AZ-1355

CAS : 75451-07-9

Ref. 3D-ADA45107

Informations sur le produit

• Nom: AZ-1355
• Synonymes: Az-1355, 10,11-Dihydro-4-methoxydibenz[b,f][1,4]oxazepine-8-carboxylic acid ethyl ester, Ethyl 4-Methoxy-10,11-Dihydrodibenzo[B,F][1,4]Oxazepine-8-Carboxylate

Description

AZ-1355 is a novel, orally bioavailable, small molecule inhibitor of collagen-specific proteinase (MMP-1) that has been shown to be effective in preventing the development of cerebral amyloidosis in hamsters. AZ-1355 is orally bioavailable and penetrates the blood brain barrier, thus reducing the amount of MMP-1 that can enter the brain. This drug has also been shown to reduce cardiac collagen deposition and improve endothelial function. AZ-1355 has not been tested on humans or animals for its potential toxicity, but it does have a toxic profile in vitro. This drug has also been shown to have damaging effects on platelets and cause death in cultured cells.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 299.32 g/mol
• Formule: C₁₇H₁₇NO₄
• Degré de pureté: Min. 95%