Etravirine - Bio-X ™

CAS : 269055-15-4

Ref. 3D-BA164437

Informations sur le produit

• Nom: Etravirine - Bio-X ™
• Synonymes: Intelence4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrileR 165335TMC 125, 4-((6-Amino-5-Bromo-2-((4-Cyanophenyl)Amino)-4-Pyrimidinyl)Oxy)-3,5-Dimethyl-Benzonitrile, 4-(6-Amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yloxy)-3,5-dimethylbenzonitrile, 4-({6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]Pyrimidin-4-Yl}Oxy)-3,5-Dimethylbenzonitrile, 4-({6-Amino-5-brom-2-[(4-cyanphenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzolcarbonitril, 4-[[6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]-4-Pyrimidinyl]Oxy]-3,5�CDimethylbenzonitrile, 4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile, 6-Amino-5-Bromo-4-(4-Cyano-2,6-Dimethylphenoxy)-2-(4-Cyanophenylamino)Pyrimidine, Benzonitrile, 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-, Etravirine [INN], Etravirine [USAN:INN], Intelence, R 165335, R165335-Tmc125, Tmc 125, Tmc125, Unii-0C50Hw4Fo1
• CAS: 269055-15-4

Description

Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) medication used in the treatment of human immunodeficiency virus (HIV) infections. It works by blocking reverse transcriptase, an enzyme essential for replication of the virus, thereby preventing the virus from multiplying and spreading. Etravirine is often used in combination with other antiretroviral drugs to effectively treat HIV/AIDS. It is commonly prescribed for patients with virus strains that are resistant to other NNRTI medications due to mutations that confer resistance- mutations K103N and Y181C. Etravirine is a diarylpyrimidine (DAPY) and has conformational isomerism meaning that it binds reverse transcriptase in an fleible manner, under multiple conformations. The impact of specific point mutations in the virus is therefore lessened.

Etravirine is part of our Bio-X™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 435.28 g/mol
• Formule: C₂₀H₁₅BrN₆O
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder