Acides aminés (AA)

Stability Hygroscopic
Applications L-Saccharopine is a product of breakdown of essential amino acid Lysine (L468895). Saccharopine is also part of the α-aminoadipate pathway of fungal lysine biosynthesis.
References Higashino, K., et al.: Biochem. Biophys. Res. Commun., 20, 285 (1965); Johansson, E., et al.: Structure, 8, 1037 (2000)

Applications Labelled analogue of L-Phenylalanine, an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded amino acids, which in turn is converted to L-DOPA and further converted into dopamine, norepinephrine, and epinephrine. L-Phenylalanine is produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.
References Hollunger, G. et al.: Acta Pharmacol. Toxicol., 34, 391 (1974); Bagchi, S.P. et al.: Biochem. Pharmacol., 26, 900 (1977);

Applications 3-Methyl-1,3-butanediol is a useful compound in carbon oxygen coupling reactions.

Applications cis-Propenylphosphonic Acid (R)-(+)-α-Methylbenzylamine Salt is used as a reagent in the microbial production of Fosfomycin (F727505); a compound used as an antibiotic in the treatment of urinary tract infections.
References Watanabe, M., et al.: Appl. Environ. Microb., 65, 1036 (1999); Itoh, N., et al.: Appl. Microbiol. Biot., 43, 394 (1995); White, R.F., et al.: Appl. Microbiol., 22, 55 (1971); Keating, G. et al.: Drugs, 73, 1951 (2013); Demir, T. et al.: Int. J. Infect. Dis., 17, e966 (2013)

Applications DMTMM, a conjugating agent that efficiently conjugat PnPS to Luminex microspheres without affecting the antigenicity of a broad set of PnPS.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wrzesien, J. & Graham, D.: Tetrahedron, 68, 1230 (2012); Schlottmann, S. et al.: J. Im. Meth., 309, 75 (2006)

Applications 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid (cas# 144059-86-9) is a useful research chemical.

Applications 5-Methoxy-2-methylaniline (cas# 50868-72-9) is a useful research chemical.

Applications L-Thioproline is used to create a monolayer on gold electrodes for the determination Copper(II). L-Thioproline has shown to be an effect inhibitor of proline absorption in Saccharomyces chevalieri.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cui, X., et. al.: Sci. China Chem., 53, 257 (2010); Magana-Schwenchke, N., Schwencke, J.: BBA-Biomembranes, 173, 313 (1969)

Applications Deuterated Repaglinide, a non-sulfonylurea oral hypoglycemic agent which is used as an antidiabetic.
References Wolffenbuttel, B.H.R., et al.: Eur. J. Clin. Pharmacol., 45, 113 (1993), Ampudia-Blasco, F.J., et al.: Diabetologia, 37, 703 (1994),

Applications This compound contains up to 25% of the two other regioisiomers.

Applications H-ALA-ALA-ALA-ALA-ALA-OH (cas# 10183-34-3) is a useful research chemical.

Applications Fmoc-L-cysteic acid (cas# 751470-47-0) is a useful research chemical for organic synthesis and other chemical processes.
References Dialer, L. O., et al.: J. Med. Chem., 56, 7552 (2013); Revell, J. D., et al.: Tetrahedron, 63, 8420, (2007)

Stability Light Sensitive
Applications 4-Methoxyphenylhydrazine hydrochloride was used in the preparation of 5-cyano-3-(5-methoxy-2-methylindol-3-yl)-1,2,4-thiadiazole. It was also used to synthesize diarylpyrazoles as possible cyclooxygenase 2 ((COX-2)) inhibitors.
References Iwakawa, T., et al.: Chem. Pharm. Bull., 48, 160 (2000); Penning, T., et al.: J. Med. Chem., 40, 1347 (1997)

Applications L-Methionine Sulfoxide 13C1 is a labelled analogue of L-Methionine Sulfoxide ( M260450). L-Methionine Sulfoxide ( M260450) an intermediate in the synthesis of the acyclic amino carboxylic acid L-Methionine sulfoximine.
References Lee, B., et al.: J. Biol. Chem., 283, 28361 (2008), Nordqvist, A., et al.: Bioorg. Med. Chem., 16, 5501 (2008);Balog, E., et al.: Biochem., 48, 3005 (2009);

