Acides aminés (AA)

<p>Boc-D-Arg(Pmc)-OH is a triazole derivative that inhibits the production of proinflammatory cytokines. It is used as a therapeutic for premature infants to reduce the risk of infections, such as sepsis and meningitis. Boc-D-Arg(Pmc)-OH has been shown to inhibit interleukin 1 receptor (IL1R) and IL1β synthesis in human cells. Boc-D-Arg(Pmc)-OH binds to the triazole ring of IL1β, preventing the formation of an enzyme complex that is required for IL1β synthesis. This binding also prevents the formation of an enzyme complex that is required for IL1R synthesis. The conformation of the peptide chain may be important for its activity, with some stereoisomers being more potent than others.</p>

<p>Procollagen type I (212-216) H-Lys-Thr-Thr-Lys-Ser-OH is a tetrapeptide that is the most abundant component of human skin. It has been shown to have biological properties and can be synthesized in vitro. Procollagen type I (212-216) H-Lys-Thr-Thr-Lys-Ser-OH has an absorption maximum at 265 nm, which makes it suitable for use in uv protection creams. It also has a high chemical stability and can be stored for up to two years without degradation. Procollagen type I (212-216) H-Lys-Thr-Thr-Lys-Ser-OH is used as a substrate in cell culture to study protein synthesis and transcription, or polymerase chain reaction, technique. This peptide also inhibits the activity of proteases such as trypsin and chymotrypsin, making</p>

<p>H-DL-Val-Leu-Arg-pNA acetate salt is a natriuretic that is used to treat chronic kidney failure. It has an inhibitory effect on serine protease and epidermal growth factor, which are enzymes involved in the production of atrial natriuretic peptide (ANP). The drug also reduces blood pressure by inhibiting the activity of angiotensin II, which is a potent vasoconstrictor. H-DL-Val-Leu-Arg-pNA acetate salt has been shown to increase urea nitrogen levels by inhibiting the activity of alkaline phosphatase, which breaks down ammonia in the liver.</p>

<p>Please enquire for more information about Biotinyl-Obestatin (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Pro-His-Val-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Deamino-Phe19,D-Ala24,D-Pro26-psi(CH2NH)Phe27)-GRP (19-27) (human, porcine, canine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Arg13)-Amyloid b-Protein (1-40) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>[5-(5,6-Dimethyl-1,3-benzoxazol-2-yl)-2-methylphenyl]amine is a high quality chemical used in the research and development of new drugs. It is useful as a building block or intermediate for complex compounds, such as pharmaceuticals, agrochemicals, and dyes. It is also used as an intermediate to produce other chemicals with antimicrobial properties. This compound can be used in the production of many different types of products.</p>

<p>Boc-Ser(Leu-Fmoc)-OH is a peptide that has been synthesized using the Fmoc strategy. The peptide has been synthesized in an efficient manner and it is an epimer of Boc-Ser(Leu-OH).</p>

<p>H-Arg-Arg-Glu-Glu-Glu-Thr-Glu-Glu-Glu-OH is a peptide that is an activator of casein kinase II. Casein kinase II is a serine/threonine protein kinase that plays an important role in the regulation of cell proliferation and differentiation, apoptosis, and immune response. It has been shown to be involved in restenosis after angioplasty, as well as in tumorigenesis and radiation therapy. H-Arg-Arg-Glu-Glu-Glu-Thr-Glu - Glu - Glu - OH has also been shown to inhibit the replication of influenza virus by interfering with viral transcription and viral maturation. This peptide has been used for the treatment of alopecia, which may be due to its ability to inhibit hair follicle growth.</p>

<p>IDR-1 is a peptide that is derived from the sequence of the human typhimurium protein. IDR-1 has been shown to have anti-inflammatory properties and modulates immune responses in mice. In particular, IDR-1 inhibits neutrophil chemotaxis by inhibiting formyl peptide receptor signaling. This peptide also inhibits bacterial chemokines, which are important for the recruitment of neutrophils. IDR-1 also has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and pertussis.</p>

