Amphotericin B

CAS : 1397-89-3

Ref. 3D-AA161113

Informations sur le produit

• Nom: Amphotericin B
• Marque: Biosynth
• Description: Amphotericin B is a macrocycle antibiotic first isolated from Streptomyces nodosus. Its antifungal activity is exerted by interacting with the fungal membrane, mainly ergosterol, and inducing pore formation. The increase in membrane permeability causes loss of ions and cell death. The C-2’ hydroxyl residue of the mycosamine carbohydrate moiety in the structure seems to have a major role in binding to ergosterol. It is used in cell culture to prevent growth of microbial contaminants, such as yeast and fungi. It is recommended by the WHO and CDC as an antifungal component for VTM at a concentration of 250ug/ml.

Propriétés chimiques

• Masse moléculaire: 924.08 g/mol
• Formule: C₄₇H₇₃NO₁₇
• Couleur/Forme: Yellow Powder