CHIR 99021 hydrochloride

CAS : 1797989-42-4

Ref. 3D-BC162488

Informations sur le produit

• Nom: CHIR 99021 hydrochloride

Description

Potent and selective inhibitor of the glycogen synthase kinase GSK-3. Promotes cell renewal in embryonic stem cells by modulating Notch, MAPK and TGF-β signalling pathways, which are involved in pluripotency. It also affects the Wnt/β-catenin pathway and alters expression of genes coding for proteins, epigenetic regulatory elements and non-coding RNAs. The combination of CHIR 99021 and basic fibroblast growth factor (bFGF) allows long-term self-renewal in adult mouse retinal progenitor cells.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 501.8 g/mol
• Formule: C₂₂H₁₈Cl₂N₈·HCl
• Degré de pureté: Min. 95%