Acides aminés (AA)

Applications Intermediate in transsulfuration whereby the mammal transfers the sulfur of methionine via homocysteine to cysteine.
References Prochazka, Z., et al.: Collection Czechoslov. Chem. Commun., 45, 1982 (1980), Yorek, M.A. & Spector, A.A.: Prog. Clin. Biol. Res., 179, 361 (1985)

Impurity Azathioprine EP Impurity C
Applications 5-Chloro-1-methyl-4-nitroimidazole (cas# 4897-25-0) is a compound useful in organic synthesis.

Applications L-Cystine Bis(T-butyl Ester) Dihydrochloride is used as a reagent in the synthesis of chelate oxorhenium to create new integrin antagonists.
References Le Gal, J., et al.: J. Inorg. Biochem., 105, 880 (2011);

Applications 2-Amino-6-methylpyrimidin-4(3H)-one (cas# 3977-29-5) is a useful research chemical.

Stability Moisture Sensitive
Applications 4-chloro-5-fluoro-2-methoxypyrimidine (cas# 1801-06-5) is a useful research chemical.

Applications N-[(R)-1-Carbethoxybutyl]-(S)-alanine is an intermediate in the synthesis of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.
References Pascard, C., et al.: J. Med. Chem., 34, 663 (1991)

Impurity Cefoperazone EP Impurity C
Applications N-Methyl-5-tetrazolethiol (Cefoperazone EP Impurity C) is an impurity of Cefoperazone.
References Kitson, T., et al.: Biochem. J., 175, 83 (1978), Elenbaas, R., et al.: Clin. Pharmacol. Ther., 32, 347(1982),

Applications N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine (cas# 101988-70-9) is a useful research chemical.

Applications 2-Methyl-7-methylamino-8-nitro-quinoxaline (cas# 78411-55-9) is a compound useful in organic synthesis.

Applications N-Methyl-N-nitroso Urea-d6 is the labelled form of N-Methyl-N-nitroso Urea (M325815), which is a precursor of Diazomethane. It has a cytotoxicity effect.
References Huggins, C., et al.: J. Exp. Med., 131, 321 (1970); Gullino, P.M., et al.: J. Natl. Cancer Inst., 54, 401 (1975)

Applications 2-Methoxy-1-[4-(oxiranylmethoxy)phenyl]ethanone (cas# 110458-44-1) is a compound useful in organic synthesis.

Applications L-Serine is used in the synthesis of purines and pyrimidines as antibacterial/antifungal agents, as well as acting as a proteinogenic compound.
References Olivella, M. et al.: Bioorg. Med. Chem., 20, 6109 (2012);

Applications N-Acetyl-S-phenyl-d5-DL-cysteine is the deuterium labelled form of N-Acetyl-S-phenyl-DL-cysteine, which is used as a reactant in the preparation of potent HIV-1 protease inhibitors that use D-amino acids as P2/P3 ligands.
References Jungheim, L., et al.: J. Med. Chem., 39, 96 (1996);

Applications Tetrahydro-5-methyl-2-furanol is an intermediate in synthesizing 2,3-Dihydro-2-methylfuran (D447355), which is a general reagent used in next generation of biofuels. Dihydrofuranyl derivative.
References Simmie, J. et al.: J. Phys Chem., 116, 4528 (2012);

Applications N-Boc-piperazine (cas# 57260-71-6) is a compound useful in organic synthesis.

Applications This compound contains up to 25% of the two other regioisiomers.

Applications Guaiacol-beta-D-glucopyranoside, is a Guaiacol Conjugate, that has shown to present in fermentation of grapes that had been exposed to bushfire smoke and can potentially yield unpalatable, smoke-affected wine.
References Hayasaka, Y.m et al.: J. Arg. Food Chem., Vol. 58, Issue 4, P: 2076; 2081 (2010);

Applications 4-Methyl-6-(methylamino)-1,3,5-triazin-2(1H)-one is a heterocyclic Triazine based building block useful in organic synthesis. It is related to 2-Amino-4-methoxy-6-methyl-1,3,5-triazine (A616880), which is used to synthesize pesticides.
References Klein, J., et al.: J. AOAC Intrnational, 86, 1015 (2003); Pang, G., et al.: J. Chromat. A, 1125, 1 (2006);

Applications Used in the synthesis of DMPO-type spin traps.
References Konaka, R., et al.: Free Radical Res., 23, 15 (1995),

Applications 5-Methylcytosine (cas# 554-01-8) is a useful research chemical.

