Cyclo(-Arg-Gly-Asp-D-Phe-Val)

CAS : 137813-35-5

Ref. 01-4026200

Informations sur le produit

• Nom: Cyclo(-Arg-Gly-Asp-D-Phe-Val)
• Synonymes: c(RGDfV), Cyclo(Rgdd-Fv), Rgdfv Peptide, Cyclic

Description

c(RGDfV) is a potent inhibitor of cell adhesion. It inhibited tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations in rats provided the first evidence of its utility in the amelioration of ischemic acute renal failure. c(RGDfV) inhibited tubular obstruction by preventing cell-cell adhesion. Hammes et al. showed that the cyclopeptide can also be used to prevent retinal neovascularization. c(RGDfV) binds to αvβ3 receptors.

• Marque: Bachem

Propriétés chimiques

• Masse moléculaire: 574.64
• Formule: C₂₆H₃₈N₈O₇
• Degré de pureté: 96.9%
• Couleur/Forme: White Lyophilisate