Acides aminés (AA)

<p>Z-Ala-Ile-OH is a hydroxamic acid that is used in peptide synthesis. It is a monomer that is hydrophobic and has an affinity for peptidyl acceptors. The synthetic method for Z-Ala-Ile-OH involves the use of aspartic acid and aspartate semialdehyde, which are used to synthesize the hydroxamic acid via an amidation reaction. The nomenclature of Z-Ala-Ile-OH is based on its structure and the order of amino acids found in it. Aspartic acid and asparagine are both amino acids found in Z-Ala-Ile-OH, with the -NH2 group being replaced by -OH in this particular molecule. This substitution results in a more hydrophobic compound than aspartate semialdehyde.</p>

<p>PACAP-38 (28-38) is a peptide hormone that is produced in the brain and regulates various physiological processes. It has been shown to have effects on intestinal, pancreatic, and lung cells. PACAP-38 (28-38) is a potent antagonist of vasoactive intestinal polypeptide (VIP), which has been implicated in the regulation of gastrointestinal motility and fluid secretion. The peptide also inhibits cancer cell proliferation by activating cell death pathways.</p>

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<p>Please enquire for more information about Brain-Binding Peptide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Key subunit of extracellular plaques found in the brains of patients with Alzheimer's disease; Hydrochloride salt</p>

<p>Fmoc-3-(4'-pyridyl)-L-alanine is a heterocyclic compound that is an intermediate in the synthesis of other pharmaceuticals. It can be obtained by the trituration of Fmoc-3-(4'-pyridyl)-L-alanine hydrochloride with ether, followed by transfer of the resulting solid to a reaction vessel. The product can then undergo further synthetic transformations such as functionalizations and yields. This chemical is used in organic chemistry as a heterocycle.</p>

<p>Please enquire for more information about (d(CH2)51,D-Ile2,Ile4,Arg8)-Vasopressin b-Mercapto-b,b-cyclopentamethylene-propionyl-D-Ile-Phe-Ile-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfid e bond) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Neuropeptide Y (18-36) trifluoroacetate salt H-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg -Gln is a peptide belonging to the family of neuropeptides. It has been shown to have potent vasoconstricting activity in rat and guinea pig hearts, as well as contractile activity in rat aortic rings. Neuropeptide Y (18 - 36) trifluoroacetate salt H -Ala -Arg Tyr Tyr Ser Ala Leu Arg His Tyr Ile Asn Leu Ile Thr Arg Gln Arg Tyr NH2 trifl uoroacetate salt also inhibits the cyclase activity of adenylate cyclase, which is responsible for generating the second messenger cAMP. This compound may be used to treat congest</p>

<p>Please enquire for more information about Fmoc-Lys(Dabsyl)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Gly-Ala-Hyp-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Methyl-1-cyclohexanecarboxylic acid is a fatty acid that is present in the conjugates of natural and synthetic oils. It is an unsaturated fatty acid with a cycloalkane ring structure. The synthesis of 1-methyl-1-cyclohexanecarboxylic acid has been shown to be catalyzed by a carboxylase, which converts acetyl CoA into malonyl CoA. This reaction is irreversible and can be used as the first step in the biosynthesis of fatty acids. 1-Methyl-1-cyclohexanecarboxylic acid has been shown to cause cell death in leukemia cells, as well as inhibit epileptic seizures in rats.</p>

<p>Phe-Leu-OH is an enzyme that has been found to be involved in the synthesis of meningococcal disease. In addition, it has been shown to have diagnostic potential for the detection of this disease. The enzyme is expressed on the surface of meningococci and produces a protein antigen which can be detected by the presence of antibodies in patient serum. Phe-Leu-OH is also involved in the synthesis of Phe-Leu amide, which may inhibit binding of inhibitor molecules to membrane channels. This activity may be related to its ability to cause a decrease in ion flow across cell membranes.</p>

<p>Please enquire for more information about Antho-RPamide III·HCl Pyr-Val-Lys-Leu-Tyr-Arg-Pro-NH2·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Please enquire for more information about Cys-Gly-Lys-Lys-Gly-Amyloid b-Protein (35-40) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Tyr0)-Stresscopin (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Glu(Gly-OH)-OH is a glutamic acid amide. It is used as a diagnostic reagent for the detection of spontaneous activity in cell cultures. H-Glu(Gly-OH)-OH is synthesized by reaction of glutamic acid with glycine and hydrochloric acid, followed by neutralization with sodium hydroxide. The compound can be analyzed using gel permeation chromatography and mass spectrometry methods. The stability of H-Glu(Gly-OH)-OH in solution has been validated by comparing it to other compounds that have similar properties, such as glutamate and glutamine. This compound has been found to be stable in urine samples at concentrations up to 10 mM for 24 hours at room temperature and pH 7.0.</p>

