Measles Virus IgM Hybrid Human Monoclonal Antibody

Ref. 3D-BM1399

Informations sur le produit

• Nom: Measles Virus IgM Hybrid Human Monoclonal Antibody

Description

Measles is a highly contagious viral infection caused by the measles virus, a member of the Paramyxoviridae family and the Morbillivirus genus. Measles is characterized by a distinctive red rash and flu-like symptoms. The virus primarily affects children, but it can infect people of all ages. Measles is primarily transmitted through respiratory droplets when an infected person coughs or sneezes. The virus can also spread by direct contact with respiratory secretions or by touching surfaces contaminated with the virus.
Characterized disease state sera are critical components in the development and manufacture of diagnostic tests. However, sourcing of these sera is complicated, time-consuming, and sometimes suitable material is not available at all. Cymit Quimica have available the highly specific, reliable sourced Measles Virus IgM hybrid human monoclonal antibody, produced under ISO 13485 and with lot-to-lot consistency. This antibody has been produced in mice genetically modified to express human IgM heavy chain constant region. It was then concentrated and spiked into an IgG depleted and delipidised human serum matrix which ensures that the final product is as close as possible to the natural disease state IgM positive human plasma. As part of the selection process for each antibody multiple clones were analyzed by commercially available IgM assays and the clones with the most reactivity were selected for commercialization. Testing in both ELISA and bead-based applications showed this product to behave in an almost identical manner as the natural source.

• Marque: Biosynth