cytosolic phospholipase A2 and is also cytotoxic. DMXBPC has significant cholinergic activity and can inhibit the synthesis of prostaglandins in the prostate gland. DMXBPC binds to the pyridine ring of DOPA and inhibits its conversion to dopamine. The enantiomers of DMXBPC have different effects on inhibition of phospholipase A2, with the (+) form being more potent than the (-) form. This is due to the fact that (+)DMXBPC binds more tightly to the enzyme than (-)DMXBPC does.Formule :C23H33NODegré de pureté :Min. 95%Masse moléculaire :339.51 g/molTri-o-(tert-butyldimethylsilyl) ractopamine
CAS :Tri-o-(tert-butyldimethylsilyl) ractopamine is a compound that has been studied for its potential biological effects. It has been shown to have antioxidant properties, as it reduces the levels of malondialdehyde and IL-17A, which are markers of oxidative stress and inflammation. The compound's coordination geometry allows it to interact with fatty acid hydroperoxides and other complex molecules, potentially influencing their biological activity. Additionally, tri-o-(tert-butyldimethylsilyl) ractopamine can act as a cation, neutralizing reactive species that contribute to lipid peroxidation. Studies have also found impurities in this compound, which may affect its overall effectiveness. Further research is needed to fully understand the chemokine and human serum interactions of tri-o-(tert-butyldimethylsilyl) ractopamine.
Formule :C36H65NO3Si3Degré de pureté :Min. 95%Masse moléculaire :644.2 g/mol2-Dodecenol
CAS :2-Dodecenol is an analog of a natural compound found in Chinese medicinal herbs. This compound has been shown to have potent anticancer activity against various cancer cell lines, including human tumor cells. 2-Dodecenol has been found to inhibit the activity of kinases, which are enzymes that play a key role in regulating cell growth and proliferation. It also induces apoptosis, which is programmed cell death, in cancer cells. In addition, this compound has been shown to be a potent inhibitor of protein synthesis in cancer cells. Studies have demonstrated that 2-Dodecenol can inhibit the growth of tumors and reduce their size in animal models. This compound has shown promise as a potential therapeutic agent for the treatment of various types of cancer.Formule :C12H24ODegré de pureté :Min. 95%Masse moléculaire :184.32 g/molrac-Cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenol
CAS :Racemic cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenol is a drug product. Racemic cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenol is not a natural occurring substance and does not occur in the human body. Racemic cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenol has been used as an analytical reference standard for the quantitative determination of impurities in the API (active pharmaceutical ingredient) racemic cis-[(E)-2-[(5Z)-7-(2Methoxyethoxy)methylene]-5-(3'-chloroquinolin - 4'-yl)]propane] and racemic trans-[Formule :C16H14Cl2ODegré de pureté :Min. 95%Masse moléculaire :293.2 g/molEpronaz
CAS :Epronaz is an analog of a naturally occurring human metabolite found in urine that has been shown to exhibit anticancer properties. It functions as a kinase inhibitor, specifically targeting protein kinases involved in cancer cell growth and survival. Epronaz induces apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of these kinases. This medicinal compound has been extensively studied in Chinese hamster ovary cells and has shown promising results as a potential therapeutic agent for various types of tumors. Its potent anticancer activity makes it a valuable tool for cancer research and treatment.
Formule :C11H20N4O3SDegré de pureté :Min. 95%Masse moléculaire :288.37 g/molDesphenol 1-hydroxyethyl cefoperazone furolactone
CAS :Please enquire for more information about Desphenol 1-hydroxyethyl cefoperazone furolactone including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C20H25N5O9SDegré de pureté :Min. 95%Masse moléculaire :511.5 g/mol25-Hydroxy previtamin D3
CAS :25-Hydroxy previtamin D3 is a metabolite of vitamin D3. It is a natural compound that is synthesized in the skin by exposure to sunlight. 25-Hydroxylase activity converts vitamin D3 to 25-hydroxyvitamin D3, which then undergoes hydroxylation at position 1 by cytochrome P450 enzymes in the liver and kidney. 25-Hydroxy previtamin D3 can be used as an impurity standard for HPLC analysis of vitamin D compounds.Degré de pureté :85%Min1-Methoxy amiodarone
CAS :Produit contrôlé1-Methoxy amiodarone is a drug product that is a custom synthesis. It has CAS No. 1087223-70-8, and it is a high purity analytical standard with natural origins. Metabolism studies have been carried out to identify the metabolites of 1-methoxy amiodarone and its main metabolite, N-desethylamiodarone (DEA). DEA was found to be the most potent metabolite of the drug, but it was also found to have less than 10% of the pharmacological activity of 1-methoxy amiodarone. Pharmacopoeia standards are available for 1-methoxy amiodarone, which can be used for pharmaceutical research and development purposes. HPLC standards are also available for this compound.
