17-(Allylamino)-17-demethoxygeldanamycin, 99%

CAS : 75747-14-7

Ref. 02-J66960

Informations sur le produit

• Nom: 17-(Allylamino)-17-demethoxygeldanamycin, 99%
• Synonymes: tanespimycin, (4Z,6E,10E)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, (8R,9R,12R,13S,14R,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, (8S,9S,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, 17-(Allylamino)-17-demethoxygeldanamycin, 17-(Allylamino)-17-desmethylgeldanamycin, 17-(Allylamino)geldanamycin, 17-Allylaminodemethoxygeldanamycin, 17-Allylaminogeldanamycin, 17-Demethoxy-17-(2-propenylamino)geldanamycin, 17-Demethoxy-17-allylaminogeldanamycin, 17-N-Allylamino-17-demethoxygeldanamycin, 17Aag, 2-Azabicyclo[16.3.1]docosane, geldanamycin deriv., A 8476, Bms 722782, Cp 127374, Geldanamycin, 17-demethoxy-17-(2-propenylamino)-, Kos 953, NSC 330507, Tanespimycin

Description

17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. In addition to its anti-tumor effects, 17-AAG also induces apoptosis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Marque: Alfa Aesar By Thermo Fisher Scientific

Propriétés chimiques

• Masse moléculaire: 585.70
• Formule: C₃₁H₄₃N₃O₈
• Degré de pureté: 99%
• Couleur/Forme: Red to dark red, Powder
• Code InChI: AYUNIORJHRXIBJ-CQFHKJEWSA-N