<p>Please enquire for more information about Acetyl-(Asn30,Tyr32)-Calcitonin (8-32) (salmon I) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PTH-Related Protein (1-34) is a potent antagonist of the PTH/PTHrP receptor, which belongs to the family of peptide hormones. It can be used for the treatment of osteoporosis and certain types of cancer. It inhibits bone resorption by binding to the receptor in bone cells and blocking PTH/PTHrP-induced activation of phosphaturic acid phosphatase. This drug also inhibits the production of insulin-like growth factor I (IGF-I) and its receptors, which may lead to an anti-cancer effect. PTH-Related Protein (1-34) has been shown to have a high specificity for the PTH/PTHrP receptor, with moderate affinity for other receptors such as glucagon and somatostatin. The peptide is amphipathic, meaning it has both hydrophilic and hydrophobic regions. This characteristic allows it to penetrate cell membranes more easily than other</p>

<p>Please enquire for more information about H-Gly-Arg-bNA hydrochloride salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-D-Met-Met-Met-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about pTH (1-38) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Z-Ala-Ser-OMe is a peptide that is produced by catalyzed amide bond formation between the carboxylic acid group of Z-Ala and the amino group of Ser. This peptide has been shown to have a molecular weight of 564.2 and a melting point of 139°C. The peptides are coupled by d-amino acid residues to form chains, which are then esterified with acyl groups to yield Z-Ala-Ser-OMe.</p>

<p>Please enquire for more information about Cortistatin-29 (rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Val-Val-Val-OH is an enantiomer of H-Val-Gly-Thr-Phe, a linear model of the apical region of the Caco2 cell. It is also a monolayer that has hydrogen bonds with other molecules. Molecular modeling shows that H-Val-Val-Val-OH inhibits the uptake of glucose by Caco2 cells. The transport properties of this molecule are not well understood, but it may inhibit glucose transport in the small intestine by binding to glucose transporter 2 (GLUT2). Chromatographic methods have been used to analyze H-Val-Val-Val-OH and its inhibition on growth factor activity.</p>

<p>This linker is chemically stable and not cleavable under standard intracellular or extracellular conditions. N-Boc-3-Azetidinol is also a versatile organic intermediate used primarily in the pharmaceutical industry for synthesizing a wide range of drugs, including antibacterials, immunosuppressants, and cancer therapies.</p>

<p>Please enquire for more information about H-Ala-Lys-Leu-Arg-Glu-Arg-Leu-Lys-Gln-Arg-Gln-Gln-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Ile-Leu-Phe-Leu-Gln-Glu-Gly-Gly-Leu-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Z-Ala-Asn-OH is a hydrophobic amino acid that is used in industrial applications, such as paints and coatings. It can be synthesized from L-alanine and D-asparagine by the enzyme carboxypeptidase Y. Z-Ala-Asn-OH has been shown to have relevance for biochemically screening hyperthermophilic microorganisms, such as E. coli or other bacteria from the family Enterobacteriaceae. This amino acid has also been shown to be an essential component of a consortium of gram negative bacteria that produce an enzyme called xylanase and are used in the production of xylitol.</p>

<p>Please enquire for more information about Galanin Message Associated Peptide (25-41) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Z-Lys(Boc)-Leu-OMe including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(Des-Leu9)-Kinetensin H-Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-OH is an analog of kinetensin, a peptide hormone that stimulates pancreatic exocrine secretions. (Des-Leu9)-Kinetensin H-Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe has been shown to have a specific interaction with the albumin protein, which is the major plasma protein in humans. This peptide can inhibit protein synthesis and may be used as a treatment for chronic renal failure, cystic fibrosis, malignant hypertension, and other conditions. The sequence of this peptide is homologous to the sequence of human kinetensin. Electron microscopic analysis showed that it has a hydrophobic side chain and an amphipathic structure.</p>

<p>Neurotensin is a peptide hormone that regulates the release of other hormones and neurotransmitters, such as dopamine. It has been shown to be able to regulate appetite and bowel disease in animal models. Neurotensin acetate salt Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH acetate salt is a neurotensin molecule with an acetate group attached to it. This molecule is completely soluble in water and has been shown to have no effect on energy metabolism or polymerase chain reactions.</p>

