Acides aminés (AA)

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H-Thr-Arg-OH sulfate salt is a molecule that contains the active amino acid residues of vasoactive intestinal peptide (VIP) and reversed-phase high-performance liquid chromatography. The structure of VIP was determined by stepwise synthesis and chloromethyl ketone activation. It has been shown to have an intestinal effect, which is due to its ability to increase blood pressure. This drug also has potential as a therapeutic agent in the treatment of hypertension, heart disease, or diabetes mellitus.

H-Gly-Gly-Pro-OH is a recombinant polypeptide with affinity for amino acids. It is a positionally defined sequence of amino acids that has been shown to bind to Alzheimer's disease (AD) amyloid peptides and inhibit the formation of beta amyloid fibrils. The N-terminal sequence of this polypeptide is immunogenic, which may be useful for generating antibodies against AD.

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Bz-Arg-OMe carbonate salt is a protease inhibitor that binds to the active site of serine proteases, inhibiting their activity. Bz-Arg-OMe carbonate salt has been shown to have inhibitory effects on Leishmania, a protozoan parasite. It is also an inhibitor of fibrinolysis, which may be due to its ability to bind calcium ions and serum albumin. Bz-Arg-OMe carbonate salt has affinity for carbohydrates and interacts with peptides.

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4-Iodo-1-methyl-1H-imidazole is a trifluoroethylamine that inhibits the activity of tyrosine kinases. It binds to the active site of tyrosine kinase and prevents the binding of ATP, preventing phosphorylation and activation of downstream substrates. 4-Iodo-1-methyl-1H-imidazole has been shown to inhibit the proliferation of tumor xenografts in mice, as well as inhibiting headgroup binding and cellular proliferation in vitro. This agent also has a nanomolar range and high selectivity for protein kinases, which may make it suitable for therapeutic purposes.

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Ac-Thr-Ile-Nle-psi(CH2NH) Nle-Gln-Arg-NH2 is a protease inhibitor that prevents the breakdown of proteins by inhibiting the activity of proteases. It binds to the active site of these enzymes and blocks the access of other substrates. Ac-Thr-Ile-Nle-psi(CH2NH) Nle-Gln-Arg-NH2 has been shown to bind to a number of proteases, including serine, cysteine, aspartic acid, and metalloendoproteases. It inhibits the hydrolysis of peptide bonds in proteins by binding to the active site and blocking access to other substrates. The chemical structure is hydrophobic due to presence of a hydroxy group that can interact with hydrophobic regions on proteins. Acetylation at position Thr1 is important for its inhibitory activity against certain proteases such as

Alternariol-9-methyl ether is a natural compound that has been shown to have significant cytotoxic effects on murine hepatoma cells. This compound also synergizes with anti-retroviral drugs and has been found to be capable of inducing apoptosis in HIV-infected T cells at low concentrations. Alternariol-9-methyl ether is structurally related to the polycyclic aromatic hydrocarbons, such as alternariol, which are only weakly toxic to mice but are potent pro-apoptotic proteins when bound covalently to DNA. Structural analysis of this compound revealed that it inhibits the binding of a pro-apoptotic protein (Bid) to its target site on dsDNA, preventing Bid from initiating apoptosis. It is thought that this effect may be responsible for its synergistic interaction with active antiretroviral therapy.

H-Val-Asn-OH is a polyhydroxyamine that is soluble in water and has a low freezing point. It can be used as a coating material, sectioning medium, or to study the thermal expansion of materials. H-Val-Asn-OH has been shown to have no significant effect on the growth rate of bacteria and spores. H-Val-Asn-OH is made up of nitrogen atoms, ferrite, and strain. The microstructure of H-Val-Asn-OH includes a phase equilibrium with ferrite and strain morphology.

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Pyr-Gly-OH is a metabolite of the amino acid glutamate. It has been shown that this metabolite is formed by a non-enzymatic dehydration of glutamate. This compound has been shown to be effective in treating bowel disease and cancer, as well as stimulating the production of fibrinogen in the blood. Pyr-Gly-OH has also been found to have anti-inflammatory effects and an increased effect on glutamic receptors.