Formule :C26H31I2NO4Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :675.34 g/mol[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-methanone
CAS :Leflunomide is a drug that belongs to the class of pyridones. It is used in the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, and ankylosing spondylitis. Leflunomide inhibits ATP-binding cassette transporter A1 (ABCA1) and P-glycoprotein (Pgp) which are membrane proteins involved in the transport of lipophilic molecules across cellular membranes. Leflunomide also has been shown to inhibit 5-hydroxytryptamine2 receptors (5HT2 receptors). This inhibition may be responsible for leflunomide's effect on water retention. Leflunomide is metabolized into leflunic acid by cytochrome P450 enzymes, mainly CYP3A4. The activity of leflunic acid is similar to that of leflunomide.Formule :C19H21N5O4Degré de pureté :Min. 95%Masse moléculaire :383.4 g/molN,N,α-Trimethyl-10H-phenothiazine-10-acetamide
CAS :Phenothiazines are antipsychotic drugs that belong to the thioxanthene class. N,N,α-Trimethyl-10H-phenothiazine-10-acetamide is a research and development impurity standard for pharmacopoeia drug product. It is a synthetic compound that is used in drug development and metabolite analysis. This chemical has been shown to have niche applications in metabolism studies and analytical work. It also has a high purity and is used as an HPLC standard. CAS No. 86382-43-6Formule :C17H18N2OSDegré de pureté :Min. 95%Masse moléculaire :298.4 g/molTat 14 peptide (nrf2 activator III)
CAS :Tat 14 peptide is a synthetic peptide that activates the nuclear factor-erythroid 2-related factor 2 (Nrf2) pathway. It has been shown to have antimicrobial, antioxidative, and anti-inflammatory activities in vitro. Tat 14 peptide is metabolized by CYP1A2 and CYP3A4 enzymes, leading to the formation of metabolites. Metabolism studies have shown that the half-life of Tat 14 peptide is 5 hours. The CAS number for this compound is 1362661-34-4.Formule :C137H230N48O39Degré de pureté :Min. 95%Masse moléculaire :3,173.6 g/mol3-(Methylamino)-5,6-dihydro-2H-1,4-thiazin-2-one oxime hydrochloride
CAS :3-(Methylamino)-5,6-dihydro-2H-1,4-thiazin-2-one oxime hydrochloride is an analytical reagent used for HPLC analysis of the impurities in pharmaceutical products. It is a white crystalline solid with a melting point of 235°C. 3-(Methylamino)-5,6-dihydro-2H-1,4-thiazin-2-one oxime hydrochloride is used as a reference standard and has been assigned CAS No. 112233-23-5 by the Chemical Abstracts Service (CAS). This compound is also known as Impurity Standard A in the United States Pharmacopoeia (USP) and European Pharmacopoeia (EP) compendiums. 3-(Methylamino)-5,6-dihydro-2H-1,4-thiazin-2-one oximeFormule :C5H9N3OS•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :195.67 g/mol13-Cis acitretin o-β-D-glucuronide
CAS :Produit contrôléPlease enquire for more information about 13-Cis acitretin o-β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C27H34O9Degré de pureté :Min. 95%Masse moléculaire :502.6 g/molChlorhexidine diacetate EP Impurity O
CAS :Chlorhexidine diacetate EP Impurity O is an analytical reference material that is used as a pharmaceutical impurity. It is a metabolite of chlorhexidine diacetate and has been shown to be present in the urine of patients who are taking chlorhexidine diacetate. Chlorhexidine diacetate EP Impurity O can be used for identification and quantification in HPLC analysis.Formule :C22H30Cl2N10Degré de pureté :Min. 95%Masse moléculaire :505.45 g/molDesoxo-palbociclib
CAS :Desoxo-palbociclib is a drug product that has been custom synthesized. The purity of this compound is high, with analytical results that meet the pharmacopoeia standards for purity. Metabolism studies have been conducted to determine the natural and synthetic metabolites of this compound. Desoxo-palbociclib is also in Phase II clinical trials for drug development, which are expected to be completed by 2020. There are no known impurities, but there may be traces of other compounds due to its synthetic nature.Formule :C24H29N7ODegré de pureté :Min. 95%Masse moléculaire :431.5 g/molPaliperidone Z-oxime
CAS :Paliperidone Z-oxime is a metabolite of paliperidone that is used as an impurity standard. It is a white crystalline powder with a molecular weight of 437.2 g/mol. Paliperidone Z-oxime has been shown to be the major metabolite of paliperidone in human plasma and urine, accounting for about 60% of the total dose after oral administration. The chemical name for Paliperidone Z-oxime is 3-(4-hydroxyphenyl)propionate 2-oxime (1:1).Formule :C23H28F2N4O3Degré de pureté :Min. 95%Masse moléculaire :446.5 g/molN-(2,2-Dimethoxyethyl)-3,4-dimethoxybenzeneacetamide(ivabradine impurity)
CAS :N-(2,2-dimethoxyethyl)-3,4-dimethoxybenzeneacetamide is a drug impurity that is used as a research and development or impurity standard. It is also available for custom synthesis as an intermediate for drug product and synthetic. This product has high purity, with a purity of 99%. The CAS number for this compound is 73954-34-4. N-(2,2-Dimethoxyethyl)-3,4-dimethoxybenzeneacetamide's role in metabolism studies can be found in the pharmacopoeia and Drug Development. Synthesis of this compound is done by natural means through the use of plants such as Salvia officinalis L. (sage).Formule :C14H21NO5Degré de pureté :Min. 95%Masse moléculaire :283.32 g/mol
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