(2S,3S)-2-((R)-4-(4-(2-Hydroxyethoxy)phenyl)-2,5-dioxo-imidazolidin-1-yl)-3-phenyl-N-(4-propionylthiazol-2-yl)butyramide

CAS : 876755-27-0

Ref. 3D-BKB75527

Informations sur le produit

• Nom: (2S,3S)-2-((R)-4-(4-(2-Hydroxyethoxy)phenyl)-2,5-dioxo-imidazolidin-1-yl)-3-phenyl-N-(4-propionylthiazol-2-yl)butyramide
• Synonymes: RO 4927350, 1-Imidazolidineacetamide, 4-[4-(2-hydroxyethoxy)phenyl]-2,5-dioxo-N-[4-(1-oxopropyl)-2-thiazolyl]-α-[(1S)-1-phenylethyl]-, (αS,4R)-, (αS,4R)-4-[4-(2-Hydroxyethoxy)phenyl]-2,5-dioxo-N-[4-(1-oxopropyl)-2-thiazolyl]-α-[(1S)-1-phenylethyl]-1-imidazolidineacetamide, Ro 4927350, (2S,3S)-2-[(4R)-4-[4-(2-Hydroxyethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]-3-phenyl-N-(4-propionylthiazol-2-yl)butanamide

Description

(2S,3S)-2-((R)-4-(4-(2-Hydroxyethoxy)phenyl)-2,5-dioxo-imidazolidin-1-yl)-3-phenyl-N-(4-propionylthiazol-2-yl)butyramide is an aromatic ketone that has been shown to inhibit mitogen activated protein kinase (MAPK) and mitogen activated protein kinases (MAPKs). It is a potent inhibitor of the MAPK signaling pathway. This drug binds to the ATP binding site on MAPK and blocks the exchange of ATP for MgATP, which prevents the phosphorylation of tyrosine residues on MAPK. The carboxy group in this compound reacts with the primary amino group on MAPK to form a condensation product. This reaction inhibits protein synthesis by blocking the activation of ribosomes by tRNA.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 536.6 g/mol
• Formule: C₂₇H₂₈N₄O₆S
• Degré de pureté: Min. 95%