<p>Please enquire for more information about Galanin Message Associated Peptide (16-41) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about VEGFR-KDR/Flk-1 Antagonist Peptide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Ser-Leu-Leu-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Boc-Met-Enkephalin is a hexapeptide that is derived from the amino acid Met. It is related to the opioid peptide Met-enkephalin, which has been shown to be involved in pain modulation and emotional responses such as fear and pleasure. Boc-Met-Enkephalin was synthesized by coupling two different fragments through an amide bond. The sequential order of these fragments was determined by high-resolution NMR spectroscopy. The carbonyl groups on the peptides were identified by using heteronuclear 2D correlation experiments. This sequence of carbons was demonstrated with 13C and 15N spectroscopy, in which it was found that there are three molecules of methylene carbon per molecule of Boc-Met-Enkephalin.</p>

<p>H-His-His-OH trifluoroacetate salt is a compound that has been extensively studied for its potential use in antimicrobial peptides. It is a small molecule that inhibits the activity of enzymes by binding to a specific region on the enzyme's surface, thereby preventing the progression of an essential chemical reaction. H-His-His-OH trifluoroacetate salt has been shown to inhibit protein synthesis in bacteria and yeast cells, as well as in model systems. The inhibition of protein synthesis may be due to hydrogen bonding between the hydroxyl group on His and the amino groups on His. H-His-His-OH trifluoroacetate salt also has an inhibitory effect on enzymes catalysis and can enhance their activity when used with another substrate.</p>

<p>H-Glu-Glu-Glu-OH is an amino acid sequence that has been shown to have low toxicity and a high therapeutic index. It is a carboxyl group containing oligopeptide, which can be used as a treatment agent for various conditions. H-Glu-Glu-Glu-OH has an amino group and acidic side chain at the COOH terminus, which is responsible for its protonated form. This protonated form of H-Glu-Glu-Glu-OH binds to the follicle cells in the ovaries, inhibiting them from releasing eggs. The carboxyl terminus of H-Glu-Glu-Glgol OH is deprotonated, which allows it to bind to the cell membrane surface of cancer cells and inhibit their growth by interfering with protein synthesis.</p>

<p>Trifluoroacetate salt</p>

<p>Suc-Gly-Pro-pNA is a proteolytic enzyme that hydrolyzes proteins. It has been shown to have potential for use as an anti-inflammatory agent. Suc-Gly-Pro-pNA has high proteolytic activity and can cleave peptide hormones such as angiotensin II and vasopressin. It also has thermal stability, and can tolerate high concentrations of salt and heat, making it suitable for therapeutic purposes. Suc-Gly-Pro-pNA binds to peptides with carboxy terminal residues by substrate binding, which may be the reason for its high degree of specificity. This enzyme is expressed in the cytosol and extracellular environment.</p>

<p>Please enquire for more information about Somatostatin-14 (7-14) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Nle 35)-Amyloid b-Protein (1-42) ammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fmoc-Arg(Z)2-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ac-Val-Asp-Val-Ala-Asp-aldehyde is a pseudo acid that is used in molecular modeling and kinetic studies. Ac-Val-Asp-Val-Ala-Asp-aldehyde has been shown to be a potent inhibitor of caspase activity and has been shown to inhibit the activity of various other enzymes as well, including cyclohexane ring hydroxylases and nitroreductases. Ac-Val-Asp-Val-Ala-Asp--aldehyde analogs are being studied for their ability to bind to specific proteins or inhibit enzyme activities. Ac-- Val-- Asp-- Val-- Ala-- Asp-- aldehyde binds to the active site of caspase 3 and prevents it from cleaving its target protein, which leads to cell death.</p>

<p>Please enquire for more information about (Trp3,Arg5)-Ghrelin (1-5) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Polymyxin B is a polycationic antibiotic that has been used in the treatment of infectious diseases and as an ophthalmic ointment. It is effective against bacteria, fungi, and parasites. Polymyxin B exhibits antimicrobial activity by binding to microbial membranes and causing lysis. The redox potential of this antibiotic is low, which can make it difficult for it to penetrate into cells. Oral cephalosporins are acidic drugs that are poorly absorbed from the gastrointestinal tract; they are only active in the distal small intestine and colon. Streptococcus faecalis is a bacterium that causes infections in the upper respiratory tract and urinary tract. Polymyxin B may be used as an oral agent to treat these infections because it does not require acidity for activity. This drug also exhibits anti-inflammatory effects through its ability to inhibit gamma-aminobutyric acid (GABA) synthesis in bowel cells, which leads to decreased inflammation.</p>

