GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat)

CAS : 87805-34-3

Ref. 01-4037542

Informations sur le produit

• Nom: GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat)
• Synonymes: Proglucagon (72-108) (human, bovine, guinea pig, mouse, rat)
• Marque: Bachem
• Description: Glucagon-Like Peptide 1 (GLP-1) is synthesized by posttranslational processing of proglucagon in the intestine and pancreas and plays an important role in metabolic homeostasis. Among the different molecular forms, such as GLP-1 (7-36) amide and GLP-1 (7-37), the function of GLP-1 (1-37) has been unclear. GLP-1 (1-37) was shown to convert intestinal epithelial cells into insulin-producing cells. These observations turned GLP-1 (1-37) into a new promising therapeutic compound for the treatment of diabetes mellitus. In animal models of dilated cardiomyopathy, hypertensive heart failure, and myocardial infarction, GLP-1 has shown a remarkable cardioprotective activity.

Propriétés chimiques

• Masse moléculaire: 4169.54
• Formule: C₁₈₆H₂₇₅N₅₁O₅₉
• Degré de pureté: 97.1%
• Couleur/Forme: White Lyophilisate