<p>Please enquire for more information about O-Hippuryl-DL-b-phenyllactic acid sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about HIV-1 gag Protein p24 (65-73) (isolates MAL/U455) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Ile-Arg-Pro-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Ala-Val-NH2·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about Boc-Ile-PAM resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>DL-Phenylalaninol is a chemical compound with the molecular formula CHNO. It is a white to pale yellow solid that is soluble in water and methanol, but not in diethyl ether. DL-Phenylalaninol has been synthesized by reacting cycloleucine with l-phenylalaninol. The reaction solution was heated at a temperature of 140°C for six hours, which yielded DL-Phenylalaninol as a hydroxy methyl compound. The synthesis of DL-Phenylalaninol was achieved through an asymmetric synthesis with sodium dodecyl sulfate surfactant. A detection sensitivity of 1 ppm and an enhancement at 260 nm were observed when analyzing the product by high performance liquid chromatography (HPLC).</p>

<p>Please enquire for more information about Z-Arg-p-nitrobenzyl ester mixture of hydrochloride and hydrobromide salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Intermediate in the synthesis of osimertinib (AZD9291)</p>

<p>D-Ala2,N-Me-Phe4,methionin(O)-ol5)-Enkephalin trifluoroacetate salt H-Tyr-D-Ala-Gly-N-Me-Phe-methionin(O)-ol trifluoroacetate salt is an analog of the endocannabinoid neurotransmitter, anandamide. It has been shown to be effective in the treatment of autoimmune diseases such as multiple sclerosis and inflammatory bowel disease. D-(3R)-3-[(1S,2R,3R,5R) -3-[2-(2,6 dichlorophenyl)ethenyl] -1H -indole]-1 -butanamine trifluoroacetate salt has been shown to inhibit the replication of a number of viruses including human immunodeficiency virus type 1 (HIV). This drug also inhibits the growth of organisms that are resistant</p>

<p>Tenofovir is a nucleoside analog reverse transcriptase inhibitor that binds to the RNA-dependent polymerase. This compound is used in combination with other antiviral agents for the treatment of HIV-1 infection and for prophylaxis against HIV-1 infection. Tenofovir has been shown to be effective against infections caused by strains of HIV-1, such as the drug resistant virus. Tenofovir is absorbed rapidly after oral administration, with a bioavailability of over 80%. The prodrug fumarate is hydrolyzed to tenofovir in vivo and this conversion occurs more efficiently in acidic conditions. Alafenamide, a prodrug of tenofovir, has been approved by the FDA as an alternative to tenofovir disoproxil fumarate (TDF) for the treatment of HIV-1 infection. Alafenamide is an acyclic nucleoside phosphonate that inhibits viral replication by inhibiting reverse</p>

<p>Please enquire for more information about Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fmoc-Val-Wang resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Angiotensin II receptor ligand nicotinoyl-tyrosine-arginine-proline-ile (ANGII) is a peptide that acts as a potent angiotensin II receptor agonist. It can be used to anesthetize rats and cause bradykinin b2 receptor activation. ANGII has been shown to inhibit the growth of several types of tumors, such as human melanoma cells, in animal experiments. This drug also has antiangiogenic properties, which may be due to its ability to induce the production of tumor necrosis factor-α (TNF-α).</p>

<p>Please enquire for more information about MeOSuc-Val-Val-Ile-Ala-pNA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Muramyl dipeptide (MDP) is a cell-wall constituent of Mycobacterium tuberculosis, which induces an antibody response. Muramyl tripeptide (MTP) is a modified form of MDP that has been used as a vaccine adjuvant. Ac-muramyl-Thr-D-Glu-NH2 is a specific antibody to MDP, which can be reconstituted by mixing with water and sodium chloride. It binds to the influenza virus, enhancing the immune response. The flu virus contains an antigen that stimulates the production of antibodies against influenza virus, and it also contains amphipathic molecules that are responsible for receptor binding and fusion with cells in the respiratory system. Ac-muramyl-Thr-D-Glu-NH2 binds to these molecules and enhances their function by increasing the efficiency of antibody binding. This leads to increased viral clearance from the body and reduced symptoms associated with infection with influenza</p>