<p>Please enquire for more information about Big Endothelin-1 (porcine) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fmoc-Gly-Wang resin (100-200 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Asp-Phe-NH2 is a carboxy terminal amide of angiotensin, which is a peptide hormone. It is an analog of angiotensin II, which has been shown to have a number of therapeutic effects in the treatment of infectious diseases and cancer. H-Asp-Phe-NH2 has been shown to activate the angiotensin system by binding to serine protease, thereby regulating blood pressure and body fluid levels. This drug also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. The optimal pH for this chemical reaction is 7.5. Structural studies on this compound have revealed that it can form hydrogen bonds with amino acids in proteins and tissues such as cysteine, histidine, and lysine.</p>

<p>Please enquire for more information about Fmoc-b-(2-thienyl)-L-alanine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Gly-Gly-Met-OH is a hydrophobic amino acid with a decelerated reaction. It has been shown to modulate the growth of organisms, such as Staphylococcus aureus and Streptococcus pneumoniae. This molecule also has aspirin-like activity against S. aureus and can be used for cavity prevention. H-Gly-Gly-Met-OH is effective in inhibiting the growth of S. aureus, but not against Streptococcus pneumoniae. The test organism used in this study was Escherichia coli K12. H-Gly-Gly-Met-OH has been shown to have sequences that are similar to those found in kinetically slow peptides and tripeptides, which may explain its stability when encapsulated in liposomes for oral administration.</p>

<p>S-(1,2-Dicarboxyethyl)glutathione is a glutathione analogue that has been shown to prevent acetaminophen-induced hepatotoxicity in mice. It inhibits the reaction between acetaminophen and hepatic microsomal cytochrome P450 enzymes, which prevents the formation of toxic metabolites. S-(1,2-Dicarboxyethyl)glutathione also inhibits the production of serotonin by inhibiting the enzyme tryptophan hydroxylase. This drug has an anticoagulant effect by preventing the conversion of prothrombin to thrombin. S-(1,2-Dicarboxyethyl)glutathione also affects growth factors and collagen synthesis by affecting both epidermal growth factor (EGF) and fibroblast growth factor (FGF). The optimum pH for this drug is at 7.0.</p>

<p>Please enquire for more information about H-Gly-Gly-bNA·HBr including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Z-Glu-Tyr-OH is a disulfide bond with a cavity. It is soluble in acidic solutions and has a cationic surface. Z-Glu-Tyr-OH is an enzyme inhibitor that blocks the activity of α subunit of protein kinase C, which is involved in intracellular signal transduction pathways. The inhibition of this enzyme may lead to apoptosis, or programmed cell death. Z-Glu-Tyr-OH also inhibits fatty acid synthesis by blocking the activity of hydroxylase enzymes, such as 3β-hydroxysteroid dehydrogenase and 17α-hydroxylase. This compound has been shown to inhibit indole-3-propionic acid production by inhibiting the kinetic and sephadex g-100 activities of the enzyme indoleamine 2,3 dioxygenase.</p>

<p>Please enquire for more information about H-Val-Lys-Lys-Arg-OH acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Tyr-Gln-Ser-Leu-Arg-Trp-NH2 acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Asn-Glu-Ala-Tyr-Val-His-Asp-Ala-Pro-Val-Arg-Ser-Leu-Asn is a cytosolic protein that is an inhibitor of protein synthesis. It has been shown to inhibit the activity of proteases, such as caspase 1, and to activate caspase 1. This inhibition is consequent to the inhibition of polypeptide chain elongation and may be due to the ability of HAAHTVHAAPVVAALAHPVKVALARGSRLEUANNSOH to bind to peptidyl transferase or other proteins involved in protein synthesis. HAAHTVHAAPVVAALAHPVKVALARGSRLEUANNSOH binds to primary keratinocytes and k562 cells more efficiently than it does to thp1 cells, suggesting that it may have a role in skin cancer.</p>

<p>Z-Asp-Glu-Val-Asp-chloromethylketone is a reactive compound that inhibits the activity of proteases and induces neuronal death. Z-Asp-Glu-Val-Asp-chloromethylketone has been shown to induce necrotic cell death in malignant brain cells and has neurotrophic properties. It also causes mitochondrial membrane depolarization, which leads to mitochondrial cytochrome c release and subsequent apoptosis. The reaction mechanism is still unclear but it may involve hydrogen bonding between the ketone group and the amide nitrogen atom of the aspartate residue.</p>

