Acides aminés (AA)

Applications A metabolite common to all triazole fungicides: free triazole, 1,2,4-triazole (T), and its 2 conjugates: triazolylalanine (TA) and triazolylacetic acid (TAA).
References Hrudey, S., et al.: Water Sci. Technol., 20, 55 (1988), Froese, K., et al.: Water Res., 33, 1355 (1999), Hengel, M., et al.: J. Agric. Food Chem., 50, 3412 (2002),

Applications 2-Methylalanine is an Alanine (A481400) derivative. Alanine is an amino acid that occurs naturally in nature. It is a functional component in the alanine cycle which regulates the level of alanine aminotransferases which can be used as a diagnostic tool to predict type II diabetes.
References Naveed S. et al.: Diab., 53, 11 (2004); Barlind, J. et al.: Bioorg. Med. Chem. Lett., 23, 2721 (2013);

Applications N-Acetyl-DL-aspartic acid (cas# 2545-40-6) is a useful research chemical.

Applications 3-(2-Methoxy-5-methylphenyl)-3-phenyl-propanoic Acid (cas# 109089-77-2) is a compound useful in organic synthesis.

Impurity Ciclopirox EP Impurity B/ USP Ciclopirox Related Compound B
Applications 6-Cyclohexyl-4-methyl-2H-pyran-2-one (Ciclopirox EP Impurity B) is a a dialkylated pyranone derivative.

Applications 2-Amino-5-methylpyridine (cas# 1603-41-4) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Francotte, P., et al.: Bioorg. Med. Chem., 16, 9948 (2008), Sundaraganesan, N., et al.: J. Mol. Struc., 891, 284 (2008), Caleta, I., et al.: J. Med. Chem., 52, 1744 (2009),

Applications Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid is a reactant used in the preparation of peptidase IV inhibitors.
References Park, W. et al.: Bioorg. Med. Chem. Lett., 21, 1366 (2011);

Applications A reagent for high performance polymer research.
References Fouassier, J., et al.: Polymer, 36, 5005 (1995),

Applications 2-Furoylglycine is an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolylazabicyclooctylethylpiperidines as Ccr5 antagonists for the treatment of HIV infection.
References Antonysamy, S., et al.: Bioorg. Med. Chem. Lett., 18, 2990 (2008); Kazmierski, W., et al.: PCT Int. Appl. (2004), WO 2004054974 A2 20040701

Applications Fructose-histidine is an amadori compound formed in food.
References Wang, J., et al.: J. Mass Spec., 43, 262 (2008); Hashiba, H.: J. Agri. Food Chem., 24, 70 (1976)

Applications N-Methyl-p-tyramineúHCl (cas# 370-98-9) is a useful research chemical.

Stability Volatile
Applications 3-ETHYL-3-METHYLHEPTANE (cas# 17302-01-1) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
References Zhang, J. S., et al.: Org. Biomolec. Chem., 2015;

Applications 1-Methyl-4-nitropyrrole-2-carboxylic Acid is used in the synthesis of Lexitropsin and distamycin analogs with antimicrobial activities.
References Anthony, N., et al.: J. Med. Chem., 50, 6116 (2007); Khalaf, A., et al.: J. Med. Chem., 47, 2133 (2004)

Applications Intermediate for the preparation of Naratriptan and other indole sulfonamide derivatives.

Applications Dl-valine

M03001 - H-Gly-OH

Applications An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),

Stability Light Sensitive
Applications 4-Methoxyphenylhydrazine hydrochloride was used in the preparation of 5-cyano-3-(5-methoxy-2-methylindol-3-yl)-1,2,4-thiadiazole. It was also used to synthesize diarylpyrazoles as possible cyclooxygenase 2 ((COX-2)) inhibitors.
References Iwakawa, T., et al.: Chem. Pharm. Bull., 48, 160 (2000); Penning, T., et al.: J. Med. Chem., 40, 1347 (1997)

Applications L-Argininic Acid is a guanidino compound, of which accumulation in tissue can cause Hyperargininemia.
References Deignan, J., et al.: Mol. Gen. Metab., 93, 172 (2008); Balz, D., et al.: Intl. J. Develop. Neurosci., 21, 75 (2003); Wyse, A., et al.: Brain Res., 923, 50 (2001)

Applications N,N'-Di-4-pyridinyl-methanediamine is used to prepare bis(heteroaryl)-imidazolidinediones with oxalyl chloride.
References Ghandi, M., et al.: Synth. Comm., 37, 637 (2007)

Applications 3-Methyl-2-furoic Acid-d is a deuterated version of 3-Methyl-2-furoic Acid (M219553), a useful reactant in the synthesis of therapeutic agents.
References Dragovich, Peter S., et al.: Bioorg. & Med. Chem. Let., 24(3), 954-962 (2014);Garcia-Barrantes, Pedro M., et al.: J. of Med. Chem., 58(20), 7959-7971 (2015)

