Acides aminés (AA)

<p>Gly-Asp-OH is a medicine that has proliferative activity. It is also an immunoregulatory and biologically active substance, which suppresses the production of cytokines IL-10 in mononuclear cells. Gly-Asp-OH is a synthetic compound with medicinal properties. The structure of this compound was elucidated by chemical analysis and spectroscopic methods. It can be used as an anti-inflammatory agent or to prevent cell death induced by necrosis or apoptosis.</p>

<p>DL-Proline is a biological molecule that has been shown to bind to the DNA binding domains of proteins. This binding can be seen with the crystal structures of DL-proline and protein. The reaction mechanism for DL-proline is as follows:<br><br>DL-Proline + Protein → Proline + Protein<br><br>The equilibrium constant for this reaction is 1.0 at 298 K. The pKa value for the amide group in DL-proline is 4.8, which means that it will react with water and form an amine group at physiological pH levels. DL-Proline has been shown to have metabolic disorders.</p>

<p>Antimicrobial cationic peptide; used for microscopy glass slides coating</p>

<p>1-(3,4-Methylenedioxyphenyl) 2-nitropropene (1-MPNP) is a phosphatase inhibitor that is active against gram-negative bacteria by inhibiting enterotoxins and chlamydia. 1-MPNP inhibits the activity of tyrosine phosphatases, which are enzymes that play a major role in bacterial virulence. 1-MPNP competitively inhibits the activity of tyrosine phosphatases and prevents them from catalyzing the hydrolysis of polyphosphate substrates. This inhibition leads to an accumulation of polyphosphates in the bacterial cell membrane, which disrupts its permeability and leads to cell death.</p>

<p>3,4-Methylenedioxy propiophenone is a synthetic compound with a fatty acid chain. It has been shown to have potent activity against leishmania and has been used as an intermediate in the synthesis of other drugs. 3,4-Methylenedioxy propiophenone can be synthesized by acylation reactions with chloride and acetylcholinesterase inhibition. This product also has molecular docking properties, which have been analyzed using computational methods, such as profiling and profile analysis.</p>

<p>Applications (Z)-Ethyl 2-((2S,4R,5S)-4,5-Dihydroxy-2-methoxydihydro-2H-pyran-3(4H)-ylidene)acetate-13C3 is a by-product intermediate in synthesizing Patulin-13C3 (P206502), a labelled Patulin (PAT). It is a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys, is mainly found in ripe apple and apple products. Patulin-induced genotoxicity and modulation of glutathione in Hep G2 cells. Antibiotic.<br>References Scott, P., et al.: J. Agric. Food Chem., 20, 450 (1972); Aden, D., et al.: Nature, 282, 615 (1979); Surralles, J., et al.: Mutat. Res., 341, 169 (1995); Alves, I., et al.: Mutagenesis, 15, 229 (2000); Liu, B., et al.: Toxicol. Appl. Pharmacol., 191, 255 (2003)<br></p>

<p>Applications 3-Acetylthio-2-methylpropanoic Acid-d5 (cas# 1189969-31-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-Hydroxy-7-methoxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one-d3 is an intermediate for the synthesis of Alternariol Monomethyl Ether-d3 (A575771), labelled methyl este analog fo Alternariol. An alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing the rate of DNA strand breaks.<br>References Asam, S., et al.: J. Agric. Food Chem., 57, 5152 (2009); Fehr, M., et al.: Mol. Nut. Food Res., 53, 441 (2009); Tiemann, U., et al.: Toxicol. Lett., 186, 139 (2009)<br></p>

<p>4-Chloro-2-methylbenzoic acid is a high quality chemical that is used as an intermediate in the preparation of other compounds. It belongs to the group of complex compounds and has CAS No. 7499-07-2. This reagent can be used to synthesize speciality chemicals, research chemicals, and versatile building blocks. 4-Chloro-2-methylbenzoic acid is also useful as a reaction component for the synthesis of fine chemicals, pharmaceuticals, and agrochemicals.</p>