H-Met-Gly-Gly-OH is a tripeptide that has been synthesized and is used in microassays to measure the activity of methionine aminopeptidase. This enzyme hydrolyzes peptides with N-terminal amino acids such as methionine, which are derived from proteins. The activity of methionine aminopeptidase can be determined by measuring the release of H2O2, which is proportional to the concentration of peptides in the sample. The assay measures the change in absorbance at 340 nm on a spectrophotometer as a result of H2O2 production.

H-Gly-Gly-His-OH is a molecule that is found in human serum. It is a ligand with coordination properties and has been shown to bind to copper. H-Gly-Gly-His-OH has been studied spectroscopically in the presence of human serum albumin, and it has been observed that the protonation state and interaction of this molecule are dependent on the speciation and concentration of copper.

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4-Methoxy-3-(trifluoromethyl)benzoic acid is a useful scaffold that can be used as a building block for the synthesis of complex compounds. It has been shown to react with various reagents and is a versatile building block that can be used in organic synthesis. 4-Methoxy-3-(trifluoromethyl)benzoic acid is a high quality chemical and has been classified as speciality chemicals. This product is also known by the CAS number 213598-09-5.

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PHM-27 is a human protein that contains a c-terminal histidine and n-terminal lysine. It contains an amino acid composition of histidine, valine, alanine, aspartic acid, glycine, serine, threonine, arginine, and methionine. PHM-27 is present in the cardiovascular system, nervous system, gastrointestinal system, and respiratory system. It has been shown to be involved in the synthesis of peptides important for blood clotting.

Urinary Trypsin Inhibitor Fragment H-Arg-Gly-Pro-Cys-Arg-Ala-Phe-Ile-OH is a synthetic peptide that is used as a diagnostic agent. It has been shown to inhibit proinflammatory cytokines in vitro and in vivo. This peptide binds to the amino acid sequences of phospholipase A2, which are found in tumor cells, and can be used for cancer diagnosis. Urinary Trypsin Inhibitor Fragment H-Arg-Gly-Pro-Cys-Arg-Ala-Phe-Ile-OH also binds to DNA methylation, which may be useful for studying DNA methylation patterns in cancer cells.

Acetylation is the process of reacting an organic compound with acetic acid to produce an ester and water. Acetylation is one of the most common reactions in organic chemistry. Acetylating agents, such as acetic anhydride or acetyl chloride, are often used in chemical synthesis because they react selectively with primary and secondary alcohols to form esters. The acetylation reaction can be used to modify proteins by attaching an acetyl group to the amine group of a lysine residue. This modification prevents the protein from binding to other proteins and can alter its function. Acetylation also has been implicated in several diseases, such as hepatitis and inflammatory bowel disease.

H-Asp-Arg-Gly-Asp-Ser-OH is an amide with a molecular weight of 456.5 and a purity of 99.2%. This compound has been shown to inhibit tumor cell growth in vitro and in vivo, as well as the metastasis of tumor cells. H-Asp-Arg-Gly-Asp-Ser-OH is also capable of inhibiting tumor cells that are resistant to conventional anti cancer drugs such as 5FU, cisplatin, and doxorubicin.

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Ne-Fmoc-L-lysine is an amine with a homopolypeptide backbone. It is insoluble in water and has a low profile. Ne-Fmoc-L-lysine is synthesized using solid phase chemistry, which can be used for the synthesis of nanocarriers. It has been shown to interact with other molecules such as polymers and proteins. Ne-Fmoc-L-lysine can also be used in supramolecular architectures and oriented microscopy techniques.

H-Val-Tyr-Val-OH is a water soluble polymer that has a sulfamic acid group and a hydroxyl group. The polymer film is used as an additive for cellulose acetate, which is used in the manufacture of films, lacquers, and adhesives. H-Val-Tyr-Val-OH increases the solubility of the cellulose acetate in hydrochloric acid and reduces its tendency to dissolve in water. H-Val-Tyr-Val-OH also has a high degree of uv absorption. Constant techniques are used for analytical chemistry, such as gas chromatography and nuclear magnetic resonance spectroscopy, to study the surface properties of micelles formed from H-Val-Tyr-Val-OH.

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H-Pro-His-Phe-OH is a proteolytic enzyme that belongs to the group of serine proteases. It is a member of the subtilisin family and has been used in research for its ability to cleave proteins at random. H-Pro-His-Phe-OH has been shown to hydrolyze lactococcal proteinase and other serine proteases, such as trypsin, chymotrypsin, and elastase.

