Acides aminés (AA)

<p>Please enquire for more information about Neuromedin S (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Suc-Ala-Phe-Pro-Phe-pNA is a recombinant isomerase that has been shown to be an immunosuppressive agent. It is able to catalyze the conversion of cyclosporin A into its two inactive forms, as well as the conversion of cyclophilins A and B into their corresponding inactive forms. The enzyme has also been shown to have chaperone activity. Suc-Ala-Phe-Pro-Phe-pNA has been expressed in Escherichia coli and purified from inclusion bodies using an affinity column with immobilized recombinant cyclophilin A and B. The enzyme's activity was measured by catalysis of the conversion of pNPP, a substrate analogue, into pNPPdG, which can be detected spectrophotometrically at a wavelength of 340 nm. Suc-Ala-Phe-Pro-Phe-pNA shows exponential growth in the presence of</p>

<p>3-Hydroxy-4-methyl-2-nitrobenzoic acid is an analog of the natural substrate for the enzyme nitroreductase. It can be used in oxidative coupling reactions to generate a covalently bonded product, which is immobilized on sepharose. 3-Hydroxy-4-methyl-2-nitrobenzoic acid has a high affinity for nucleic acids and can be used in biospecific assays. The chromophore of 3-hydroxy-4-methyl-2-nitrobenzoic acid is easily oxidized, leading to its use in nitroreduction reactions in which a nitro group is reduced to an amino group.</p>

<p>Please enquire for more information about HIV Protease Substrate III-B (Native Sequence) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Biotinyl-Substance P trifluoroacetate salt Biotinyl-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 trifluoroacetate salt is a biotin conjugated Substance P analog. It is designed to bind to the amino acid sequences in the brain that are responsible for controlling and regulating pain. The drug's amino acid sequence was designed by accessing databases of amino acid sequences from all known organisms. The drug is administered as a sequence of cassettes, each containing an acid molecule that can be transferred to cells through nucleotide transfer.</p>

<p>Please enquire for more information about Dynorphin A (1-13) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>IGF-I (1-3) H-Gly-Pro-Glu-OH is a synthetic peptide that has been shown to be effective in treating neuronal death caused by glutamate. It binds to calcium ions and inhibits the activity of gamma-aminobutyric acid, which is an inhibitory neurotransmitter. IGF-I (1-3) H-Gly-Pro-Glu-OH also blocks fatty acid synthesis, leading to necrotic cell death. In vitro assays have shown that this drug can protect against blood group O erythrocytes from pyridoxal phosphate oxidation and protocatechuic acid binding. This drug has also been shown to increase locomotor activity in mice, as well as improve motor function in rats with experimental stroke.<br>IGF-I (1-3) H-Gly-Pro-Glu-OH is synthesized using a polymerase chain reaction technique and consists of amino acids 1 through 3 of</p>

<p>Please enquire for more information about RVG-9R trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Disulfide bond is a protein that regulates muscle cell assembly and interactions. Disulfide bonds are formed by the oxidation of two cysteine molecules, which can be found in the extracellular matrix (ECM). The protein is an important regulator of metalloproteinases, which are enzymes that regulate ECM turnover. When disulfide bond lacks, it causes a deficiency in collagen production. Disulfide bond also has interactions with MMP-2, which plays a role in the regulation of arteriosclerosis and genetic disorders such as muscular dystrophy.</p>

<p>Please enquire for more information about Fmoc-D-Trp(Boc)-Wang resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Perfluoro-N-(4-methylcyclohexyl)piperidine (4-FPP) is a fluorine compound that has been shown to inhibit the enzymatic activity of tyrosine kinases. It is a potent inhibitor of both human and murine tyrosine kinases, but it does not bind to bacterial tyrosine kinase domains. 4-FPP has been used in clinical studies as an anti-cancer drug, although it's clinical relevance remains unclear. It has also been shown to be effective against the influenza virus by inhibiting the synthesis of viral proteins that are involved in replication. The chemical structure of 4-FPP contains a carbonyl group that can react with other compounds through a photochemical process. This reaction is thought to result in the development of new drugs with similar biochemical properties to 4-FPP.</p>

<p>Benzamidine is a benzamidase inhibitor that competitively binds to bacterial enzymes such as metalloendopeptidases and matrix metalloproteinases. It inhibits the degradation of collagen, resulting in a higher concentration of soluble extract. This drug also has an effect on spermatozoa, which may be due to its ability to inhibit bacterial enzymes that are involved with uptake and preload. Benzamidine has been shown to have a pH optimum of 8-9 and is most active at this pH range.</p>

<p>HIV (gp41) Fragment H-Ala-Val-Gly-Ile-Gly-Ala-OH is a hydrophobic peptide fragment that is used as an antigen to induce immunity against HIV infection. The sequence of the peptide was obtained by sequencing the human immunodeficiency virus type 1 (HIV). The peptide contains glutamic acid and ornithine, which are necessary for the attachment of gp41 to the target cell surface and for the penetration of the virus into cells. The cyclic peptide induces mononuclear phagocytes to produce antibodies against gp41, which can inhibit infection by HIV.</p>

