Acides aminés (AA)

<p>Applications An antibody agent.<br>References Rowell, F. J., et al.: Immunochemistry, 13, 891 (1976),<br></p>

<p>Applications 2,3-Dihydroxy-2-methylbutanoic Acid Sodium Salt is a useful research chemical.<br></p>

<p>Applications N'-tert-Butyl-3-methoxy-2-methylbenzohydrazide is an intermediate used in the synthesis of methoxyfenozide; an active ingredient for the commercial production of certain insecticidal and pesticidal formulations.<br>References Shao, J., et al.: Xiandai Nongyao, 2, 12, (2003), Mao, W. T., et al.: Chin. Chem. Lett., 23, 1233 (2012)<br></p>

<p>Applications 3-N-Methyl-L-histidine is a potential compound to be used as a treatment with pharmacological PPARα agonists to stimulate the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeletal muscle of rodents.<br>References Ringseis, R., et al.: Biochem. Biphys. Gen. Subject., 1830, 2105 (2013); Ubhi, B.K., et al.: Molec. Biosys., 8, 3125 (2012);<br></p>

<p>Applications Labelled L-Methionine, an essential aminoacid for human development. Hepatoprotectant; antidote (acetominophen poisoning); urinary acidifier.<br>References Benevenga, N.J., et al.: J. Agric. Food Chem., 22, 2 (1974), Fleisher, L.D., et al.: Clin. Endocrinol. Metab., 3, 37 (1974), Meinnel, T., et al.: Biochimie, 75, 1061 (1993),<br></p>

<p>Applications S-Phenylmercapturic Acid-d5 is the labelled analogue of S-Phenylmercapturic Acid (P335600), an important metabolite of Benzene.<br>References Qu, Q., et al.: Am. J. Ind. Med., 37, 522 (2000); Ghittori, S., et al.: Int. Arch. Occup. Environ. Health, 67, 195 (1995);<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-chloro-5-fluoro-2-methoxypyrimidine (cas# 1801-06-5) is a useful research chemical.<br></p>

<p>Applications 3-Methyl-thiopropanal is used as an analytical standard for the quanitiative determination of 2-Furfurylthiol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sen, A. and Grosch, W.: Z. lebensm Unters Forsch, 192, 541 (1991)<br></p>

<p>Applications N-Acetyl-L-phenylalanine is an protected analogue of L-Phenylalanine (P319415), an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.<br>References Sriram, S., et al.: J. Med. Chem., 56, 2540 (2013); Parker, B.M., et al.: J. Biotech., 155, 396 (2011);<br></p>

<p>Applications 3-Methoxycatechol is used to prepare polyphenolic deoxybenzoins as potential antioxidants and tyrosinase inhibitors.<br>References Ng, L., et al.: Bioorg. Med. Chem., 17, 4360 (2009)<br></p>

<p>Applications 3,5-Dichloro-4-methylaniline<br></p>

<p>Applications Ethylenediaminetetraacetic Acid-d16 (CAS# 203805-96-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications δ-Valerolactam-d4 is a labeled analog of δ-Valerolactam (V091440), which is a useful synthetic intermediate. It is an intermediate used to synthesize Cenicriviroc (C256550), an experimental drug candidate for the treatment of HIV infection. It is also a starting material for a new route to hexahydrojulolidines, using intramolecular 1,4-cycloaddition.<br>References Potts, K., et al. J. Org. Chem., 58, 5040 (1993); Klibanov, O., et al.: Curr. Opinion Invest. Drugs, 11, 940 (2010);<br></p>

<p>Applications D-LEUCYL-L-TYROSINE (cas# 3303-29-5) is a useful research chemical.<br></p>

<p>Applications Pteroyltri-γ-L-glutamic acid is a folate derivative found in various foods such as yeast, spinach, beef liver, beef fillet and peas.<br>References Tamura, T., et al.: Br. J. Haematol., 25, 513 (1973); Ndaw, S., et al.: J. Chromatogr. A, 928, 77 (2001)<br></p>

<p>Applications A protected glutamic acid for use in peptide synthesis.<br>References Takahashi, M., et al.: J. Exp. Biol., 200, 401 (1997), Michaelis, E., et al.: Prog. Neurobiol., 54, 369 (1998), Koch, H., et al.: Mol. Pharmacol., 55, 1044 (1999), O'Kane, R., et al.: J. Biol. Chem., 274, 31891 (1999),<br></p>

<p>Stability Air Sensitive<br>Applications A metabolite of Methyl Isocyanate.<br>References Slatter, J. G., et al.: Chem. Res. Toxicol., 4, 157 (1991),<br></p>

