Acides aminés (AA)

D-Pen 2,p-chloro-Phe4,D-Pen 5)-Enkephalin H-Tyr-D-Pen-Gly-p-chloro-Phe-D-Pen (Disulfide bond) is a peptide that belongs to the family of opioid drugs. It has low potency and is used in pharmacological studies as a nonselective antagonist of δ-, μ-, and κ-(kappa) receptors. This drug blocks pain by binding to the same receptor sites that are activated by endogenous opioids and has been shown to be effective against both inflammatory and neuropathic pain. DPDPE has also been shown to have a high safety profile with minimal side effects.

Please enquire for more information about Boc-Gly-Merrifield resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Z-L-Thr-OH is a synthetic peptide that contains the amino acid sequence of l-threonine. It is an amide with a carbamic acid and chloride functional group. The monomers are linked by ring-opening reactions, which are sequences of reactions in which the bond between two adjacent carbon atoms is broken and then immediately formed again with the addition of another molecule. Z-L-Thr-OH has been shown to hydrolyze leukocytes and inhibit bacterial growth in vitro. In vivo studies have also shown that Z-L-Thr-OH inhibits neutrophil recruitment, degranulation, and oxidative burst in response to chemoattractants or bacteria. This peptide has also been shown to be effective against methicillin resistant Staphylococcus aureus (MRSA) and other clinically significant pathogens.

Acetyl-Pepstatin is a protein data inhibitor that binds to the active site of enzymes, inhibiting their function. Acetyl-pepstatin has been shown to inhibit cathepsin D, chymotrypsin, and trypsin. It also inhibits the activity of proteases in the stomach and intestinal tract. Acetyl-Pepstatin is used as an anti-inflammatory drug for the treatment of chronic obstructive pulmonary disease (COPD) and congestive heart failure (CHF). The inhibition of these enzymes reduces inflammation by preventing the activation of inflammatory cytokines. It also prevents collagen from being degraded by proteases, which leads to decreased degradation of cartilage by chondrocytes. This drug's mechanism is similar to that of acetylsalicylic acid (aspirin), in that it inhibits prostaglandin synthesis.br>

FA-Ala-Lys-OH is a lysine derivative with a molecular weight of 243.2 daltons and a pKa of 6.5. It has been shown to be biologically active in humans and animals, and can be used as an amino acid supplement for patients with liver disease or kidney failure who require dialysis. FA-Ala-Lys-OH binds to the creatine kinase receptor on the surface of cells and causes cell lysis, which may be due to its ability to bind to the enzyme's allosteric site. This compound also has anti-viral properties, inhibiting the growth of recombinant virus mcf-7 in vitro by binding to erythrocyte membranes and disrupting protein synthesis. The 6-Fluoro-3-indoxyl beta D galactopyranoside is an antituberculosis drugs that belongs to the class of rifamycins. Rifapentine inhibits bacterial

Please enquire for more information about H-Arg-Tyr-NH2·2 HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page

Ac-Met-AMC is a nucleoside analog that is an active inhibitor of the enzyme DNA polymerase. This drug has been shown to be effective in preventing the growth of cancer cells in tissue cultures, and it has also been used to study the relationship between isoforms and oxygenated species. Ac-Met-AMC binds to the cytosolic side of the enzyme, which reduces its activity, but this binding does not affect the enzyme's ability to bind substrate or ATP. Ac-Met-AMC has been shown to hydrolyze with a rate constant of 6 x 10 M(-1) s(-1).

H-Tyr-His-OH is a trifluoroacetic acid derivative that is a histidine odorant. It can be used as a substitute for histidine in the detection of blood pressure, due to its ability to bind to nitric oxide and histidine receptors. H-Tyr-His-OH has been shown to have immunological properties, and it has been used as an immunogen in the production of monoclonal antibodies against human erythrocytes. H-Tyr-His-OH is also considered to be a potential biomarker because it can be detected by LC-MS/MS methods.

Please enquire for more information about Farnesyl-Met-OMe including the price, delivery time and more detailed product information at the technical inquiry form on this page

H-Phe-Gly-Gly-OH is a phosphatase enzyme inhibitor that acts as a competitive inhibitor of serine/threonine phosphatases. It has been shown to inhibit the activity of protein data, which are enzymes that catalyze the hydrolysis of phosphate groups from proteins. This inhibition of protein data leads to an increase in the levels of protein kinase A (PKA) and cyclic AMP (cAMP) in human serum. H-Phe-Gly-Gly-OH also inhibits an enzyme called phospholipase A2, which is responsible for fatty acid metabolism, leading to an accumulation of fatty acids in cells. It has been shown that H-Phe-Gly-Gly-OH has anticancer activity against meningioma and squamous carcinoma cells in humans.

