Composés et métabolites pharmaceutiques et vétérinaires

<p>CAIR, an E. coli metabolite, helps identify its PurE active site and aids in fungal purine synthesis.</p>

<p>GyK, a bacterial sugar kinase, initiates glycerol metabolism by converting it into G3P, key for cell uptake.</p>

<p>Erucic acid sodium, a monounsaturated fatty acid (MUFA) extracted from the seeds of rapeseed, readily crosses the blood-brain barrier (BBB). It normalizes the accumulation of long-chain fatty acids in the brain, enhances cognitive function, and effectively prevents dementia.</p>

<p>Nuclease P1 cleaves single-stranded nucleic acids into 5'-mononucleotides; key in molecular biology, pharmaceuticals, and food.</p>

<p>NRT is an oral NAD+ precursor, boosts NAD+, activates SIRT1/3, provides vitamin B3, enhances metabolism, and may mitigate Alzheimer's.</p>

<p>13-cis-Retinyl acetate: active 13-cis isomer of Retinyl acetate, metabolite of vitamin A.</p>

<p>Saccharopine hydrochloride, from lysine degradation, disrupts mitochondria and hinders development.</p>

<p>PmST3 is a beta-galactoside enzyme adding sialic acid to glycoproteins and glycolipids.</p>

<p>N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription .</p>

<p>Orally active NAD+ booster, NR malate enhances metabolism, supports cognitive function, and is a vitamin B3 source.</p>

<p>Cholesteryl homo-γ-linolenate is a cholesterol ester.</p>

<p>21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is generated from 11-ketoprogesterone by the cytochrome P450 (CYP) isoform CYP17A1, and can also be produced by oxidation via 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) from 21-deoxycorticosterone. In patients with congenital adrenal hyperplasia, a metabolic disorder characterized by a deficiency of 21-hydroxylase, levels of 21-Deoxy Cortisone are elevated.</p>

<p>Uricase catalyzes uric acid to allantoin in many mammals' peroxisomes, used in biochemistry.</p>

<p>N-Lactylvaline is an endogenous metabolite detectable in patients with intermediate maple syrup urine disease.</p>

<p>AtGlcAK: GHMP-kinase family, specific for D-glucuronic acid, Km 0.7 mM, converts it with ATP to D-glucuronic-1-phosphate and ADP.</p>

<p>ACK, found in bacteria/archaea, phosphorylates acetate with ATP and cations, yielding acetyl-CoA; used in biochemistry.</p>

<p>N1-Acetylspermine, an endogenous metabolite found in urine, has applications in leukemia research [1] [2].</p>

<p>Estriol-3-glucuronide, a natural compound found in urine, is also present in amniotic fluid during normal pregnancy [1][2].</p>

<p>13-cis-Retinyl palmitate in corn flakes is 75% as active as all-trans form.</p>

<p>Neo-Inositol, a stable, polar compound, is a rare natural inositol stereoisomer.</p>