<p>Applications Fmoc-Ser(TBDMS)-OH (cas# 146346-81-8) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Ferrous Bisglycinate is used in the fortification of infant formulations and foods.<br>References Fox, T. et al.: Am. J. Clin. Nutri., 67, 664 (1998); Heath, A. et al.: J. Am. Coll. Nutr., 20, 477 (2001);<br></p>

<p>Applications L-3-Benzothienylalanine<br></p>

<p>Applications 3-Methoxy-1,2-propanediol is used to prepare phosphorothioate analogs of sn-2 radyl lysophosphatidic acid as metabolically stabilized LPA receptor agonists. It is also used to synthesize diacylglycerol analogs as potential second-messenger antagonists.<br>References Jiang, G., et al.: Bioorg. Med. Chem. Lett., 23, 1865 (2013); Briggs, J., et al.: Bioorg. Med. Chem. Lett., 2, 127 (1992)<br></p>

<p>Applications Potassium 2-hydroxy-4-methoxybenzoate (cas# 152312-71-5) is a useful research chemical.<br></p>

<p>Applications Acetyl-L-carnitine is a mitochondrial metabolite that helps to transport fatty acids into the mitochondria for energy (1). Acetyl-L-carnitine also upregulate metabotropic glutamate receptor 2 (mGlu2) via NF-κB p65 acetylation (2,3). It exhibits antidepressant and neuroprotective properties.<br>References (1) Stephens, F. B., et al.: J Physiol. 581, 431 (2007) (2) Wang, S. M., et al.: J Psychiatr Res. 53, 30 (2014) (3) Cuccurazzu, B., et al.: Neuropsychopharmacology 38, 2220 (2013)<br></p>

<p>Applications 4,4'-Methylenedianiline is used in the production of polyurethane foams and epoxy resins (1). Potential contributor in pulmonary arterial hypertension (PAH) in rats through alteration of the serotenergic transport system (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. Dyes and metabolites, Environmental Testing.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Hebert V. et al.: Cardiovas. Toxicol., 2011 Dec;11(4):316-24.2. Carroll-Turpin, M. et al.: Toxicol. Sci. 2015 Sep;147(1):235-45<br></p>

<p>Applications N-[(Benzyloxy)carbonyl]glycylglycine is a reagent in the synthesis of Glycylglycyl-L-tyrosine (G718500), which is a fungal tyrosinases and their capability to oxidize peptide-bound tyrosine residues is important in a view of applicability of tyrosinases.<br>References Bowness, J., et al.: Biochem. J., 53, 620 (1953), Cuff, M., et al.: J. Mol. Biol., 278, 855 (1998), Kubo, I., et al.: Bioorg. Med. Chem., 12, 5349 (2004),<br></p>

<p>Applications DMTMM, a conjugating agent that efficiently conjugat PnPS to Luminex microspheres without affecting the antigenicity of a broad set of PnPS.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wrzesien, J. &amp; Graham, D.: Tetrahedron, 68, 1230 (2012); Schlottmann, S. et al.: J. Im. Meth., 309, 75 (2006)<br></p>

<p>Applications L-Glutamic acid dibenzyl ester 4-toluenesulfonate<br></p>

<p>Applications 1,2:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose is a reagent in the synthesis of antibacterial/antifungal monosaccaride esters. Also used in the synthesis of antihyperlipidemic novel compounds involving glycosyl fructose derivatives.<br>References Shen, Y. et al.: Molecules, 17, 8661 (2012); Tiwari, P. et al.: Bioorg. Med. Chem. Lett., 16, 6028 (2006);<br></p>

<p>Applications 7-Chloro-8-methylquinoline (cas# 78941-93-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Ethyl-2-methyl-2-(3-methylbutyl)-oxazolidine is a oxazolidine-based moisture scavenger for use in urethane coatings, sealants and elastomers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Moisture sensitive<br>Applications Hexahydro-4-methylphthalic Anhydride, can be used in the mixture of other isomers nanofiber supported 3D interconnected BN nanosheets for epoxy nanocomposites with ultrahigh thermal management capability<br>References Chen, J., et al.: Adv. Funct. Material., 27, 5 (2017)<br></p>

<p>Lysyl-glutamic acid is a potent antagonist that blocks the activity of growth factor-β1, which is vital for the growth of gland cells. Lysyl-glutamic acid has also been shown to inhibit epidermal growth factor and activate tissue culture cells. This drug has also been shown to be carcinogenic in humans and animals, but not in vitro. It is metabolized by hydrolysis to lysine and glutamic acid. The chemical structures of lysyl-glutamic acid are very similar to those of the amino acids lysine and glutamic acid.</p>