Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂

CAS : 140430-53-1

Ref. 01-4026036

Informations sur le produit

• Nom: Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂
• Synonymes: 7-Methoxycoumarin-4-Acetyl-Pro-Leu-Gly-Leu-Dnp-(2,3-Diaminopropionyl)-Ala-Arg, amide, Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2
• CAS: 140430-53-1

Description

Mca-PLGL-Dpa-AR-amide is a very sensitive FRET substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. Cleavage at the Gly-Leu bond separates the highly fluorescent Mca group from the efficient 2,4-dinitrophenyl quencher, resulting in an increase in fluorescence intensity. The kcat/Km values for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7·105 and 6.3·105 M-1s-1, respectively.

• Marque: Bachem

Propriétés chimiques

• Masse moléculaire: 1093.16
• Formule: C₄₉H₆₈N₁₄O₁₅
• Degré de pureté: 98.7%
• Couleur/Forme: Yellow Powder