Applications A well-known, highly active stimulant of cell divisions in plant tissue cultures.
References D.S. Letham: Phytochemistry, 12, 2445 (1973)

Applications (1-Chlorocyclohexyl)cyclohexyl-methanone is a synthetic intermediate and a potential reagent for the synthesis of Dicyclomine Impurity A (B382435) and Dihexyverine Hydrochloride (D448200).
References Cramer, R., et al.: J. Med. Chem., 47, 6777 (2004); Vilar, S., et al.: J. Med. Chem., 49, 1118 (2006); Kopp, M., et al.: B. Soc. Chim. Fr., no vol., 84 (1952); Levy, J., et al.: CR. Soc. Biol., 144, 339 (1950)

Stability Hygroscopic
Applications L-Formiminoglutamic acid is a useful research chemical. It is used medically in the diagnosis of Cobalt deficiencies in Cattle and sheep.
References Marsh, K. B., et al.: New Zeal. J. Agric. Res., 31, 273 (1988); Quirk, M. F., et al.: J. Agric. Sci., 110, 465 (1988); Quirk, M. F., et al.: Aust. J. Agric. Res., 38, 1071 (1987)

Applications A product from thermal and hydrolytic degradation of Orlistat. Orlistat impurity.
References Stalder, H., et al.: Helv. Chimica Acta, 75, 1593 (1992),

Applications N-Succinimidyl 3-Methoxy-4-nitrobenzoate (cas# 2006277-78-5) is a useful research chemical.

Applications An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),

Stability Hygroscopic
Applications 4-Methyl-2-oxovaleric Acid is an α-ketomonocarboxylic acid that triggers insulin release by acting upon receptor sites which differ from those occupied by amino acids. 4-Methyl-2-oxovaleric Acid is an intermediate in the metabolism of Leucine.
References Panten, U. et al.: Naun.-Schmied. Arch. Pharmacol., 291, 405 (1975); Vague, P. et al.: Diab. Metab., 1, 185 (1975); Francois, G. et al.: Lancet, 1, 858 (1984);

Applications L-Allo-isoleucine-d10 is a derivative compound of L-allo-isoleucine (A548200), which has been suggested to induce epithelial β-defensin expression. In addition, L-allo-isoleucine is utilized in the biosynthesis pathway for coronamic acid.
References Fehlbaum, P., et al.: Proc. Natl. Acad. Sci. USA 97, 12723 (2000); Parry, R. J., et al.: J. Am. Chem. Soc. 113, 1849 (1991)

Applications 3-Acetyl-2-methylquinoxaline is an intermediate in the synthesis of Desoxyquinocetone which is a metabolite of the veterinay drug Quinocetone.
References Li, Y. et al.: J. AOAC Int., 91, 1494 (2008); Liu, Z.-Y. et al.: Anal. Bioanal. Chem., 396, 1259 (1271);

Applications 3-Hydroxy-4-methylaniline

Applications Isopropyl 2-bromo-2-methylpropanoate (cas# 51368-55-9) is a useful research chemical.

Stability Moisture Sensitive
Applications (Z)-Metominostrobin (cas# 133408-51-2) is a compound useful in organic synthesis.

Applications H-PRO-GLU-OH (cas# 67644-00-2) is a useful research chemical.

Applications 1,3,5-Trichloro-2-methylbenzene can be used as reactant/reagent in hydrodechlorination process and catalysts for the production of 2,​6-​dichlorotoluene from polychlorotoluene-​containing mixtures. Also, it is derived from 2,4,6-Trichlorobenzoic Acid (T774715), which is a possible degradation intermediate of Polychlorinated Biphenyls (PCBs) in contaminated soil, suggesting the occurrence of microbial transformation processes over time.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Eichinger, W., et al.: PCT Int. Appl., WO 2001017932 A1 20010315 (2001); Stella, T., et al.: Sci Total Environ, 533, 177-186 (2015)

Applications 8-Methoxycarbonyloctanoic Acid (cas# 2104-19-0) is a compound useful in organic synthesis.

Applications Protected 1,2-Phenyldiamine, an intermediate in the synthesis of histone deacetylase agents and antitumor agents.
References Andrews, D., et al.: Bioorg. Med. Chem. Lett., 18, 2580 (2008), Mahboobi, S., et al.: J. Med. Chem., 52, 2265 (2009),

Applications DL-2-aminobutyric acid

Stability Air Sensitive
Applications 4-Chloro-2-methylaniline
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-Methyl-d3-propyl-3,3,3-d3 Alcohol (CAS# 72182-69-5) is a useful isotopically labeled research compound.

Stability Hygroscopic
Applications 3-Methylglutaconic acid is a glutarate which builds up in the urine in 3-methylglutaconic aciduria. 3-methylglutaconic aciduria is a term used to describe five different disorders that impair the functioning of energy-producing centers within cells (mitochondria)
References Walsh, R., et al.: J. Inherit. Metab. Dis., 22, 251 (1999); Gonzalez, I., et al.: Am J Med Genet A., 134, 409 (2005); MacKenzie, J., et al.: Biochim Biophys Acta., 1772, 509 (2007)

Stability Light Sensitive, Volatile
Applications Labelled 2-Methylfuran (M305440). 2-Methylfuran is a volatile organic compound (VOCs) used as a potential non-intrusive tool for screening of lung cancer.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References McWilliams, et al.: Curr. Oncol. Rep., 4, 487 (2002), Buszewski, B., et al.: Biomed. Chromatogr., 21, 553 (2007), Ligor, T., et al.: J. Breath. Res., 1, 1 (2007),

Stability Air Sensitive
Applications N-Formyl Ephedrine (Mixture of Diastereomers) can be used as a potential radiation-protective agent.
References Bhat, K.V., et.al.:J. Pharm. Sci., 54, 225-28, (1965);