<p>Z-Lys(Z)-ONp is an intermediate in the synthesis of lysergic acid diethylamide (LSD). It is a hypotensive agent that has analgesic properties. Z-Lys(Z)-ONp has been patented for use as a hypotensive agent, although it has not yet been approved for this use.</p>

<p>Z-Phe-His-Leu-OH is a monoclonal antibody that is used in the diagnosis and treatment of prostate cancer. This drug binds to the extracellular domain of the human prostate epithelial cell antigen (PSA), which is overexpressed in prostate cancers. Z-Phe-His-Leu-OH can be used in combination with other drugs for the treatment of prostate hyperplasia, such as angiotensin II receptor antagonists or 5α reductase inhibitors. The conformational epitope of this antibody has been demonstrated by immunohistochemical analysis on human tissues.</p>

<p>Please enquire for more information about 4-(Benzyloxy)-N,N-dimethyl-indole-3-glyoxylamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Urechistachykinin I is a diagnostic agent that has been used to detect the presence of bacteria in human serum. It is a peptide analog that is derived from the amino acid sequence of urechistachykinin and has been shown to have receptor activity for inflammatory diseases. The urechistachykinin I molecule can be conjugated with an antibody or other reactive molecule, which allows for its detection in biological fluids. <br>Urechistachykinin I has been shown to inhibit the growth of stenotrophomonas maltophilia, and can be used as a diagnostic agent for this bacterial infection.</p>

<p>PACAP-38 is a peptide that has been shown to have a variety of physiological effects, including the regulation of brain functions and immunological responses. PACAP-38 has been found to bind to toll-like receptor 4 (TLR4) in macrophages and neutrophils, which stimulates the production of proinflammatory cytokines. It also interacts with adenylate cyclase, which leads to an increase in cAMP levels. This may be the mechanism by which PACAP-38 regulates brain functions. The biological function of PACAP-38 is not yet clear but it may act as a signal peptide, regulating protein synthesis and gene expression.</p>

<p>Component of snake venom; part of a family of vasoconstrictor isopeptides</p>

<p>Nazumamide A is a cyclic peptide with inhibitory activity against serine proteases. It binds to the active site of thrombin and inhibits its action, thereby inhibiting the fibrinogen degradation in blood. Nazumamide A is also found to have neuroprotective properties, which may be due to its ability to inhibit nitric oxide production by binding to the enzyme nitric oxide synthase. It has been shown to have anti-inflammatory activities and can be used for the treatment of inflammation-associated diseases such as asthma and arthritis. Nazumamide A is a nonribosomal peptide that does not require any cofactors for synthesis.</p>

<p>4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid is an organic compound. It is a white solid that is insoluble in water but soluble in organic solvents. The molecule has a molecular weight of 224.8 g/mol and contains a carbonyl group and amine functional groups. 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid can be prepared by the acylation of 4-(aminomethyl)-benzoic acid with imidazole hydrochloride in the presence of sodium carbonate as a base.</p>

<p>Please enquire for more information about Biotinyl-Amylin (mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about FA-Ala-OSu including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Suc-Ala-Pro-Ala-AMC is a synthetic peptide that is used as a fluorescent substrate to measure the activity of serine proteases. It is used in plant physiology and has been shown to be effective in the treatment of inflammatory diseases. Suc-Ala-Pro-Ala-AMC is an acidic molecule with a pKa of 3.1. This means it can exist as both a zwitterion, with a positive charge on one end and negative charge on the other, or as an ionized molecule with both ends having a negative charge. The zwitterionic form is more stable than the ionized form at low pH levels and will therefore be present at higher concentrations at lower pH values. Suc-Ala-Pro-Ala-AMC shows proteolytic activity against peptidases such as papain, bromelain, trypsin, and chymotrypsin. It also binds to neutroph</p>