Stability Hygroscopic
Applications 3-Methylglutaconic acid is a glutarate which builds up in the urine in 3-methylglutaconic aciduria. 3-methylglutaconic aciduria is a term used to describe five different disorders that impair the functioning of energy-producing centers within cells (mitochondria)
References Walsh, R., et al.: J. Inherit. Metab. Dis., 22, 251 (1999); Gonzalez, I., et al.: Am J Med Genet A., 134, 409 (2005); MacKenzie, J., et al.: Biochim Biophys Acta., 1772, 509 (2007)

Applications 5-Methoxyindole-3-acetic Acid is a chemical reagent used in the analysis of the physiological properties of auxins.
References Ferro, N. et al.: J. Clin.Info. Model., 46, 1751 (2006);

Applications 3-Methylnonane-2,4-dione is a compound that possesses a butter-like and beany off flavour that is a result of flavour reversion of soya-bean oil. 3-Methylnonane-2,4-dione is also present in Japanese green tea and pressure-cooked hen meat.
References Farkaš, P., et al.: Food Chem., 60, 617 (1997); Guth, H. & Grosch, W.: Flav. Chem., No vol. given, 377 (1999); Kumazawa, K. & Masuda, H.: J. Agr. Food Chem., 47, 5169 (1999)

Applications 3-Methoxycatechol is used to prepare polyphenolic deoxybenzoins as potential antioxidants and tyrosinase inhibitors.
References Ng, L., et al.: Bioorg. Med. Chem., 17, 4360 (2009)

Applications β-Hydroxyisobutanol is used as a reagent in the synthesis of pyrazolo[1,5-a]pyridinecarbonyl-substituted spirocyclic piperidine ketals as inhibitors of HCV protein NS4B and of hepatitis C viral replication and their lack of cytotoxicity in human cells.
References Tai, V.W.-F., et al.: Bioorg. Med. Chem. Lett., 24, 2288 (2014);

Applications 4-Chloro-3-methylaniline (cas# 7149-75-9) is a compound useful in organic synthesis.

Applications 6-Methylpurine (cas# 2004-03-7) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 3-Methylindole metabolite.
References Skordos, K., et al.: Chem. Res. Toxicol., 11, 741 (1998), Lanza, D., et al.: Drug Metab. Disposition, 29, 950 (2001), Hoenicke, K., et al.: J. Agric. Food Chem., 50, 4303 (2002),

Applications 1,3,5-Trichloro-2-methylbenzene can be used as reactant/reagent in hydrodechlorination process and catalysts for the production of 2,​6-​dichlorotoluene from polychlorotoluene-​containing mixtures. Also, it is derived from 2,4,6-Trichlorobenzoic Acid (T774715), which is a possible degradation intermediate of Polychlorinated Biphenyls (PCBs) in contaminated soil, suggesting the occurrence of microbial transformation processes over time.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Eichinger, W., et al.: PCT Int. Appl., WO 2001017932 A1 20010315 (2001); Stella, T., et al.: Sci Total Environ, 533, 177-186 (2015)

Stability Moisture Sensitive
Applications A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2.
References Inoue, T., et al.: J. Biol. Chem., 284, 9566 (2009), Kang, J., et al.: Bioorg. Med. Chem., 17, 1498 (2009), Rath, G., et al.: Int. J. Biochem. Cell Biol., 41, 1165 (2009),

Impurity Imatinib EP Impurity G
Applications 1-Methylpiperazine (Imatinib EP Impurity G) is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP), an antimicrotubular drug. It is a COVID19-related research product.
References Mallevais, M.L. et al.: Biochimie, 66, 477 (1984);

Applications N-(2-Methyl-1-phenylpropan-2-yl)acetamide is a byproduct from the preparation of benzolactams by palladium-catalyzed carbonylation of arylethylamines and α-amino benzenepropanoates.
References Lopez, B., et al.: Chem. Commun., 47, 1054 (2011); Albert, J., et al.: Organometallics, 32, 649 (2013);

Applications Glycyl-D-phenylalanine (cas# 34258-14-5) is a useful research chemical.

Applications 3-Methyl-d3-4-nitrophenol-2,5,6-d3 (CAS# 1219803-89-0) is a useful isotopically labeled research compound.

Applications 4′-Methylpropiophenone is a chemical reagent used in electrocarboxylation reactions.
References Zhang, K. et al.: Chin. J. Chem., 28, 509 (2010); Zhao, S. et al.: Tetra. Lett., 52, 2702 (2011);

Applications A receptor adenine derivative binding membrane brain animal cell line.
References Camaioni, E., et al.: Bioorg. Med. Chem., 6, 523 (1998), Kelly, M., et al.: Br. J. Pharmacol., 125, 979 (1998), Redzic, Z., et al.: Brain Res., 888, 66 (2001), Levy, D., et al.: J. Med. Chem., 46, 2177 (2003),

Applications Ethyl [2-Methyl-3-(chlorosulfonyl)phenoxy]acetate (cas# 91427-62-2) is a compound useful in organic synthesis.

