BRD 3308
CAS :
Ref. 3D-BB168411
Informations sur le produit
Nom:BRD 3308
Synonymes :
- 4-4-Acetamido-N-(2-amino-4-fluorophenyl)benzamideBRD3308
Marque:Biosynth
Description :Inhibitor of histone deacetylase 3 (HDAC3) with IC50 in nanomolar range. BRD 9908 was shown to preserve the insulin-secreting pancreatic cells in nonobese diabetic mice. BRD 3308 supressed infiltration of mononuclear cells and prevented β-cell death in vivo as well as increased basal insulin secretion in vitro. Studies on HIV infection models showed that HDAC3 inhibition by BRD 3308 disrupts the HIV latency by increasing the gene expression from HIV promoter.
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Propriétés chimiques
Masse moléculaire :287.29 g/mol
Formule :C15H14FN3O2
Degré de pureté :Min. 95%
Couleur/Forme :Powder
InChI :InChI=1S/C15H14FN3O2/c1-9(20)18-12-5-2-10(3-6-12)15(21)19-14-7-4-11(16)8-13(14)17/h2-8H,17H2,1H3,(H,18,20)(H,19,21)
Code InChI :InChIKey=RRJDFENBXIEAPD-UHFFFAOYSA-N
SMILES :CC(=O)Nc1ccc(C(=O)Nc2ccc(F)cc2N)cc1