<p>Acetate salt</p>

<p>Please enquire for more information about Z-Asp(OtBu)-ONp including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ne-Fmoc-L-lysine is an amine with a homopolypeptide backbone. It is insoluble in water and has a low profile. Ne-Fmoc-L-lysine is synthesized using solid phase chemistry, which can be used for the synthesis of nanocarriers. It has been shown to interact with other molecules such as polymers and proteins. Ne-Fmoc-L-lysine can also be used in supramolecular architectures and oriented microscopy techniques.</p>

<p>Please enquire for more information about H-Cys(Acm)-2-chlorotrityl resin (200-400 mesh) (Low Substitution) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Tyr-Leptin (26-39) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Angiotensin I/II (3-7) H-Val-Tyr-Ile-His-Pro-OH is an antagonist of the angiotensin II receptor. It has been shown to be a cognitive enhancer by statistically improving treatments for behavioural problems in rats and mice. Angiotensin I/II (3-7) H-Val-Tyr-Ile-His-Pro-OH has also been shown to inhibit nicotinic acetylcholine receptors, which are involved in mediating the effects of neurotransmitters on muscle cells. This agent also inhibits angiotensin II receptors, leading to vasodilation and reduced blood pressure. The mechanism of action is not yet clear but may involve inhibition of protein kinase C. In preclinical studies, it has been shown that this drug facilitates behavioural effects such as memory retention and motor performance in rats when given before treatment with peptides such as substance P or calcitonin gene related pept</p>

<p>Please enquire for more information about Band 3 Protein (824-829) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Anti-Kentsin trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(Benzyloxy)-N,N-dimethyl-indole-3-glyoxylamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Thr(tBu)-NH2·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Met(O)35)-Amyloid b-Protein (1-42) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>P-Methoxybenzylmercaptan is an inhibitor of protein synthesis. It binds to the active site of the enzyme ribonuclease A, which is involved in the processing of messenger RNA. P-Methoxybenzylmercaptan also inhibits other enzymes such as alkaline phosphatase and esterases. It has been shown to be effective against HIV infection. This compound can be used for chemical ligation reactions and as a cell culture medium additive, as it protects cells from oxidation and provides a more acidic environment. P-Methoxybenzylmercaptan has been shown to bind to amines and is being investigated for its use in drug development.</p>

<p>Z-Phe-Leu-Glu-pNA is a synthetic substrate for proteolytic enzymes. This peptide is an optimal substrate for polymerase chain reaction (PCR) due to its high concentration of serine and reactive site. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. This peptide has also been studied in clinical trials as a potential treatment for hormone disorders such as prostate cancer and breast cancer.</p>

<p>Please enquire for more information about Fmoc-Gly-Ser(Psi(Me ,Me)pro)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Anti-Inflammatory Peptide 3 (AIP3) is a peptide that contains an ester linkages and a carboxylic ester, which are both hydrophobic. The amino acid sequence of AIP3 is H-Met-Gln-Met-Asn-Lys-Val-Leu-Asp-Ser. AIP3 has been shown to have antiinflammatory properties and can be used as a diagnostic tool for inflammation. This peptide also has prodrug properties and can be conjugated with drugs to form drug linkers.</p>

<p>Polistes mastoparan is a peptide that was extracted from the venom of the European beewolf. It has been shown to have high affinity for tumor cells and can be used as a diagnostic agent. Polistes mastoparan has also been shown to have anti-inflammatory properties and inhibit the formation rate of glycopeptide antibiotics. This peptide can bind to calmodulin, which may be due to its β-amino acid sequence. Polistes mastoparan inhibits the growth of Stenotrophomonas maltophilia in vitro by binding to fatty acids on the cell membrane.</p>

<p>Please enquire for more information about Z-Leu-Arg-4MbNA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Z-Val-Ala-Asp-AMC is a photoactive peptide that is activated by light exposure. This drug has cytostatic and cardiotoxic effects, which may be due to its ability to induce autophagy. Z-Val-Ala-Asp-AMC induces cell death in cancer cells through the activation of caspase independent pathways. It also inhibits nitroprusside induced apoptosis in cultured skin cells, suggesting that it may have therapeutic potential for the treatment of cancer.</p>

<p>Bz-Asn-pNA is a peptide that is synthesized by the enzyme phosphoenolpyruvate carboxykinase. It has been shown to be an effective inhibitor of proteolytic enzymes, such as aminopeptidases. Bz-Asn-pNA has also been shown to be stable in high salt concentrations and its activity does not change at physiological pH levels. The kinetic constants for Bz-Asn-pNA have been determined using dodecylphosphocholine and endogenous substrate (3H)lysine. The optimum pH for Bz-Asn-pNA is between 7 and 8, which is optimal for protein synthesis.</p>