<p>4-Amino-5-methoxy-2-methylbenzenesulfonic acid is a compound that has been used as an additive to analytical reagents in order to improve their sensitivity. This compound is used as the sodium salt, which is water soluble and has a high degree of reproducibility. 4-Amino-5-methoxy-2-methylbenzenesulfonic acid has also been used for the validation of analytical methods, including calibration and cytotoxicity testing. The validation procedure includes colorants, spectra analysis, impurities, and solvents.</p>

<p>Please enquire for more information about SPLUNC1 (22-39) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Hyp (Bzl)-OH·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fmoc-Phe-Wang resin (100-200 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Arg8)-Conopressin G trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(R)-2-Methylmorpholine is a protease inhibitor that has been shown to inhibit HIV-1 protease, a class of enzymes that are involved in the replication of HIV-1. It is used as a research tool to study the structure and function of HIV-1 protease. (R)-2-Methylmorpholine binds to the active site of the enzyme by forming hydrophobic interactions with residues in the active site. This binding leads to an inhibitory effect on ligand binding, protein synthesis, and other cellular processes. Molecular modeling studies have shown that (R)-2-Methylmorpholine inhibits HIV-1 protease by blocking the catalytic cleft and preventing access to substrate residues.</p>

<p>Please enquire for more information about Z-Arg(Mtr)-OtBu including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Please enquire for more information about (Gly14)-Humanin (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-D-Ala-D-Ala-bNA·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Bromo-1-methylindazole is an industrial chemical that can be synthesized by the reaction of formate, methanol, and indazole. The synthesis method involves the esterification of methyl formate with indazole to produce 6-bromo-1-methylindazole. It can also be synthesized by the annulation of methyl formate and cyclopentadiene followed by hydrolysis. This chemical has several isomers that are distinguished from each other based on their synthesis methods. 6-Bromo-1-methylindazole has been shown to have a hydrolysis reaction when it reacts with water, producing methyl bromide and hydrogen bromide.</p>

<p>Please enquire for more information about (His32,Leu34)-Neuropeptide Y (32-36) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Trt-Cys(Trt)-OH is a selective dicyclohexyl carbodiimide reagent for the synthesis of amides from carboxylic acids. It is used as an intermediate in the synthesis of glutathione and other nitrogen-containing compounds. Trt-Cys(Trt)-OH reacts with hydrochloric acid to form a salt, which can be saponified to release the desired product. The hydrochloric acid converts the ester into a carboxylic acid, while the amine group on the glycine reacts with the carboxylic acid to form an amide. Trityl is also produced during this reaction, which can be removed by reduction with hydrogen gas and palladium on charcoal.</p>

<p>Please enquire for more information about (D-Trp6)-LHRH acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Polymyxin B is a cationic detergent that binds to bacterial membranes and destroys the cell wall. Polymyxin B has been shown to be a potent antagonist of spermatozoa and microglia, which are cells that maintain the homeostasis of the central nervous system. It also has been shown to be an inhibitor of chemotaxis in polymorphonuclear leucocytes (PMN), which are white blood cells that participate in inflammatory processes. Polymyxin B has been shown to have chemotactic activity for PMN and inhibit protein synthesis in mitochondria. This compound also inhibits chelerythrine, a cyclase inhibitor that is used as an antineoplastic agent.</p>

<p>Epsilon-Maleimidocaproic acid-(2-nitro-4-sulfo)-phenyl ester·sodium salt (EMAP) is a crosslinker that belongs to the group of heterobifunctional reagents. It has been used to conjugate monoclonal antibodies with other molecules, such as toxins. EMAP is activated by the dianion generated by protonation of the nitro groups on the phenyl ring and reacts with free amines or thiols in proteins. EMAP can be used for labeling immunotoxins for diagnostic use, maximizing detection sensitivity, and crosslinking DNA molecules for use in molecular cloning experiments.</p>

<p>pTH (1-31) amide is a polymer conjugate that is used to treat osteoporosis. It has been shown to be effective in reducing the risk of fracture and increasing bone mineral density in animals. The compound binds to the extracellular domain of the estrogen receptor, altering its conformation and preventing it from interacting with other proteins in the nucleus. pTH (1-31) amide has also been shown to reduce blood pressure in animals by inhibiting angiotensin-converting enzyme. Clinical data on this drug are limited, but it has been well tolerated so far.</p>

