APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.335 produits)
- Anthraquinones et Dérivés(405 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.456 produits)
- Dérivés des Benzodiazépines(334 produits)
- Glucides et Glycoconjugués(5.047 produits)
- Esters et Dérivés(42.252 produits)
- Acides Gras et Dérivés Lipidiques(32.417 produits)
- Flavonoïdes et Polyphénols(17.086 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(213 produits)
- Cétones et Dérivés(2.402 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.394 produits)
- Nitriles et Dérivés Cyano(3.068 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.486 produits)
- Phosphates et Phosphonates Organiques(1.201 produits)
- Sulfonates et Sulfates Organiques(10.436 produits)
- Composés Organométalliques(4.422 produits)
- Autres(6.310 produits)
- Peptides et Protéines(3.149 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.950 produits)
- Dérivés de Quinazoline et de Quinoléine(66.073 produits)
- Quinones et Dérivés(24.366 produits)
- Sels et Dérivés d’API(80.430 produits)
- Stéroïdes et Dérivés(4.963 produits)
- Sulfamides et Dérivés(2.603 produits)
- Terpénoïdes et Dérivés(3.851 produits)
- Thiazolidinediones et Thiopyranes(2.754 produits)
- Composés β-Adrénergiques(231 produits)
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57712 produits trouvés pour "APIs pour la recherche et les impuretés"
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Pseudomonic acid D sodium
CAS :Pseudomonic acid D sodium is a chemical compound that is found in coal tar. It has antimicrobial properties and can be used to inhibit the growth of bacteria and fungi. Pseudomonic acid D sodium has been shown to inhibit the growth of gram-positive bacterial strains, including Bacillus cereus, Clostridium perfringens, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus faecalis. It also inhibits the growth of yeast such as Candida albicans. Pseudomonic acid D sodium is soluble in water at low concentrations and insoluble in water at high concentrations. This chemical exhibits acidic properties with an acidic pH range from 2-4. Pseudomonic acid D sodium does not dissolve calcium carbonate or hydroxide solution due to its weakly acidic nature.Formule :C26H41NaO9Degré de pureté :Min. 95%Masse moléculaire :520.59 g/mol(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester
CAS :(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester is a synthetic molecule that is used as an analytical standard for HPLC. It is also used in the research and development of drugs. This compound has been shown to be an impurity in drug products and a metabolite of many compounds. (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4]-b]indole carboxylic acid methyl ester has a molecular weight of 372.64 grams per mole and theFormule :C22H19ClN2O5Degré de pureté :Min. 95%Masse moléculaire :426.8 g/mol9-Cis,13-cis-retinol 15-acetate-d5
CAS :Please enquire for more information about 9-Cis,13-cis-retinol 15-acetate-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C22H32O2Degré de pureté :Min. 95%Masse moléculaire :333.5 g/molErtapenem Ring Open Impurity
CAS :Ertapenem Ring Open Impurity is an impurity standard for research and development. It is a synthetic metabolite that is not present in the drug product. Ertapenem Ring Open Impurity is used as a standard to measure the purity of drugs, and it can be used as a reference material in pharmacopoeia and drug development. This impurity is also used in metabolism studies to determine the extent of conversion of ertapenem into its metabolites.Formule :C22H27N3O8SDegré de pureté :Min. 95%Masse moléculaire :493.53 g/molTicagrelor acetate
CAS :Ticagrelor is a drug that is used for the prevention of stroke and death in people who have had a recent heart attack. The active ingredient in this drug is ticagrelor acetate, which is an impurity standard. Ticagrelor acetate selectively binds to the P2Y12 receptor on platelets and blocks the ADP-induced activation of the receptor, preventing platelet aggregation. This chemical has been shown to reduce thrombus formation and improve survival rates after a heart attack. TICAGRELOR ACETATE: Ticagrelor is a drug that is used for the prevention of stroke and death in people who have had a recent heart attack. The active ingredient in this drug is ticagrelor acetate, which is an impurity standard. Ticagrelor acetate selectively binds to the P2Y12 receptor on platelets and blocks the ADP-induced activation of the receptor,Formule :C25H30F2N6O5SDegré de pureté :Min. 95%Masse moléculaire :564.6 g/mol(6S)-6-[Ethyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol
CAS :(6S)-6-[Ethyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol is a synthetic compound with a molecular weight of 310.9 g/mol and CAS number 1369625-04-6. This product is an impurity standard for the HPLC analysis of the drug product in order to ensure the quality of the active pharmaceutical ingredient. The purity is > 99% and the content is between 0.1% and 5%. (6S)-6-[Ethyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol has been shown to be metabolized in vitro by rat liver microsomes to 3-(2'-hydroxyethoxy)benzaldehyde (0.3%), 2-(4'-hydroxybutFormule :C18H23NOSDegré de pureté :Min. 95%Masse moléculaire :301.4 g/mol5''''-Methyl-apixaban
CAS :5''''-Methyl-apixaban is a drug product that is synthesized in the laboratory. It has been shown to be metabolized by cytochrome P450 enzymes, which are found in the liver, and eliminated by glucuronidation. This compound has been shown to have antiplatelet activity and is used for the prevention of stroke in patients with atrial fibrillation who cannot tolerate warfarin or those who need a higher dose of warfarin than can be achieved with standard doses. 5''''-Methyl-apixaban also inhibits platelet aggregation, leading to decreased blood clot formation. 5''''-Methyl-apixaban has been shown to have a number of metabolites including apixaban, which is formed through oxidation; apixanone, which is formed through hydrolysis; and apixanol, which is formed through conjugation with glucuronic acid. Apixanone has been shown to have more potent antiplatelet activityFormule :C26H27N5O4Degré de pureté :Min. 95%Masse moléculaire :473.5 g/molAmoxicillin EP Impurity C
CAS :Amoxicillin EP Impurity C is a metabolite of amoxicillin that is formed by oxidation. It can be used as an impurity standard for the detection of amoxicillin in HPLC and LC-MS analyses. Amoxicillin EP Impurity C has been found to be a natural metabolite of amoxicillin in human urine. This impurity also exhibits anti-inflammatory activity, which may be due to its ability to inhibit prostaglandin synthesis.Formule :C16H19N3O5SDegré de pureté :Min. 95%Masse moléculaire :365.4 g/molAmoxicillin EP Impurity D
CAS :Amoxicillin EP Impurity D is a metabolite of amoxicillin that is generated through the metabolism of the drug by enzymes in the body. It is excreted in urine and can be detected using enzyme activities in urine samples. Amoxicillin-clavulanic acid, a combination preparation containing amoxicillin and clavulanic acid, has been shown to have high levels of resistance to infectious diseases. Wastewater treatment plants that are not equipped with ionotropic gelation systems may release this substance into the environment, which may lead to antimicrobial resistance. Amoxicillin EP Impurity D is also used as a pharmacological agent for treating bacterial infections and may be combined with other antibiotics or absorption enhancers to increase its effectiveness.Formule :C16H21N3O6SDegré de pureté :Min. 95%Masse moléculaire :383.42 g/molVildagliptin related compound F
CAS :Vildagliptin related compound F (VRCF) is a drug product that has been custom synthesized. VRCF is a high purity, analytical standard. It is metabolized in the body and can be used as a research and development standard to study the metabolism of vildagliptin. VRCF is a natural metabolite that has been identified as an impurity in the drug product Vildagliptin. VRCF has not been recognized by the USP or EP for use as an impurity standard. CAS no: 1789703-36-1Formule :C17H24N2O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :304.4 g/molDabigatran impurity E
CAS :Produit contrôléDabigatran impurity E is a potent kinase inhibitor that has shown promising results in the field of cancer research. It is an analog of a Chinese medicinal herb that has been traditionally used to treat various ailments, including cancer. Dabigatran impurity E has been shown to induce apoptosis in human cancer cells by inhibiting the activity of specific kinases involved in cell replication and survival. This compound also exhibits anticancer properties by inhibiting the growth and proliferation of tumor cells. Additionally, Dabigatran impurity E has been found in urine samples from cancer patients, suggesting its potential as a biomarker for cancer diagnosis and monitoring. Overall, this compound holds great promise as a novel therapeutic agent for the treatment of various types of cancers.
