Acides aminés (AA)

<p>H-Gly-Phe-Tyr-OH is a water soluble polymer that can be conjugated to drugs. The polymer is composed of methacrylamide and Gly, Phe, and Tyr residues. This polymer is used in the treatment of cancer by conjugating a drug to the polymer to make it water soluble. H-Gly-Phe-Tyr-OH can also be used as a polymeric carrier for docetaxel or gemcitabine.</p>

<p>Please enquire for more information about pTH (2-34) (human) acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Pro-Val-Gly-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ac-Arg-Leu-Arg-AMC trifluoroacetate salt is a mitochondrial biogenesis activator that has been shown to increase the levels of proteins in the mitochondria. These proteins are required for mitochondrial membrane potential, ATP production, and protein homeostasis. Ac-Arg-Leu-Arg-AMC trifluoroacetate salt has been shown to increase the number of pluripotency markers in human liver cells and to reduce insulin resistance in animals. The drug also increases the expression of ubiquitin ligases and proteasomes, which are enzymes that degrade damaged proteins. Ac-Arg-Leu-Arg-AMC trifluoroacetate salt may be used for treating liver diseases or disorders as well as obesity.</p>

<p>Glucagon is a peptide hormone that belongs to the group of vasoactive intestinal peptides. It is produced by the alpha cells of the pancreas and stimulates gluconeogenesis in the liver, thereby increasing blood glucose levels. Glucagon has also been shown to cause membrane hyperpolarization and cell death in cancer cells. Glucagon is a homologous protein that has been shown to have physiological effects similar to those of insulin, such as increased levels of cytosolic Ca2+ ions and camp levels. Glucagon binds to its receptor on the plasma membrane with high affinity, activating adenylate cyclase and phospholipase C, which leads to an increase in intracellular camp levels. This results in activation of protein kinase A (PKA), which phosphorylates proteins involved in glycogenolysis, glycolysis, and lipolysis. Glucagon also activates mitogen-activated protein kinases (MAPK</p>

<p>Please enquire for more information about KR-12 (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ac-Glu-Ser-Met-Asp-aldehyde is a molecule that is naturally produced by the human body. It has been shown to be an endogenous caspase activator, which may lead to apoptosis. Ac-Glu-Ser-Met-Asp-aldehyde can also bind to cholesterol and influence its synthesis, thus affecting the production of other proteins. This molecule has a protease activity and can cleave peptides at specific sites. The sequences of this molecule have been determined and it has been found that these sequences are similar to those found in other proteases such as serine proteases.</p>

<p>Please enquire for more information about Fmoc-D-Pen (Trt)-Wang resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Asp(OtBu)-2-chlorotrityl resin (200-400 mesh) (Low Substitution) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about H-D-Cys(4-methoxytrityl)-2-chlorotrityl resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Boc-Ala-Gly-OH is a synthetic chemotactic peptide. It was originally synthesized in the form of an N-terminal amide and conjugated to a variety of carrier proteins, including bovine serum albumin, ovalbumin, thyroglobulin, and keyhole limpet hemocyanin. Boc-Ala-Gly-OH has been shown to stimulate the growth of various cell types including platelets and erythrocytes, as well as to inhibit tumor growth.</p>

<p>Please enquire for more information about N-2-Ethoxyethyl-Val-Ala-anilide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Leu116)-Prepro-Neuromedin U (104-136) (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Mca-Pro-Lys-Pro-Leu-Ala-Leu-Dap (Dnp)-Ala-Arg-NH2 trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about [2,6-Dimethyl-4-(3-[2-(Z-amino)-ethylcarbamoyl]-propoxy)-benzenesulfonyl]-Dap (Boc)-OMe including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

H-Leu-Gly-Gly-OH is a protease enzyme that belongs to the family of hydrolases. It has been shown to have proteolytic activity with casein and protein synthesis with pancreatic enzymes. The kinetic data for this enzyme were determined by measuring the rate of hydrolysis at different pH levels. The optimum pH for this enzyme is 6.0, with a maximum activity at pH 7.5 and an inhibition at pH 4.0. This enzyme can be found in either the free form or as an integral membrane protein in lysosomes, where it exhibits high affinity for hydrogen bonds and low affinity for ionic bonds. H-Leu-Gly-Gly-OH is used in analytical methods such as chromatography and spectrophotometry to identify proteins in biological samples.END>