Applications 5-Methylfurfural is a common chemical reagent used in a wide variety of chemical reactions and organic synthesis. Polycyclic pyridazine based derivatives are synthesized with this compound to form antimicrobial agents. Also used in the preparation of antiinflammatory diarylpentanoid analogues.
References Deeb, A. et al.: Eur. Chem. Bull., 3, 897 (2014); Leong, S. et al.: Molecules, 19, 16058 (2014);

Stability Hygroscopic
Applications 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is used as a reagent in the synthesis of N-(2-acylaminobenzyl or 2-acylaminoheterocyclylmethyl)thiophene-2-carboxamide derivatives as antithrombotics. It is also used as a reagent in the synthesis of diamide derivatives as FXa inhibitors. 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is an intermediate for Edoxaban (E555520).
References Mochizuki, A., et al.: Jpn. Kokai Tokkyo Koho. JP 2010120852 A 20100603. Jun 3, 2010; Mochizuki, A., et al.: PCT Int. Appl. WO 2008123017 A1 20081016. Oct 16, 2008

Applications (3-Methyl-2-butenyl)triphenyl-phosphonium Bromide (cas# 1530-34-3 ) is a compound useful in organic synthesis.

Applications L-Glutamic acid 5-methyl ester is a protected form of L-Glutamic acid (G596960). L-Glutamic acid is a nonessential amino acid that is important to the mammalian central nervous system. L-Glutamic acid is also a neurotransmitter for cone photoreceptors in the human brain and is used as a treatment for patients who have liver disease accompanied by encephalopathy (a condition termed ‘hepatic coma’).
References Anderson, H., et al.: J. Nutr., 99, 82 (1969); Brandon, C. & Lam, D.: Proc. Nat. Acad. Sci., 80, 5117 (1983); McDermott Jr, W., et al.: New Engl. J. Med., 253, 1093 (1955)

Applications MNC is on the metabolic pathway for 2,4-Dinitotoluene degradation.
References Spangoord, R.J., et al.: App. and Environ. Microbiology, 57, 11, 3200 (1991)

Applications N-Methylacetamide can be used for the synthesis of N-​sulfonyl amidines and acyl sulfonyl ureas.Environmental contaminants; food contaminants.
References Chow, S. Y., et al.: J. Org. Chem. 82, 2515 (2017)

Applications Isotope labelled L-Serine is used in the synthesis of purines and pyrimidines as antibacterial/antifungal agents, as well as acting as a proteinogenic compound.
References Olivella, M. et al.: Bioorg. Med. Chem., 20, 6109 (2012);

Applications 4-[2-(4-Hydroxyphenyl)-4-methylpentan-2-yl]phenol could be a useful reagent for making visible-transparent aromatic polymers.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Agou, T., et al.: Macromolecules (Washington, DC, U. S.), 53, 2942 (2020)

Applications Labelled Tiopronin. It is used as antidote against heavy metal poisoning; hepatoprotectant; mucolytic.
References Capasso, F., et al.: Agents Actions, 11, 741 (1981), Amor, B., et al.: Arthritis Rheum., 25, 698 (1982), Ichida, F., et al.: J. Int. Med. Res., 10, 325 (1982),

Applications L-Glutamine (Alpha-15n, 98%) (cas# 80143-57-3) is a useful research chemical.

Applications 4,4'-Methylenebis[2-chlorophenol] is used in the manufacture of fire-resistant polyester material and is used in the synthesis of photo-sensitive print plates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yu, S. et al.: Faming Zhuanli Shenqing (2009), CN 101597219 A 20091209.

Applications L-Glutamic Acid-d5 is an non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. It is also a key molecule in cellular metabolism.
References McEntee, W., et al.: Psychopharmacology, 111, 391 (1993), Manev, H., et al.: Mol. Pharmacol., 36, 106 (1989)

Stability Very Hygroscopic
Applications 1-O-Dimethoxytrityl-2-(N-Fmoc)-4-Aminobutyl)-1,3-propanediol is a useful reagent for the synthesis of acridine and​/or lipid containing oligodeoxyribonucleotides.
References Marasco, C. J., et al.: Tetra. Lett., 35, 3029 (1994)

Applications A labelled metabolite of Toluene.
References Gargas, M., et al.: Toxicol. Appl. Pharmacol., 98, 87 (1989), Commandeur, J., et al.: Pharmacol. Rev., 47(2), 271 (1995), Campo, P., et al.: Neurotoxicol. Teratol., 21, 427 (1999), Lohse, C., et al.: J. Agr. Food Chem., 48, 5913 (2000),

Applications 2,2-Dimethoxy-N-methylethanamine is an impurity formed in the synthetic process of Methimazole (M260300), a thiourea antithyroid agent that prevents iodine organification,
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sitar, D.S., et al.: J. Pharmacol. Exp. Ther., 184, 432 (1973), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 8, 351 (1979), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984), Atterwill, C.K., et al.: Food Chem. Toxicol., 29, 355 (1991),

M03001 - H-Gly-OH