Formule :C20H22N4O3Degré de pureté :Min. 95%Masse moléculaire :366.4 g/molMethotrexate-1-monomethyl ester
CAS :Methotrexate-1-monomethyl ester is an impurity found in methotrexate, a drug used to treat cancer and autoimmune disorders. Methotrexate-1-monomethyl ester is a white to off-white crystalline solid that has been synthesized as a custom synthesis. It is used as an analytical standard for the determination of methotrexate in biological fluids and tissues. The chemical purity of this compound can be determined by HPLC, which allows for the identification of any impurities that may be present. Methotrexate-1-monomethyl ester is also used as a pharmacopoeia standard for methotrexate and its metabolites.Formule :C21H24N8O5Degré de pureté :Min. 95%Masse moléculaire :468.47 g/molIvermectin Impurity K
CAS :Ivermectin Impurity K is an impurity in Ivermectin, a drug product. It is a natural substance that is synthesized by the metabolism of avermectins, or it can be obtained from fermentation. It has been shown to have anti-inflammatory properties in mice and rats. Ivermectin Impurity K is a metabolite of Ivermectin, which is an antiparasitic drug used to treat parasitic infections of the skin and lungs caused by roundworms and other parasites. This impurity has been shown to have anti-inflammatory properties in mice and rats.Formule :C48H76O14Degré de pureté :Min. 95%Masse moléculaire :877.11 g/molFR 901464
CAS :FR 901464 is a cytotoxic compound that inhibits the activity of the mammalian splicing factor receptor (SFRS2), which is involved in the splicing process. The active form of FR 901464 binds to SFRS2 and prevents it from binding to other proteins, thereby inhibiting the formation of functional complexes. This leads to an increase in the production of proteins that are not targeted for degradation and a decrease in the production of proteins targeted for degradation. This drug also has anti-inflammatory properties by inhibiting epidermal growth factor (EGF) and its receptor, EGF-R. It also has antimicrobial effects against some bacteria by inhibiting bacterial growth factors such as amide or conjugates.Formule :C27H41NO8Degré de pureté :Min. 95%Masse moléculaire :507.6 g/molPitavastatin N-oxide
CAS :Pitavastatin N-oxide is a drug product that is an analytical standard and natural API impurity. It is used in the synthesis of other drugs, such as pitavastatin, which is a statin drug used to lower cholesterol levels. Pitavastatin N-oxide has been shown to be a potent inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonate. This inhibits cholesterol production and lowers levels of low density lipoprotein (LDL) cholesterol in the blood.Formule :C25H24FNO5Degré de pureté :Min. 95%Masse moléculaire :437.46 g/molD-Pemetrexed Hydrate
CAS :Pemetrexed is an antifolate drug that is used to treat cancer. It is a prodrug of pemetrexed disodium, which is converted to pemetrexed in the body by esterases. Pemetrexed is metabolized to its active form, D-pemetrexed, which inhibits DNA synthesis and the growth of cells by inhibiting thymidylate synthase. D-Pemetrexed hydrate is a high purity, pharmacopoeia grade impurity standard for use in research and development or as a custom synthesis. It has been shown to inhibit the growth of certain types of cancer cells and can be used in combination with other treatments such as chemotherapy or radiation therapy.
Formule :C20H23N5O7Degré de pureté :Min. 95%Masse moléculaire :445.43 g/mol5,6-Dehydro-tigecycline
CAS :5,6-Dehydro-tigecycline is a synthetic antibiotic that is used for the treatment of multi-drug resistant bacterial infections. 5,6-Dehydro-tigecycline binds to the 30S ribosomal subunit and blocks protein synthesis by inhibiting peptidyl transferase activity. This drug has been shown to be effective in treating methicillin resistant Staphylococcus aureus (MRSA) infections. 5,6-Dehydro-tigecycline also inhibits the growth of Mycobacterium tuberculosis and Mycobacterium avium complex, although it is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Metabolism studies have shown that 5,6-Dehydro-tigecycline undergoes oxidative metabolism via CYP450 enzymes to form reactive metabolites like N2-[(
Formule :C29H37N5O8Degré de pureté :Min. 95%Masse moléculaire :583.63 g/mol(R,R)-Montelukast bis-sulfide
CAS :(R,R)-Montelukast bis-sulfide is a drug product that is used in the analytical and research and development of drugs. It is also used as an impurity standard for HPLC. (R,R)-Montelukast bis-sulfide has been shown to have niche applications in drug development and research, as well as being a high purity API.Formule :C41H46ClNO5S2Degré de pureté :90%MinMasse moléculaire :732.39 g/molClarithromycin EP Impurity A
CAS :Clarithromycin EP Impurity A is an analytical standard for clarithromycin. Clarithromycin EP Impurity A is a white to off-white powder that is soluble in methanol, acetone, and chloroform. It has a molecular weight of 459.23 Da and the chemical formula C18H26N2O5S. Clarithromycin EP Impurity A is an impurity found in clarithromycin that has been isolated from the product by high-performance liquid chromatography (HPLC) and confirmed by nuclear magnetic resonance spectroscopy (NMR). Clarithromycin EP Impurity A can be used as a reference standard for pharmacopoeia testing or as a research and development sample for drug development. It can also be synthesized from natural or synthetic sources.
Formule :C38H69NO14Degré de pureté :90%NmrCouleur et forme :PowderMasse moléculaire :763.95 g/molMelphalan dimer
CAS :Melphalan dimer is an anticancer drug that belongs to the class of kinase inhibitors. It works by inhibiting kinases, which are enzymes that play a critical role in cancer cell growth and survival. This medicinal compound has been shown to induce apoptosis or programmed cell death in human cancer cells. The analog of melphalan dimer has also been found in urine protein, indicating its potential as a biomarker for cancer diagnosis and treatment. Melphalan dimer is effective against various types of tumors, including Chinese hamster ovary cells and human melanoma cells. Its potent anticancer activity makes it a promising candidate for cancer therapy.Formule :C26H35Cl3N4O4Degré de pureté :Min. 95%Masse moléculaire :573.9 g/mol
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