LDN 193189 dihydrochloride

CAS : 1435934-00-1

Ref. 3D-BL162781

Informations sur le produit

• Nom: LDN 193189 dihydrochloride
• Synonymes: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline 2HCl

Description

Inhibitor of ALK1, ALK2, ALK3 and ALK6 kinases and bone morphogenetic protein (BMP) pathway. LDN 1931189 is a dorsomorphin derivative that inhibits BMP-mediated activation of Smad, Akt and p38 signalling. LDN 193189 promotes differentiation of human pluripotent cells into PAX6+ anterior neural ectoderm. In combination with basic fibroblast growth factor (FGF2), LDN 193189 promotes differentiation of mouse pluripotent stem cells into inner ear sensory epithelium.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 479.4 g/mol
• Formule: C₂₅H₂₂N₆·2HCl
• Degré de pureté: Min. 95%
• Couleur/Forme: Yellow Powder