Cyclosporine is a cyclic peptide that is used as an immunosuppressive drug. It binds to the cytosolic protein phosphatase, preventing its activation. Cyclosporine also binds to other proteins in the cell, such as casein kinase II and cyclophilin, leading to changes in cellular function. It has been shown to inhibit the production of cytokines and other inflammatory mediators by inhibiting tyrosine kinase activity. Cyclosporine is metabolized into FK506, which has a similar structure but greater potency than cyclosporine. The mechanism of action for FK506 is not fully understood but it appears to be related to its ability to bind to tyrosine kinases and inhibit their activity.

Please enquire for more information about H-Lys-Thr-Tyr-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Boc-D-Ala-PAM resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about H-Glu-Gly-Arg-pNA acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Ac-muramyl-D-Ala-D-Glu-NH2 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about H-Asp(His-OH)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Boc-D-Glu-OEt·DCHA including the price, delivery time and more detailed product information at the technical inquiry form on this page

H-Pro-Ser-Hyp-Gly-Asp-Trp-OH is a cyclic hexapeptide with a high activity against platelets. It is an antagonist of the cyclic RGD sequence, which is present in fibrinogen, fibronectin, vitronectin and other proteins. This peptide binds to the n-terminal residue of these proteins and prevents them from binding to their receptors on the surface of platelets. H-Pro-Ser-Hyp-Gly-Asp-Trp-OH has been shown to be specific for human platelets and does not bind to erythrocytes or leukocytes.

N-Tritylglycine is an acidic amino acid that can be protonated in a highly acidic environment. It has been shown to inhibit the growth of tumor tissue by inducing apoptosis and inhibiting protein synthesis. N-Tritylglycine is used as a reagent for analytical chemistry, where it is used to detect amines such as histamine and serotonin. N-Tritylglycine also has been shown to be potent inhibitor of kinesin.

Please enquire for more information about Neuropeptide VF (56-92) (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Ac-Ser-Asp-Lys-Pro-OH is a tetrapeptide that has been shown to stimulate the growth of cells in vitro. It has been found to inhibit the production of interleukin-1β and tumor necrosis factor α, which are cytokines that are involved in inflammation. Ac-Ser-Asp-Lys-Pro-OH stimulates the production of growth factor β1 and collagen, which may be due to its ability to bind to toll like receptor 4 (TLR4). Acetylserotonin has been shown to have antiinflammatory and antifibrotic properties in animal models. Acetylserotonin also inhibits cancer cell growth and reduces drug resistance.

4-Iodo-1-methyl-1H-imidazole is a trifluoroethylamine that inhibits the activity of tyrosine kinases. It binds to the active site of tyrosine kinase and prevents the binding of ATP, preventing phosphorylation and activation of downstream substrates. 4-Iodo-1-methyl-1H-imidazole has been shown to inhibit the proliferation of tumor xenografts in mice, as well as inhibiting headgroup binding and cellular proliferation in vitro. This agent also has a nanomolar range and high selectivity for protein kinases, which may make it suitable for therapeutic purposes.

Please enquire for more information about 5-Fmoc-amino-10,11-dihydro-5H-dibenzo[a,d]-cycloheptenyl-2-oxyacetyl-DL-Nle-4- methyl-benzhydrylamide resin including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Boc-Thr-OBzl including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about H-Ala-Ala-Ala-Tyr-Ala-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page

Neuropeptide EI is a cyclic peptide that has been shown to have receptor activity in the caudate putamen, as well as locomotor activity and metabolic rate. Neuropeptide EI has also been shown to inhibit lymphatic vessels and amide sequences in fat cells. It has been shown to have various biological functions, such as an anti-inflammatory agent, an analgesic, and a chemotherapeutic agent. It is active against cancer cells and autoimmune diseases, but is inactive against bacteria.

Please enquire for more information about H-Ala-2-chlorotrityl resin (200-400 mesh) (Low Substitution) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Bz-Ile-Glu-Gly-Arg-pNA acetate salt is an anticoagulant that binds to heparin. It has been shown to inhibit protease activity in soybean trypsin by binding to the active site of the enzyme. Bz-Ile-Glu-Gly-Arg-pNA acetate salt has also been shown to have a molecular weight of heparin and a protein synthesis inhibition rate of fibrinogen, which is responsible for coagulation.

Pyr-Gly-OH is a metabolite of the amino acid glutamate. It has been shown that this metabolite is formed by a non-enzymatic dehydration of glutamate. This compound has been shown to be effective in treating bowel disease and cancer, as well as stimulating the production of fibrinogen in the blood. Pyr-Gly-OH has also been found to have anti-inflammatory effects and an increased effect on glutamic receptors.

Please enquire for more information about H-Asp(OtBu)-2-chlorotrityl resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Z-Phe-Leu-Ala-OH is a homologous protein that has been shown to have proteolytic activity. It has a neutral pH and is stable in the presence of metal ions. This enzyme is structurally similar to subtilisin, with a sequence of residues containing two histidine residues, which are important for stability. The kinetic parameters of this enzyme were determined by analyzing its activity under different conditions and at different temperatures. The mutant Z-Phe-Leu-Ala-OH was found to be more active than the wild type at high temperature, but less active at low temperature, suggesting that the protein could be used as an industrial catalyst in food processing or chemical production.