Applications An antibody agent.
References Rowell, F. J., et al.: Immunochemistry, 13, 891 (1976),

Applications N-Methylformanilide is an aromatic reagent used in the synthesis of dye-sensitized solar cells. Also used in the synthesis of potent tyrosinase inhibitors.
References Meyer, T et al.: J. Org. Chem., 77, 3704 (2012); Nihei, K. et al.: Bioorg. Med. Chem. Lett., 14, 681 (2004);

Applications N-Fmoc-L-tyrosine Benzyl Ester is used to synthesize truncated analogues of preptin-(1-16) as possible osteoblast proliferation stimulant. It is also an intermediate used to prepare phosphotyrosinyl phosphoramidite derivatives useful in the incorporation of multiple reporter groups on synthetic oligonucleotides.
References Kowalczyk, R., et al.: Bioorg. Med. Chem., 22, 3565 (2014); Misiura, K., et al.: Nucl. Acids Res., 18, 4345 (1990)

Stability Moisture Sensitive
Applications 4-chloro-5-fluoro-2-methoxypyrimidine (cas# 1801-06-5) is a useful research chemical.

Applications An inhibitor of the enzyme Glyoxalase 1.
References Vince, R. and Wadd, W.B.: Biochemical and Biophysical Res. Commun., 35, 5 (1969), Vegvari, A., et al.: ChemBioChem, 3(11), 1117 (2002)

Stability Hygroscopic
Applications 5-Methyl-2-furanmethanol (cas# 3857-25-8) is a compound useful in organic synthesis.

Applications 2-METHOXY-4-METHYLANILINE (cas# 39538-68-6) is a useful research chemical.

Applications Protected 1,2-Phenyldiamine, an intermediate in the synthesis of histone deacetylase agents and antitumor agents.
References Andrews, D., et al.: Bioorg. Med. Chem. Lett., 18, 2580 (2008), Mahboobi, S., et al.: J. Med. Chem., 52, 2265 (2009),

Applications 3-Formyl-5-methylbenzoic Acid

Applications 2,6-Di-(tert-butyl-d9)-4-methylphenol-3,5-d2,OD (CAS# 64502-99-4) is a useful isotopically labeled research compound.

Applications Metabolite of Theophylline and Caffeine.
References Yu, Ch. et al.: J. Bacteriol. 191, 4624 (2009); Geraets, L. et al.: Biochem. Pharmacol. 72, 902 (2006).

Applications 3-(4-Methylphenyl)-3-(trifluoromethyl)diaziridine (cas# 87736-82-1) is a compound useful in organic synthesis.

Applications 4-methoxy-3-methylaniline (cas# 136-90-3) is a useful research chemical.

Applications 2-Amino-6-methylpyrimidin-4(3H)-one (cas# 3977-29-5) is a useful research chemical.

Applications Substrate for TenA enzyme in the thiamin salvage pathway
References Jenkins, A., et al.: Nat. Chem. Biol., 3, 492 (2007), Jenkins, A., et al.: Bioorg. Chem., 36, 29 (2008),

Applications 5-Methyl-2-hexanone is used in the preparation od S1P1 receptor agonists. Also used in the preparation of indoles in an efficient synthesis involving the use of TCT (2,4,6-trichloro-1,3,5-triazine).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bolli, M. et al.: J. Med. Chem., 57, 78 (2014); Siddalingamurthy, E. et al.: Tetrahedron Lett., 54, 5591 (2013);

Applications 2,6-Di-tert-butyl-4-methyl-d3-phenol (CAS# 86819-59-2) is a useful isotopically labeled research compound. This compound has been shown to significantly have lower toxic potency in mice compared to butylated hydroxytolune (BHT).
References Mizutani, T., et.al., Toxicol. Appl. Pharmacol. 69,283-290,(1983);

Stability Hygroscopic
Applications 1-(2-Methoxyphenyl)piperazine Hydrobromide is a useful reagent for improving the synthesis of Eapidil.
References Wang, H., et al.: Anhui Huagong, 37, 23 (2011)

Stability Temperature Sensitive
Applications Precursor of Diazomethane. It has a cytotoxicity effect.This product contains an undetermined amount of water.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Huggins, C., et al.: J. Exp. Med., 131, 321 (1970), Gullino, P.M., et al.: J. Natl. Cancer Inst., 54, 401 (1975),

Applications It is a versatile industrial solvent. NMP is currently approved for use only in veterinary pharmaceuticals. The determination of the disposition and metabolism of NMP in the rat will contribute toward understanding the toxicology of this exogenous chemical which man may likely be exposed to in increasing amounts.
References Southwell, D., et al.: J. Pharm. Pharmacol., 33, 3 (1981), Barry, W., et al.: J. Invest. Dermatol., 82, 49 (1984),

Applications 4-Bromo-3-methylpyridine, HCl

Applications Phytosiderophores are produced in higher plants as iron chelating amino acids that promote uptake of iron from soil.
References Klair, S., et al.: J. Plant Nutr., 19, 1295 (1996),