Neuropeptide EI is a cyclic peptide that has been shown to have receptor activity in the caudate putamen, as well as locomotor activity and metabolic rate. Neuropeptide EI has also been shown to inhibit lymphatic vessels and amide sequences in fat cells. It has been shown to have various biological functions, such as an anti-inflammatory agent, an analgesic, and a chemotherapeutic agent. It is active against cancer cells and autoimmune diseases, but is inactive against bacteria.

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H-Tyr-Phe-OH is a peptide that is derived from the amino acid sequence of human epidermal growth factor and has been shown to inhibit HIV infection in vitro. H-Tyr-Phe-OH binds to the dna binding site on the protein gp120, which is essential for viral binding to cells and subsequent infection. The peptide has also been shown to bind to serum aminotransferase levels and produce an antibody response in humans. This peptide has biological properties that may be useful for treatment of many infectious diseases, such as hepatitis and HIV infection.

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H-Gly-Gly-Glu-OH is a hydrolysate of the proteasome peptide. It has reversed-phase and liquid chromatography properties, which make it a useful biochemical tool for the analysis of proteins. The carboxylate group at the end of H-Gly-Gly-Glu-OH can be used as an isopeptide to determine the sequence of peptides that are synthesized by a prokaryotic or eukaryotic cell. H-Gly-Gly-Glu-OH can also be used to cleave ligation products in order to analyse them.

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(2R,3S)-3-Amino-2-hydroxy-3-phenylpropanoic acid hydrochloride is an organic compound that is used in the manufacture of taxol, an anticancer drug. It is synthesized by reacting chloroacetic acid with a metal hydroxide, such as sodium hydroxide or potassium hydroxide. The reaction proceeds spontaneously to form the enantiomerically pure (2R,3S) form and unreacted (2S,3R) form. The (2R,3S) enantiomer has been found to be more reactive than the (2S,3R) form. Quaternary ammonium salts are formed when the (2R,3S) enantiomer reacts with quaternary ammonium compounds such as benzyltrimethylammonium chloride. This compound can also be used in catalytic reactions to produce drugs such as carbapenems and pen

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8-Phenyltheophylline (8PT) is an adenosine receptor agonist that is used as a bronchodilator for the treatment of asthma. It has been shown to increase the intracellular calcium concentration in hl-60 cells and in rat papillary muscles. 8PT also has locomotor activating effects, which are thought to be due to its ability to block potassium channels in the hippocampal formation. These effects may be related to ATP-sensitive potassium channels, which have been shown to be sensitive to ATP in untreated mice. 8PT also has anti-arrhythmic properties, which may be due to its ability to inhibit sodium channels and its effect on heart rate and contractility.

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Endogenous heptapetide which causes vasodilation and has anti-hypertensive properties.

Bosentan is a potent inhibitor of the uptake of organic anions. It is used in the treatment of pulmonary arterial hypertension and has been shown to be effective against pravastatin-resistant HIV protease inhibitors, such as saquinavir, quinidine, and rosuvastatin. Bosentan inhibits uptake by binding to the transporter protein at a site that does not overlap with the binding site for organic anion substrates. This leads to a change in kinetic parameters for substrates, such as pravastatin and saquinavir. The binding site on bosentan may also be elucidated through monolayer experiments with efflux transporters.

5-[(1-Methylindole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-bezimidazole is a reactive heterocyclic compound. It is a carboxylic acid and an amide with a peptic and cephalalgic effect. The symptoms of 5-[(1-methylindole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-bezimidazole are hemicrania and amnesia. It has been expressed in the calf thymus DNA.

(Des-Gly10, tBu-D-Gly6,Pro-NHEt 9)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-tBu-D-Gly-Leu-Arg-Pro-NHEt acetate salt is a synthetic hormone that belongs to the group of gonadotropin releasing hormones (GnRH). It is used in veterinary medicine to stimulate ovulation and follicular growth in animals. (Des-Gly10, tBu-D-Gly6, Pro -NHEt9)-LHRH acetate salt Pyr -His -Trp -Ser -Tyr -tBu -D -Gly -Leu -Arg -Pro NHEt acetate salt is a prodrug that is hydrolyzed in vivo to buserelin, its active form. This drug has been shown to be effective against estradiol benzoate and sodium salts

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