<p>Please enquire for more information about 2-Chloro-N-cyclohexyl-N-phenylpropanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Applications 3-((2-Chlorothiazol-5-yl)methyl)-5-methyl-1,3,5-oxadiazinan-4-imine Hydrochloride is an intermediate for the synthesis of N-(3-((2-Chlorothiazol-5-yl)methyl)-5-methyl-1,3,5-oxadiazinan-4-ylidene)benzenesulfonamide (C385860), which is an impurity of Thiamethoxam (T344180), a neonicotinoid insecticide.<br>References Oliver, J., et al.: J. Environ. Horticult., 28, 135 (2010), Ghosh, A., et al.: J. Entomol. Res., 34, 35 (2010), Chem. and Eng. News 90: 10 (2012)<br></p>

<p>Applications N,N-[Iminobis(trimethylene)]bis-D-gluconamide (cas# 86303-20-0) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Methyl-d3-N-nitroso-p-toluenesulfonamide is the labeled version of Diazald; Diazomethane precursor.<br>References Takizawa, et al.: J. Pharm. Soc. Jpn., 70, 490 (1950)<br></p>

<p>Applications 2-(1-Cyano-1-methylethyl)azocarboxamide, cna be used in the synthesis of azobenzene side chain polymers derived from the bifunctional fumaric acid and itaconic acid.<br>References Kim, s. et al.: Polymer, Vol 55. P: 871-877 (2014);<br></p>

<p>1,1-Dichloro-1-fluoro-methanesulfenylchloride is a hazardous chemical that belongs to the group of chlorine compounds. It has been used as an antibacterial agent in the past and has been shown to be effective against nematodes, helminths, and some microorganisms. It is also used as a solvent in the production of dyes and perfumes. 1,1-Dichloro-1-fluoro-methanesulfenylchloride is not active against bacteria that are resistant to sulfonic acids or amines.</p>

<p>Diethoxy-methyl-thioxo-phosphorane is a chemical compound that is used in the manufacture of industrial chemicals. It has a vapor pressure of 0.0014 mmHg at 25°C, and can be quantified by chemical ionization with gas chromatography/mass spectrometry. Diethoxy-methyl-thioxo-phosphorane reacts with radiation to produce reactive oxygen species and other free radicals, which can damage DNA and cause cancer. The reaction rate is rapid, with an analogy to humans being exposed to nitrate compounds. Diethoxy-methyl-thioxo-phosphorane is also used in devices such as radiators and heaters, where it causes damage when combined with nitrates.</p>

<p>4-Methylpentanoic acid is a fatty acid that is the product of anaerobic fermentation in the colon and can be found as an end product in the body. It can be used as a substrate in film tests for detecting bacteria, such as Escherichia coli, which are associated with bowel diseases. 4-Methylpentanoic acid has been shown to have inhibitory effects against nuclear dna replication, mitochondrial membrane potential, and energy metabolism. 4-Methylpentanoic acid also has antiinflammatory properties and has been shown to decrease body mass index. The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is an antituberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription</p>

<p>Please enquire for more information about L-(-)-Glyceraldehyde - Technical grade aqueous solution including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Chloro-2-(methyl-phenyl-sulfamoyl)-benzoic acid methylester is an industrial chemical that is used in the production of other chemicals. It can be produced by the esterification of 4-chlorophenylacetic acid with methyl phenyl sulfonyl chloride, followed by diazotization and chlorination. This chemical also has the ability to form a condensation product with hydrazine.</p>

<p>Z-Ala-Arg-OH is a low molecular weight carboxylate that has an acidic, hydrophobic side chain. The chemical formula for Z-Ala-Arg-OH is C11H18N4O6. The chemical structure of Z-Ala-Arg-OH can be found in the figure below:<br>Z-Ala-Arg-OH is an ionizable, acidic compound with a pKa of 3.5. The functional groups on Z-Ala-Arg-OH are shown in the figure below:<br>The carboxylate group and the amine group are present in this molecule.<br>Z-Ala-Arg-OH is a transpeptidase, which catalyses the posttranslational modification of proteins by transferring amino acids from one protein to another during translation or after translation. Transpeptidases are important enzymes in bacterial cell wall synthesis because they catalyze peptide bond formation between two amino acid</p>

