Amiloride hydrochloride dihydrate

CAS : 17440-83-4

Ref. 02-J62168

Informations sur le produit

• Nom: Amiloride hydrochloride dihydrate
• Synonymes: hydrogen amiloride dihydrate chloride, 2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, hydrochloride, hydrate (1:1:2), 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride dihydrate, 3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide dihydrate hydrochloride, 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide hydrochloride (1:1), 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide hydrochloride dihydrate, Amiloride Hcl Dihydrate, Amiloride Hydrochloride (500 Mg), Amiloride Hydrochloride 2-Hydrate, Amiloridehydrochloride,Usp, N-Amidino-3,5-diamino-6-chloropyrazinamide hydrochloride dihydrate, Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride, dihydrate, Pyrazinecarboxamide, N-amidino-3,5-diamino-6-chloro-, monohydrochloride, dihydrate

Description

Amiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 ?M. AmilorideHCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator.This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Marque: Alfa Aesar By Thermo Fisher Scientific

Propriétés chimiques

• Masse moléculaire: 302.12
• Formule: C₆H₁₃Cl₂N₇O₃
• Code InChI: LTKVFMLMEYCWMK-UHFFFAOYSA-N