Fmoc-Asp(OtBu)-(Hmb)Gly-OH

CAS : 502640-94-0

Ref. 01-4035481

Informations sur le produit

• Nom: Fmoc-Asp(OtBu)-(Hmb)Gly-OH
• Synonymes: Fmoc-Asp(OtBu)-N-(2-hydroxy-4-methoxy-Bzl)-Gly-OH, Fmoc-Asp(Otbu)-(Hmb)Gly-Oh, Fmoc-Asp(Otbu)-N-(2-Hydroxy-4-Methoxy-Bzl)-Gly-Oh, Fmoc-Asp(OtBu)-N(Hmb)-Gly-OH
• CAS: 502640-94-0

Description

Aspartimide formation of the highly base-labile Asp-Gly motif during Fmoc-SPPS may be completely suppressed by coupling this Hmb-protected dipeptide derivative. Additionally, Hmb prevents aggregation of the growing peptide chain as efficiently as the incorporation of a pseudoproline moiety. O-Acylation renders the Hmb moiety acid-stable facilitating the purification of peptides prone to form aggregates. The acyl group can be removed with hydrazine hydrate in DMF (cf. Quibell).

• Marque: Bachem

Propriétés chimiques

• Masse moléculaire: 604.67
• Formule: C₃₃H₃₆N₂O₉
• Degré de pureté: 99.6%
• Couleur/Forme: White