PKF118-310

CAS : 84-82-2

Ref. 3D-AAA08482

Informations sur le produit

• Nom: PKF118-310
• Synonymes: 1,5,6,7-Tetrahydro-1,6-dimethylpyrimidino[5,4-e]triazine-5,7-dione, 1,6-Dimethyl-5,7-dioxo-1,5,6,7-tetrahydropyrimido[5,4-e]-as-triazine, 84-82-2, K4394, NSC 67078, Pkf 118-310, Pkf118-310, Pyrimido[5,4-e]-as-triazine-5,7(1H,6H)-dione, 1,6-dimethyl-, Sid 4251194, Toxoflavin, Toxoflavine, Xanthothricin, Xanthotricin, pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione, 1,6-dimethyl-
• CAS: 84-82-2

Description

PKF118-310 is a basic protein that has been shown to have significant cytotoxicity against the human cancer cell line K562. PKF118-310 has been shown to induce apoptosis in these cells by binding to cyclin D2, which is a protein involved in the cell cycle. PKF118-310 also inhibits production of prostaglandin E2 and tumor necrosis factor (TNF), which are important mediators of inflammation. PKF118-310 induces phase II detoxification enzymes such as glutathione reductase, cytochrome P450, and esterases through the activation of transcriptional factors such as NF-κB and AP-1. These enzymes are responsible for metabolizing toxic compounds from the body.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 193.16 g/mol
• Formule: C₇H₇N₅O₂
• Degré de pureté: Min. 95%