<p>Angiotensin II is a peptide hormone that is involved in the regulation of blood pressure, water and electrolyte balance, and vascular resistance. It also plays a role in the development of angiogenic diseases such as cancer. Angiotensin II is an antagonist at the AT1 receptor, which is found on many tissues, including those in the brain, kidney, and vasculature. In addition to its effects on blood pressure and fluid retention, angiotensin II has been shown to affect intestinal motility and ileal absorption in rats. The inhibition of angiotensin II could be used for the treatment of neovascular diseases such as cancer.</p>

<p>Please enquire for more information about CRAMP (mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Lys(Abz)-Pro-Pro-pNA is a potent and selective DPP-IV inhibitor that has been shown to be active in humans. This drug binds to the DPP-IV enzyme and prevents it from breaking down the incretin hormone, GLP-1, which is released by the intestine in response to food intake. This leads to increased insulin production and an improved glycemic profile in people with type 2 diabetes. H-Lys(Abz)-Pro-Pro-pNA also inhibits endoproteolysis of dipeptidyl peptidase IV (DPPIV), which reduces its activity against other enzymes such as amyloid beta protein precursor protein (APP) and angiotensin II receptor type 1 (AT1R).</p>

<p>Please enquire for more information about H-D-Ala-Gln-octadecyl ester·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>MeOSuc-Ala-Ala-Pro-Ala-chloromethylketone is a peptidyl substrate for the enzyme carboxypeptidase A. This substrate has a high specificity for carboxypeptidase A and does not bind to other enzymes such as carboxypeptidase B, D, or L. The hydrophobic nature of this substrate has been shown in both hamsters and macaques. MeOSuc-Ala-Ala-Pro-Ala-chloromethylketone also shows cardiovascular effects in both animal models. It is possible that this effect is due to the proteolytic activity of the enzyme. More research needs to be done to identify the sequence of this peptide and how it may affect humans.</p>

<p>H-D-Ala-Gln-OH is a modified structural analog of l-fucose that has been shown to be a potent immunostimulant in vitro. The hydrocarbon chain on this molecule is substituted with an H-D-Ala moiety, which provides the molecule with a hydroxyl group. This modification increases the solubility of the molecule, thereby making it more suitable for in vivo administration. Additionally, modifications to the hydrocarbon chain may have functional consequences on the molecule's activity (e.g., substitutions may increase or decrease its ability to induce interleukin).</p>

<p>Adipokinetic hormone G is a peptide found in the hemolymph of Gryllus bimaculatus, a species of cricket. It has been shown to have anti-lipemic and antilipaemic effects in animal models. Adipokinetic hormone G can be detected by bioassay and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry.</p>

<p>D-Val-Leu-Lys-p-nitroanilide is a selective colorimetric substrate for plasmin used to determine plasmin formation from plasminogen in amidolytic activity assays and plasminogen activating assays. Plasmin is a plasma serine protease whose main role is to dissolve fibrin blood clots. After cleavage by plasmin, the protease activity is quantified by the release of p-nitroaniline (pNA) from the substrate.</p>

<p>Please enquire for more information about H-Phe-Pro-Ala-pNA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>BAM-3200 is a small molecule with the chemical formula CHFOC(O)NHCHCOOH. It is a potent and selective agonist of the TrkB receptor, which binds to brain-derived neurotrophic factor (BDNF). BAM-3200 has been shown to have anti-cancer activity in mouse tumor models, as well as increased locomotor activity and improved memory retention in mice. The biological function of BAM-3200 is not yet known. Structural analysis shows that it binds to the hydroxyl group on mammalian tissue receptors, which may be due to its basic protein structure. BAM-3200 also has been shown to hydrolyze enzymes such as esterases, glucuronidases, or glutathione reductase. This agent has been shown to be selectively active against cancer cells by binding to their acidic surface structures and altering their acidity.</p>

<p>Please enquire for more information about Amyloid beta-Protein (1-37) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Nalpha-(5-fluoro-2,4-dinitrophenyl)-D-leucinamide is a chemical compound that inhibits the activity of proteases. It has been shown to inhibit leukemia cells and actinomycetes. This chemical binds to the active site of proteases, inhibiting the hydrolysis of peptides by blocking the access of water molecules to the reactive site. In addition, Nalpha-(5-fluoro-2,4-dinitrophenyl)-D-leucinamide can also be used as a fluorescent probe for protease activity in analytical methods. The product research on this compound has shown that it is a potent inhibitor of cyclic peptide synthetases and can be used as an anti-inflammatory agent.</p>

<p>Please enquire for more information about H-Trp(Boc)-2-chlorotrityl resin (200-400 mesh) (Low Substitution) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>