Suc-Ala-Phe-Pro-Phe-pNA is a recombinant isomerase that has been shown to be an immunosuppressive agent. It is able to catalyze the conversion of cyclosporin A into its two inactive forms, as well as the conversion of cyclophilins A and B into their corresponding inactive forms. The enzyme has also been shown to have chaperone activity. Suc-Ala-Phe-Pro-Phe-pNA has been expressed in Escherichia coli and purified from inclusion bodies using an affinity column with immobilized recombinant cyclophilin A and B. The enzyme's activity was measured by catalysis of the conversion of pNPP, a substrate analogue, into pNPPdG, which can be detected spectrophotometrically at a wavelength of 340 nm. Suc-Ala-Phe-Pro-Phe-pNA shows exponential growth in the presence of

<p>Please enquire for more information about (D-Thr6,D-Trp8·9,L-alaninol15)-Galanin (1-15) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Hippuryl-Phe-Arg-OH is a potent and selective inhibitor of angiotensin-converting enzyme (ACE) with a long duration of action. It has been shown to be a potentiator of captopril and enalaprilat in the biochemical validation for ACE inhibition. Hippuryl-Phe-Arg-OH has significant inhibitory activity against phosphatases such as carboxypeptidase A, phospholipase A2, and aminopeptidase N.</p>

<p>Please enquire for more information about Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about HIV Protease Substrate III-B (Native Sequence) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ac-Gly-Pro-AFC is a dipeptidyl peptidase inhibitor that inhibits the action of protein-degrading enzymes called peptidases. Ac-Gly-Pro-AFC has been shown to be effective in treating diabetes by inhibiting the activity of fibroblast activation protein, which is involved in the development of diabetes. Ac-Gly-Pro-AFC also has an inhibitory effect on the enzyme connect, which is involved in cellular proliferation and differentiation. Clinical trials have been conducted to evaluate the efficacy of this drug for treatment of diabetic nephropathy with promising results. Ac-Gly-Pro-AFC has also been shown to have a beneficial effect on collagen synthesis and inhibition of proinflammatory cytokine release from activated macrophages.</p>

<p>Annexin A1 (1-11) is a peptide that is part of the annexin family. It is involved in the degranulation of cells and inhibits inflammation by inhibiting the production of pro-inflammatory cytokines. Annexin A1 (1-11) has been shown to be an anti-inflammatory compound as it binds to phospholipids on the surface of neutrophils, leading to inhibition of their chemotaxis and phagocytosis. This peptide also interacts with other annexins and prevents apoptosis by blocking caspase activity. Finally, it has been found that annexin A1 (1-11) can promote the healing of wounds in mice by accelerating reepithelialization and reducing scar formation. The concentration required for these effects are nanomolar concentrations.</p>

<p>Please enquire for more information about H-D-Leu-pNA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Gly-Phe-NH2·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about C-Peptide 1 (rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (H-Cys-betaNA)2·2 HCl (Disulfide bond) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Ala-Thr-OH is a dipeptide that is used as a stabilizer for the active form of methionine in some nutritional supplements. H-Ala-Thr-OH is synthesized by the hydroxylation of DL-methionine, which is then converted to H-Ala-Thr-OH by an aminopeptidase. The amino acid sequence of H-Ala-Thr-OH resembles that of l-threonine, but lacks an α carbon atom and an amino group on the carboxylic acid end. This dipeptide has been shown to be auxotrophic for both lysine and threonine when expressed in Escherichia coli.</p>

<p>Please enquire for more information about 1b-(4-Fluorophenyl)hexahydro-',7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3] oxazine-3-butanoic Acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Gly-Met-Gly-OH is an amide containing a sulfoxide group. It is synthesized from the amino acid glycine and the tripeptide Met-Gly-Gly. The synthesis of HMG was first reported by Sato in 1907, although it was not used as a drug until 1983. This drug has potential antitumor activity and inhibits the growth of certain tumor cells. HMG is metabolized by peptidases, which hydrolyze the peptide bond between glycine and Met-Gly-Gly. Hydrolysis of HMG yields glyoxylic acid (H2O2) and the amino acids glycine and methanol. HMG also inhibits the uptake of glucose into cells, which may be related to its antitumor effect. X-ray diffraction studies have shown that HMG has a carboxylate group at C6 that binds to three oxygen atoms, which are present in two</p>

