Zika Virus NS1 Antigen Mouse Monoclonal Antibody

Ref. 3D-AZ1225

Informations sur le produit

• Nom: Zika Virus NS1 Antigen Mouse Monoclonal Antibody
• Marque: Biosynth
• Description: Purified by DEAE column chromatography and presented as a liquid in 0.015M potassium phosphate, 0.85% NaCl, pH 7.2, this mouse monoclonal antibody is complementary to the Zika NS1 protein. It is available in the IgG1k immunoglobulin subclass and is potentially suitable for used in the rapid lateral flow detection of Zika NS1 protein.Despite causing mild symptoms in most cases, the mosquito transmitted Zika virus causes a global threat in that in adults it can lead to neurological complications and Guillain-Barré syndrome and during pregnancy it can cause fetal microcephaly and congenital malformations (Zika syndrome). NS1, the protein to which this antibody is complementary, is one of seven non-structural proteins and is involved in Zika virus replication and pathogenesis. For example studies have shown that it can increase the permeability of the umbilical vein, human placentas and brain endothelial cells. It also may be possible for antibodies targeting this Zika NS1 protein to reduce the pathogensis of NS1.

Propriétés chimiques

• Degré de pureté: >90% By Sds-Page.