<p>C3d Peptide P16 H-Lys-Asn-Arg-Trp-Glu-Asp-Pro-Gly-Lys-Gln-Leu-Tyr-Asn-Val-Glu-Ala is a molecule that can be used as a diagnostic tool for cancer and other diseases. It is a hydroxylated analog of the amino acid Lysine, and has been shown to bind to tumor vasculature. C3d Peptide P16 H Lys Asn Arg Trp Glu Asp Pro Gly Lys Gln Leu Tyr Asn Val Glu Ala OH is a β amino acid with a carboxy terminal hydroxyl group. The reactive hydroxyl group reacts with other molecules in order to form conjugates, which are then attached to polymer surfaces for diagnostic purposes. C3d Peptide P16 H Lys Asn Arg Trp Glu Asp Pro Gly Lys Gl</p>

<p>Please enquire for more information about Ovalbumin (257-264) (chicken) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-phenylalanine is an amino acid that has a sweet taste. It is one of the 20 amino acids encoded by the universal genetic code, and is classified as a polar amino acid because it has a hydroxyl group on its side chain. L-Phenylalanine is used in the food industry as a sweetener and to enhance salty or acidic flavors. Phenylalanine has been shown to be an important precursor for several important neurotransmitters in the brain. This includes serotonin, dopamine, and norepinephrine. Phenylalanine also plays a role in protein metabolism and enzyme activity, including aminopeptidases and racemases, which are enzymes that catalyze reactions involving racemic mixtures.</p>

<p>Boc-Ala-Ala-Pro-Ala-pNA is a synthetic peptide analog of the amino acid sequence Pro-Gly-Arg. It has been shown to inhibit the proliferation of prostate cancer cells, as well as to inhibit tumor growth in animals. This peptide also inhibits protease activity in subtilisin and has been used to study the inhibition of angiogenesis by endothelial cell proliferation. The peptide is an inhibitor of ion exchange and has been used to study the effects of fatty acids on carcinoma cell lines. Boc-Ala-Ala-Pro-Ala-pNA has also been shown to be active against other animal cells and could be used for research purposes.</p>

<p>Please enquire for more information about 3-Iodo-L-tyrosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Gly-Trp-Gly-Gly-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Peptide YY (3-36) (human) trifluoroacetate salt H-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn -Arg -Tyr -Tyr -Ala -Ser -Leu -Arg <br>Peptide YY (3.36) is a peptide hormone that is secreted by L cells in the small intestine and colon. It has been shown to be an effective treatment for obesity, type 2 diabetes, and other metabolic disorders. Peptide YY (3.36) has been shown to increase insulin sensitivity, reduce food intake and body weight, increase metabolic rate, and improve glucose homeostasis in animal studies. In humans, it has been found to have similar effects on postprandial plasma levels of peptide YY (3.</p>

<p>Please enquire for more information about (Ala31, Aib 32)-Neuropeptide Y (porcine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-His-Arg-OH is a synthetic peptide that has been shown to have cytotoxic effects on mammalian cells. The H-His-Arg-OH peptide can be used for the treatment of heart disease and autoimmune diseases, such as rheumatoid arthritis. This peptide has been found to be resistant to congestive heart failure, which is caused by a number of factors, including hypertension and valvular stenosis. It has also been shown to have an immunoglobulin G1 (IgG1) genotype.</p>

<p>Please enquire for more information about (H-Arg-Gly-Phe-Ala-Phe-Val-Thr-Phe)8-MAP including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Z-Pro-Ala-OH is a carboxypeptidase enzyme that catalyzes the hydrolysis of the amide bond between the carboxyl group of glutamic acid and the amino group of proline. This enzyme can be found in wheat (Triticum aestivum), where it is present at high concentrations, and has a specificity for Z-Pro-Ala. The enzyme is active in muscle tissue, as well as in brain and cardiovascular tissues. It has been shown to have beneficial effects on cerebral cortex function and cardiovascular diseases. The enzyme is also specific to erythrocytes and plasma samples, with high activity levels observed in homogenates of both tissues.</p>