Proadrenomedullin (1-20) (human)

CAS : 150238-87-2

Ref. 01-4034490

Informations sur le produit

• Nom: Proadrenomedullin (1-20) (human)
• Synonymes: PAMP, H-Ala-Arg-Leu-Asp-Val-Ala-Ala-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-Nh2, Arldvaaefrkkwnkwalsr-Nh2, Arldvasefrkkwnkwalsr-Nh2, Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-Nh2, Pamp, Pamp (1-20) Human, Pamp Fragment 1-20 Human

Description

Proadrenomedullin, the precursor of adrenomedullin, contains a unique 20-residue sequence termed proadrenomedullin NH₂-terminal 20 peptide (PAMP). The i.v. administration of PAMP produces a rapid and strong hypotensive effect in anesthetized rats. It has been suggested, that PAMP functions as an inhibitory modulator of renal noradrenergic neurotransmission and plays an important role in regulating renal functions. Furthermore, it has been suggested that PAMP can act as an inhibitory regulator of adrenal catecholamine release in vivo and has a potent hyperglycemic effect after intra-third cerebroventricular administration in fasted mice.

• Marque: Bachem

Propriétés chimiques

• Masse moléculaire: 2460.87
• Formule: C₁₁₂H₁₇₈N₃₆O₂₇
• Degré de pureté: 97.2%
• Couleur/Forme: Whitish