Endothelin-1 (human, bovine, dog, mouse, porcine, rat)

CAS : 117399-94-7

Ref. 01-4040254

Informations sur le produit

• Nom: Endothelin-1 (human, bovine, dog, mouse, porcine, rat)
• Synonymes: ET-1 (human, bovine, dog, mouse, porcine, rat), Endothelin 1 human, porcine, H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11), Endothelin 1, Human and Porcine, Endothelin-1,Human
• CAS: 117399-94-7

Description

Endothelin-1, a 21-amino acid peptide from vascular endothelial cells of different mammalian species, is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to ET-1. The role of ET-1 in clinical hypertension has been reviewed by Dhaun et al. and by Sreenivas and Oparil. ET-1 plays a central role in lung fibrosis.

• Marque: Bachem

Propriétés chimiques

• Masse moléculaire: 2491.94
• Formule: C₁₀₉H₁₅₉N₂₅O₃₂S₅
• Degré de pureté: 91.90%
• Couleur/Forme: White