<p>Please enquire for more information about IGF-I Analog including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>AF-16 trifluoroacetate salt is a synthetic peptide, which is derived from chemical synthesis with tailored modifications to enhance its stability and efficacy. This compound acts by specifically binding to target receptors or proteins, facilitating the study of biochemical pathways and mechanisms at the molecular level. It is particularly used in biological and biochemical research settings to probe cellular processes, offering insights into protein interactions and signaling pathways.</p>

<p>Please enquire for more information about H-Thr-Thr-pNA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ((R)-4-Hydroxy-4-methyl-Orn7)-phalloidin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ac-Trp-Glu-His-Asp-aldehyde is a tetrapeptide that has been shown to inhibit the activity of caspases. Caspases are proteases that play an important role in cell death by inducing apoptosis and necrosis. The structure of the Ac-Trp-Glu-His-Asp-aldehyde was determined by X-ray crystallography, revealing a hydrophobic molecule with a pseudo acid residue. This compound binds to peptides and blocks the binding site for caspase substrates, which prevents their activation. Acetylation of this compound also increases its hydrophobicity, making it more likely to bind to other molecules such as proteins or lipids.</p>

<p>H-D-Ala-Gln-OH is a modified structural analog of l-fucose that has been shown to be a potent immunostimulant in vitro. The hydrocarbon chain on this molecule is substituted with an H-D-Ala moiety, which provides the molecule with a hydroxyl group. This modification increases the solubility of the molecule, thereby making it more suitable for in vivo administration. Additionally, modifications to the hydrocarbon chain may have functional consequences on the molecule's activity (e.g., substitutions may increase or decrease its ability to induce interleukin).</p>

<p>Neuromedin U-23 (rat) is a peptide that belongs to the family of tachykinins, which are small neuropeptides that act as neurotransmitters in the central nervous system. It is a potent stimulator of intestinal motility and has been shown to have protective effects against oxidative stress in cells. Neuromedin U-23 (rat) shares sequence similarity with human neuromedin N-19 and binds to the same receptors in the brain, suggesting it may have similar physiological effects. This peptide has been shown to inhibit tumor cell growth by inducing apoptosis, but it does not appear to have any effect on healthy cells.</p>

<p>FA-Phe-Phe-OH is a synthetic substrate for the polymerase chain reaction. It has been used in diagnostic tests to identify bacterial or viral infections and to diagnose cancer. This molecule is a mixture of three amino acids: phenylalanine, phenylalanine, and phenylalanine. FA-Phe-Phe-OH is not active against Gram-positive bacteria, but it can be used as an antibiotic against Gram-negative bacteria. The transport properties of this molecule have been shown to be radial and actin filament dependent because it binds to FtsZ proteins at the division site of the cell.</p>

<p>Please enquire for more information about (H-Cys-Phe-OH)2 (Disulfide bond) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Boc-Cys(Mob)-Merrifield resin (100-200 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Nitro-Z-Gly-Trp-Gly-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Endomorphin-2 is a cyclic peptide that is the endogenous ligand for the neurokinin-1 receptor and kappa-opioid receptors. It has been shown to have analgesic, anti-inflammatory, and antidiarrheal properties. Endomorphin-2 also has been shown to inhibit platelet aggregation and vasoconstriction in vivo. The biological activities of endomorphin-2 are similar to those of endomorphin-1, but it differs structurally in that it contains a single intramolecular hydrogen bond between the amide nitrogen of Tyr and Pro. This intramolecular hydrogen bond may be responsible for the high potency of endomorphin-2, as well as its conformational stability.</p>

<p>Please enquire for more information about (Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt 9)-LHRH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro-OH is a peptide that is derived from the sequence of fibronectin. It has been shown to be taken up by urchin cells, which are spherical and have a toroidal shape. This peptide also has modular properties and forms a particle with a pegylated molecule. The amino acid sequence of this peptide is unmodified. H-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys Pro -OH is a synthetic ligand that can be used in the ligation of mesenchyme cells.</p>

<p>Please enquire for more information about PAR-3 (1-6) amide (mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Gly-Pro-Pro-OH trifluoroacetate salt is an amide with a high specificity and low energy. This compound is activated by sequences of collagen, which may be due to its ability to hydrate intracellular calcium concentrations. H-Gly-Pro-Pro-OH trifluoroacetate salt has been shown to have polymerase chain activation activity in the presence of lysine residues, and it can bind to regulatory sites on DNA. H-Gly-Pro-Pro-OH trifluoroacetate salt has also been shown to have hydroxyproline hydroxylase activity, which leads to a helical structure.</p>

<p>Please enquire for more information about H-Ile-2-chlorotrityl resin (200-400 mesh) (Low Substitution) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>