GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat)

CAS : 161748-29-4

Ref. 01-4027697

Informations sur le produit

• Nom: GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat)
• Synonymes: Preproglucagon (100-127) amide (human, bovine, guinea pig, mouse, porcine, rat)
• Marque: Bachem
• Description: Glucagon-like peptide-1 (GLP-1) is efficiently degraded by the enzyme dipeptidyl peptidase IV (DPP IV), yielding the major metabolite GLP-1 (9-36) amide. GLP-1 (9-36) amide does not affect glucose disposal in mice either in the presence or absence of intact GLP-1 receptors or in the presence or absence of stimulated insulin levels. This suggests that the GLP-1 metabolite is not involved in the regulation of glucose homeostasis. Elahi et al. have shown that this GLP-1 metabolite acts as a weak insulinotropic agent and inhibits hepatic glucose production.

Propriétés chimiques

• Masse moléculaire: 3089.46
• Formule: C₁₄₀H₂₁₄N₃₆O₄₃
• Degré de pureté: ≥ 98%
• Couleur/Forme: White Powder