<p>HIV (gp41) Fragment H-Ala-Val-Gly-Ile-Gly-Ala-OH is a hydrophobic peptide fragment that is used as an antigen to induce immunity against HIV infection. The sequence of the peptide was obtained by sequencing the human immunodeficiency virus type 1 (HIV). The peptide contains glutamic acid and ornithine, which are necessary for the attachment of gp41 to the target cell surface and for the penetration of the virus into cells. The cyclic peptide induces mononuclear phagocytes to produce antibodies against gp41, which can inhibit infection by HIV.</p>

<p>Please enquire for more information about (D-Pro7)-Angiotensin I/II (1-7) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Tyr-Leptin (26-39) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Proadrenomedullin (1-20) is a polypeptide that is found in human plasma. It is a member of the vasoactive intestinal peptide family and has been shown to be involved in the regulation of vascular tone, blood pressure, and blood vessel permeability. Proadrenomedullin (1-20) also inhibits the production of proinflammatory cytokines such as tumor necrosis factor-alpha, interleukin-6, and interleukin-8. This compound has been shown to have antiviral activity against HIV and herpes simplex virus type 1. Proadrenomedullin (1-20) also functions as a growth factor for tumor cells.</p>

<p>H-Trp-Val-OH is a human protein that has been shown to be involved in the uptake of glucose into cells. H-Trp-Val-OH is also known as colony stimulating factor 1, which stimulates the growth and differentiation of hematopoietic cells. It has been shown to play a role in weight gain, insulin resistance, and type 2 diabetes. This monoclonal antibody has not been found to have any long term toxicity or genotoxicity in animal studies.</p>

<p>Boc-Gly-Phe-Gly-Lys-OH is an allergen that belongs to the group of flavonoids. It is a reaction product of cinnamates and methoxycinnamate, which are found in sunscreens. Boc-Gly-Phe-Gly-Lys-OH is used as a model for chemical carcinogens in studies on cancer. Boc-Gly-Phe-Gly-Lys-OH has been shown to be a potent skin cancer and radiation sensitizer. There are no known effects on humans, but it is possible that this compound may react with UV irradiation from sunlight, causing DNA damage and skin cancer.</p>

<p>Please enquire for more information about ([15N]Gly)-Glutathione (reduced) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fibronectin fragment (196-203) H-Ser-Arg-Asn-Arg-Cys-Asn-Asp-Gln, is a synthetic peptide that has been shown to have antiinflammatory properties. It can inhibit the inflammatory response by inhibiting the production of cytokines and chemokines. Fibronectin fragment (196-203) H-Ser-Arg-Asn-Arg-Cys-Asn, has also been shown to inhibit angiogenesis and tumor growth in vitro, as well as stabilize blood vessels and reduce the incidence of lymphatic vessel leakage. This peptide may be used in cancer therapy and for other diseases such as Kaposi's sarcoma, rheumatoid arthritis, autoimmune diseases, or infectious diseases.</p>

<p>Please enquire for more information about Glutaryl-Ala-Ala-Phe-4MbNA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Ala-Phe-NH2·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Lys3-Bombesin is a bifunctional peptide that binds to the bombesin receptor and is used in cancer therapy. It is a radiotracer, which can be used for diagnostic imaging and diagnosis of tumors. Lys3-Bombesin has a high affinity for the bombesin receptor subtype B, which is expressed by prostate cancer cells. The peptide can be conjugated to a small molecule, such as a radioactive isotope, and used to deliver it specifically to the tumor site. This compound has been shown to inhibit the growth of human prostate cancer cells in vitro.</p>

Please enquire for more information about Ac-Cys(dodecyl)-chloromethylketone including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about FMOC-D-CYS(TRT)-WANG RESIN - 200-400 mesh including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fmoc-D-proline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Axltide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Z-Leu-Arg-4MbNA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Boc-Thionoleu-1-(6-nitro)benzotriazolide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Boc-4-piperidineacetaldehyde is a chiral, stable, and readily available aldehyde. It has been used in the synthesis of various biologically active molecules including imidazolidinones, which are important for their use as catalysts in organic chemistry. The synthesis of this molecule by the condensation of 4-piperidineacetic acid with acetaldehyde followed by reduction with sodium borohydride is an example of this type of reaction. N-Boc-4-piperidineacetaldehyde can be used to synthesize imines and linkers that are covalently bonded to the protein backbone. This molecule also has conformational stability and is not susceptible to oxidation or radiation damage.</p>

<p>Please enquire for more information about Boc-Asp(OcHex)-OSu including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Z-Tyr-Val-Ala-DL-Asp-fluoromethylketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>