Informations sur le produit
Nom :
ACY-957
Description :
ACY-957 is a novel histone deacetylase inhibitor that inhibits the acetylation of histones and other proteins. It has been shown to have cytostatic effects on primary cells, such as human T-cell lymphomas, but not on immortalized cell lines. ACY-957 also inhibits the activity of DNA methyltransferases and can be used to profile genetic ablation in vivo. This drug also binds to the polymerase chain reaction (PCR) enzyme and blocks DNA synthesis. ACY-957 is an effective HDAC inhibitor, which has been shown to cause a dose-dependent accumulation of histone H3 acetylated at lysine 27 in mouse embryonic fibroblasts.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
429.54 g/mol
Formule :
C24H23N5OS
Degré de pureté :
Min. 95%
InChI :
InChI=1S/C24H23N5OS/c25-19-6-3-17(22-2-1-13-31-22)15-21(19)28-24(30)18-4-7-20-16(14-18)5-8-23(27-20)29-11-9-26-10-12-29/h1-8,13-15,26H,9-12,25H2,(H,28,30)
Code InChI :
InChIKey=VURDNNVAYZDGDK-UHFFFAOYSA-N
SMILES :
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2nc(N3CCNCC3)ccc2c1
MDL:
Point de fusion :
Point d'ébullition :
Point d'éclair :
Densité :
Concentration :
EINECS :
Merck :
Code SH :