Applications An acylglycine present in urniary excretion that can be analyzed and be used as diagnostic tool for metabolic disorders, complementary to organic acids and acylcarnitine profiles.
References Bonafe, L. et al.: Mol. Genetics Metab., 69, 302 (2000);

Applications Labelled 4-Methyl-2-oxovaleric Acid, an α-ketomonocarboxylic acid that triggers insulin release by acting upon receptor sites which differ from those occupied by amino acids. 4-Methyl-2-oxovaleric Acid is an intermediate in the metabolism of Leucine.
References Panten, U. et al.: Naun.-Schmied. Arch. Pharmacol., 291, 405 (1975); Vague, P. et al.: Diab. Metab., 1, 185 (1975); Francois, G. et al.: Lancet, 1, 858 (1984);

Applications (3-Methyl-2-butenyl)triphenyl-phosphonium Bromide (cas# 1530-34-3 ) is a compound useful in organic synthesis.

Applications Intermediate for the preparation of Naratriptan and other indole sulfonamide derivatives.

Stability Hygroscopic
Applications A labelled metabolite of Acrylonitrile (ACN).
References Guengerich, F., et al.: Cancer Res., 41, 4925 (1981), Leonard, A., et al.: Mutation Res., 436, 263 (1999), Stadler, R., et al.: J. Agric. Food Chem., 52, 5550 (2004), Dybing, E., et al.: Food Chem. Toxicol., 43, 365 (2005), Rice, J., et al.: Mutation Res., 580, 3 (2005),

Applications Cyclic propano guanine adduct DNA acetaldehyde histone.
References Nath, R., et al.: Cancer Res., 58, 581 (1998), Wang, M., et al.: Chem. Res., 13, 1065 (2000), Terashima, I., et al.: Biochemistry, 40, 4106 (2001), Yokoyama, A., et al.: Carcinogenesis, 23, 1851 (2002),

Applications Isoleucine-d10 (mixture of diastereomers) (CAS# 29909-02-2) is a useful isotopically labeled research compound and can be used in gas liquid chromatography.
References VandenHeuvel, W., et.al., J. Chromatogr., 50, 405-412, (1970);

Applications Tris(2-(2-methoxyethoxy)ethyl)amine (cas# 70384-51-9) is a useful research chemical.

Applications 4-(1-Methylethyl)benzoic Acid is used in the synthesis of quinuclidine benzamides as agonists for nicotinic acetylcholine receptors. Also used in the synthesis of nifuroxazide analogues showing antimicrobial activity against methicillin-resistant Staphylococcus.
References Bodnar, A. et al.: J. Med. Chem., 48, 905 (2005); Masunari, A. et al.: Bioorg. Med. Chem. Lett., 15, 4229 (2007);

Applications Protected (S) enantiomer of the amino acid Phenylalanine.
References Zhu, P., et al.: Bioorg. Med. Chem. Lett., 19, 6966 (2009), Cramer, B., et al.: Bioorg. Med. Chem., 18, 343 (2010),

Applications Pipecolic acid is involved in synaptic transmission in the central nervous system. The l-form occurs in plants.
References Nomura Y., et al.: Neurochem. Res., 6, 391 (1981),

Applications 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine is an intermediate used to prepare nonracemic γ-bicyclic heteroarylpiperazine- and heteroarylpiperidine-substituted prolinylthiazolidines as selective and orally active dipeptidylpeptidase 4 inhibitors for use as antidiabetic agents.
References Yoshida, T., et al.: Bioorg. Med. Chem., 20, 5705 (2012)

Impurity Repaglinide EP Impurity C/ Repaglinide USP Related Compound A
Applications Repaglinide EP Impurity C

Applications 3-Hydroxy-4-methylaniline

Applications N-ACETYLISOLEUCINE (cas# 3077-46-1) is a useful research chemical.

Applications Fmoc-n-me-lys(boc)-oh