Fmoc-Asp-allyl ester

CAS : 144120-53-6

Ref. 01-4019715

Informations sur le produit

• Nom: Fmoc-Asp-allyl ester
• Synonymes: Fmoc-Asp-OAll, (3S)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxo-4-(prop-2-en-1-yloxy)butanoic acid (non-preferred name), (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxo-4-(prop-2-en-1-yloxy)butanoic acid (non-preferred name)
• CAS: 144120-53-6

Description

a-Allyl esters are useful tools for the on-resin head-to-tail cyclization of peptides and for the synthesis of side-chain lactam peptides, glyco- and sulfo-peptides, and branched peptides. Allyl esters are cleaved under mild conditions using Pd(0). These conditions are compatible with Fmoc- and Boc-SPPS. The Asp a-Allyl esters show a somewhat higher propensity for base-catalyzed aspartimide formation than the corresponding b-esters. Fmoc-Asp-OAll is a versatile educt for synthesizing complex Asp and Asn derivatives, e.g., N-glycosylated Asn building blocks.

• Marque: Bachem

Propriétés chimiques

• Masse moléculaire: 395.41
• Formule: C₂₂H₂₁NO₆
• Degré de pureté: 99.3%
• Couleur/Forme: White Powder