Prescribing Medicines for Children

Ref. 12-9780857111357

Informations sur le produit

• Nom: Prescribing Medicines for Children

Description

Edited by Charlotte Barker

1st Edition

Scheduled closure of pharmpress.com

Mark Turner, Mike Sharland

ISBN 9780857111357

Published Jul 2019

Paperback 234 x 156mm

DESCRIPTION:

Your guide to delivering safe and effective medicines for children Prescribing Medicines for Children covers a broad range of important topics in paediatric therapeutics, ranging from the principles of clinical pharmacology in children through to medication safety and drug development. It is an international title that provides guidance on the principles behind optimal neonatal and paediatric prescribing globally. The book is divided into two parts. Part I provides concise educational material relating to paediatric clinical pharmacology and optimising how medicines are developed and prescribed for children. It covers research methods for investigating paediatric medicines, from clinical trials through to pharmacoepidemiology and medicinal formulations. Part II considers key clinical prescribing areas and can be used as a quick reference guide. Each chapter is focused on the key issues in prescribing for a respective clinical specialty or context, with a broad range of subjects from core topics of General Paediatrics through to Paediatric Intensive Care. This book complements British National Formulary for Children (BNFC). Prescribing Medicines for Children is indispensable reference guide for anyone involved in prescribing medicines to neonates and children. This includes undergraduate and postgraduate pharmacists, nurses, paediatricians and primary care physicians, academic scientists, and those working in the pharmaceutical industry and drug regulation.
CONTENTS:

PART I
1 General principles of paediatric clinical pharmacology 1
2 Pharmacokinetics: an overview 7
3 Drug absorption 13
4 Drug distribution: from birth to adolescence 19
5 Drug metabolism 25
6 Drug elimination 31
7 Pharmacodynamics: practical examples 37
8 Pharmacogenetics and pharmacogenomics 43
9 Modelling and simulation: pharmacometrics 49
10 Adverse drug reactions 57
11 Drug interactions 65
12 Pregnancy and lactation 71
13 Paediatric clinical pharmacology 77
14 Education: training programmes and competencies 83
15 The paediatric drug discovery pipeline 91
16 Understanding phase I clinical trials 101
17 Early phase clinical trials: adaptive designs 109
18 Phase IV studies and pharmacovigilance 119
19 Non-interventional studies 123
20 Pharmacoepidemiology 131
21 Innovative strategies in paediatric drug development 137
22 The role of the pharmaceutical industry in developing
medicines for children 149
23 Paediatric drug formulations 157
24 Extemporaneous preparations of medicines for children 163
25 Excipients in medicines for children 171
26 The role of parents and children in paediatric medicines
research 179
27 The ethics of medicines research in children 187
28 Evidence-based prescribing 195
29 Improving training in prescribing 201
30 Electronic prescribing 211
31 Avoiding medication errors 219
32 Intravenous medicines administration 225
33 Team working in medicines administration 233
34 Evidence-based formularies 241
35 Therapeutic drug monitoring 247
36 Medicines for children in low to middle income countries 255
37 Optimal prescribing in the resource-poor setting 265

PART II

38 Gastrointestinal system 273
39 Cardiovascular system 287
40 Respiratory system 297
41 Antiepileptic drug therapy 305
42 Prescribing in infection: anti bacterials 319
43 Prescribing in infection: antifungals and antivirals 339
44 Endocrinology 353
45 Diabetes mellitus 369
46 Adolescent medicine 383
47 Nephrology 391
48 Prescribing blood and blood components 399
49 Oncology: cytotoxic drugs 409
50 Immunosuppressive agents in paediatric solid organ
transplantation 423
51 Nutrition and metabolism 431
52 Rheumatology 443
53 Ophthalmology 455
54 Ear, nose and throat disorders 471
55 Medical therapy in dermatology 481
56 Immunological products 495
57 Prescribing vaccines: an overview 503
58 Sedation and anaesthesia 513
59 Palliative care 523
60 Pain management 535
61 Drugs and pharmacology in paediatric intensive care 547

• Marque: Pharmpress