<p>Please enquire for more information about Z-Phe-Gly-Phe-Gly-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-D-Ile-Asp-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Intermediate in the synthesis of idelalisib (CAL 101)</p>

<p>H-Trp-Gly-Tyr-OH is a carbohydrate binding molecule that has been shown to have an anhydrase activity. It also has sequences with homologous enzymes in other organisms, such as multienzyme and chromatographic enzymes. This molecule is soluble in water and insoluble in organic solvents. H-Trp-Gly-Tyr-OH binds to hemicellulosic carbohydrates and catarrhine carbonic anhydrase, which are found only in higher primates. Mutational analysis has shown that the H-Trp-Gly-Tyr-OH protein can be converted into a cyclopentadienyl derivative, which is not found in nature.</p>

<p>Please enquire for more information about Fmoc-D-Ser(BSi)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Lys1015·1024)-Thrombospondin-1 (1015-1024) (human, bovine, mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Sorbin (147-153) amide (porcine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about FA-Lys-Leu-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

4-Bromo-2-methylbut-1-ene is an alkylating agent that reacts with DNA, RNA and proteins. It has been shown to be effective in the treatment of bladder cancer. 4-Bromo-2-methylbut-1-ene is used as a trifluoride source for boron trifluoride etherate, which is then reacted with plant tissues. This reaction yields a prenyl group, which can be further processed to yield an alkynyl group. The alkynyl group can be reacted with anhydrous sodium to form a chloride salt. This salt can then react with carbon monoxide to form a carbone molecule, which is the final product of this chemical process.

<p>Please enquire for more information about (Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-(2R,3S)-Phenylisoserine is a chiral enantiomer that can be used in organic synthesis. It is a reactive compound and has the ability to form amide bonds with other compounds. 3-(2R,3S)-Phenylisoserine is also able to react with nitro groups and form an oxime. It is not soluble in water but it is soluble in organic solvents like acetone or methanol. 3-(2R,3S)-Phenylisoserine can be synthesized by the enzymatic methods of benzyloxymethyl hydrazine and hydrochloric acid.</p>

<p>Caspase-3/7 Inhibitor II Ac-Asp-Asn-Leu-Asp-aldehyde (pseudo acid) is a peptide inhibitor of caspases. It blocks the activation of these proteases and their subsequent cleavage of substrates in the apoptotic pathway. This drug has potent inhibitory activity against caspases 3, 7, 8, 9, and 10. Caspase-3/7 Inhibitor II Ac-Asp-Asn-Leu-Asp-aldehyde (pseudo acid) specifically interacts with the active site and inhibits the enzyme by binding to an aspartic acid residue at position D197 in human caspase 3. Caspase 3/7 Inhibitor II Ac-Asp-Asn-Leu-Asp-aldehyde (pseudo acid) is localized to mitochondria and binds to acetyldeviceine (acDEV), a substrate for caspases</p>

<p>Trans-4-hydroxy-L-proline methyl ester hydrochloride is a matrix metalloproteinase inhibitor. It inhibits the activity of matrix metalloproteinases, which are enzymes that break down collagen and other proteins in the extracellular matrix. The inhibition of these enzymes leads to a decrease in restenosis, which is the recurrence of artery narrowing after angioplasty or stent placement. Trans-4-hydroxy-L-proline methyl ester hydrochloride has been shown to be effective against chemokine receptors, including CCR5 receptor and chemokines such as TNFα. It also inhibits cytokine production by inhibiting signaling pathways that lead to inflammation and cell proliferation.</p>