Acides aminés (AA)

Applications Cucumopine is used in biological studies to evaluate Agrobacterium rhizogenes cucumopine strain T-DNA ORF8 and its effects on transgenic tobacco root cultures.
References Bonfill, M., et al.: Curr. Top. Plant Biol., 3, 223 (2002);

Applications 2-Methoxyphenol-3,4,5,6-d4 (CAS# 7329-52-4) is a useful isotopically labeled research compound.

Applications L-Serine is used in the synthesis of purines and pyrimidines as antibacterial/antifungal agents, as well as acting as a proteinogenic compound.
References Olivella, M. et al.: Bioorg. Med. Chem., 20, 6109 (2012);

Applications 8-Nitroguanine as a potential biomarker for progression of malignant fibrous histiocytoma, a model of inflammation-related cancer.
References Surh, Y., et al.: Mutat. Res., 480, 243 (2001), Balkwill, F., et al.: Lancet, 357, 539 (2001), Kawanishi, S., et al.: Biol. Chem., 387, 365 (2006), Hoki, Y., et al.: Cancer Sci., 98, 163 (2007),

Applications H-PRO-GLU-OH (cas# 67644-00-2) is a useful research chemical.

Applications 2-Methyl-1-phenyl-1-propene can be used in analytical study of analysis and comparison of aroma compounds from traditional Tangshan sorghum liquor and samples of improved fermentation process by GC-​MS.
References Jiang, X., et al.: Shipin Gongye Keji, 37, 87 (2016)

Applications N-Acetyl-L-Tryptophan, is a derivative of L-Tryptophan (T947210), that can be used as competitive inhibitor to identify and characterize tryptophanases. It can also be used as an NK1 tachykinin receptor antagonist, that may help to develop a novel therapeutic intervention for the treatment of reperfusion injury in acute ischemic stroke.
References Turner, R. J., et al.: Neuroscience, 220, 1 (2012);

Applications Isotope labelled Intermediate for transsulfuration whereby a mammal transfers the sulfur of methionine via homocysteine to cysteine.
References Thompson, J.W., et al.: J. Biol. Chem., 266, 17011 (1991), Yoshida, Y., et al.: Microbiol., 148, 3961 (2002), Jiracek, J., et al.: J. Med. Chem., 49, 3982 (2006),

Applications 2-Azido-2-deoxy-D-glucose is a glucose derivative that have been used to study the substrate specificity of galactokinase.
References Zou, W., et al.: Bioorg. Med. Chem. Lett., 22, 3540 (2012);

Applications VINYLTRIS(2-METHOXYETHOXY)SILANE (cas# 1067-53-4) is a useful research chemical.

Applications 2,4-Dinitrophenylhydrazone (DNPH) derivative.
References Lindsay, R.C., et al.: J. Food Sci., 29, 266 (1964),

Stability Hygroscopic
Applications A metabolite of 1-methyl-2-thioimidazole (methimazole). It inhibits bone resorption.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Paterson, J.R., et al.: Biochem. Biophys. Res. Comm., 116, 449 (1983), Taurog, A., et al.: Endocrinology, 124, 30 (1989).

Applications Intermediate for the preparation of Glimepiride.

Applications N-t-Boc-2-bromoethylamine (Technical grade, ~90%) (cas# 39684-80-5) is a compound useful in organic synthesis.

Stability Hygroscopic
Applications 4-Chloro-2-methylaniline Hydrochloride (cas# 3165-93-3) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-METHOXY-4-METHYLANILINE (cas# 39538-68-6) is a useful research chemical.

Applications Useful intermediate for the synthesis of a variety of chiral aminopiperidinyl quinolones as potent antibacterial agents against resistant pathogens; and alkynylpyrimidine amide derivatives as orally available inhibitors of Tie-2 kinase.
References Hu, X., et al.: J. Med. Chem., 46, 3655 (2003), Cee, V., et al.: J. Med. Chem., 50, 627 (2007),

Stability Hygroscopic
Applications 3-Methyl-2-oxobutyric acid calcium salt (cas# 51828-94-5) is a useful research chemical.

Stability Hygroscopic
Applications 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is used as a reagent in the synthesis of N-(2-acylaminobenzyl or 2-acylaminoheterocyclylmethyl)thiophene-2-carboxamide derivatives as antithrombotics. It is also used as a reagent in the synthesis of diamide derivatives as FXa inhibitors. 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is an intermediate for Edoxaban (E555520).
References Mochizuki, A., et al.: Jpn. Kokai Tokkyo Koho. JP 2010120852 A 20100603. Jun 3, 2010; Mochizuki, A., et al.: PCT Int. Appl. WO 2008123017 A1 20081016. Oct 16, 2008

Applications Indole-3-acetyl-L-phenylalanine is an indole-3-acetyl-amino acid conjugate involved in regulatory mechanisms for the control of auxin activity during physiological and pathophysiological responses.
References Ostrowski, M., et al.: J Plant Physiol, 191, 63-72 (2016)

Applications Calcium D-gluconate monohydrate (cas# 66905-23-5) is a useful research chemical.

Applications N-Boc-L-glutamic Acid 5-Methyl Ester is an intermediate used in the synthesis of Isodesmosine Chloride Hydrate (Synthetic) (I815051), which is a component of elastin and also it is extremely hygroscopic and must be stored over a desiccant such as silica gel.
References Partridge, S., et al.: Nature, 209, 399 (1966)

Applications 3-Formyl-5-methylbenzoic Acid

Applications: 3-Methyl-2,5-dihydrothiophene-1,1-dioxide is a reagent used in Diels-Alder reactions of butadienylpyridinium bromides.
References Lee, S., et al.: J. Org. Chem., 62, 7812 (1997);

Applications A labelled derivative of Dibarbituric acid.
References Hitchings, G.H., et al.: J. Biol. Chem., 177, 357 (1949),

Applications 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine is an intermediate used to prepare nonracemic γ-bicyclic heteroarylpiperazine- and heteroarylpiperidine-substituted prolinylthiazolidines as selective and orally active dipeptidylpeptidase 4 inhibitors for use as antidiabetic agents.
References Yoshida, T., et al.: Bioorg. Med. Chem., 20, 5705 (2012)