Please enquire for more information about DABCYL-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675)-EDANS ammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Z-Asp-Gln-Met-Asp-AFC including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about HSV-1 Glycoprotein (gB) (497-507) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Z-Arg-AMC hydrochloride salt is a proteolytic agent that inhibits serine proteases. It can be used to study the biological function of proteases and as a tool in the kinetic analysis of protease activity. Z-Arg-AMC hydrochloride salt has been shown to inhibit trypsin, chymotrypsin, and elastase enzymes at nanomolar concentrations. This compound also inhibits human pathogens such as enterovirus 71 and herpes simplex virus type 1, which are associated with severe disease symptoms. The structural analysis of Z-Arg-AMC hydrochloride salt has shown it to be a racemic mixture of L-Arginine and D-Arginine with an average molecular weight of 313.5 Da.

Please enquire for more information about Autocamtide-2-Related Inhibitory Peptide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Ac-Ile-Glu-Pro-Asp-pNA is a synthetic peptide that has been shown to induce apoptosis in tumor cells. The peptide was found to cause cell lysis and necrotic cell death, which is associated with the activation of serine proteases. Ac-Ile-Glu-Pro-Asp-pNA also has been shown to have a toxicity profile similar to other apoptotic agents such as staurosporine, but it has not been tested for its ability to kill cancer cells without causing damage to healthy cells. Ac-Ile-Glu-Pro-Asp-pNA induces mitochondrial membrane depolarization and protein synthesis inhibition in K562 cells, which are human erythroleukemia cells. This peptide also has shown an ability to bind with monoclonal antibodies and inhibit the growth of casein.

Please enquire for more information about Fmoc-Gly-Wang resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page

H-Arg-Ile-OH acetate salt is a regulatory protein that is found in plant cells. It has been shown to be involved in the regulation of cancer, as well as having some anti-inflammatory activities. H-Arg-Ile-OH acetate salt also has been shown to inhibit the production of fatty acids and coagulation factors by inhibiting serine proteases and thromboplastin activity, respectively. H-Arg-Ile-OH acetate salt may have an important role in regulating blood clotting by preventing fibrinogen from converting to fibrin, which leads to clot formation.

Please enquire for more information about Fmoc-D-Leu-Wang resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Z-Ala-Arg-Arg-4MbetaNA acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine including the price, delivery time and more detailed product information at the technical inquiry form on this page

8-Phenyltheophylline (8PT) is an adenosine receptor agonist that is used as a bronchodilator for the treatment of asthma. It has been shown to increase the intracellular calcium concentration in hl-60 cells and in rat papillary muscles. 8PT also has locomotor activating effects, which are thought to be due to its ability to block potassium channels in the hippocampal formation. These effects may be related to ATP-sensitive potassium channels, which have been shown to be sensitive to ATP in untreated mice. 8PT also has anti-arrhythmic properties, which may be due to its ability to inhibit sodium channels and its effect on heart rate and contractility.

Endogenous heptapetide which causes vasodilation and has anti-hypertensive properties.

Bosentan is a potent inhibitor of the uptake of organic anions. It is used in the treatment of pulmonary arterial hypertension and has been shown to be effective against pravastatin-resistant HIV protease inhibitors, such as saquinavir, quinidine, and rosuvastatin. Bosentan inhibits uptake by binding to the transporter protein at a site that does not overlap with the binding site for organic anion substrates. This leads to a change in kinetic parameters for substrates, such as pravastatin and saquinavir. The binding site on bosentan may also be elucidated through monolayer experiments with efflux transporters.

Please enquire for more information about H-Asp-Phe-NH2 trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-[(1-Methylindole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-bezimidazole is a reactive heterocyclic compound. It is a carboxylic acid and an amide with a peptic and cephalalgic effect. The symptoms of 5-[(1-methylindole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-bezimidazole are hemicrania and amnesia. It has been expressed in the calf thymus DNA.

Please enquire for more information about Disodium (1-methyl-4-oxoimidazolidin-2-ylidene)phosphoramidate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Fmoc-2,6-dichloro-L-phenylalanine including the price, delivery time and more detailed product information at the technical inquiry form on this page

(Des-Gly10, tBu-D-Gly6,Pro-NHEt 9)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-tBu-D-Gly-Leu-Arg-Pro-NHEt acetate salt is a synthetic hormone that belongs to the group of gonadotropin releasing hormones (GnRH). It is used in veterinary medicine to stimulate ovulation and follicular growth in animals. (Des-Gly10, tBu-D-Gly6, Pro -NHEt9)-LHRH acetate salt Pyr -His -Trp -Ser -Tyr -tBu -D -Gly -Leu -Arg -Pro NHEt acetate salt is a prodrug that is hydrolyzed in vivo to buserelin, its active form. This drug has been shown to be effective against estradiol benzoate and sodium salts